Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZNF207	38	3	41	455.568
#2	PBX1	37	6	43	1150.544
#3	OVOL1	36	9	45	1666.596
#4	HHEX	36	6	42	772.521
#5	CREB1	35	3	38	294.238
#6	CREBL2	35	8	43	2395.536
#7	SUPT6H	35	8	43	1384.041
#8	ZNF500	33	8	41	1508.367
#9	UBN1	32	7	39	648.393
#10	MLL	32	6	38	498.667
#11	ESRRA	32	5	37	946.35
#12	FOXE1	31	11	42	2266.541
#13	LMO4	31	9	40	1165.408
#14	IRF8	30	2	32	537.653
#15	SOX4	30	15	45	2344.754
#16	SNAI2	30	6	36	1000.796
#17	PPARD	30	8	38	618.483
#18	RERE	30	10	40	1506.151
#19	REST	29	4	33	165.857
#20	CBFB	29	3	32	435.035
#21	VDR	29	10	39	883.236
#22	FLI1	28	3	31	513.545
#23	FOSL2	28	11	39	1908.43
#24	MEF2C	28	3	31	153.636
#25	MYOG	27	5	32	114.101
#26	RARB	27	9	36	1671.692
#27	TRIM29	27	7	34	971.764
#28	IRF2	27	7	34	372.765
#29	ATF1	26	8	34	1043.873
#30	SOX12	26	11	37	2292.877
#31	RUNX1	26	10	36	1089.562
#32	ZNF3	26	10	36	1527.561
#33	FUBP1	26	6	32	708.924
#34	PITX1	26	13	39	2632.269
#35	FOXO4	26	3	29	160.556
#36	CNOT8	26	13	39	2113.462
#37	HOPX	25	14	39	3140.78
#38	MLX	25	7	32	438.071
#39	TCF12	25	10	35	1532.077
#40	HMX1	25	2	27	37.465
#41	GAS7	25	8	33	1174.432
#42	MAX	25	11	36	868.667
#43	SOX2	24	9	33	1048.66
#44	SUPT4H1	24	6	30	1084.759
#45	SNAPC2	24	1	25	37.949
#46	HSF2	24	9	33	1499.15
#47	TFAP2C	24	13	37	1298.246
#48	ZEB1	24	4	28	246.052
#49	ZNF238	24	12	36	1111.674
#50	GABPB1	23	4	27	188.203
#51	FOS	23	7	30	1055.09
#52	ZSCAN16	23	11	34	1140.592
#53	ENO1	23	2	25	283.651
#54	KLF5	23	11	34	1863.847
#55	AEBP1	23	5	28	647.473
#56	YBX1	23	8	31	803.296
#57	KLF3	23	6	29	633.97
#58	PA2G4	23	11	34	1458.572
#59	SREBF1	23	11	34	1389.785
#60	DRAP1	22	11	33	1294.61
#61	HES1	22	12	34	1727.12
#62	TEAD4	22	12	34	1718.836
#63	IKZF1	22	5	27	629.577
#64	SMAD4	22	10	32	1224.37
#65	FOXM1	22	8	30	1171.85
#66	SOX15	22	2	24	31.524
#67	ECSIT	22	17	39	2566.567
#68	KDM5A	22	6	28	1460.504
#69	MEIS1	22	8	30	642.989
#70	HOXA10	21	13	34	1350.633
#71	KLF10	21	8	29	460.127
#72	MAF	21	16	37	2388.096
#73	ATF2	21	8	29	1450.533
#74	NOLC1	21	11	32	693.91
#75	LZTR1	21	14	35	1463.029
#76	ETS2	21	12	33	1203.517
#77	JUND	21	12	33	880.882
#78	VAV1	21	5	26	453.596
#79	JUNB	21	9	30	889.18
#80	RUNX3	20	16	36	1692.244
#81	RFX5	20	15	35	2043.809
#82	MTF1	20	16	36	1363.566
#83	POU3F1	20	8	28	737.39
#84	ALS2CR8	20	13	33	2213.495
#85	AFF4	20	5	25	482.118
#86	SMAD1	20	11	31	963.552
#87	ETV5	20	12	32	1315.185
#88	HMGB2	20	12	32	1099.354
#89	MYNN	20	6	26	511.045
#90	HEY1	20	12	32	1302.152
#91	TWIST1	20	10	30	612.876
#92	E4F1	20	12	32	1547.386
#93	KLF7	20	9	29	1210.681
#94	TCF15	20	6	26	157.653
#95	FOXF1	19	10	29	660.289
#96	TFEC	19	7	26	543.561
#97	ZKSCAN5	19	8	27	795.719
#98	TCF4	19	7	26	599.775
#99	ZEB2	19	5	24	244.44
#100	LEF1	19	16	35	1510.311
#101	PAX6	19	16	35	1425.477
#102	MXD1	19	9	28	731.103
#103	KLF6	19	7	26	922.593
#104	ETV4	19	11	30	1988.575
#105	RBPJ	19	14	33	1269.438
#106	RARG	19	10	29	1921.505
#107	GTF2H3	19	15	34	1371.827
#108	KLF2	19	12	31	1918.669
#109	MZF1	19	7	26	652.021
#110	ELF3	19	12	31	951.896
#111	ZNF174	18	8	26	959.995
#112	TRIM22	18	7	25	739.913
#113	ZSCAN18	18	17	35	1806.63
#114	ARNTL2	18	15	33	1490.215
#115	SPEN	18	5	23	906.858
#116	ZFP36L2	18	10	28	1373.266
#117	BTG2	18	13	31	1769.768
#118	NFYB	18	9	27	832.313
#119	ZNF148	18	11	29	1285.909
#120	TFDP1	18	9	27	526.421
#121	BUD31	18	12	30	752.722
#122	NFE2L2	18	12	30	1431.181
#123	GTF2I	18	8	26	329.1
#124	SOX13	18	13	31	1211.934
#125	TEAD3	18	11	29	1607.213
#126	GABPA	18	11	29	463.732
#127	SCAND1	18	18	36	1522.573
#128	KLF12	18	8	26	643.055
#129	PHTF1	18	4	22	337.186
#130	NFATC4	18	14	32	1318.445
#131	ZNF75D	18	12	30	1365.041
#132	EVX1	18	5	23	68.894
#133	SP3	18	7	25	318.877
#134	FOXJ2	17	8	25	1005.423
#135	HCLS1	17	9	26	1496.016
#136	CEBPA	17	11	28	563.225
#137	ZNF217	17	14	31	1804.228
#138	FOSL1	17	17	34	1381.3
#139	PRRX1	17	16	33	989.384
#140	GTF2IRD1	17	9	26	575.596
#141	TAF4	17	14	31	1876.093
#142	ZNF643	17	8	25	608.333
#143	MYBL2	17	8	25	1354.661
#144	ZNF85	17	8	25	451.289
#145	NR3C1	17	16	33	1609.938
#146	NFIC	17	9	26	754.091
#147	TARDBP	17	14	31	1312.323
#148	SCMH1	17	14	31	1304.372
#149	SPIB	16	7	23	940.657
#150	DLX2	16	18	34	2446.286
#151	DMTF1	16	9	25	1295.258
#152	KLF4	16	13	29	1188.224
#153	MTA1	16	14	30	1198.033
#154	TP63	16	11	27	837.453
#155	SP140	16	10	26	682.588
#156	BTAF1	16	12	28	1161.011
#157	POU2F1	16	15	31	1041.93
#158	NR2F2	16	10	26	1217.406
#159	ELF1	16	13	29	755.431
#160	ESRRG	16	7	23	1842.996
#161	ARID4A	16	9	25	1103.172
#162	TRIM28	16	17	33	2074.428
#163	IRF3	16	10	26	1151.459
#164	ATF4	16	11	27	982.172
#165	ETV1	16	17	33	2247.932
#166	SNAPC5	15	7	22	554.695
#167	GLI3	15	16	31	1601.535
#168	BRD8	15	7	22	521.834
#169	IRF9	15	12	27	1016.171
#170	TAF6	15	11	26	724.159
#171	HOXD3	15	8	23	1671.664
#172	RCOR1	15	12	27	1358.155
#173	STRN3	15	17	32	1932.945
#174	YEATS4	15	16	31	1634.831
#175	MAFB	15	18	33	1195.236
#176	NPAS2	15	17	32	2029.207
#177	CREB3L2	15	17	32	949.353
#178	RELA	15	10	25	1909.251
#179	MLXIPL	15	10	25	264.466
#180	SMAD5	15	12	27	612.679
#181	STAT4	15	6	21	105.159
#182	E2F3	15	14	29	1232.817
#183	AHCTF1	15	13	28	1582.037
#184	SIX1	15	17	32	1430.623
#185	MEF2D	15	8	23	229.463
#186	TFDP2	15	17	32	1297.787
#187	BNC1	15	10	25	534.872
#188	BACH2	15	13	28	1231.295
#189	NR4A2	15	20	35	2520.907
#190	NR2C1	15	13	28	2454.811
#191	MYCN	14	8	22	1023.615
#192	HOXC10	14	18	32	1978.845
#193	E2F5	14	16	30	790.499
#194	TSC22D1	14	10	24	2834.32
#195	CSDA	14	9	23	384.108
#196	RXRA	14	9	23	890.168
#197	HR	14	13	27	1157.862
#198	TCF25	14	9	23	811.912
#199	HNRNPAB	14	7	21	582.549
#200	TAF5	14	18	32	1758.184
#201	NFKB1	14	15	29	1248.154
#202	FOXA1	14	14	28	1617.121
#203	HOXC13	14	13	27	700.223
#204	AATF	14	10	24	854.777
#205	USF2	14	14	28	1678.697
#206	TCF20	13	8	21	605.626
#207	ERG	13	17	30	1821.497
#208	ARNT2	13	14	27	851.455
#209	MEIS2	13	18	31	997.165
#210	SPDEF	13	6	19	146.235
#211	PHF1	13	6	19	178.946
#212	HOXA9	13	17	30	777.183
#213	MAFF	13	12	25	1394.446
#214	ZFHX3	13	14	27	1433.357
#215	ZBTB38	13	10	23	597.42
#216	ZNF281	13	20	33	1219.798
#217	ETV7	13	18	31	1744.082
#218	ZSCAN5A	13	14	27	1335.84
#219	SCML2	13	8	21	633.975
#220	IRX5	13	12	25	967.495
#221	TFEB	13	18	31	1001.829
#222	FOXK2	13	18	31	1070.444
#223	ARNTL	13	10	23	435.877
#224	KLF11	13	11	24	977.038
#225	ZNF24	13	18	31	1944.779
#226	NFATC1	13	16	29	1205.554
#227	TGIF2	13	14	27	1081.294
#228	CNBP	13	12	25	642.557
#229	SLC2A4RG	13	16	29	1757.718
#230	EDF1	13	13	26	883.29
#231	GATA6	13	17	30	1421.665
#232	TSC22D4	13	8	21	148.167
#233	ZGPAT	13	10	23	681.142
#234	HOXD13	13	15	28	1706.44
#235	HMBOX1	13	14	27	1538.752
#236	HOXD11	12	14	26	1025.589
#237	PKNOX1	12	13	25	774.789
#238	ZNF232	12	16	28	968.332
#239	SMAD2	12	18	30	1908.577
#240	GLI2	12	14	26	1131.457
#241	PRDM2	12	10	22	1073.583
#242	NR4A3	12	16	28	1093.076
#243	NFATC3	12	18	30	1306.289
#244	C2orf3	12	18	30	1351.035
#245	PPARG	12	12	24	1046.721
#246	PURA	12	7	19	445.108
#247	KLF9	12	19	31	592.095
#248	ZNF187	12	11	23	646.807
#249	ELF4	12	12	24	873.939
#250	PRDM1	12	8	20	877.253
#251	ZNF140	12	13	25	1277.012
#252	HOXA4	12	16	28	1648.657
#253	XBP1	12	12	24	1173.104
#254	SATB1	12	19	31	1294.65
#255	RUNX1T1	12	16	28	1772.467
#256	IRF7	12	18	30	1462.114
#257	TBX2	12	13	25	1316.976
#258	ZNF93	12	10	22	811.791
#259	PRRX2	12	20	32	802.554
#260	NFKB2	12	10	22	1257.873
#261	STAT1	12	10	22	500.329
#262	HIF1A	12	14	26	931.354
#263	STAT6	12	8	20	654.74
#264	ATF3	12	14	26	1315.903
#265	IRX4	11	19	30	1495.56
#266	MSC	11	11	22	1282.366
#267	HLF	11	20	31	1802.317
#268	NFX1	11	12	23	935.919
#269	TCF3	11	22	33	2106.234
#270	FOXC1	11	17	28	1149.082
#271	PFDN1	11	13	24	1366.938
#272	HOXA1	11	19	30	900.934
#273	HMG20B	11	16	27	1097.721
#274	NR1H2	11	8	19	780.332
#275	SATB2	11	11	22	1066.389
#276	PEG3	11	10	21	1159.062
#277	ZNF219	11	16	27	1325.459
#278	YY1	11	12	23	996.697
#279	MGA	11	18	29	1267.925
#280	GCFC1	11	14	25	1444.31
#281	PCGF2	11	12	23	803.465
#282	NFAT5	11	6	17	566.403
#283	NFYA	11	17	28	1066.812
#284	MECOM	11	14	25	942.447
#285	ZNF394	11	8	19	624.955
#286	CREB3	11	12	23	674.41
#287	BLZF1	11	19	30	1023.153
#288	BCL3	11	12	23	889.427
#289	SOLH	11	12	23	766.161
#290	NR4A1	11	7	18	340.12
#291	TAF10	11	13	24	1218.141
#292	BACH1	11	17	28	1424.79
#293	IRF4	11	11	22	963.955
#294	PTTG1	11	12	23	605.509
#295	NR3C2	10	11	21	717.212
#296	BHLHE40	10	18	28	1073.093
#297	HOXA5	10	15	25	1103.718
#298	MSX2	10	12	22	653.949
#299	HMGA2	10	23	33	1605.019
#300	HMGB1	10	12	22	672.282
#301	NOTCH1	10	20	30	1386.612
#302	JUN	10	18	28	1252.408
#303	PBX3	10	14	24	1570.555
#304	TCF7	10	18	28	661.234
#305	SOX10	10	9	19	987.161
#306	CREBBP	10	14	24	1166.34
#307	NCOR1	10	13	23	1097.304
#308	IRF1	10	12	22	743.222
#309	FOXO3	10	12	22	662.285
#310	FOSB	10	7	17	370.651
#311	ZBTB48	10	12	22	475.802
#312	MSL3	10	10	20	278.442
#313	TFAM	10	13	23	721.846
#314	NPAT	10	13	23	519.933
#315	HOXD1	10	13	23	777.641
#316	CEBPB	10	21	31	941.361
#317	MLLT10	10	19	29	921.744
#318	NFYC	10	13	23	704.634
#319	MITF	10	17	27	1188.572
#320	MEIS3P1	9	16	25	1862.204
#321	TGIF1	9	26	35	1305.416
#322	MYC	9	19	28	756.253
#323	TCF7L2	9	19	28	1194.272
#324	CEBPD	9	15	24	561.127
#325	SIM2	9	10	19	787.189
#326	ZKSCAN1	9	10	19	695.019
#327	NFIL3	9	18	27	1310.15
#328	CREB3L1	9	8	17	645.639
#329	FOXD1	9	19	28	1753.474
#330	NR2E1	9	12	21	1272.566
#331	NFE2L1	9	13	22	535.543
#332	PBX2	9	18	27	1471.505
#333	MYCL1	9	20	29	1443.522
#334	NR1D2	9	20	29	1074.517
#335	HMGA1	9	21	30	774.844
#336	ZNF83	9	21	30	1205.233
#337	GRHL2	9	8	17	405.936
#338	MEF2A	9	16	25	1013.521
#339	ATF6	9	10	19	798.554
#340	ZNF189	9	16	25	1278.171
#341	DLX4	9	14	23	986.001
#342	ZNF202	9	15	24	875.022
#343	ELF2	9	12	21	431.005
#344	ZBTB17	9	19	28	1257.397
#345	SRF	9	14	23	689.596
#346	TCF7L1	9	15	24	807.588
#347	SMAD3	9	17	26	1441.418
#348	REL	8	19	27	1286.324
#349	DDIT3	8	14	22	755.749
#350	ADNP	8	12	20	564.336
#351	RFXANK	8	20	28	806.113
#352	FOXF2	8	20	28	1567.383
#353	CUX1	8	21	29	1068.501
#354	GATA3	8	22	30	1310.009
#355	AHR	8	18	26	1246.167
#356	CREBZF	8	13	21	484.906
#357	E2F6	8	16	24	570.561
#358	TFAP2A	8	19	27	2137.433
#359	BCL6	8	17	25	885.082
#360	TULP4	8	19	27	766.113
#361	TLX1	8	13	21	584.864
#362	FOXL2	8	10	18	403.318
#363	EPAS1	8	15	23	829.881
#364	ADNP2	8	13	21	917.292
#365	HOXB7	8	18	26	1025.934
#366	HDAC2	8	12	20	761.208
#367	TAF12	8	17	25	736.715
#368	GATAD2A	8	13	21	371.612
#369	ALX1	8	14	22	1104.791
#370	STAT3	8	21	29	878.761
#371	CBFA2T2	8	17	25	676.295
#372	SOX9	8	21	29	1793.333
#373	ZNF165	8	17	25	1765.559
#374	FOXG1	8	20	28	1011.737
#375	HSF1	8	18	26	754.708
#376	HOXD9	8	15	23	784.404
#377	HDAC1	7	16	23	476.414
#378	LHX2	7	14	21	442.381
#379	TCEAL1	7	12	19	700.286
#380	MEOX2	7	12	19	553.387
#381	SCML1	7	13	20	383.415
#382	HOXB6	7	12	19	831.97
#383	EGR3	7	14	21	1290.599
#384	GTF2H4	7	17	24	583.015
#385	ZNF277	7	18	25	745.096
#386	FOXN3	7	18	25	431.314
#387	MAFG	7	19	26	573.865
#388	CITED2	7	15	22	440.291
#389	ESR1	7	12	19	454.952
#390	IRF6	7	15	22	559.244
#391	TAF1B	7	13	20	731.44
#392	ZNF33B	7	13	20	532.104
#393	PLAG1	7	13	20	420.729
#394	ZXDC	7	22	29	1038.294
#395	CBFA2T3	7	16	23	941.252
#396	UBP1	7	17	24	1166.138
#397	RCAN1	7	19	26	520.394
#398	TAF7	7	17	24	755.391
#399	EHF	6	29	35	717.627
#400	TBX1	6	18	24	1730.804
#401	BATF	6	13	19	837.651
#402	MSX1	6	12	18	444.882
#403	NFE2L3	6	19	25	731.628
#404	PLAGL2	6	14	20	540.715
#405	LHX6	6	16	22	947.689
#406	SIX2	6	13	19	894.297
#407	WNT5A	6	10	16	354.483
#408	CREM	6	16	22	772.963
#409	KDM5B	6	16	22	526.815
#410	IRF5	6	10	16	457.433
#411	FBXW7	6	17	23	611.263
#412	SMAD6	6	11	17	629.27
#413	TADA3	6	18	24	824.703
#414	NR1H3	6	17	23	718.323
#415	BARX1	6	15	21	765.646
#416	EGR1	6	13	19	354.667
#417	NFIB	6	20	26	732.75
#418	ISL1	6	15	21	822.018
#419	HOXD4	6	11	17	869.567
#420	LASS2	6	17	23	618.576
#421	ZFHX4	6	14	20	540.266
#422	TFCP2L1	6	23	29	734.586
#423	MNT	6	14	20	934.183
#424	NR2F1	6	18	24	779.961
#425	CDKN2A	6	24	30	1546.423
#426	ZNF268	6	13	19	441.963
#427	TFE3	6	15	21	1108.305
#428	TSC22D3	6	19	25	535.35
#429	TBX3	6	18	24	513.655
#430	NR0B1	6	7	13	499.866
#431	TRPS1	6	20	26	1348.541
#432	ERF	6	13	19	580.99
#433	NR2F6	5	19	24	988.117
#434	BHLHE41	5	20	25	482.006
#435	SOX11	5	15	20	422.429
#436	RELB	5	15	20	371.4
#437	ZNF134	5	13	18	620.065
#438	ZNF91	5	17	22	356.945
#439	TP53	5	17	22	820.529
#440	CSRNP2	5	16	21	807.929
#441	RBCK1	5	14	19	442.125
#442	MMP14	5	15	20	335.64
#443	TAL1	5	14	19	713.184
#444	SREBF2	5	17	22	356.04
#445	E2F8	5	12	17	384.47
#446	ZNF434	5	18	23	960.618
#447	HEY2	5	16	21	401.414
#448	HMG20A	5	16	21	714.76
#449	MBD1	5	13	18	257.575
#450	PLSCR1	5	17	22	514.179
#451	LASS6	5	21	26	706.035
#452	CNOT7	5	16	21	1069.852
#453	FOXO1	5	19	24	827.389
#454	ZFPM2	5	16	21	1294.304
#455	MSRB2	5	13	18	371.396
#456	SALL2	4	13	17	286.463
#457	ZNF323	4	24	28	909.092
#458	CREB5	4	19	23	561.099
#459	POU2F3	4	13	17	167.233
#460	ZFP36L1	4	18	22	412.018
#461	SLC30A9	4	13	17	292.086
#462	TCFL5	4	25	29	790.051
#463	CTNNB1	4	14	18	868.818
#464	GATAD1	4	18	22	406.237
#465	ELF5	4	28	32	615.789
#466	EN1	4	20	24	727.909
#467	NKX3-1	4	19	23	1091.547
#468	C11orf9	4	15	19	972.106
#469	HOXD10	4	8	12	239.679
#470	ATF5	4	12	16	275.11
#471	EGR2	4	15	19	397.112
#472	RORA	4	19	23	786.747
#473	ZIC1	4	25	29	454.88
#474	ELK3	4	23	27	945.699
#475	TEAD1	4	11	15	351.032
#476	AFF1	3	12	15	157.107
#477	STAT2	3	17	20	680.824
#478	ZNF117	3	21	24	868.704
#479	HOXB2	3	21	24	936.042
#480	CIR1	3	16	19	430.579
#481	MEOX1	3	20	23	562.093
#482	HOXA7	3	18	21	569.401
#483	ZBTB25	3	18	21	373.141
#484	PITX2	3	14	17	529.713
#485	RB1	3	17	20	428.111
#486	ZHX2	3	15	18	325.905
#487	ZNF133	3	13	16	229.335
#488	TFCP2	3	16	19	310.981
#489	CLOCK	2	19	21	413.217
#490	CTBP1	2	14	16	327.903
#491	BCL11B	2	18	20	142.447
#492	ETV6	2	16	18	114.816
#493	ZNF131	2	15	17	279.718
#494	DBP	2	16	18	343.332
#495	ZNF274	2	11	13	255.206
#496	HIRA	2	15	17	126.706
#497	TSC22D2	2	23	25	433.469
#498	ZNF215	1	16	17	66.147
#499	ZNF45	1	18	19	116.246
#500	GATA2	1	14	15	97.592