Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	HCFC1	93	3	96	184.833
#2	NME2	83	5	88	399.033
#3	SCAND1	68	3	71	141.243
#4	ZNF175	61	10	71	820.212
#5	CNBP	57	9	66	555.564
#6	TEAD3	54	6	60	277.75
#7	MEIS2	52	6	58	1652.458
#8	POU6F1	51	5	56	548.795
#9	TSHZ3	51	3	54	97.317
#10	NKX2-3	50	1	51	161.768
#11	HNRNPK	49	1	50	58.042
#12	FOXN2	49	11	60	1681.275
#13	MEIS1	48	2	50	36.192
#14	STAT3	48	6	54	638.723
#15	JDP2	48	10	58	1142.803
#16	AFF4	47	10	57	713.838
#17	GAS7	47	6	53	280.578
#18	SALL2	45	2	47	1788.694
#19	TADA3	45	6	51	711.326
#20	SIX5	44	3	47	903.345
#21	NFYB	44	13	57	3597.665
#22	TAF7	44	11	55	456.077
#23	STAT5B	43	7	50	1687.168
#24	CDX2	41	4	45	641.474
#25	TRIM28	41	8	49	239.523
#26	FBXW7	39	8	47	393.611
#27	CTNNB1	39	10	49	451.849
#28	MLLT10	38	11	49	21189.092
#29	ZSCAN18	37	10	47	4572.335
#30	RELA	37	5	42	1205.233
#31	NFE2L3	36	8	44	2987.348
#32	PBX3	36	4	40	88.138
#33	PHF5A	36	7	43	802.094
#34	CREBL2	34	8	42	652.279
#35	KLF10	34	5	39	2114.515
#36	HNF1B	32	8	40	6886.202
#37	MITF	32	7	39	98.007
#38	HOXB2	32	10	42	1408.838
#39	PPARD	31	11	42	1548.291
#40	RB1	31	6	37	3316.533
#41	TFE3	31	7	38	870.201
#42	TGIF1	31	14	45	1666.035
#43	NR2F6	30	10	40	2746.829
#44	ESRRA	30	6	36	235.095
#45	NPAT	30	13	43	5332.475
#46	ZNF277	30	11	41	623.58
#47	KLF9	30	12	42	2892.626
#48	ZNF187	29	6	35	1613.059
#49	LMO4	29	15	44	1990.304
#50	SATB2	29	5	34	429.967
#51	TCF7L1	29	10	39	2296.606
#52	BUD31	29	9	38	220.833
#53	ZNF498	29	13	42	394.463
#54	HOXB7	28	8	36	2939.658
#55	FOXD2	28	5	33	667.028
#56	SOX15	28	6	34	756.554
#57	FOXP1	28	10	38	251.567
#58	ASCL2	28	7	35	898.477
#59	NR3C1	28	11	39	3037.225
#60	SCMH1	27	8	35	1149.874
#61	RFX1	27	12	39	954.121
#62	TCF21	27	14	41	2770.432
#63	MLL	27	12	39	12549.493
#64	CNOT7	27	13	40	325.614
#65	HNF4G	27	11	38	1281.853
#66	ELF3	27	10	37	3853.823
#67	MYNN	26	15	41	2946.354
#68	USF1	25	11	36	3003.128
#69	RBPJ	25	16	41	1685.466
#70	FLI1	25	12	37	4884.051
#71	EDF1	25	9	34	2547.866
#72	FOXA3	25	7	32	1216.97
#73	CBFB	25	8	33	641.389
#74	SPEN	25	11	36	1155.618
#75	GATAD2B	24	8	32	3756.861
#76	FOXF1	24	8	32	115.57
#77	ZBTB17	24	12	36	326.067
#78	ZNF18	24	13	37	1682.961
#79	RUNX1T1	24	10	34	789.139
#80	TAF4	24	15	39	3813.555
#81	ZBTB48	24	9	33	811.732
#82	ZC3H8	24	8	32	2002.892
#83	SNAPC2	23	7	30	666.999
#84	MAFG	23	12	35	2999.357
#85	KLF5	23	5	28	1247.701
#86	NR5A2	23	9	32	701.604
#87	PBX1	23	13	36	6644.826
#88	E2F5	23	15	38	5370.338
#89	ZNF83	23	10	33	263.479
#90	NFXL1	23	14	37	1193.487
#91	ETV4	22	8	30	1808.01
#92	PBX2	22	12	34	2386.854
#93	SRF	22	11	33	480.705
#94	KLF6	22	13	35	543.745
#95	NFATC1	22	15	37	1428.137
#96	GTF2IRD1	22	13	35	837.874
#97	ZNF3	22	7	29	274.355
#98	SOX9	22	14	36	1990.891
#99	ZFP90	22	9	31	637.826
#100	RARB	22	16	38	1391.808
#101	GATAD1	22	12	34	485.015
#102	ZSCAN16	21	13	34	1970.468
#103	SOX10	21	12	33	853.379
#104	PFDN1	21	14	35	222.899
#105	ZNF438	21	14	35	740.326
#106	CITED2	21	10	31	1589.658
#107	PA2G4	21	11	32	1595.428
#108	TSHZ2	20	16	36	1916.697
#109	EGR1	20	14	34	917.864
#110	ZNF217	20	12	32	2492.582
#111	E2F1	20	12	32	4231.554
#112	HOXB4	20	14	34	1925.441
#113	TFAM	20	15	35	3546.711
#114	GRHL2	20	11	31	884.284
#115	UHRF1	20	6	26	3455.373
#116	MNX1	20	12	32	1487.998
#117	FOXA2	19	16	35	2265.632
#118	TFCP2L1	19	9	28	721.195
#119	HOPX	19	10	29	366.411
#120	ZNF263	19	17	36	347.817
#121	CSDA	19	13	32	2591.464
#122	ARNT2	19	9	28	1336.678
#123	TEAD4	19	11	30	3268.17
#124	PTTG1	19	9	28	1351.234
#125	HSF2	19	10	29	1305.509
#126	FOXM1	19	8	27	889.765
#127	ZNF446	19	12	31	152.232
#128	E2F7	18	11	29	2687.472
#129	BCL6	18	17	35	489.657
#130	TEAD2	18	12	30	1002.474
#131	NKX3-2	18	10	28	72.214
#132	FOXQ1	18	9	27	945.355
#133	ZNF135	18	15	33	1474.604
#134	ZNF174	18	16	34	483.367
#135	ZNF207	18	8	26	52.991
#136	ELF1	18	10	28	215.563
#137	HNRNPAB	18	17	35	1342.9
#138	PRDM1	18	16	34	2040.634
#139	TGIF2	18	13	31	3318.912
#140	STAT6	17	11	28	2825.46
#141	NR3C2	17	12	29	1774.533
#142	TCF4	17	16	33	1432.592
#143	MECOM	17	14	31	1401.135
#144	TAF12	17	12	29	741.179
#145	DDIT3	17	13	30	841.697
#146	FOXO3	17	19	36	1520.819
#147	ZNF213	17	16	33	464.125
#148	IRF6	17	11	28	1281.317
#149	CSRNP2	17	11	28	585.736
#150	TSC22D1	17	12	29	665.649
#151	SOLH	16	9	25	1140.977
#152	TFAP4	16	12	28	1413.074
#153	VDR	16	18	34	5796.338
#154	NR2C1	16	10	26	728.248
#155	GLI3	16	10	26	816.292
#156	CSRNP1	16	16	32	928.66
#157	NR1H2	16	12	28	315.355
#158	HOXB9	16	9	25	1327.371
#159	TSC22D2	15	10	25	276.683
#160	PCGF6	15	7	22	439.366
#161	ISX	15	10	25	2259.354
#162	EHF	15	15	30	2767.419
#163	HEYL	15	16	31	1157.975
#164	RUNX1	15	9	24	6281.449
#165	SOX4	15	12	27	1355.464
#166	ZNF134	15	15	30	3422.375
#167	HLF	15	10	25	2703.646
#168	SMAD4	15	14	29	23069.334
#169	HIF1A	15	11	26	1612.721
#170	RORC	15	16	31	1729.21
#171	TAF5	15	15	30	8563.798
#172	MNT	14	13	27	508.699
#173	IRF3	14	13	27	1559.043
#174	HOXB8	14	15	29	3227.067
#175	NFATC4	14	12	26	1022.542
#176	KLF11	14	17	31	5136.456
#177	RORA	14	22	36	1134.823
#178	ZNF323	14	11	25	1324.12
#179	RFXANK	14	13	27	1107.221
#180	E2F2	14	18	32	1994.896
#181	GCFC1	14	12	26	653.521
#182	KLF4	14	8	22	1217.678
#183	FOSL2	14	13	27	6546.605
#184	PRRX1	14	15	29	3007.67
#185	HOXA9	14	17	31	10226.827
#186	ELF2	14	9	23	1149.167
#187	ZNF197	14	17	31	2164.798
#188	FOXJ2	13	14	27	367.254
#189	SMAD5	13	15	28	3021.106
#190	KLF2	13	15	28	917.891
#191	MYC	13	14	27	1187.629
#192	ZNF69	13	14	27	1803.578
#193	KDM5B	13	12	25	522.984
#194	HOXD1	13	5	18	239.433
#195	TWIST1	13	14	27	7480.582
#196	STAT5A	13	16	29	1158.923
#197	HNF1A	13	15	28	1173.46
#198	SIX4	13	19	32	4968.77
#199	ADNP	13	9	22	814.224
#200	BATF	13	21	34	1954.87
#201	LASS5	13	20	33	959.917
#202	ATF2	12	5	17	820.469
#203	RNF4	12	17	29	7118.236
#204	TCF7L2	12	14	26	463.497
#205	BCL11B	12	11	23	6318.833
#206	ZSCAN21	12	19	31	4299.674
#207	CLOCK	12	17	29	577.891
#208	NFIL3	12	16	28	1207.274
#209	KLF12	12	9	21	5591.662
#210	TBX3	12	12	24	1704.933
#211	CREB1	12	8	20	22.686
#212	ETV5	12	15	27	4131.137
#213	BTAF1	12	17	29	1763.607
#214	NR2F1	12	18	30	1118.342
#215	SP140	12	7	19	2404.003
#216	SLC30A9	12	14	26	507.906
#217	MEF2D	12	15	27	827.448
#218	HDAC1	11	13	24	532.836
#219	C5orf41	11	18	29	2875.411
#220	TFCP2	11	17	28	1490.887
#221	ZHX3	11	15	26	2022.612
#222	BHLHE41	11	18	29	965.967
#223	ZFPM1	11	15	26	1739.691
#224	ETS1	11	16	27	1995.057
#225	OVOL1	11	14	25	2243.645
#226	ZNF444	11	11	22	723.108
#227	CEBPD	11	18	29	822.999
#228	RERE	11	14	25	3139.924
#229	ENO1	11	13	24	309.898
#230	TCF12	11	12	23	1140.056
#231	CEBPB	11	16	27	1069.674
#232	STAT2	11	14	25	3895.635
#233	TEF	11	16	27	594.351
#234	ZSCAN2	11	15	26	357.305
#235	JUND	11	9	20	194.316
#236	TCEAL1	10	14	24	1186.128
#237	SOX17	10	9	19	1227.895
#238	GATA3	10	22	32	2471.991
#239	POU2F1	10	11	21	6261.807
#240	NFIA	10	13	23	1470.68
#241	RELB	10	9	19	364.952
#242	MYPOP	10	15	25	561.539
#243	TCFL5	10	16	26	2169.972
#244	ZEB2	10	12	22	369.893
#245	PKNOX1	10	14	24	1423.85
#246	EBF1	10	10	20	1066.306
#247	RAX2	10	16	26	8703.365
#248	STRN3	10	16	26	418.475
#249	HES1	10	8	18	502.678
#250	PHF1	10	21	31	1426.98
#251	LASS6	10	18	28	1033.102
#252	TSC22D3	10	15	25	414.408
#253	CUX1	10	8	18	4724.294
#254	FEV	10	7	17	708.202
#255	AHCTF1	10	12	22	2016.198
#256	ZNF500	10	18	28	3606.282
#257	ZNF256	10	21	31	1122.304
#258	AEBP1	10	21	31	2079.053
#259	RARA	10	15	25	1029.084
#260	SIM2	10	10	20	1040.862
#261	PEG3	10	12	22	230.958
#262	HCLS1	9	11	20	1025.566
#263	CEBPA	9	19	28	719.873
#264	AATF	9	21	30	1368.815
#265	STAT4	9	8	17	1214.845
#266	ARID4A	9	13	22	468.774
#267	SLC26A3	9	16	25	3227.808
#268	MAX	9	11	20	294.43
#269	BATF3	9	20	29	2522.183
#270	MAFB	9	13	22	1179.471
#271	MTF1	9	11	20	2561.609
#272	E4F1	9	13	22	2315.211
#273	HAND1	9	14	23	327.968
#274	POU2F2	9	20	29	2179.304
#275	ADNP2	9	20	29	2389.779
#276	MEOX1	9	15	24	576.884
#277	RFXAP	9	6	15	210.683
#278	LEF1	9	16	25	6513.318
#279	E2F8	9	11	20	2514.628
#280	EOMES	9	14	23	1199.923
#281	BTG2	9	16	25	665.494
#282	TP53	9	18	27	2860.847
#283	GABPB1	9	14	23	610.018
#284	SOX18	9	11	20	806.44
#285	SOX11	8	13	21	1760.958
#286	MLXIPL	8	18	26	5103.881
#287	TSHZ1	8	18	26	5167.327
#288	RXRA	8	16	24	1376.962
#289	TFDP1	8	13	21	2653.193
#290	HOXA6	8	11	19	3406.266
#291	AHR	8	12	20	6363.6
#292	NFE2L1	8	15	23	1640.097
#293	POU5F1	8	14	22	533.132
#294	TCF3	8	13	21	539.139
#295	ZHX1	8	16	24	815.874
#296	MZF1	8	9	17	783.961
#297	CREB3L2	8	14	22	468.454
#298	BATF2	8	11	19	1925.898
#299	ZFHX4	8	11	19	133.627
#300	FUBP1	8	20	28	10841.761
#301	REXO4	8	19	27	1055.809
#302	CIR1	8	12	20	268.759
#303	TARDBP	8	12	20	1175.678
#304	NFKB1	8	14	22	376.044
#305	USF2	8	17	25	1749.01
#306	E2F6	8	14	22	1798.167
#307	ZKSCAN3	8	14	22	1841.632
#308	AR	8	14	22	2409.709
#309	ZFP36L1	7	16	23	961.851
#310	PPARG	7	16	23	961.386
#311	EPAS1	7	21	28	2592.149
#312	ATF5	7	18	25	3124.418
#313	MEF2C	7	13	20	1144.704
#314	ZNF394	7	10	17	322.284
#315	ZNF148	7	12	19	341.154
#316	DMRT1	7	10	17	3670.176
#317	EGR2	7	17	24	2010.257
#318	ECSIT	7	17	24	2075.754
#319	MSL3	7	14	21	1537.087
#320	MSRB2	7	11	18	1466.089
#321	CNOT8	7	11	18	173.288
#322	ELF4	7	11	18	1711.764
#323	FOXO4	7	19	26	1084.54
#324	NFIC	7	15	22	1249.086
#325	PURA	7	15	22	968.05
#326	NFYA	7	21	28	1349.733
#327	PGBD1	7	8	15	1741.108
#328	MAF	7	16	23	650.41
#329	SCML1	7	22	29	1654.309
#330	RBCK1	7	13	20	225.675
#331	UBN1	6	18	24	3928.431
#332	VENTX	6	14	20	2202.946
#333	MSX1	6	18	24	3027.456
#334	YY1	6	13	19	222.531
#335	GABPA	6	18	24	2403.663
#336	FOXP4	6	17	23	612.053
#337	ZNF71	6	12	18	2376.937
#338	RUNX3	6	13	19	945.774
#339	PAX4	6	8	14	1577.523
#340	MTA1	6	17	23	2849.506
#341	PROX1	6	19	25	3420.419
#342	LASS2	6	14	20	2930.366
#343	ZNF219	6	23	29	807.996
#344	TBX10	6	21	27	1175.92
#345	RCAN1	6	12	18	268.003
#346	LCOR	6	11	17	4368.574
#347	HEY1	6	21	27	784.735
#348	NFIX	6	17	23	255.683
#349	E2F3	6	11	17	865.487
#350	SNAPC4	6	18	24	2381.426
#351	STAT1	6	20	26	2017.706
#352	MKX	6	18	24	389.48
#353	HOXB5	6	15	21	3325.174
#354	ATF4	6	17	23	1895.215
#355	CTBP1	6	6	12	3158.067
#356	CREB5	6	20	26	786.536
#357	ZFP37	6	19	25	1856.95
#358	PLAGL2	5	21	26	2008.409
#359	ZNF35	5	13	18	622.232
#360	HOXA11	5	21	26	762.898
#361	MXD1	5	14	19	1019.08
#362	PAX8	5	16	21	1143.212
#363	PLSCR1	5	16	21	226.403
#364	DMRT2	5	15	20	2327.531
#365	CBFA2T3	5	23	28	455.259
#366	RFX3	5	8	13	280.303
#367	ZKSCAN1	5	15	20	1046.427
#368	ATF6	5	15	20	1642.388
#369	SP1	5	15	20	600.36
#370	C11orf9	5	19	24	3573.82
#371	TCF25	5	16	21	1821.865
#372	SOX13	5	20	25	943.435
#373	THRA	5	17	22	363.668
#374	FOS	5	15	20	307.542
#375	IRX1	5	10	15	378.303
#376	ZNF165	5	15	20	1466.359
#377	HES6	5	16	21	600.773
#378	CTCF	5	15	20	185.046
#379	FOSB	5	20	25	1831.977
#380	CDKN2A	5	14	19	5301.653
#381	XBP1	4	15	19	344.927
#382	FOXA1	4	15	19	1579.587
#383	SIN3A	4	15	19	121.458
#384	SOX8	4	18	22	964.789
#385	ATOH1	4	14	18	1708.356
#386	NFX1	4	18	22	283.177
#387	TBX2	4	18	22	4972.191
#388	ZFHX3	4	17	21	957.067
#389	MYT1	4	17	21	956.365
#390	SOX7	4	17	21	4486.923
#391	RFX5	4	21	25	480.187
#392	JUN	4	17	21	812.119
#393	CREB3L3	4	13	17	1200.157
#394	HMBOX1	4	18	22	1150.312
#395	SMAD6	4	10	14	243.603
#396	ARID3A	4	17	21	990.687
#397	MTA2	4	16	20	340.005
#398	PRRX2	4	13	17	2830.918
#399	ELK1	4	14	18	353.7
#400	ZNF133	4	19	23	1001.467
#401	RCOR2	4	16	20	281.986
#402	NFIB	4	18	22	638.956
#403	IRF7	4	13	17	905.854
#404	ATF3	4	12	16	363.131
#405	CREBZF	4	14	18	166.03
#406	NR1H3	4	11	15	162.621
#407	DMTF1	4	14	18	721.273
#408	ZNF281	4	23	27	1977.681
#409	ERF	4	12	16	41.847
#410	IRF1	4	18	22	257.618
#411	IKZF1	4	10	14	221.667
#412	ETS2	4	17	21	6926.39
#413	HOXA10	4	14	18	127.998
#414	PBX4	4	19	23	959.952
#415	LZTR1	3	17	20	1737.229
#416	TRIM29	3	11	14	142.169
#417	HDAC2	3	18	21	151.545
#418	GATAD2A	3	18	21	1583.174
#419	WNT5A	3	17	20	570.212
#420	PURB	3	15	18	457.057
#421	NFKB2	3	19	22	939.379
#422	TAF10	3	11	14	177.003
#423	NOLC1	3	17	20	181.313
#424	HOXA3	3	13	16	563.076
#425	HOXA13	3	17	20	1117.9
#426	ETV6	3	17	20	448.961
#427	HOXB6	3	19	22	1105.622
#428	PHTF1	3	24	27	1575.637
#429	HES5	3	19	22	814.548
#430	NFE2L2	3	18	21	1634.923
#431	FOXD1	3	14	17	4075.134
#432	RXRB	3	15	18	149.659
#433	ELF5	3	22	25	1065.4
#434	HOXD11	3	19	22	1637.642
#435	GATA2	3	17	20	74.842
#436	ZHX2	3	16	19	228.852
#437	MYCL1	3	8	11	747.933
#438	ARNTL	3	11	14	964.221
#439	SPIB	3	16	19	372.951
#440	ARNT	3	17	20	823.168
#441	IRF8	2	18	20	369.831
#442	NR1H4	2	16	18	61.177
#443	TLX2	2	13	15	122.552
#444	TRIM22	2	17	19	115.743
#445	CCRN4L	2	21	23	310.93
#446	FOXC1	2	21	23	1101.101
#447	SP3	2	20	22	1647.642
#448	TAF5L	2	18	20	1075.035
#449	HOXA5	2	19	21	1018.587
#450	FOXO1	2	16	18	180.564
#451	SPI1	2	18	20	259.012
#452	TFAP2A	2	17	19	89.133
#453	HOXD13	2	16	18	754.097
#454	IRX3	2	17	19	632.865
#455	SNAI2	2	14	16	157.953
#456	HOXA4	2	12	14	1539.571
#457	C1orf85	2	14	16	119.892
#458	ISL1	2	25	27	287.558
#459	FOXF2	2	14	16	1686.573
#460	FOXJ1	2	21	23	342.547
#461	HMGB2	2	18	20	567.149
#462	NOTCH1	2	18	20	415.527
#463	ZRANB2	2	21	23	208.08
#464	PCGF2	2	16	18	1417.741
#465	IRX2	2	16	18	102.408
#466	HOXD10	2	10	12	141.852
#467	UBP1	2	16	18	2124.52
#468	VTN	2	4	6	61.73
#469	NR1D2	2	19	21	1617.613
#470	NR4A2	1	18	19	650.439
#471	IRF9	1	16	17	192.014
#472	SREBF1	1	11	12	1062.785
#473	GTF2H3	1	24	25	2648.236
#474	E2F4	1	13	14	678.396
#475	SLC2A4RG	1	13	14	66.001
#476	HOXA2	1	14	15	146.965
#477	LHX6	1	18	19	83.102
#478	ZNF274	1	20	21	353.602
#479	HOXB13	1	14	15	139.444
#480	NPAS2	1	17	18	46.491
#481	GTF2H4	1	14	15	4219.288
#482	HOXC6	1	18	19	2789.434
#483	ZNF91	1	22	23	121.699
#484	DRAP1	1	20	21	62.804
#485	TSC22D4	1	20	21	603.989
#486	DLX1	1	9	10	82.704
#487	MESP1	1	27	28	83.957
#488	HOXC4	1	16	17	22.325
#489	ZIC2	1	17	18	2055.703
#490	SUPT4H1	1	19	20	31.904
#491	NFE2	1	16	17	42.873
#492	HOMEZ	0	17	17	0
#493	RUNX2	0	11	11	0
#494	BCL3	0	16	16	0
#495	BHLHE40	0	17	17	0
#496	TULP4	0	18	18	0
#497	TFAP2C	0	15	15	0
#498	FOSL1	0	19	19	0
#499	SREBF2	0	19	19	0
#500	RORB	0	13	13	0