Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NPAT	69	4	73	721.006
#2	FOXA1	66	2	68	1320.905
#3	HCLS1	65	3	68	167.499
#4	KLF1	60	3	63	74.5
#5	HAND1	56	5	61	1425.629
#6	NFYC	54	4	58	1169.087
#7	TAL1	54	3	57	403.482
#8	FLI1	54	2	56	1987.225
#9	SPDEF	52	4	56	188.074
#10	ESR1	50	8	58	323.413
#11	NFE2	49	5	54	225.271
#12	TFAM	49	10	59	905.006
#13	GATA3	48	7	55	300.503
#14	RFXANK	48	7	55	826.632
#15	ADNP2	46	9	55	621.481
#16	E4F1	45	8	53	922.171
#17	GABPA	44	10	54	1337.848
#18	SP4	43	9	52	1345.428
#19	MGA	43	10	53	320.634
#20	FOXC1	43	3	46	135.793
#21	AR	43	7	50	626.688
#22	XBP1	42	5	47	139.603
#23	ISL1	42	6	48	524.975
#24	HMGA2	41	8	49	969.576
#25	GLI2	39	9	48	545.868
#26	NFAT5	38	12	50	782.299
#27	RUNX3	37	7	44	316.781
#28	IRX5	37	8	45	266.978
#29	MYC	36	14	50	1859.14
#30	CSDA	36	13	49	624.605
#31	FUBP1	36	10	46	489.298
#32	HOXA11	36	13	49	944.236
#33	TSHZ2	36	18	54	2066.247
#34	MAX	36	9	45	623.936
#35	ZIC3	36	16	52	1661.049
#36	E2F3	36	9	45	1497.28
#37	EN1	35	11	46	345.86
#38	JUN	35	16	51	1342.86
#39	SNAI2	35	11	46	1957.889
#40	NFIL3	34	11	45	1102.214
#41	NFE2L1	34	12	46	689.999
#42	IRF8	34	2	36	30.061
#43	ZEB2	34	8	42	860.264
#44	SOX10	33	11	44	789.825
#45	NFATC3	33	7	40	638.774
#46	CTBP1	33	8	41	397.276
#47	ENO1	32	15	47	1114.126
#48	AHR	32	12	44	522.177
#49	ZNF446	32	11	43	678.382
#50	FOXM1	31	11	42	786.243
#51	ZGPAT	31	10	41	373.002
#52	HINFP	31	8	39	588.717
#53	TP53	31	13	44	851.938
#54	MYBL2	31	15	46	1861.101
#55	REXO4	31	14	45	1780.74
#56	HNF1B	30	9	39	424.058
#57	CDKN2A	30	11	41	1602.842
#58	MZF1	30	11	41	1387.182
#59	SMAD6	30	20	50	1292.27
#60	TADA3	30	16	46	948.442
#61	ELF5	30	9	39	759.763
#62	GTF2I	30	12	42	769.936
#63	TRIM22	30	4	34	57.617
#64	ESRRA	29	15	44	1154.701
#65	LASS6	29	10	39	437.434
#66	E2F1	29	12	41	1087.353
#67	MEF2C	29	13	42	913.025
#68	RBCK1	29	12	41	469.833
#69	ARNTL2	29	12	41	857.327
#70	CITED2	28	15	43	984.481
#71	ZNF140	28	14	42	1075.739
#72	ZNF83	28	15	43	1403.312
#73	TSC22D1	28	12	40	898.853
#74	SATB1	28	13	41	833.395
#75	SP1	28	17	45	1358.665
#76	HHEX	28	7	35	247.243
#77	E2F6	28	12	40	1135.381
#78	KLF6	27	19	46	1182.212
#79	MLL	27	13	40	2131.185
#80	CREB3L1	27	11	38	533.691
#81	USF2	26	14	40	887.622
#82	NR3C1	26	13	39	568.813
#83	TFAP2C	26	18	44	1250.664
#84	SOX4	25	16	41	872.882
#85	BACH1	25	10	35	1090.613
#86	CREBZF	25	15	40	595.029
#87	FOXC2	25	8	33	599.029
#88	MAFB	25	12	37	477.791
#89	GTF2H4	25	10	35	429.245
#90	HOXB2	25	16	41	653.084
#91	TAF12	25	23	48	2289.876
#92	HMGB2	25	12	37	504.06
#93	ELK3	24	18	42	2317.699
#94	ZNF91	24	8	32	429.36
#95	HES1	24	12	36	944.755
#96	SREBF1	24	12	36	1276.34
#97	GAS7	24	13	37	784.71
#98	NOTCH1	24	11	35	645.443
#99	TRIM29	24	10	34	264.706
#100	FOXO1	24	12	36	915.281
#101	ZFPM2	24	12	36	920.392
#102	TFDP2	24	14	38	1700.305
#103	ZNF45	23	18	41	1455.538
#104	SIX3	23	14	37	408.092
#105	TFDP3	23	11	34	745.655
#106	ZBTB48	23	21	44	1807.606
#107	NFYB	23	15	38	769.317
#108	SRF	23	16	39	2476.498
#109	TBX10	23	15	38	926.371
#110	RXRB	23	12	35	1222.317
#111	ZNF219	23	16	39	1215.835
#112	PEG3	23	16	39	1238.012
#113	GABPB1	23	12	35	549.663
#114	BNC1	23	15	38	1825.43
#115	MLXIPL	23	14	37	732.874
#116	ZNF165	23	17	40	543.476
#117	NR2E1	22	17	39	1004.784
#118	PDX1	22	16	38	1461.821
#119	JUND	22	18	40	1530.654
#120	SIX2	22	15	37	985.927
#121	HMGA1	22	18	40	585.582
#122	TFAP2A	22	24	46	1473.053
#123	VAX2	22	13	35	986.241
#124	BTG2	22	14	36	1098.228
#125	TCF7L2	22	18	40	1521.772
#126	E2F5	22	26	48	1966.335
#127	MTA2	21	15	36	1013.484
#128	PBX1	21	15	36	780.279
#129	ELF1	21	18	39	1129.708
#130	MYOD1	21	16	37	1559.112
#131	MYF6	21	16	37	1405.273
#132	CBFB	21	13	34	1201.211
#133	GATA1	21	24	45	1782.358
#134	TCFL5	21	11	32	333.894
#135	CREBBP	21	13	34	1020.317
#136	BHLHE40	21	15	36	906.058
#137	HOXD12	20	13	33	610.57
#138	MEIS2	20	18	38	1004.544
#139	SALL1	20	15	35	1578.684
#140	KLF9	20	18	38	1311.526
#141	HOXC10	20	24	44	1298.407
#142	SPIB	20	16	36	841.445
#143	ETS1	20	17	37	1319.596
#144	BLZF1	20	20	40	935.431
#145	NR4A3	20	15	35	1617.091
#146	BCL11B	20	10	30	452.499
#147	CSRNP3	20	17	37	1007.917
#148	NKX2-8	20	14	34	1253.746
#149	SLC26A3	20	23	43	893.567
#150	CITED1	19	16	35	984.675
#151	SNAPC4	19	24	43	1635.264
#152	TP73	19	10	29	1270.027
#153	FOXE1	19	20	39	1344.929
#154	PHOX2B	19	17	36	1179.68
#155	TLX1	19	12	31	351.618
#156	TSC22D4	19	12	31	699.064
#157	E2F2	19	19	38	1282.064
#158	STAT3	19	13	32	761.858
#159	HOXC8	19	18	37	1090.825
#160	PKNOX1	19	16	35	857.067
#161	MEIS3P1	19	13	32	686.233
#162	HIF3A	19	14	33	930.217
#163	GATA4	19	22	41	912.277
#164	ZFHX3	19	15	34	867.743
#165	ARNTL	19	15	34	1020.24
#166	MAFG	19	11	30	739.697
#167	TFEB	18	15	33	433.33
#168	NR2C2	18	17	35	902.243
#169	ATF3	18	13	31	747.801
#170	NR4A2	18	22	40	697.309
#171	ZXDC	18	19	37	618.76
#172	FOXF1	18	14	32	751.233
#173	ZNF444	18	14	32	773.378
#174	TBR1	18	16	34	1501.334
#175	LMO4	18	19	37	815.802
#176	PITX1	18	28	46	1096.013
#177	HIF1A	18	16	34	706.441
#178	MAFF	18	21	39	996.105
#179	ATF6	18	20	38	936.042
#180	TRPS1	18	21	39	1096.886
#181	SMAD3	18	18	36	982.028
#182	SIM2	18	21	39	1451.85
#183	ZFP36L2	17	15	32	490.273
#184	FOSL1	17	21	38	985.11
#185	ECSIT	17	18	35	868.631
#186	MSX2	17	24	41	1318.366
#187	AEBP1	17	16	33	682.547
#188	RERE	17	16	33	901.581
#189	NR1D2	17	16	33	655.747
#190	EPAS1	17	19	36	794.017
#191	ZNF41	17	22	39	3207.527
#192	NKX3-1	17	15	32	805.9
#193	HOXD9	17	21	38	1813.525
#194	NR1H4	17	15	32	1075.265
#195	HOXA7	17	19	36	785.692
#196	NR2F6	17	18	35	1120.309
#197	ZNF217	17	14	31	631.085
#198	HR	17	18	35	764.05
#199	TAF5	17	16	33	2362.547
#200	ELF4	17	20	37	958.79
#201	PPBPL2	16	23	39	1173.474
#202	HIC1	16	18	34	1218.298
#203	ZHX2	16	18	34	664.054
#204	NFKB2	16	20	36	806.252
#205	KLF2	16	15	31	849.596
#206	PKNOX2	16	17	33	1332.606
#207	POU2F2	16	20	36	1488.444
#208	SUPT6H	16	15	31	328
#209	ZNF174	16	20	36	736.097
#210	CBFA2T3	16	15	31	1001.062
#211	ZNF155	16	19	35	711.211
#212	ETV5	16	17	33	634.469
#213	ZSCAN16	16	13	29	877.001
#214	LEF1	16	21	37	1201.58
#215	IKZF3	16	24	40	1076.053
#216	TBX2	15	10	25	473.532
#217	HOXB9	15	15	30	1062.769
#218	KLF4	15	17	32	905.868
#219	C11orf9	15	19	34	621.833
#220	STRN3	15	16	31	487.081
#221	NFATC4	15	25	40	801.961
#222	RXRA	15	13	28	956.851
#223	BUD31	15	15	30	709.494
#224	TBX3	15	24	39	692.203
#225	MXD1	15	21	36	1175.987
#226	EGR3	15	16	31	492.643
#227	BCL6	15	17	32	753.61
#228	HSF1	15	18	33	903.481
#229	ATF5	15	21	36	1561.748
#230	PLSCR1	15	17	32	539.675
#231	SOX13	15	20	35	1636.696
#232	HNF4G	15	18	33	909.752
#233	RUNX1	15	15	30	641.281
#234	WT1	15	21	36	986.969
#235	HOXB8	15	18	33	1144.217
#236	HOXA3	15	28	43	1771.261
#237	HOXA2	15	19	34	947.577
#238	HOXA9	15	14	29	906.057
#239	MAF	15	15	30	545.292
#240	NFYA	15	24	39	834.231
#241	RFX3	15	17	32	878.97
#242	MEOX1	15	12	27	495.072
#243	EGR1	15	12	27	435.197
#244	SMAD1	15	20	35	851.189
#245	MBD1	15	17	32	616.819
#246	TLX2	15	22	37	1196.215
#247	RARA	15	26	41	960.325
#248	LHX2	15	21	36	1615.726
#249	NEUROG1	14	23	37	1278.316
#250	IKZF1	14	18	32	1356.269
#251	BATF3	14	19	33	1086.27
#252	YEATS4	14	25	39	1215.66
#253	HSF4	14	18	32	818.884
#254	RCAN1	14	18	32	769.442
#255	ZFP37	14	20	34	1383.879
#256	RORB	14	16	30	914.653
#257	TCF7	14	20	34	874.504
#258	STAT2	14	22	36	1320.715
#259	KLF5	14	16	30	794.926
#260	GATA6	14	24	38	1267.298
#261	HOXB1	14	16	30	1833.209
#262	HMX1	14	18	32	1032.459
#263	ERG	14	22	36	1419.123
#264	FOXO3	14	16	30	692.31
#265	TSC22D2	14	18	32	2706.178
#266	PRDM1	14	19	33	1556.514
#267	NPAS1	14	22	36	913.176
#268	FOXH1	14	22	36	1053.92
#269	PAX3	14	21	35	951.957
#270	HOXB3	14	14	28	818.235
#271	FOXN3	14	24	38	1029.596
#272	GATA2	14	25	39	1301.389
#273	FOXL2	14	15	29	1566.174
#274	NR0B1	14	22	36	737.078
#275	SCAND2	14	15	29	627.481
#276	EHF	14	18	32	1024.443
#277	ARNT	14	14	28	541.184
#278	TCF4	14	14	28	396.852
#279	STAT6	14	22	36	817.62
#280	SOX2	14	22	36	1311.318
#281	MNX1	14	22	36	1534.623
#282	HOXA5	14	16	30	942.747
#283	BARX1	14	17	31	1485.958
#284	ETV1	13	19	32	911.203
#285	OVOL1	13	19	32	925.028
#286	TAF1B	13	18	31	736.258
#287	E2F8	13	25	38	1039.11
#288	ZNF157	13	23	36	1075.942
#289	ESRRG	13	17	30	1037.679
#290	PHF1	13	22	35	1600.914
#291	CREB5	13	17	30	791.063
#292	TFAP2B	13	22	35	673.281
#293	FOSB	13	15	28	787.436
#294	SPI1	13	17	30	1048.158
#295	FOXB1	13	14	27	544.874
#296	RUNX1T1	13	24	37	1136.532
#297	NEUROD1	13	18	31	653.814
#298	ZNF134	13	18	31	892.946
#299	ZEB1	13	18	31	1367.189
#300	TEAD4	13	14	27	433.156
#301	C2orf3	13	19	32	909.635
#302	TP63	13	16	29	1189.967
#303	ATF6B	13	22	35	851.079
#304	ZNF80	13	22	35	1299.737
#305	PAX7	13	21	34	977.493
#306	RBPJL	13	12	25	532.212
#307	PHTF1	13	18	31	1170.118
#308	TADA2A	13	18	31	1225.421
#309	BATF	12	22	34	1428.186
#310	NKX3-2	12	17	29	957.453
#311	CBFA2T2	12	18	30	584.833
#312	ATOH1	12	16	28	509.801
#313	GBX2	12	19	31	1748.904
#314	SUPT4H1	12	17	29	740.3
#315	HLF	12	19	31	1077.227
#316	ZNF323	12	23	35	741.194
#317	ZNF93	12	16	28	825.589
#318	ZNF175	12	18	30	563.718
#319	TBX19	12	12	24	949.898
#320	ARNT2	12	20	32	631.791
#321	TBX5	12	21	33	785.663
#322	HOXA1	12	21	33	676.206
#323	ZHX3	12	19	31	927.669
#324	ZSCAN18	12	16	28	672.844
#325	KLF12	12	21	33	787.851
#326	RB1	12	21	33	1114.44
#327	SATB2	12	18	30	1095.842
#328	NR5A2	12	20	32	1116.096
#329	ZNF268	12	14	26	803.633
#330	TWIST1	12	20	32	1335.83
#331	ZNF3	12	17	29	607.863
#332	POU3F1	11	18	29	836.435
#333	SOX11	11	23	34	569.863
#334	ZNF238	11	20	31	660.436
#335	PAX6	11	20	31	563.836
#336	PRDM2	11	20	31	814.726
#337	GSC2	11	19	30	849.446
#338	LHX6	11	19	30	580.671
#339	FOXA2	11	19	30	729.266
#340	NR3C2	11	19	30	625.142
#341	RFXAP	11	17	28	633.172
#342	MAFK	11	19	30	885.938
#343	MSC	11	20	31	664.216
#344	ETV4	11	18	29	834.963
#345	HOXB7	11	20	31	1060.824
#346	DBP	11	22	33	1362.77
#347	ZNF643	11	21	32	694.547
#348	NR4A1	11	23	34	680.615
#349	OLIG2	11	16	27	867.408
#350	RUNX2	11	17	28	674.004
#351	FOXP3	11	23	34	974.614
#352	HNF4A	11	20	31	1216.03
#353	SOX17	11	13	24	610.23
#354	FOXD3	11	25	36	1353.972
#355	PAX4	11	17	28	1048.658
#356	TRIM25	11	17	28	1298.777
#357	GTF2H3	11	18	29	659.11
#358	FOS	10	19	29	620.743
#359	ZNF75D	10	13	23	802.673
#360	EGR4	10	24	34	1249.28
#361	FOXK2	10	13	23	496.217
#362	EMX1	10	17	27	731.28
#363	FOXD1	10	21	31	1154.661
#364	NR5A1	10	18	28	757.918
#365	MYT1	10	16	26	489.688
#366	NRL	10	18	28	930.939
#367	ELK4	10	21	31	1752.134
#368	THRA	10	23	33	999.027
#369	TLX3	10	18	28	740.523
#370	ELK1	10	18	28	520.911
#371	EGR2	10	13	23	510.948
#372	HEY1	10	23	33	904.376
#373	MEF2D	10	16	26	554.2
#374	TSC22D3	10	20	30	888.207
#375	ZNF81	10	20	30	843.45
#376	BHLHE41	10	16	26	566.143
#377	HOXC13	10	17	27	464.737
#378	LHX1	10	25	35	832.991
#379	ESR2	10	20	30	714.611
#380	FOSL2	10	17	27	702.159
#381	HESX1	10	19	29	730.376
#382	CREM	10	19	29	1022.538
#383	TBX6	10	21	31	876.301
#384	ALX3	10	22	32	807.71
#385	NKX2-5	10	21	31	465.756
#386	POU1F1	10	24	34	1217.753
#387	ZNF236	10	20	30	928.163
#388	LZTS1	9	22	31	630.801
#389	NR2F2	9	23	32	1234.349
#390	DMRT1	9	23	32	924.95
#391	FOXJ1	9	19	28	647.308
#392	MEF2A	9	19	28	696.829
#393	IRF5	9	19	28	562.454
#394	HOXD1	9	22	31	1067.215
#395	TEF	9	16	25	546.856
#396	PRRX2	9	20	29	754.715
#397	SOX9	9	21	30	1009.003
#398	MYT1L	9	16	25	659.975
#399	MSX1	9	16	25	647.699
#400	DLX2	9	21	30	812.454
#401	HNF1A	9	19	28	1127.271
#402	HMG20B	9	19	28	578.559
#403	NFATC1	9	23	32	947.056
#404	POU4F1	9	24	33	851.681
#405	MMP14	9	28	37	1003.16
#406	PTH	9	21	30	803.18
#407	FOXO4	9	21	30	864.924
#408	PPARA	9	16	25	586.485
#409	HOXD11	9	17	26	698.108
#410	TCF15	9	24	33	1012.301
#411	BRD8	9	21	30	917.255
#412	EN2	9	23	32	629.582
#413	ZNF187	9	15	24	431.729
#414	HOPX	9	21	30	545.304
#415	SOX15	9	16	25	552.158
#416	POU4F3	9	12	21	153.243
#417	SIX1	8	25	33	582.655
#418	PROX1	8	16	24	435.461
#419	NKX2-1	8	14	22	355.447
#420	ZNF154	8	20	28	426.296
#421	PAX8	8	19	27	574.237
#422	GCM1	8	22	30	683.113
#423	VDR	8	21	29	499.047
#424	SOX18	8	22	30	710.964
#425	POU3F3	8	21	29	608.796
#426	CEBPE	8	19	27	977.137
#427	TCF12	8	20	28	1085.847
#428	NFIB	8	16	24	216.904
#429	SOX30	8	18	26	684.396
#430	REST	8	23	31	304.323
#431	NFIX	8	22	30	468.426
#432	ZNF167	8	19	27	471.439
#433	SCML1	8	21	29	536.269
#434	MECOM	8	21	29	806.332
#435	ZSCAN12	8	14	22	323.173
#436	TBX1	8	24	32	1164.529
#437	NPAS2	8	23	31	1175.737
#438	MLLT10	8	21	29	296.933
#439	HOXA10	8	21	29	843.794
#440	ZNF135	8	24	32	845.084
#441	PGR	8	17	25	436.935
#442	MYCN	8	29	37	764.466
#443	ZIC1	8	20	28	323.457
#444	POU3F2	8	22	30	1132.71
#445	FOXD2	8	19	27	369.209
#446	FOXI1	7	22	29	346.56
#447	PLAG1	7	24	31	597.815
#448	IRF4	7	23	30	589.345
#449	HOXD3	7	20	27	730.336
#450	ZNF202	7	19	26	737.22
#451	KDM5B	7	16	23	349.273
#452	YY1	7	18	25	534.724
#453	SRY	7	23	30	733.316
#454	NR2C1	7	21	28	693.526
#455	POU5F1B	6	20	26	461.443
#456	RARB	6	24	30	583.185
#457	NR6A1	6	22	28	384.976
#458	ZNF639	6	20	26	428.917
#459	SIM1	6	23	29	621.287
#460	PCGF2	6	20	26	427.633
#461	MYF5	6	24	30	582.201
#462	HOXB6	6	24	30	627.173
#463	PITX2	6	27	33	693.82
#464	CUX2	6	20	26	774.863
#465	NFX1	6	22	28	378.867
#466	SOX21	6	20	26	498.75
#467	ASCL2	6	23	29	528.674
#468	ONECUT1	6	17	23	521.692
#469	IRX4	6	26	32	498.159
#470	ZFP36L1	6	19	25	387.433
#471	ST18	6	23	29	878.358
#472	ZNF117	5	15	20	220.751
#473	WNT5A	5	20	25	388.263
#474	PAX5	5	22	27	748.826
#475	NR1I2	5	22	27	741.518
#476	HOXD13	5	22	27	396.818
#477	ZNF287	5	24	29	439.805
#478	NR2F1	5	30	35	621.923
#479	ASCL1	5	30	35	990.59
#480	VTN	5	19	24	377.891
#481	PHOX2A	5	27	32	465.729
#482	STAT1	5	23	28	440.127
#483	DLX6	5	26	31	641.567
#484	SNAPC5	5	25	30	649.231
#485	FOXG1	5	26	31	431.477
#486	PPARG	5	23	28	346.789
#487	ETV2	5	19	24	462.581
#488	TCF3	4	24	28	267.706
#489	HEY2	4	21	25	631.68
#490	MEOX2	4	27	31	451.768
#491	RARG	4	20	24	316.572
#492	POU6F2	4	20	24	257.176
#493	TAF13	4	30	34	501.144
#494	PPARD	4	22	26	207.847
#495	MSRB2	4	20	24	552.721
#496	POU6F1	3	17	20	86.784
#497	SCRT1	3	21	24	387.868
#498	TCF21	2	20	22	267.919
#499	POU2F3	2	30	32	322.92
#500	ERF	2	18	20	213.426