Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	KDM5B	71	1	72	1363.968
#2	SOX11	71	4	75	194.602
#3	MAFB	68	5	73	6984.794
#4	TCF3	63	5	68	393.737
#5	RERE	61	6	67	433.595
#6	PPARG	58	2	60	876.342
#7	FUBP1	55	4	59	124.51
#8	NFIB	54	4	58	1309.468
#9	PTTG1	54	4	58	743.208
#10	PEG3	51	7	58	276.504
#11	CEBPA	51	2	53	90.457
#12	HOXA9	50	6	56	496.957
#13	TCF7L1	48	5	53	385.746
#14	MTA1	47	6	53	993.672
#15	HNRNPK	45	10	55	2631.969
#16	TGIF2	44	7	51	307.218
#17	LHX2	43	9	52	928.818
#18	PBX3	41	10	51	2801.381
#19	CSRNP3	40	4	44	1462.85
#20	HMG20A	40	3	43	88.736
#21	CNOT7	39	14	53	2234.283
#22	HCLS1	39	7	46	4433.108
#23	NFYA	39	7	46	169.851
#24	ELF4	37	17	54	1991.748
#25	SIM1	37	4	41	75.077
#26	TP53	37	10	47	358.034
#27	GCFC1	35	4	39	147.946
#28	HSF2	35	8	43	2884.596
#29	ADNP	35	12	47	3043.555
#30	CREBL2	35	10	45	1134.705
#31	TRIM28	33	13	46	1106.915
#32	SALL2	32	11	43	2208.964
#33	STAT5A	32	5	37	370.723
#34	TCF12	32	6	38	575.271
#35	VAV1	32	4	36	604.829
#36	ZNF236	30	5	35	353.891
#37	E2F3	30	11	41	1904.001
#38	ZNF135	30	11	41	1483.725
#39	HOXA5	30	7	37	74.785
#40	NFE2L1	30	11	41	884.17
#41	SIX1	30	10	40	779.72
#42	RXRA	30	6	36	2430.536
#43	STAT5B	30	10	40	487.746
#44	TSC22D3	29	11	40	573.422
#45	RUNX1	29	8	37	3562.217
#46	FOXM1	29	8	37	1943.207
#47	LEF1	29	8	37	2339.95
#48	BATF	29	5	34	365.426
#49	MGA	29	14	43	1131.24
#50	FOXF1	29	5	34	2526.846
#51	GAS7	28	13	41	692.579
#52	AHR	28	15	43	1254.995
#53	E2F8	28	5	33	2665.324
#54	MLXIPL	28	5	33	169.389
#55	SOX4	28	12	40	2703.003
#56	TAF4	27	8	35	619.686
#57	NR1H3	27	5	32	459.192
#58	TFE3	27	11	38	1048.768
#59	SP140	26	7	33	762.601
#60	ZNF148	26	9	35	1106.866
#61	FOSL2	26	15	41	2096.266
#62	GTF2IRD1	26	11	37	915.461
#63	TCF7	26	6	32	966.855
#64	GLI2	26	17	43	5619.966
#65	MEIS2	26	12	38	622.445
#66	KLF9	26	11	37	1884.646
#67	TFEC	25	6	31	671.034
#68	YY1	25	5	30	552.905
#69	ZNF207	25	10	35	620.892
#70	ZBTB38	25	5	30	791.266
#71	PCGF2	24	12	36	386.405
#72	E2F1	24	6	30	700.237
#73	SP3	24	12	36	1646.93
#74	RCOR1	24	13	37	1009.472
#75	HMGB2	24	12	36	745.049
#76	SMAD4	23	11	34	1586.207
#77	PKNOX2	23	12	35	772.226
#78	TCF7L2	23	14	37	999.322
#79	ZNF3	23	11	34	951.635
#80	ELF1	23	9	32	1217.638
#81	HIF1A	23	11	34	442.764
#82	FOXF2	23	13	36	3200.533
#83	MLX	23	19	42	1699.209
#84	PLAG1	23	20	43	5095.971
#85	IRF8	23	8	31	1010.601
#86	NR2F2	23	21	44	6972.282
#87	CEBPB	23	8	31	280.383
#88	XBP1	22	10	32	2580.798
#89	KLF4	22	20	42	3623.198
#90	ZNF140	22	10	32	741.045
#91	HOXA6	21	10	31	156.13
#92	HMG20B	21	16	37	2354.656
#93	ZKSCAN1	21	11	32	764.899
#94	BRD8	21	11	32	1662.559
#95	JUNB	21	10	31	471.332
#96	BACH1	21	10	31	478.918
#97	DMTF1	20	14	34	812.935
#98	NFYC	20	14	34	1862.435
#99	ELF2	20	8	28	751.691
#100	ZBTB17	20	17	37	1789.486
#101	MZF1	20	12	32	626.994
#102	PAX6	20	21	41	3956.817
#103	MSX2	20	6	26	1466.466
#104	HOXC13	20	13	33	5482.069
#105	HNF1B	20	5	25	409.635
#106	SMAD5	20	8	28	623.818
#107	KLF7	20	12	32	753.181
#108	ZEB2	19	16	35	1702.584
#109	FOXJ3	19	9	28	600.331
#110	CBFB	19	13	32	951.784
#111	HOXA10	19	11	30	811.146
#112	TFAM	19	11	30	643.694
#113	ZNF268	19	10	29	1583.694
#114	BTG2	19	14	33	2262.13
#115	ATF2	19	6	25	230.803
#116	CNBP	19	15	34	2831.203
#117	KDM5A	19	8	27	1225.487
#118	ERG	19	4	23	688.283
#119	TARDBP	19	11	30	970.982
#120	ZXDC	18	10	28	371.472
#121	SLC2A4RG	18	11	29	807.89
#122	EPAS1	18	14	32	2244.793
#123	HMGB1	18	11	29	725.255
#124	RELB	18	13	31	911.62
#125	ZNF45	18	16	34	2763.092
#126	SOX12	18	13	31	751.331
#127	ZNF219	18	11	29	594.349
#128	HLF	18	15	33	1217.514
#129	SOX10	18	8	26	629.932
#130	FOXO4	18	8	26	839.679
#131	TCF21	18	6	24	352.952
#132	FOXC2	18	5	23	344.041
#133	SUPT6H	18	7	25	476.116
#134	HOXA4	17	14	31	182.282
#135	SMAD3	17	13	30	2213.096
#136	GTF2H4	17	14	31	823.005
#137	CEBPD	17	9	26	346.109
#138	NR3C2	17	17	34	1619.121
#139	TAF10	17	13	30	1410.065
#140	RBPJ	17	9	26	732.154
#141	HOXB13	17	13	30	1704.553
#142	ZNF133	17	14	31	1101.75
#143	MAFF	17	14	31	1728.65
#144	SOX18	17	10	27	1365.176
#145	TFDP1	16	16	32	1892.56
#146	RXRG	16	11	27	334.549
#147	CREB5	16	16	32	1061.92
#148	ZSCAN18	16	9	25	12025.398
#149	HOXA3	16	11	27	590.96
#150	HNRNPAB	16	13	29	1192.405
#151	ZNF238	16	15	31	2149.285
#152	RB1	16	11	27	1177.049
#153	SOX15	16	6	22	2115.344
#154	LMO4	15	18	33	1966.896
#155	TFEB	15	14	29	1183.404
#156	USF2	15	14	29	1030.274
#157	GATAD1	15	15	30	2080.494
#158	HOPX	15	13	28	2310.14
#159	CITED1	15	12	27	183.53
#160	AR	15	17	32	1141.325
#161	TSC22D2	15	12	27	359.452
#162	BCL3	15	12	27	457.6
#163	RFXANK	15	12	27	1042.084
#164	NFAT5	15	7	22	192.394
#165	FLI1	15	9	24	1368.006
#166	FOXN3	15	15	30	1196.339
#167	KLF6	14	15	29	1234.01
#168	DDIT3	14	15	29	3895.805
#169	MAF	14	13	27	497.198
#170	ELK3	14	16	30	1883.572
#171	ZHX3	14	11	25	802.398
#172	SOX13	14	16	30	1270.334
#173	ETS2	14	16	30	825.272
#174	IRF3	14	13	27	1563.826
#175	SPI1	14	13	27	1186.634
#176	ZNF202	14	12	26	462.956
#177	TEAD4	14	12	26	2475.698
#178	BHLHE41	14	16	30	1240.196
#179	ZFP36L2	14	15	29	520.139
#180	ZBTB48	14	10	24	678.261
#181	PRDM2	14	15	29	2479.491
#182	LZTS1	13	10	23	763.015
#183	TCF20	13	15	28	2286.804
#184	MITF	13	17	30	1338.753
#185	C2orf3	13	11	24	280.166
#186	TAF5	13	20	33	1424.552
#187	SCMH1	13	9	22	124.846
#188	BCL6	13	12	25	643.415
#189	HOXB1	13	8	21	347.729
#190	HOXD3	13	11	24	3401.205
#191	MLL	13	8	21	2259.801
#192	TFAP2C	13	13	26	317.542
#193	ATF1	13	16	29	1875.771
#194	GABPA	13	15	28	1870.972
#195	TGIF1	13	15	28	593.091
#196	TRPS1	13	13	26	768.913
#197	RUNX3	13	13	26	5686.341
#198	CREB3L2	13	12	25	1383.366
#199	PKNOX1	13	17	30	1082.232
#200	ZNF500	13	9	22	190.175
#201	BHLHE40	13	15	28	602.357
#202	FOXD2	13	10	23	2444.924
#203	MECOM	13	15	28	415.941
#204	CTNNB1	13	18	31	1077.814
#205	SLC30A9	13	11	24	1703.416
#206	SPIB	12	9	21	744.849
#207	NFIX	12	12	24	1802.007
#208	FOXO3	12	10	22	747.157
#209	PRDM1	12	14	26	1189.976
#210	NR4A3	12	12	24	1845.212
#211	NR2C1	12	19	31	7182.355
#212	MNT	12	15	27	890.271
#213	PHF1	12	16	28	1427.925
#214	TBX3	12	16	28	479.616
#215	TCEAL1	12	11	23	651.01
#216	ZNF131	12	19	31	1588.938
#217	HOXA2	12	9	21	685.925
#218	ENO1	12	24	36	3409.645
#219	ZNF91	12	20	32	1250.501
#220	NFATC4	12	10	22	989.412
#221	RXRB	12	13	25	1635.422
#222	ETV1	12	21	33	2309.798
#223	NFIL3	12	12	24	910.056
#224	ZNF167	12	16	28	284.271
#225	HOXC8	12	9	21	1711.088
#226	GATA3	12	16	28	2542.22
#227	PA2G4	12	18	30	2540.799
#228	WT1	12	14	26	1590.369
#229	ZFHX3	12	11	23	586.735
#230	ELF5	12	13	25	452.486
#231	FBXW7	12	16	28	1168.297
#232	CBFA2T2	12	19	31	803.879
#233	TBP	12	9	21	212.666
#234	MSC	12	15	27	2054.473
#235	NR2F1	12	19	31	3792.712
#236	PRRX1	12	16	28	346.488
#237	FOSB	12	9	21	1281.856
#238	MYNN	11	10	21	863.395
#239	HIF3A	11	17	28	845.108
#240	SCML2	11	14	25	3114.406
#241	PHTF1	11	21	32	1379.727
#242	JUN	11	14	25	859.076
#243	ZNF217	11	20	31	846.416
#244	MEIS3P1	11	12	23	1222.428
#245	RUNX1T1	11	18	29	1011.311
#246	RARB	11	16	27	943.336
#247	ATF3	11	7	18	358.297
#248	IKZF1	11	10	21	1106.155
#249	GLI3	11	15	26	1373.35
#250	CITED2	11	24	35	1855.955
#251	NFKB1	11	14	25	1298.221
#252	THRA	11	16	27	456.001
#253	HHEX	11	8	19	291.739
#254	MSL3	11	13	24	1790.061
#255	NR3C1	11	14	25	1163.832
#256	ADNP2	11	17	28	676.356
#257	NKX3-1	11	9	20	1129.451
#258	SOLH	11	16	27	1193.861
#259	TCF4	11	19	30	1729.621
#260	NFE2L3	10	12	22	778.241
#261	GATA6	10	16	26	2010.534
#262	VDR	10	18	28	1099.663
#263	PBX1	10	21	31	13358.906
#264	JUND	10	21	31	2488.612
#265	CREM	10	14	24	796.755
#266	NFYB	10	17	27	3441.368
#267	CREB3L1	10	21	31	1483.592
#268	HDAC2	10	21	31	636.698
#269	STRN3	10	14	24	793.268
#270	ZNF274	10	15	25	967.125
#271	TAF12	10	10	20	1097.411
#272	UBN1	10	13	23	1720.447
#273	GTF2I	10	10	20	274.228
#274	TSHZ2	10	15	25	1196.17
#275	LZTR1	10	13	23	1605.679
#276	TAL1	10	10	20	1600.888
#277	TSC22D4	10	10	20	681.124
#278	ZNF394	10	19	29	1414.742
#279	E4F1	10	8	18	488.753
#280	MTF1	10	15	25	1151.921
#281	DLX4	9	13	22	2609.202
#282	KLF2	9	14	23	991.461
#283	NR2F6	9	20	29	654.628
#284	CUX1	9	19	28	1843.906
#285	MEF2C	9	14	23	1524.455
#286	DRAP1	9	17	26	1768.338
#287	LASS2	9	11	20	1152.808
#288	HOXD4	9	13	22	696.727
#289	ZNF93	9	14	23	461.221
#290	EGR1	9	7	16	666.259
#291	RBCK1	9	12	21	1040.814
#292	HOXD10	9	13	22	3060.772
#293	FOS	9	10	19	521.388
#294	SMAD1	9	15	24	779.752
#295	NR4A2	9	9	18	627.722
#296	PLSCR1	9	15	24	1650.175
#297	CREBZF	9	15	24	409.262
#298	BACH2	9	19	28	1020.519
#299	ZNF24	9	14	23	818.089
#300	ZFHX4	9	22	31	2165.149
#301	CDKN2A	9	20	29	822.707
#302	ZNF117	9	11	20	2228.819
#303	ESR1	9	20	29	586.614
#304	HDAC1	8	18	26	1272.023
#305	TCFL5	8	17	25	1518.619
#306	GATAD2A	8	12	20	513.507
#307	CREBBP	8	18	26	646.571
#308	NR4A1	8	7	15	1534.476
#309	SCML1	8	19	27	1638.2
#310	FOXO1	8	16	24	644.392
#311	SNAPC4	8	20	28	1246.343
#312	STAT3	8	13	21	1558.313
#313	TEAD1	8	18	26	773.212
#314	SMAD2	8	17	25	373.324
#315	POU6F1	8	10	18	1268.144
#316	STAT1	8	7	15	221.077
#317	SATB2	8	22	30	1264.634
#318	RCAN1	8	26	34	1831.503
#319	NFIC	8	13	21	765.129
#320	IRX5	8	17	25	1490.992
#321	HMGA1	8	21	29	882.836
#322	HIC1	8	14	22	739.887
#323	CSDA	8	18	26	1664.167
#324	ZNF75D	8	15	23	828.103
#325	HES1	8	23	31	1506.324
#326	TCF15	8	11	19	322
#327	PPARD	8	13	21	1322.559
#328	SNAPC5	8	13	21	1587.587
#329	BLZF1	8	11	19	1211.148
#330	EN1	8	19	27	562.912
#331	NANOG	8	20	28	428.157
#332	ZNF83	8	23	31	853.104
#333	ARNTL2	8	17	25	1010.69
#334	ERF	8	12	20	857.002
#335	STAT4	8	15	23	625.368
#336	GTF2H3	8	14	22	1062.261
#337	POU2F2	8	13	21	510.991
#338	NKX3-2	8	19	27	2719.557
#339	TBX1	7	11	18	294.995
#340	TEAD3	7	19	26	797.225
#341	PURA	7	16	23	674.43
#342	DBP	7	16	23	724.762
#343	NOLC1	7	16	23	444.031
#344	YEATS4	7	26	33	1936.437
#345	ZNF85	7	12	19	378.715
#346	SIM2	7	16	23	1491.2
#347	ZNF187	7	14	21	214.721
#348	SCAND1	7	13	20	1107.403
#349	BCL11B	7	13	20	874.846
#350	ECSIT	7	12	19	943.637
#351	REST	7	13	20	786.1
#352	NR5A2	7	14	21	742.426
#353	ZNF189	7	13	20	2043.485
#354	HOXC4	7	18	25	1081.241
#355	RFX5	7	18	25	1156.157
#356	IRF1	7	11	18	521.831
#357	PITX2	7	16	23	1440.882
#358	C11orf9	7	13	20	3041.405
#359	MMP14	7	18	25	2244.977
#360	IRF9	7	6	13	120.095
#361	SUPT4H1	7	18	25	1485.74
#362	ARNT	7	16	23	3058.735
#363	EDF1	7	15	22	338.303
#364	MLLT10	7	12	19	215.835
#365	RARA	7	12	19	942.857
#366	HIRA	7	18	25	1114.864
#367	RORA	6	12	18	1093.25
#368	TBX2	6	18	24	1136.363
#369	MEOX2	6	21	27	4175.571
#370	NFATC1	6	16	22	758.094
#371	CSRNP2	6	10	16	1340.455
#372	SALL1	6	22	28	1362.09
#373	TFDP2	6	12	18	180.947
#374	IRF2	6	20	26	903.103
#375	ARNT2	6	16	22	750.959
#376	FOSL1	6	22	28	1327.562
#377	REL	6	17	23	1114.361
#378	YBX1	6	20	26	1967.166
#379	NFE2L2	6	16	22	587.954
#380	FOXE1	6	10	16	535.189
#381	UBP1	6	23	29	1126.119
#382	SREBF1	6	11	17	1347.675
#383	HOXB6	6	13	19	249.231
#384	ZFP36L1	6	22	28	765.544
#385	PLAGL2	6	19	25	3191.363
#386	ZFPM2	6	27	33	553.029
#387	GABPB1	6	16	22	689.936
#388	IRF7	6	13	19	320.317
#389	PBX2	6	17	23	532.441
#390	TP63	6	11	17	407.787
#391	HOXC11	6	8	14	108.042
#392	RARG	6	15	21	942.334
#393	WNT5A	6	25	31	779.432
#394	ZNF193	6	16	22	305.086
#395	MSX1	6	20	26	541.671
#396	MEF2A	6	20	26	2223.229
#397	HMBOX1	5	16	21	526.585
#398	SOX2	5	13	18	810.617
#399	FOXK2	5	18	23	447.811
#400	TFCP2	5	14	19	4845.008
#401	HOXD9	5	13	18	1686.637
#402	ATF5	5	18	23	921.281
#403	HOXC5	5	12	17	1049.007
#404	TSC22D1	5	23	28	1020.751
#405	SPEN	5	11	16	648.108
#406	MEIS1	5	18	23	1208.96
#407	SOX17	5	17	22	404.469
#408	PRRX2	5	16	21	636.905
#409	CNOT8	5	18	23	1233.196
#410	AATF	5	18	23	1213.951
#411	STAT2	5	15	20	990.378
#412	IRF5	5	15	20	626.884
#413	HSF1	5	17	22	929.795
#414	ZNF323	5	13	18	1753.24
#415	HOXD11	5	11	16	1520.629
#416	NCOR1	5	20	25	1422.855
#417	FOXG1	5	16	21	1730.757
#418	ZIC1	5	20	25	1298.896
#419	TBX5	5	16	21	243.717
#420	HOXB5	5	20	25	993.667
#421	KLF10	5	16	21	424.472
#422	STAT6	5	23	28	1075.073
#423	HOXC10	5	19	24	815.188
#424	MEOX1	5	17	22	848.196
#425	TADA3	5	15	20	1130.206
#426	ATF4	5	16	21	729.79
#427	ZEB1	5	17	22	866.397
#428	ATF6	5	17	22	999.293
#429	BUD31	4	21	25	702.865
#430	ETV5	4	17	21	368.274
#431	ZNF232	4	14	18	919.259
#432	AFF1	4	18	22	516.842
#433	HEY2	4	23	27	1114.497
#434	FOXJ2	4	13	17	437.269
#435	SMAD6	4	19	23	253.542
#436	BTAF1	4	17	21	1337.863
#437	KLF11	4	19	23	815.1
#438	ZHX2	4	16	20	1152.62
#439	SRF	4	17	21	823.263
#440	TFAP2A	4	17	21	538.15
#441	ZNF281	4	24	28	1290.743
#442	NR1D2	4	13	17	249.031
#443	HEY1	4	19	23	1185.159
#444	ZNF277	4	23	27	907.879
#445	TRIM22	4	17	21	486.585
#446	EGR2	4	13	17	150.015
#447	POU2F1	4	17	21	1661.07
#448	ISL1	4	16	20	479.897
#449	RNF4	4	20	24	2418.21
#450	MYF6	4	12	16	270.728
#451	NR1H2	4	12	16	457.372
#452	CREB3	4	15	19	361.81
#453	NPAT	4	22	26	769.589
#454	TBX19	4	16	20	1763.76
#455	MAFG	4	16	20	1050.313
#456	MSRB2	4	23	27	1397.387
#457	TCF25	4	18	22	543.529
#458	FOXC1	4	18	22	549.534
#459	AHCTF1	3	12	15	352.433
#460	SOX9	3	22	25	513.287
#461	LASS6	3	20	23	1238.313
#462	ZGPAT	3	14	17	310.657
#463	GATA2	3	16	19	871.474
#464	BATF3	3	16	19	1060.547
#465	KLF12	3	14	17	245.271
#466	MAX	3	17	20	673.67
#467	MYC	3	27	30	415.334
#468	TAF7	3	17	20	490.906
#469	ALX1	3	22	25	286.958
#470	IRF4	3	18	21	244.438
#471	SNAI2	3	22	25	509.644
#472	KLF5	3	15	18	1476.805
#473	NOTCH1	3	15	18	210.694
#474	E2F6	3	19	22	445.734
#475	ESRRG	3	18	21	3077.42
#476	TFAP2B	2	14	16	251.174
#477	FOXD1	2	28	30	186.169
#478	CUX2	2	8	10	90.839
#479	HOXA1	2	21	23	354.505
#480	ARNTL	2	21	23	506.457
#481	TULP4	2	17	19	503.117
#482	LHX6	2	18	20	110.745
#483	SREBF2	2	15	17	196.945
#484	ASCL1	2	11	13	1074.279
#485	HAND1	2	16	18	199.514
#486	SIX2	2	23	25	386.389
#487	HOXB7	2	26	28	555.39
#488	TWIST1	2	20	22	579.21
#489	HMGA2	2	22	24	1189.217
#490	NPAS2	1	28	29	223.868
#491	HOXB2	1	15	16	203.731
#492	CTBP1	1	14	15	157.645
#493	NFATC3	1	18	19	141.456
#494	AEBP1	1	21	22	80.464
#495	CREB1	1	23	24	214.075
#496	EGR3	1	15	16	72.451
#497	HOXA11	1	19	20	31.176
#498	PITX1	0	17	17	0
#499	SATB1	0	23	23	0
#500	MYF5	0	9	9	0