Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	YBX1	59	6	65	245.954
#2	MAF	58	3	61	127.271
#3	TCF4	57	0	57	0
#4	ZNF207	50	1	51	55.103
#5	ZEB1	50	6	56	213.104
#6	ELK3	50	3	53	58.916
#7	NR3C1	49	5	54	365.989
#8	E2F5	47	3	50	122.201
#9	EPAS1	45	10	55	3208.61
#10	MLL	43	4	47	863.228
#11	FOXM1	41	9	50	1146.208
#12	THRB	40	5	45	346.505
#13	XBP1	38	6	44	1348.299
#14	TSC22D3	37	8	45	1859.086
#15	FOXA1	37	8	45	1175.735
#16	HMG20B	37	15	52	6143.594
#17	ADNP	36	4	40	669.009
#18	ERG	35	6	41	1665.033
#19	HOXD4	34	10	44	2800.623
#20	CREBZF	34	12	46	975.225
#21	NFYA	34	7	41	403.999
#22	BRD8	33	8	41	1324.29
#23	SMAD2	33	4	37	224.387
#24	GAS7	33	9	42	370.328
#25	FOXC1	33	7	40	1644.263
#26	MZF1	32	6	38	192.866
#27	GATA3	32	9	41	1447.186
#28	AR	31	8	39	667.726
#29	ESR1	31	6	37	1048.899
#30	HOXA5	30	10	40	532.769
#31	HMX1	30	4	34	308.126
#32	MEIS2	30	10	40	328.316
#33	ZNF3	30	16	46	2563.284
#34	POU3F4	29	6	35	516.665
#35	TFDP1	29	10	39	593.787
#36	ZSCAN5A	29	1	30	7.184
#37	TBX5	28	1	29	35.278
#38	SNAI2	28	5	33	251.921
#39	RCOR1	28	6	34	1077.483
#40	LASS6	28	8	36	915.391
#41	RELA	28	6	34	661.473
#42	ATF1	27	6	33	476.085
#43	PAX8	27	4	31	44.482
#44	RFX5	27	12	39	3457.218
#45	ZNF131	27	11	38	767.86
#46	TFDP3	26	9	35	321.218
#47	BCL6	26	14	40	2162.49
#48	FOXN3	26	14	40	953.084
#49	FOXE1	26	7	33	97.805
#50	TRIM22	25	9	34	1194.202
#51	FOXA2	25	4	29	1021.783
#52	SIM1	25	5	30	232.669
#53	AEBP1	25	12	37	448.28
#54	CTBP1	25	14	39	1445.516
#55	BACH1	25	9	34	1935.132
#56	TCFL5	25	9	34	2636.134
#57	IRF3	24	12	36	697.661
#58	NFE2L3	24	12	36	915.455
#59	DLX2	24	2	26	125.458
#60	GATAD2A	24	6	30	296.147
#61	PAX6	24	12	36	550.863
#62	HCLS1	24	9	33	421.334
#63	HOXA6	24	6	30	153.412
#64	NFYB	24	11	35	558.529
#65	IRF2	24	13	37	1473.593
#66	GTF2H3	23	1	24	25.197
#67	NFYC	23	13	36	633.73
#68	MSL3	23	8	31	1834.09
#69	MSX2	23	8	31	494.745
#70	DRAP1	23	15	38	931.648
#71	CREBL2	23	9	32	1029.378
#72	MTA1	23	12	35	1987.165
#73	LMO4	23	12	35	1674.171
#74	FLI1	23	2	25	1310.713
#75	CNBP	23	10	33	3459.323
#76	MYC	23	11	34	1214.846
#77	KLF11	22	12	34	2486.261
#78	MBD1	22	4	26	209.227
#79	NR6A1	22	5	27	89.06
#80	MEOX2	22	12	34	2032.924
#81	KLF10	22	8	30	359.773
#82	TCF7L2	22	17	39	2830.485
#83	ZFPM2	22	8	30	2666.89
#84	NFIL3	22	10	32	390.53
#85	HDAC2	22	12	34	5479.015
#86	SPDEF	21	9	30	1148.298
#87	RBPJ	21	11	32	3673.757
#88	RARB	21	4	25	78.167
#89	CBFA2T3	21	7	28	386.176
#90	MEF2C	21	7	28	140.811
#91	RUNX3	21	15	36	1170.082
#92	SCAND1	21	13	34	1711.333
#93	SMAD4	21	7	28	121.857
#94	NFATC1	20	12	32	3678.442
#95	YEATS4	20	13	33	2077.143
#96	TCF12	20	10	30	1782.851
#97	IRF1	20	9	29	2607.08
#98	KLF5	20	16	36	3705.926
#99	NFAT5	20	11	31	594.161
#100	ARNTL2	20	9	29	629.491
#101	SPEN	20	5	25	116.805
#102	BACH2	20	10	30	747.654
#103	GRHL2	20	13	33	793.33
#104	TFE3	20	13	33	1791.757
#105	SLC30A9	20	13	33	5019.076
#106	CREBBP	20	10	30	1359.719
#107	PTTG1	20	6	26	854.394
#108	ATF2	19	7	26	276.556
#109	ELK1	19	5	24	308.523
#110	CSDA	19	17	36	1719.147
#111	BATF	19	10	29	359.733
#112	FEV	19	9	28	457.345
#113	HOXD1	19	11	30	687.962
#114	SNAPC5	19	11	30	574.836
#115	ZHX3	19	15	34	1712.515
#116	SMAD6	19	8	27	440.083
#117	TFAP2A	19	12	31	686.028
#118	NFIB	19	11	30	823.642
#119	HIC1	19	7	26	229.523
#120	E2F2	18	9	27	2865.37
#121	ZNF83	18	15	33	2527.975
#122	HDAC1	18	15	33	1401.115
#123	NKX6-1	18	5	23	83.457
#124	KDM5A	18	13	31	1830.851
#125	SOX10	18	17	35	1391.591
#126	NR2E1	18	5	23	96.695
#127	NR3C2	18	12	30	607.69
#128	GATA2	18	17	35	2026.388
#129	PKNOX2	18	6	24	55.751
#130	AFF1	18	14	32	1499.809
#131	ZNF24	18	16	34	1904.774
#132	NR1I2	18	6	24	204.188
#133	PKNOX1	18	10	28	1129.567
#134	ZFP36L1	18	14	32	2685.986
#135	TFAM	18	10	28	525.333
#136	CREB1	17	10	27	184.596
#137	ETV7	17	9	26	278.598
#138	MNX1	17	2	19	9.573
#139	MAFG	17	11	28	1433.035
#140	MEOX1	17	11	28	1003.957
#141	ZFP37	17	15	32	2307.591
#142	RERE	17	15	32	629.416
#143	TAF5	17	12	29	4564.657
#144	CREB3	17	9	26	799.048
#145	TARDBP	17	16	33	4256.343
#146	E2F3	17	14	31	2316.984
#147	ENO1	17	14	31	852.035
#148	SREBF2	17	16	33	1498.442
#149	ZEB2	17	10	27	1046.127
#150	PHOX2A	17	8	25	342.113
#151	BHLHE40	17	19	36	1651.043
#152	HIF3A	17	7	24	284.979
#153	HOXA9	17	10	27	4462.26
#154	CEBPB	16	14	30	1433.677
#155	NR4A1	16	10	26	1294.161
#156	EN2	16	12	28	1190.447
#157	ELK4	16	6	22	101.412
#158	PPARG	16	6	22	146.245
#159	REST	16	14	30	509.123
#160	ARID4A	16	11	27	1907.015
#161	CBFB	16	15	31	3303.611
#162	E4F1	16	13	29	935.959
#163	MEIS3P1	16	20	36	2309.833
#164	CSRNP3	16	20	36	1435.756
#165	DMTF1	16	10	26	486.292
#166	HMGB2	16	17	33	868.712
#167	ELF5	16	12	28	598.777
#168	SPIB	16	18	34	1898.377
#169	LASS2	16	15	31	1807.558
#170	CUX2	16	3	19	36.663
#171	SATB1	15	18	33	3758.316
#172	KLF9	15	13	28	820.073
#173	TCEAL1	15	16	31	2170.688
#174	FOXO1	15	15	30	1099.228
#175	BCL3	15	19	34	2364.47
#176	SOX13	15	11	26	2960.622
#177	IRF5	15	20	35	4875.166
#178	ZBTB17	15	9	24	686.464
#179	TBR1	15	9	24	178.45
#180	TP63	15	14	29	1900.669
#181	KLF2	14	20	34	1391.664
#182	MLLT10	14	16	30	1844.744
#183	PEG3	14	26	40	7483.663
#184	GATA1	14	9	23	810.687
#185	GSC2	14	6	20	282.457
#186	ETV2	14	7	21	254.818
#187	MAFB	14	14	28	1038.539
#188	NFATC3	14	10	24	278.455
#189	TEAD1	14	9	23	1680.84
#190	HCFC1	14	22	36	3821.293
#191	ZKSCAN5	14	9	23	190.398
#192	RARG	14	5	19	575.025
#193	NR2C1	14	16	30	2388.716
#194	ZNF155	14	10	24	83.89
#195	RFXANK	14	14	28	621.241
#196	ZNF133	14	16	30	2487.751
#197	ZNF193	14	20	34	2095.074
#198	MYBL2	14	16	30	1551.934
#199	PRDM2	14	10	24	647.13
#200	TRIM28	14	12	26	1444.287
#201	ZNF639	14	17	31	1966.232
#202	FOXK2	13	14	27	3972.219
#203	HOXB6	13	7	20	2721.582
#204	UBN1	13	18	31	2307.706
#205	TFEC	13	9	22	561.246
#206	ATF3	13	14	27	1357.457
#207	ELF3	13	13	26	2653.192
#208	ZNF219	13	13	26	421.727
#209	NCOR1	13	14	27	2551.596
#210	TEAD4	13	13	26	792.969
#211	MECOM	13	12	25	328.76
#212	ZNF134	13	14	27	2705.063
#213	TP73	13	13	26	2743.598
#214	PLSCR1	13	15	28	645.372
#215	ZSCAN16	13	13	26	3781.403
#216	SOX11	13	19	32	1316.881
#217	ETV1	13	18	31	555.46
#218	MYT1L	13	5	18	151.548
#219	RB1	13	13	26	2334.539
#220	SIX3	13	5	18	309.502
#221	PAX7	13	8	21	980.529
#222	SLC2A4RG	12	12	24	1931.963
#223	IRF8	12	8	20	499.903
#224	ADNP2	12	13	25	549.341
#225	PBX1	12	17	29	1263.446
#226	NR5A2	12	8	20	483.817
#227	CDKN2A	12	14	26	4879.057
#228	TBX10	12	16	28	1823.913
#229	RUNX1	12	13	25	1631.238
#230	BLZF1	12	17	29	1867.124
#231	ZSCAN18	12	16	28	1789.713
#232	ETV6	12	18	30	709.424
#233	CBFA2T2	12	8	20	300.069
#234	SMAD5	12	11	23	692.9
#235	VDR	12	14	26	1145.736
#236	HLF	12	15	27	4387.372
#237	ZIC1	12	20	32	847.15
#238	ZKSCAN1	12	8	20	2618.961
#239	NR4A3	12	19	31	1908.845
#240	ZNF217	12	7	19	458.69
#241	NOTCH1	11	20	31	1528.549
#242	ZNF165	11	21	32	4486.365
#243	RXRB	11	14	25	1179.345
#244	HOXB2	11	8	19	1131.47
#245	ZFP36L2	11	21	32	1526.566
#246	MYT1	11	21	32	3282.966
#247	SOX4	11	13	24	854.976
#248	HOXA10	11	14	25	528.459
#249	EGR2	11	21	32	2528.441
#250	IRX5	11	22	33	1404.438
#251	EVX1	11	13	24	657.053
#252	HOXA1	11	15	26	1389.023
#253	PITX1	11	19	30	1769.567
#254	TBX1	11	9	20	2023.668
#255	RXRA	11	14	25	476.16
#256	MITF	11	9	20	182.122
#257	NKX2-1	11	13	24	1503.747
#258	ZNF45	11	16	27	1356.249
#259	NR5A1	11	15	26	1332.372
#260	ZNF93	11	12	23	1028.888
#261	RFX3	11	12	23	737.695
#262	TGIF1	11	17	28	1472.618
#263	SP140	11	6	17	338.158
#264	FOXN1	11	11	22	1438.893
#265	GCFC1	11	14	25	426.853
#266	CUX1	11	16	27	1548.78
#267	TRIM29	10	14	24	1942.368
#268	TCF7L1	10	11	21	277.87
#269	TADA2A	10	15	25	2529.806
#270	NFX1	10	9	19	336.424
#271	TGIF2	10	12	22	155.432
#272	SATB2	10	10	20	1158.64
#273	ARID3A	10	16	26	2178.573
#274	SOX12	10	12	22	1276.201
#275	ATF6	10	15	25	874.874
#276	ELF4	10	18	28	2923.274
#277	EN1	10	17	27	1223.54
#278	IRF9	10	15	25	594.113
#279	HEY1	10	18	28	1651.751
#280	NOLC1	10	13	23	3493.793
#281	ERF	10	12	22	873.365
#282	TWIST1	10	14	24	141.385
#283	NR2F6	10	20	30	3977.262
#284	JUN	10	13	23	915.26
#285	JUNB	10	18	28	697.001
#286	TCF7	10	13	23	447.884
#287	ZNF277	10	15	25	2264.773
#288	LHX2	10	14	24	701.711
#289	PLAG1	10	25	35	2169.89
#290	GCM1	9	8	17	109.223
#291	SCML1	9	16	25	1516.7
#292	HOXC8	9	6	15	87.635
#293	DLX6	9	15	24	346.968
#294	BCL11B	9	17	26	1690.199
#295	HMGA1	9	16	25	1155.088
#296	SOX18	9	13	22	2536.862
#297	CEBPD	9	18	27	1627.024
#298	MGA	9	20	29	3891.203
#299	E2F4	9	18	27	1865.536
#300	HES1	9	14	23	1365.766
#301	TAF1B	9	21	30	1959.142
#302	BHLHE41	9	16	25	1445.454
#303	HSF1	9	13	22	903.195
#304	ZNF135	9	12	21	1074.386
#305	CNOT8	9	16	25	1253.795
#306	ZNF154	9	12	21	1198.349
#307	FOXL1	9	11	20	403.352
#308	FOXO4	9	10	19	2325.964
#309	SMAD3	9	16	25	638.934
#310	TAF4	9	15	24	2107.104
#311	ETV5	9	15	24	1261.864
#312	KLF6	9	21	30	716.261
#313	THRA	9	20	29	1607.811
#314	HSF2	9	14	23	2073.774
#315	FOXG1	9	19	28	1970.545
#316	FUBP1	9	21	30	753.088
#317	RCAN1	9	17	26	1016.885
#318	GBX2	9	10	19	504.197
#319	TFCP2L1	9	13	22	763.045
#320	MYOG	8	5	13	155.769
#321	REL	8	16	24	1442.591
#322	MYCL1	8	10	18	446.452
#323	BUD31	8	13	21	1394.466
#324	NFE2L1	8	14	22	989.64
#325	CREB5	8	23	31	1048.058
#326	HOXD9	8	15	23	306.589
#327	CREM	8	22	30	1019.656
#328	TFAP2C	8	13	21	1198.076
#329	TFAP2B	8	25	33	1252.023
#330	MAFF	8	12	20	576.316
#331	POU2F2	8	16	24	2152.647
#332	RUNX1T1	8	21	29	657.556
#333	CITED2	8	18	26	1358.514
#334	STAT3	8	12	20	1358.335
#335	SLC26A3	8	19	27	3097.485
#336	AHR	8	19	27	1655.19
#337	LHX1	8	6	14	43.35
#338	TSC22D2	8	13	21	1199.847
#339	PCGF2	8	19	27	3013.983
#340	SCML2	8	14	22	732.211
#341	MEIS1	8	26	34	2810.441
#342	TCF3	8	23	31	1202.262
#343	DBP	8	11	19	660.721
#344	GATAD1	8	8	16	600.132
#345	SOX9	8	19	27	1389.276
#346	HOXC10	8	16	24	1149.084
#347	HOXB7	8	8	16	492.282
#348	MNT	8	16	24	796.733
#349	PBX3	7	16	23	706.176
#350	MAX	7	9	16	320.802
#351	ELF1	7	19	26	1246.129
#352	SUPT6H	7	20	27	980.612
#353	HOXD13	7	15	22	127.413
#354	ZSCAN12	7	11	18	239.753
#355	KLF7	7	14	21	155.35
#356	TULP4	7	11	18	555.981
#357	ST18	7	16	23	1228.241
#358	FBXW7	7	17	24	1449.547
#359	ONECUT1	7	21	28	859.117
#360	GTF2H4	7	17	24	803.007
#361	SIM2	7	21	28	1168.592
#362	TCF20	7	16	23	469.847
#363	NFATC4	7	19	26	1011.484
#364	SNAPC4	7	15	22	1366.689
#365	KLF12	7	12	19	665.066
#366	CEBPA	7	21	28	1403.575
#367	HNF1B	7	17	24	472.536
#368	TRPS1	7	19	26	678.896
#369	IRF7	7	12	19	401.173
#370	SRF	7	9	16	294.313
#371	SOX30	7	18	25	850.884
#372	BNC1	7	14	21	229.478
#373	ESRRA	7	12	19	941.162
#374	SREBF1	6	18	24	872.62
#375	ISL1	6	19	25	782.108
#376	TADA3	6	12	18	664.151
#377	HNF4G	6	19	25	1892.194
#378	ZNF175	6	9	15	273.094
#379	NFIX	6	15	21	819.951
#380	FOXC2	6	14	20	596.558
#381	SALL1	6	15	21	794.329
#382	RFX1	6	13	19	606.019
#383	POU4F3	6	11	17	841.894
#384	KLF3	6	11	17	388.699
#385	PA2G4	6	13	19	390.412
#386	FOXO3	6	17	23	1018.381
#387	FOS	6	19	25	803.48
#388	AATF	6	15	21	776.134
#389	FOXI1	6	17	23	739.103
#390	HOXC4	6	12	18	1588.252
#391	HOXD12	6	18	24	2326.317
#392	MEF2A	6	20	26	3190.664
#393	SOX5	6	11	17	656.763
#394	HOXD3	6	12	18	163.23
#395	OLIG2	6	8	14	114.733
#396	MMP14	6	22	28	715.362
#397	NR2F2	6	22	28	1384.143
#398	ZNF132	6	9	15	177.291
#399	NKX3-1	6	15	21	527.122
#400	NKX3-2	5	22	27	1061.058
#401	STAT1	5	12	17	368.379
#402	PGR	5	14	19	694.796
#403	EDF1	5	16	21	321.513
#404	ATOH1	5	12	17	852.78
#405	STAT5A	5	19	24	795.121
#406	POU4F1	5	22	27	799.858
#407	RBCK1	5	18	23	989.206
#408	GABPA	5	16	21	626.615
#409	TCF15	5	17	22	1357.294
#410	DMRT1	5	14	19	335.63
#411	ZNF238	5	21	26	1231.246
#412	FOSB	5	18	23	3695.825
#413	RNF4	5	19	24	678.166
#414	HOXB5	5	13	18	2427.321
#415	MYCN	5	27	32	934.583
#416	ZNF85	5	13	18	570.703
#417	ZNF268	5	21	26	1697.104
#418	PITX3	5	13	18	2313.469
#419	TBX3	5	30	35	1198.007
#420	LEF1	5	5	10	212.617
#421	HOPX	5	16	21	1286.635
#422	IRF6	5	15	20	739.548
#423	ZSCAN2	5	8	13	148.982
#424	GATA6	5	17	22	1271.604
#425	SUPT4H1	5	16	21	777.797
#426	TAL1	5	23	28	1670.531
#427	ARNT2	5	25	30	1413.884
#428	ZNF91	5	16	21	392.088
#429	WNT5A	5	14	19	912.06
#430	IKZF1	5	16	21	2290.084
#431	SOX2	4	12	16	983.992
#432	IRF4	4	10	14	582.685
#433	SPI1	4	16	20	647.907
#434	MYF6	4	16	20	892.911
#435	MSRB2	4	14	18	245.22
#436	HHEX	4	21	25	463.07
#437	CREB3L1	4	18	22	1228.849
#438	E2F8	4	13	17	1477.649
#439	NKX2-8	4	12	16	1510.829
#440	HR	4	20	24	1598.097
#441	NR1D2	4	18	22	357.951
#442	EHF	4	17	21	367.784
#443	ESRRG	4	15	19	1236.484
#444	ZFHX3	4	13	17	510.988
#445	SCAND2	4	15	19	648.853
#446	FOXJ1	4	11	15	263.096
#447	MLX	4	12	16	168.426
#448	HIRA	4	15	19	240.177
#449	TBX6	3	16	19	152.812
#450	C11orf9	3	15	18	593.917
#451	TLX2	3	16	19	305.297
#452	HOXA7	3	18	21	1233.29
#453	ASCL2	3	16	19	265.701
#454	KDM5B	3	20	23	1362.247
#455	HMBOX1	3	15	18	117.521
#456	SHOX	3	14	17	483.121
#457	ETS1	3	19	22	219.637
#458	HNF4A	3	25	28	1090.228
#459	PBX2	3	13	16	669.924
#460	SIX5	3	12	15	151.913
#461	NR2F1	3	19	22	71.625
#462	EGR1	3	19	22	2213.123
#463	CITED1	3	30	33	1503.227
#464	RUNX2	3	11	14	65.735
#465	NPAS2	3	22	25	306.013
#466	NR4A2	3	26	29	827.208
#467	RARA	3	20	23	677.555
#468	SMAD1	3	15	18	220.891
#469	KLF4	3	20	23	240.738
#470	NFKB2	3	18	21	742.704
#471	ATF5	3	23	26	325.478
#472	FOXE3	3	18	21	163.841
#473	TCF25	3	21	24	896.106
#474	HAND2	2	14	16	427.682
#475	E2F6	2	14	16	225.07
#476	POU3F1	2	16	18	336.209
#477	ZHX2	2	24	26	552.078
#478	LZTS1	2	11	13	164.851
#479	ASCL1	2	19	21	415.456
#480	HOXB13	2	22	24	323.967
#481	EGR3	2	26	28	378.239
#482	HOXB3	2	26	28	684.415
#483	SOX1	2	18	20	137.948
#484	ZNF140	2	9	11	250.17
#485	WT1	2	24	26	456.271
#486	FOXB1	2	24	26	779.421
#487	EGR4	2	14	16	221.253
#488	SIX1	2	26	28	545.844
#489	POU2F3	2	22	24	278.277
#490	HOXB8	2	12	14	82.785
#491	SOLH	2	23	25	246.953
#492	ESR2	2	19	21	471.391
#493	IRX4	2	25	27	1738.081
#494	TP53	1	16	17	371.821
#495	ZNF174	1	22	23	67.946
#496	ZNF80	1	12	13	465.456
#497	MEF2D	1	23	24	373.73
#498	HOXD10	1	11	12	167.849
#499	TFEB	0	13	13	0
#500	HEY2	0	23	23	0