Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	RARG	37	0	37	0
#2	PRRX2	32	2	34	1214.597
#3	ATF2	31	6	37	911.662
#4	IRF2	29	5	34	685.663
#5	ATF1	28	3	31	696.266
#6	HMX1	25	1	26	1192.214
#7	NKX3-1	24	1	25	37.263
#8	MLXIPL	24	3	27	737.993
#9	CTCF	23	3	26	1697.128
#10	NFYC	23	10	33	1167.426
#11	SP3	22	5	27	1331.837
#12	HNF1B	22	2	24	58.593
#13	NPAS2	21	7	28	1987.469
#14	NFE2L2	21	7	28	2100.536
#15	NPAT	21	7	28	4060.394
#16	FOSL2	21	5	26	2882.029
#17	PITX3	21	8	29	1541.072
#18	PAX8	21	7	28	559.206
#19	SNAPC5	21	8	29	4136.716
#20	ELK1	20	6	26	483.271
#21	PKNOX2	20	0	20	0
#22	FOXO1	20	6	26	1966.275
#23	ZNF287	19	3	22	3408.968
#24	CREBBP	19	9	28	2375.355
#25	TAF5	19	10	29	1815.402
#26	FOXN3	19	12	31	4473.131
#27	DLX4	19	2	21	438.777
#28	CREBZF	19	6	25	2919.699
#29	ETS2	18	7	25	2660.009
#30	RELB	18	4	22	1831.198
#31	CDX2	18	2	20	31.228
#32	HOXC11	18	4	22	3670.01
#33	ATF4	18	10	28	2107.618
#34	PCGF2	17	8	25	950.571
#35	MAFF	17	10	27	2367.863
#36	HOXB1	17	8	25	1822.469
#37	IRF1	17	10	27	3342.437
#38	HOXA5	17	4	21	1248.462
#39	GBX1	17	6	23	983.951
#40	RELA	17	6	23	1114.352
#41	DLX2	17	8	25	3850.85
#42	CIR1	16	10	26	4232.462
#43	SMAD4	16	9	25	678.572
#44	T	16	5	21	1763.226
#45	ETV6	16	6	22	3389.973
#46	TRIM28	16	7	23	3028.556
#47	ZKSCAN1	16	4	20	770.619
#48	EMX1	16	9	25	2132.463
#49	HDAC2	16	10	26	709.664
#50	LASS2	16	3	19	655.249
#51	BLZF1	16	7	23	5133.372
#52	TAF4	16	9	25	1815.081
#53	FOXJ3	15	11	26	4025.273
#54	GCFC1	15	12	27	3167.651
#55	RAX	15	5	20	349.505
#56	MLX	15	8	23	1896.437
#57	SLC2A4RG	15	5	20	1997.704
#58	ZNF236	15	5	20	2540.23
#59	BTAF1	15	7	22	4770.458
#60	STRN3	15	9	24	1025.053
#61	KLF9	15	9	24	1378.733
#62	TFE3	15	9	24	3019.262
#63	ECSIT	15	2	17	758.029
#64	TCF25	15	10	25	4105.578
#65	HMG20A	14	10	24	2079.469
#66	ADNP	14	9	23	1110.094
#67	SOX10	14	6	20	1085.223
#68	KLF6	14	8	22	1555.498
#69	ZNF444	14	8	22	876.811
#70	E2F6	14	5	19	3527.306
#71	SLC30A9	14	14	28	2660.056
#72	ZNF189	14	10	24	787.554
#73	HNRNPAB	14	7	21	1010.064
#74	NFYB	14	8	22	782.821
#75	ETV4	14	4	18	71.574
#76	GLI3	14	5	19	485.734
#77	PHF1	13	12	25	2946.76
#78	ZNF165	13	14	27	5742.533
#79	PHTF1	13	14	27	6020.312
#80	BHLHE41	13	6	19	1911.195
#81	BCL3	13	5	18	744.156
#82	ZFP36L1	13	14	27	2850.32
#83	FLI1	13	6	19	740.459
#84	HNRNPK	13	7	20	2205.706
#85	FOXA2	13	4	17	103.711
#86	TCF12	13	7	20	1048.1
#87	YEATS4	13	7	20	1817.69
#88	ZNF175	13	7	20	1205.658
#89	FOSB	13	5	18	1972.843
#90	NCOR1	13	10	23	2625.032
#91	FOXL1	13	7	20	1872.34
#92	ZNF232	13	12	25	2999.577
#93	RCOR1	13	10	23	1727.409
#94	TRIM29	13	4	17	217.278
#95	YY1	13	8	21	3003.191
#96	CREB1	12	15	27	1505.595
#97	EVX1	12	3	15	186.453
#98	MITF	12	9	21	2955.958
#99	MAFG	12	4	16	1559.127
#100	ETV7	12	8	20	9107.64
#101	REST	12	7	19	792.345
#102	MEF2A	12	9	21	2226.941
#103	BATF	12	6	18	924.518
#104	NR1I2	12	8	20	1306.355
#105	BACH1	12	10	22	2959.028
#106	EGR4	12	4	16	380.867
#107	ZNF75D	12	11	23	2477.806
#108	SIX5	12	9	21	681.066
#109	PAX7	12	8	20	1874.56
#110	E2F4	12	4	16	157.968
#111	RORC	12	5	17	350.322
#112	MGA	12	7	19	1117.024
#113	HMGB2	11	11	22	1599.205
#114	SPDEF	11	5	16	868.291
#115	JUND	11	7	18	1503.232
#116	KLF7	11	10	21	1604.154
#117	TSC22D2	11	8	19	2563.189
#118	CSRNP2	11	9	20	633.211
#119	ZNF24	11	12	23	1206.386
#120	HOXA3	11	3	14	107.283
#121	SALL2	11	10	21	5529.788
#122	BUD31	11	7	18	867.683
#123	HSF4	11	13	24	2925.278
#124	LASS6	11	6	17	1403.089
#125	LZTR1	11	7	18	1950.209
#126	SOX15	11	4	15	1569.275
#127	HOXC4	11	10	21	2442.961
#128	ELK4	11	10	21	1371.458
#129	ZNF3	11	6	17	1242.839
#130	AHR	11	8	19	2998.149
#131	ZSCAN16	11	9	20	2360.688
#132	HSF2	11	7	18	413.755
#133	CREB3L1	11	8	19	972.264
#134	RERE	11	15	26	4407.649
#135	KLF2	11	6	17	991.279
#136	IRF4	11	8	19	1126.446
#137	TP53	11	11	22	2197.277
#138	ELF1	11	8	19	1000.394
#139	MYT1L	11	4	15	1137.445
#140	RARA	11	8	19	1287.2
#141	UBP1	10	7	17	613.532
#142	NFATC1	10	10	20	2997.304
#143	ZSCAN18	10	8	18	1395.879
#144	NOTCH1	10	7	17	2187.849
#145	SMAD6	10	10	20	2203.645
#146	IRF3	10	10	20	2377.466
#147	HINFP	10	8	18	1200.412
#148	ZKSCAN5	10	8	18	2386.867
#149	RBPJ	10	10	20	661.648
#150	SCML2	10	6	16	570.918
#151	LHX3	10	5	15	818.359
#152	PRDM2	10	6	16	496.028
#153	KDM5A	10	9	19	676.215
#154	SCRT1	10	8	18	2099.158
#155	RXRB	10	9	19	947.233
#156	HOXA7	10	4	14	465.794
#157	RB1	10	8	18	1817.167
#158	FOXB1	10	6	16	1189.332
#159	GABPA	10	5	15	1529.794
#160	RFXANK	10	11	21	2759.273
#161	FOXO4	10	6	16	2090.509
#162	MEF2C	10	4	14	601.076
#163	MMP14	10	6	16	940.083
#164	STAT2	10	6	16	1377.645
#165	TFCP2L1	10	5	15	1050.282
#166	GATA1	10	9	19	1127.799
#167	HMGA1	10	10	20	2181.183
#168	MNT	9	10	19	3920.051
#169	SOX9	9	7	16	2470.999
#170	FOXK2	9	5	14	2102.493
#171	ZNF93	9	5	14	1140.449
#172	HAND1	9	6	15	2393.388
#173	ZNF217	9	14	23	1164.771
#174	ETV2	9	10	19	1648.26
#175	ZNF281	9	11	20	1724.79
#176	TBX21	9	8	17	2005.12
#177	LMO4	9	8	17	1397.536
#178	MTF1	9	8	17	2295.817
#179	CUX1	9	7	16	1862.92
#180	HMGB1	9	11	20	2632.92
#181	ZEB1	9	10	19	324.117
#182	TFAM	9	13	22	1355.152
#183	NR2C1	9	6	15	821.324
#184	TFAP2C	9	6	15	1588.38
#185	HOXB7	9	6	15	621.401
#186	ZNF83	9	9	18	1493.331
#187	ZNF274	9	12	21	2062.955
#188	E2F8	9	5	14	1052.891
#189	USF2	9	8	17	531.771
#190	NKX2-5	9	9	18	535.307
#191	TCF7L2	9	9	18	5918.102
#192	REL	9	8	17	1761.316
#193	PA2G4	9	8	17	1768.731
#194	TAF12	9	6	15	865.308
#195	ARID4A	9	13	22	2023.8
#196	TCF15	9	5	14	1848.439
#197	ADNP2	8	10	18	687.159
#198	ZNF202	8	7	15	931.183
#199	MXD1	8	7	15	1475.83
#200	POU2F2	8	9	17	1172.316
#201	PBX2	8	10	18	1457.766
#202	MAFB	8	7	15	1914.4
#203	SREBF2	8	8	16	2928.706
#204	MAF	8	7	15	820.647
#205	ZNF140	8	9	17	789.708
#206	ZNF394	8	6	14	1037.353
#207	NR3C2	8	9	17	1112.566
#208	ARNTL	8	7	15	1962.242
#209	ATF6	8	8	16	1642.931
#210	ESRRA	8	5	13	427.783
#211	NR3C1	8	10	18	758.456
#212	MEIS1	8	8	16	1416.255
#213	TFEC	8	7	15	1685.842
#214	PLSCR1	8	10	18	1079.665
#215	TFCP2	8	7	15	532.596
#216	TARDBP	8	8	16	2961.194
#217	NR5A1	8	9	17	589.052
#218	ARNT2	8	9	17	1478.569
#219	TCEAL1	8	6	14	1873.252
#220	HIC1	8	8	16	2393.575
#221	IRF9	8	7	15	1339.172
#222	ZNF643	8	5	13	855.477
#223	RXRA	8	9	17	2012.252
#224	NFE2L3	8	9	17	1213.714
#225	MLL	8	11	19	2008.713
#226	SMAD5	8	10	18	3215.447
#227	GTF2H4	8	9	17	1329.577
#228	NR1D2	8	13	21	1717.782
#229	TCF20	8	4	12	229.707
#230	NFKB1	7	5	12	1065.061
#231	TCF4	7	10	17	3043.624
#232	CITED2	7	8	15	1246.503
#233	HOXA9	7	6	13	490.844
#234	OVOL1	7	7	14	569.367
#235	KLF10	7	10	17	1345.569
#236	ELF2	7	10	17	1569.054
#237	KLF11	7	9	16	856.24
#238	AHCTF1	7	7	14	377.09
#239	KLF3	7	12	19	1065.696
#240	HOXA10	7	7	14	821.585
#241	PEG3	7	9	16	1371.048
#242	SPEN	7	11	18	979.752
#243	ZGPAT	7	9	16	1279.791
#244	PFDN1	7	4	11	706.543
#245	CREB3L2	7	11	18	1598.357
#246	PLAGL2	7	6	13	1075.317
#247	KDM5B	7	5	12	694.925
#248	BATF3	7	7	14	2077.042
#249	TSHZ2	7	7	14	1441.146
#250	CREBL2	7	10	17	3321.094
#251	PBX1	7	8	15	1468.25
#252	IRF8	7	8	15	1998.81
#253	TFDP2	7	6	13	997.606
#254	MZF1	7	8	15	1499.838
#255	PURA	7	12	19	1205.886
#256	HNF4A	7	6	13	747.508
#257	SNAPC2	7	10	17	1577.096
#258	PITX1	7	8	15	1238.381
#259	ZKSCAN4	7	9	16	1735.929
#260	NEUROD2	7	8	15	1273.638
#261	FUBP1	7	12	19	4802.25
#262	CNOT8	7	8	15	725.035
#263	TULP4	7	10	17	719.262
#264	CBFA2T3	7	8	15	861.477
#265	FOXN1	7	6	13	220.394
#266	GATA2	7	7	14	499.173
#267	DMTF1	7	7	14	1371.123
#268	NR4A1	7	10	17	3583.753
#269	FOXO3	7	8	15	822.177
#270	ATF3	7	10	17	1899.586
#271	ZBTB38	7	5	12	644.797
#272	GABPB1	7	10	17	1775.942
#273	HEY1	7	11	18	2005.702
#274	HIRA	7	10	17	882.879
#275	ZSCAN5A	7	6	13	547.831
#276	TSC22D3	7	3	10	284.966
#277	TRIM25	7	9	16	2599.459
#278	SNAPC4	6	13	19	721.869
#279	MYC	6	15	21	1957.911
#280	BHLHE40	6	14	20	1833.542
#281	FOS	6	11	17	1470.067
#282	STAT1	6	11	17	1143.081
#283	EGR1	6	8	14	1132.034
#284	MTA1	6	9	15	1367.028
#285	EPAS1	6	8	14	924.558
#286	NFKB2	6	10	16	1502.315
#287	PTTG1	6	10	16	1261.276
#288	XBP1	6	9	15	669.135
#289	KLF5	6	8	14	1821.618
#290	FBXW7	6	10	16	1300.66
#291	HEY2	6	13	19	4703.39
#292	ETV5	6	10	16	2512.648
#293	PRDM1	6	10	16	964.623
#294	TCF3	6	10	16	1535.763
#295	TFEB	6	5	11	1307.061
#296	HOXD1	6	6	12	1021.419
#297	ZHX2	6	14	20	2089.361
#298	SMAD3	6	12	18	1865.642
#299	ZNF45	6	9	15	1838.826
#300	MEIS3P1	6	10	16	2216.454
#301	GTF2I	6	7	13	1089.028
#302	RUNX1T1	6	6	12	1032.106
#303	NOLC1	6	9	15	1881.732
#304	TGIF2	6	8	14	1200.111
#305	RFX5	6	11	17	2869.026
#306	POU2F1	6	9	15	1661.257
#307	NR1H2	6	6	12	722.756
#308	TRPS1	6	5	11	888.087
#309	CNBP	6	9	15	428.949
#310	SCAND1	6	10	16	997.597
#311	ZNF133	6	11	17	1504.385
#312	IRF5	6	7	13	1606.179
#313	ELF3	6	10	16	565.164
#314	TAF5L	6	8	14	1859.2
#315	SOX21	6	11	17	2760.427
#316	MYNN	6	8	14	729.922
#317	SOX13	6	6	12	416.024
#318	SUPT4H1	6	9	15	4346.997
#319	RARB	6	7	13	478.599
#320	GSC2	6	7	13	1261.973
#321	TBX2	6	4	10	254.303
#322	NFE2L1	5	12	17	3140.329
#323	C11orf9	5	7	12	308.657
#324	ESRRG	5	13	18	2790.985
#325	SUPT6H	5	4	9	676.81
#326	CEBPA	5	7	12	1698.141
#327	HOXA1	5	7	12	324.966
#328	HES1	5	6	11	700.288
#329	NFAT5	5	11	16	1378.764
#330	MSC	5	9	14	694.559
#331	HDAC1	5	9	14	1076.353
#332	SMAD2	5	8	13	701.876
#333	PBX3	5	6	11	977.584
#334	STAT4	5	7	12	1007.619
#335	ZNF238	5	14	19	1013.276
#336	ARID3A	5	7	12	1055.841
#337	SIX1	5	9	14	510.477
#338	FOXM1	5	6	11	592.977
#339	RORA	5	10	15	856.938
#340	IRF7	5	6	11	270.56
#341	ESR1	5	14	19	1091.31
#342	CDKN2A	5	6	11	527.687
#343	STAT3	5	11	16	892.781
#344	NR1H3	5	9	14	1543.8
#345	AFF4	5	6	11	684.23
#346	RNF4	5	13	18	1503.44
#347	KLF4	5	14	19	1357.22
#348	ATF6B	5	8	13	570.429
#349	NPAS1	5	10	15	1020.318
#350	NFATC4	5	8	13	697.006
#351	ZBTB48	5	5	10	671.171
#352	DDIT3	5	10	15	1909.22
#353	HAND2	5	6	11	371.265
#354	MAFK	5	9	14	1056.85
#355	BACH2	5	6	11	578.782
#356	FOXN2	5	11	16	1004.338
#357	TP73	5	8	13	1309.354
#358	MAX	5	8	13	1470.855
#359	E2F3	5	15	20	1036.053
#360	CREM	5	11	16	2976.458
#361	VDR	5	11	16	1073.5
#362	ZNF187	5	12	17	1746.031
#363	NR4A2	5	13	18	2191.666
#364	HSF1	4	7	11	919.105
#365	TSC22D4	4	7	11	400.25
#366	MEF2D	4	10	14	798.127
#367	C2orf3	4	9	13	850.272
#368	SPI1	4	9	13	379.03
#369	IKZF1	4	9	13	371.783
#370	RUNX1	4	7	11	419.851
#371	EDF1	4	8	12	462.007
#372	POU4F1	4	8	12	939.8
#373	RCAN1	4	10	14	1777.013
#374	CBFB	4	16	20	3409.247
#375	MLLT10	4	11	15	1999.908
#376	NFE2	4	8	12	1004.651
#377	SATB2	4	10	14	613.17
#378	EGR3	4	7	11	859.377
#379	ZNF434	4	9	13	585.274
#380	SREBF1	4	8	12	4031.192
#381	CLOCK	4	6	10	754.974
#382	ETS1	4	7	11	773.053
#383	HOXA6	4	7	11	878.947
#384	TAF4B	4	8	12	1231.349
#385	E2F5	4	9	13	156.765
#386	CEBPD	4	12	16	1847.859
#387	CITED1	4	9	13	131.422
#388	ARNT	4	6	10	614.239
#389	TCFL5	4	11	15	713.332
#390	CEBPB	4	10	14	1385.598
#391	HOPX	4	7	11	889.242
#392	FOXJ2	4	8	12	1500.831
#393	TBP	4	5	9	356.538
#394	ZFPM2	4	6	10	1271.103
#395	TSC22D1	4	14	18	1941.846
#396	HNF1A	4	11	15	441.36
#397	SATB1	4	13	17	1525.488
#398	ZBTB17	4	8	12	1065.573
#399	ZNF91	4	12	16	1464.679
#400	SP1	4	6	10	345.574
#401	JUN	4	12	16	1211.614
#402	ZBTB25	4	8	12	384.46
#403	ZFP36L2	4	15	19	1266.234
#404	HIF1A	4	9	13	718.412
#405	TADA3	4	5	9	356.496
#406	NFIC	4	8	12	661.761
#407	NR2F6	4	7	11	268.135
#408	CREB3	4	8	12	1172.238
#409	TAF6	4	12	16	956.823
#410	GATA3	4	9	13	1425.728
#411	YBX1	3	7	10	373.397
#412	NFX1	3	5	8	1209.995
#413	HCLS1	3	10	13	494.283
#414	NFIL3	3	8	11	683.566
#415	ZNF131	3	12	15	842.385
#416	VAV1	3	11	14	1564.897
#417	TFAP2A	3	6	9	348.661
#418	SOLH	3	9	12	1047.215
#419	AEBP1	3	7	10	501.464
#420	FOXA1	3	4	7	702.178
#421	TRIM22	3	13	16	1170.999
#422	WNT5A	3	9	12	802.915
#423	HMG20B	3	11	14	1002.902
#424	TAF7	3	4	7	268.563
#425	ENO1	3	6	9	672.327
#426	NFATC3	3	10	13	823.719
#427	ETV1	3	12	15	1232.126
#428	ZNF148	3	9	12	258.56
#429	ZNF323	3	12	15	1567.715
#430	ZNF117	3	9	12	816.38
#431	FOXD1	3	5	8	1019.298
#432	CNOT7	3	7	10	747.485
#433	ELK3	3	13	16	851.452
#434	NR4A3	3	6	9	760.222
#435	MEIS2	3	15	18	1340.748
#436	GTF2IRD1	3	3	6	12.66
#437	SCML1	3	6	9	829.795
#438	ZNF174	3	7	10	232.69
#439	SP140	3	13	16	907.318
#440	ZNF215	3	7	10	451.66
#441	BRD8	3	10	13	398.84
#442	IRF6	3	7	10	192.63
#443	TFDP1	3	11	14	952.407
#444	GATAD1	3	10	13	816.211
#445	CREB5	3	6	9	378.691
#446	RUNX3	3	10	13	294.948
#447	RBCK1	3	10	13	1320.422
#448	PAX6	3	8	11	2208.338
#449	ZNF167	3	8	11	543.381
#450	CSDA	3	15	18	1273.188
#451	POU6F1	3	5	8	182.674
#452	ZNF134	2	5	7	546.692
#453	LZTS1	2	7	9	344.296
#454	ZNF277	2	14	16	432.374
#455	EGR2	2	10	12	599.069
#456	NFIB	2	7	9	975.631
#457	MYBL2	2	11	13	645.859
#458	MSL3	2	11	13	637.403
#459	JUNB	2	16	18	1487.483
#460	HHEX	2	7	9	598.479
#461	BTG2	2	14	16	946.761
#462	ATF5	2	12	14	741.854
#463	TGIF1	2	12	14	246.206
#464	NFYA	2	7	9	292.317
#465	SPIB	2	9	11	1242.232
#466	SOX11	2	5	7	446.508
#467	ZNF268	2	6	8	296.544
#468	HOXB2	2	7	9	598.386
#469	AFF1	2	13	15	1170.428
#470	PLAG1	2	12	14	738.445
#471	ELF4	2	9	11	216.455
#472	GATAD2A	2	7	9	130.953
#473	PPARD	2	6	8	300.427
#474	MYF6	2	11	13	846.11
#475	MBD1	2	12	14	383.813
#476	ERF	2	6	8	324.82
#477	PPARA	2	7	9	248.211
#478	ESR2	2	9	11	531.65
#479	ONECUT2	1	9	10	25.982
#480	GTF2H3	1	10	11	103.141
#481	SRF	1	9	10	750.944
#482	SMAD1	1	12	13	135.717
#483	TAF10	1	9	10	199.026
#484	IKZF3	1	9	10	122.756
#485	STAT5B	1	7	8	141.349
#486	CTBP1	1	8	9	141.142
#487	PRRX1	1	5	6	15.224
#488	ZNF207	1	9	10	259.166
#489	STAT6	1	7	8	122.844
#490	SOX12	1	10	11	1143.499
#491	BCL6	1	14	15	1223.998
#492	LEF1	1	10	11	251.135
#493	DRAP1	1	10	11	635.956
#494	DBP	0	7	7	0
#495	CTNNB1	0	13	13	0
#496	MYCN	0	5	5	0
#497	MSRB2	0	9	9	0
#498	SOX4	0	17	17	0
#499	TCF7	0	9	9	0
#500	HMBOX1	0	6	6	0