Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ERG	46	1	47	629.179
#2	UHRF1	41	3	44	490.448
#3	FLI1	41	3	44	212.466
#4	HOPX	37	3	40	795.988
#5	GATA6	35	6	41	1600.411
#6	MEF2C	33	6	39	625.889
#7	RUNX1T1	33	9	42	1937.982
#8	KLF9	32	4	36	956.859
#9	TCF4	32	4	36	1569.61
#10	SOX7	31	3	34	1288.132
#11	CBFA2T2	31	1	32	41.925
#12	CREBL2	30	4	34	1522.07
#13	SOX18	29	7	36	515.055
#14	NR3C2	29	4	33	196.077
#15	ETS2	29	4	33	171.808
#16	SOX17	28	5	33	254.526
#17	FOXM1	28	6	34	2276.189
#18	PEG3	27	6	33	6150.611
#19	JDP2	27	6	33	3567.926
#20	GATA2	27	7	34	2861.167
#21	WNT5A	25	16	41	3869.553
#22	TBX2	25	6	31	2256.482
#23	ZEB1	25	7	32	623.705
#24	RUNX1	25	8	33	1708.022
#25	ZNF207	25	4	29	1332.314
#26	BATF3	25	9	34	3262.668
#27	TCF7L1	25	5	30	412.064
#28	PRRX1	25	7	32	1135.833
#29	ZSCAN18	25	3	28	803.777
#30	TRIM28	25	2	27	557.328
#31	HHEX	24	8	32	1753.923
#32	TFEC	24	14	38	4907.847
#33	HOXD8	24	10	34	1723.89
#34	IKZF1	24	0	24	0
#35	SMAD6	24	9	33	890.391
#36	HMG20B	23	6	29	967.819
#37	BLZF1	23	9	32	2945.806
#38	NFIB	23	8	31	2053.447
#39	HCLS1	22	6	28	1344.961
#40	HSF2	22	8	30	3013.411
#41	SPEN	22	7	29	955.895
#42	SLC2A4RG	22	3	25	675.988
#43	ATF2	21	2	23	1548.564
#44	NKX2-1	21	3	24	1371.259
#45	HEYL	21	2	23	467.244
#46	FOXF2	21	10	31	1848.19
#47	MEIS1	21	12	33	979.19
#48	FOXP1	21	11	32	3296.713
#49	GTF2I	20	6	26	359.701
#50	FOXF1	20	10	30	1835.78
#51	GATAD2B	19	4	23	1060.376
#52	TCF21	19	6	25	515.617
#53	SP1	19	3	22	238.997
#54	SNAI2	19	12	31	3087.288
#55	E2F5	19	10	29	2200.201
#56	MLL	19	9	28	2464.559
#57	HLF	19	9	28	1008.41
#58	E2F7	18	5	23	1213.868
#59	CNOT8	18	8	26	2780.47
#60	TARDBP	18	7	25	1684.344
#61	LMO4	18	10	28	2217.922
#62	STAT2	18	11	29	2083.469
#63	TAL1	18	4	22	199.044
#64	KLF2	18	4	22	309.379
#65	KLF3	18	4	22	477.787
#66	SOX13	18	8	26	1498.134
#67	PRDM1	17	9	26	2173.135
#68	THRA	17	8	25	1118.164
#69	NR1H2	17	2	19	1394.883
#70	LCOR	17	9	26	1369.662
#71	TCF12	17	6	23	503.539
#72	HOXA4	17	11	28	3467.221
#73	ZFPM2	17	11	28	3456.118
#74	ATF1	16	9	25	2714.367
#75	NR4A1	16	4	20	546.767
#76	NFE2L3	16	9	25	2462.943
#77	KLF11	16	12	28	1521.439
#78	NR2C1	16	14	30	5453.903
#79	TFAM	16	11	27	2613.839
#80	ZFHX4	16	12	28	3284.151
#81	PPARA	16	14	30	4647.01
#82	HEY2	16	9	25	347.502
#83	EBF1	16	6	22	62.969
#84	NFIA	16	12	28	2577.541
#85	ZFP36L2	16	7	23	347.959
#86	ZNF256	16	10	26	1635.426
#87	TRIM22	16	8	24	2178.833
#88	CREM	16	4	20	2100.713
#89	ATF5	16	12	28	3381.34
#90	ZNF165	15	13	28	1929.932
#91	LZTS1	15	11	26	424.47
#92	EHF	15	7	22	999.156
#93	TSHZ3	15	15	30	3546.629
#94	CBFA2T3	15	5	20	945.238
#95	SOLH	15	8	23	924.394
#96	TRPS1	15	10	25	4078.806
#97	ARNTL2	15	10	25	1478.376
#98	ETS1	15	9	24	756.825
#99	ZNF274	15	13	28	3962.689
#100	ETV1	15	13	28	2353.871
#101	DBP	15	11	26	3879.909
#102	ZNF148	15	8	23	2228.02
#103	TFCP2	15	6	21	1181.706
#104	AFF4	14	7	21	2099.691
#105	RORA	14	11	25	2297.945
#106	ZNF45	14	7	21	2160.101
#107	FOXP4	14	7	21	1168.048
#108	ZNF91	14	13	27	2585.224
#109	NANOGNB	14	7	21	710.508
#110	EOMES	14	4	18	1021.377
#111	NFE2L2	14	16	30	4416.372
#112	ZNF397	14	7	21	908.658
#113	ZNF277	14	6	20	756.897
#114	IRX2	14	9	23	1758.091
#115	RXRA	14	8	22	777.019
#116	MAX	14	7	21	899.904
#117	PTTG1	14	8	22	845.917
#118	NFATC3	14	14	28	1041.051
#119	RERE	14	5	19	861.256
#120	CTNNB1	14	9	23	1476.105
#121	TSHZ1	13	10	23	3397.449
#122	KLF4	13	12	25	2990.723
#123	NR4A3	13	8	21	1688.432
#124	ZNF268	13	11	24	3710.233
#125	RXRB	13	13	26	931.368
#126	ATF7	13	7	20	2431.409
#127	SMAD4	13	6	19	735.664
#128	NR3C1	13	13	26	8386.689
#129	ZBTB48	13	3	16	156.483
#130	PAX8	13	10	23	2583.97
#131	NR1H4	13	12	25	4777.211
#132	ZNF83	13	10	23	1238.414
#133	HEY1	13	7	20	2240.327
#134	AFF1	13	12	25	2291.293
#135	CREB1	13	7	20	675.301
#136	ZNF135	13	7	20	1840.298
#137	JUND	12	7	19	1399.667
#138	TBX5	12	12	24	2348.246
#139	LEF1	12	9	21	1649.148
#140	EPAS1	12	10	22	1485.722
#141	FOSL1	12	9	21	1255.266
#142	STAT1	12	10	22	1629.197
#143	BCL11B	12	6	18	683.657
#144	MAFB	12	7	19	957.408
#145	HMGA1	12	15	27	1862.625
#146	PAX6	12	10	22	1046.126
#147	SATB1	12	9	21	2365.822
#148	KDM5A	12	11	23	4067.456
#149	PHF1	12	6	18	318.897
#150	ZNF93	12	11	23	1325.827
#151	NFYC	12	16	28	2641.944
#152	DDIT3	12	11	23	1969.155
#153	C5orf41	12	8	20	2143.472
#154	SMAD3	11	10	21	3682.224
#155	FOSB	11	3	14	394.175
#156	PPARG	11	12	23	468.695
#157	ESRRG	11	18	29	4208.884
#158	MLLT10	11	8	19	1057.938
#159	ZEB2	11	12	23	2113.683
#160	NFYB	11	8	19	1365.321
#161	ZNF70	11	8	19	2588.323
#162	ZNF217	11	8	19	944.087
#163	HNF4A	11	15	26	2171.173
#164	RUNX3	11	7	18	754.918
#165	RORC	11	15	26	2869.679
#166	HNF4G	11	16	27	4341.712
#167	KLF16	11	8	19	1235.643
#168	RB1	11	8	19	1257.564
#169	PRRX2	11	9	20	2104.93
#170	LHX8	11	7	18	1352.158
#171	WT1	11	12	23	1742.496
#172	RUNX2	11	5	16	168.011
#173	HOXC9	11	11	22	2498.313
#174	NPAS2	11	8	19	117.07
#175	ZIC2	11	9	20	2122.09
#176	GLIS3	10	12	22	2000.83
#177	SOX1	10	7	17	815.263
#178	KLF5	10	12	22	2389.443
#179	NFIL3	10	8	18	1096.053
#180	NFAT5	10	7	17	586.497
#181	RCOR1	10	5	15	398.95
#182	CEBPA	10	10	20	1440.151
#183	C1orf85	10	9	19	988.993
#184	FOXK1	10	12	22	2333.551
#185	TSC22D3	10	11	21	2276.519
#186	NR4A2	10	5	15	1130.376
#187	CNOT7	10	10	20	3981.454
#188	HOXD10	10	10	20	1360.596
#189	GAS7	10	11	21	1623.307
#190	ZNF238	10	14	24	3009.22
#191	ZNF131	10	15	25	1247.086
#192	CREB5	10	10	20	3399.688
#193	STAT4	10	7	17	1130.444
#194	ZNF281	10	15	25	3934.937
#195	IRF8	10	3	13	316.701
#196	ZNF134	10	10	20	1110.746
#197	ZFHX3	10	7	17	2190.156
#198	CSRNP1	10	6	16	742.94
#199	MLXIPL	10	8	18	874.949
#200	VAV1	10	6	16	604.91
#201	PROX1	10	9	19	3273.718
#202	TBX3	10	13	23	694.682
#203	RBCK1	10	11	21	1606.46
#204	ZNF323	9	12	21	1767.835
#205	CREB3L1	9	10	19	1703.323
#206	HOXD9	9	10	19	2143.575
#207	TAF5L	9	10	19	619.449
#208	MITF	9	9	18	2763.742
#209	SOX6	9	9	18	3173.486
#210	ENO1	9	10	19	889.997
#211	SCAND1	9	13	22	1754.237
#212	ZHX2	9	12	21	1346.627
#213	ZNF33B	9	14	23	2013.319
#214	PRDM2	9	13	22	1325.737
#215	KLF12	9	11	20	937.419
#216	TULP4	9	13	22	3233.422
#217	NFKB2	9	13	22	1222.693
#218	CEBPD	9	10	19	1080.228
#219	TSC22D1	9	9	18	649.126
#220	HNF1B	9	15	24	2675.158
#221	MEIS2	9	13	22	2198.407
#222	HOXB7	9	7	16	219.522
#223	ELF5	9	4	13	102.161
#224	ZBTB38	9	13	22	1260.43
#225	PBX2	9	7	16	1005.703
#226	HIC1	9	4	13	136.593
#227	ZNF138	9	10	19	2123.098
#228	NFATC4	9	8	17	1692.639
#229	RFXAP	9	8	17	1750.671
#230	ZNF24	9	10	19	1245.233
#231	HSF4	9	13	22	1871.453
#232	TEF	9	9	18	2285.245
#233	SCML1	9	14	23	2586.358
#234	C11orf9	9	9	18	2344.209
#235	MAF	9	12	21	990.399
#236	EN1	9	6	15	796.701
#237	FOXP2	9	9	18	2410.837
#238	MEF2A	9	9	18	1867.516
#239	STAT6	9	5	14	360.082
#240	FOXS1	9	9	18	1593.343
#241	DLX4	9	12	21	706.085
#242	RORB	9	12	21	3654.037
#243	NOTCH1	8	10	18	2094.862
#244	GATA3	8	8	16	1588.133
#245	IRF6	8	10	18	1882.561
#246	MAFF	8	12	20	2312.079
#247	JUNB	8	4	12	246.11
#248	NFIX	8	18	26	1586.944
#249	CEBPB	8	11	19	2276.802
#250	NR2F2	8	9	17	905.474
#251	TSHZ2	8	13	21	1677.718
#252	GTF2H2	8	10	18	516.604
#253	NFIC	8	9	17	676.983
#254	PLSCR1	8	12	20	2517.694
#255	ERF	8	10	18	1098.051
#256	PBX3	8	14	22	1819.142
#257	FOS	8	8	16	417.548
#258	ZSCAN2	8	14	22	1914.053
#259	FOXO3	8	16	24	1843.028
#260	NR2F1	8	13	21	1158.679
#261	PHTF1	8	10	18	1268.334
#262	FUBP1	8	7	15	724.201
#263	IRF9	8	13	21	1497.732
#264	MAFK	8	12	20	822.569
#265	TFDP1	8	7	15	654.312
#266	HMGA2	8	10	18	718.44
#267	BACH1	8	8	16	1294.54
#268	YEATS4	7	9	16	1036.55
#269	PURA	7	8	15	707.931
#270	SMAD9	7	8	15	913.682
#271	ZHX3	7	11	18	2522.239
#272	ESR1	7	16	23	1670.578
#273	PKNOX2	7	5	12	170.724
#274	HOXC10	7	12	19	863.41
#275	SPI1	7	7	14	522.687
#276	TBX15	7	10	17	1233.708
#277	MECOM	7	10	17	690.526
#278	TCF7	7	17	24	1088.435
#279	RARB	7	12	19	3116.044
#280	GLI2	7	8	15	761.359
#281	FOXO1	7	9	16	445.944
#282	PGR	7	7	14	391.227
#283	NR1H3	7	11	18	1404.464
#284	PLAG1	7	12	19	758.09
#285	SCMH1	7	12	19	1876.991
#286	SMAD5	7	8	15	425.48
#287	ZHX1	7	11	18	665.041
#288	ARNT2	7	14	21	2374.1
#289	TFEB	7	10	17	1113.983
#290	FOSL2	7	15	22	1839.023
#291	ZNF189	7	11	18	1203.121
#292	CDKN2A	7	14	21	2901.018
#293	LHX9	7	5	12	353.204
#294	HES1	7	10	17	893.795
#295	TSC22D4	7	8	15	1039.057
#296	EGR3	7	7	14	852.729
#297	MNX1	7	10	17	344.133
#298	TWIST2	7	9	16	1693.224
#299	ZXDC	7	9	16	870.214
#300	EGR2	7	10	17	1142.697
#301	BACH2	7	7	14	816.327
#302	RFX1	7	9	16	1539.064
#303	TRERF1	7	10	17	1011.047
#304	KLF10	7	5	12	148.865
#305	TFDP2	7	13	20	1714.364
#306	ZFP37	7	16	23	1160.045
#307	IRF1	7	5	12	701.975
#308	BATF	6	9	15	415.97
#309	HOXA1	6	11	17	1201.387
#310	HNF1A	6	8	14	616.818
#311	SOX2	6	5	11	214.526
#312	AHR	6	10	16	660.964
#313	EMX1	6	8	14	534.577
#314	ZNF117	6	13	19	1675.406
#315	CTBP1	6	16	22	1220.134
#316	GABPA	6	14	20	922.46
#317	TSC22D2	6	16	22	908.434
#318	HOXD4	6	10	16	1086.418
#319	ARNTL	6	10	16	671.155
#320	FOXN3	6	9	15	627.751
#321	TFAP2A	6	12	18	1018.585
#322	MXD1	6	10	16	746.616
#323	NR5A2	6	11	17	746.44
#324	HOXA9	6	10	16	2255.167
#325	MYC	6	8	14	452.636
#326	E2F8	6	7	13	720.252
#327	MBD1	6	11	17	1283.133
#328	STAT3	6	13	19	942.879
#329	TEAD2	6	16	22	1423.564
#330	MSRB2	6	14	20	1943.39
#331	GLI3	6	19	25	1408.321
#332	GABPB1	6	15	21	626.048
#333	ELF3	6	9	15	1867.241
#334	CREB3L2	6	11	17	1236.781
#335	ALS2CR8	6	12	18	733.58
#336	HOXA10	6	14	20	1476.985
#337	TWIST1	5	7	12	463.816
#338	ZNF367	5	11	16	1866.29
#339	HOXB2	5	13	18	618.864
#340	HOXA3	5	12	17	1847.806
#341	STRN3	5	9	14	985.335
#342	DLX1	5	10	15	1015.125
#343	ONECUT2	5	9	14	873.187
#344	PBX1	5	13	18	1637.39
#345	CSDA	5	13	18	481.937
#346	TCF19	5	13	18	494.89
#347	HOXA11	5	9	14	600.862
#348	HOXB9	5	11	16	649.688
#349	HOXD11	5	9	14	846.251
#350	AEBP1	5	17	22	490.843
#351	GATAD1	5	10	15	1202.985
#352	VTN	5	5	10	261.363
#353	HOXB13	5	12	17	927.279
#354	NFATC1	5	9	14	356.535
#355	BTG2	5	11	16	1787.854
#356	SALL1	5	12	17	1619.692
#357	NR2E1	5	14	19	1442.391
#358	SMAD1	5	12	17	2204.51
#359	MZF1	5	9	14	754.794
#360	IRX3	5	10	15	820.456
#361	TP53	5	11	16	601.141
#362	POU5F1B	5	14	19	1551.06
#363	EGR1	5	10	15	1025.273
#364	SATB2	5	17	22	2174.947
#365	MESP1	5	8	13	526.523
#366	ZNF628	5	6	11	193.793
#367	THRB	5	15	20	1304.986
#368	MSX2	5	11	16	920.61
#369	LHX6	5	15	20	965.087
#370	HSF1	5	6	11	226.234
#371	AR	5	10	15	869.187
#372	TFAP2C	5	10	15	3046.935
#373	NKX3-1	5	12	17	1381.132
#374	FOXG1	5	5	10	364.404
#375	SCAND3	5	10	15	1311.989
#376	XBP1	5	9	14	883.591
#377	FOXQ1	4	18	22	1741.652
#378	CITED2	4	18	22	1531.894
#379	FOXA2	4	10	14	897.582
#380	HOXD1	4	10	14	740.522
#381	REL	4	14	18	326.458
#382	NFYA	4	14	18	1087.99
#383	VDR	4	9	13	254.758
#384	BHLHE41	4	9	13	711.681
#385	BATF2	4	8	12	441.762
#386	IRF4	4	9	13	936.326
#387	FOXC2	4	14	18	910.417
#388	GLIS2	4	12	16	603.341
#389	SP140	4	9	13	469.775
#390	ATF3	4	9	13	481.811
#391	BHLHE40	4	13	17	303.227
#392	TEAD1	4	11	15	620.835
#393	GTF2H3	4	9	13	427.449
#394	L3MBTL4	4	12	16	2084.849
#395	PGBD1	4	9	13	569.616
#396	SP4	4	12	16	886.69
#397	MSC	4	15	19	2362.038
#398	PURB	4	12	16	1042.614
#399	MYCL1	4	8	12	484.747
#400	ARID4A	4	6	10	337.222
#401	ZNF140	4	5	9	513.008
#402	SIM1	4	20	24	1889.196
#403	E2F3	4	14	18	1405.667
#404	SIM2	4	7	11	615.002
#405	SLC30A9	4	12	16	2026.633
#406	BCL6	3	10	13	429.7
#407	HOXC4	3	8	11	200.396
#408	HIRA	3	10	13	457.775
#409	POU2F2	3	9	12	999.394
#410	ZNF202	3	5	8	158.145
#411	DLX2	3	5	8	74.081
#412	MEOX1	3	9	12	334.344
#413	IRX1	3	11	14	203.556
#414	SOX11	3	13	16	493.573
#415	TGIF1	3	12	15	1555.971
#416	ETV5	3	11	14	1405.503
#417	SOX4	3	11	14	741.827
#418	MEOX2	3	13	16	978.998
#419	TAF10	3	15	18	1794.793
#420	NR0B1	3	7	10	1453.71
#421	IRX5	3	15	18	1143.829
#422	PITX2	3	13	16	1107.572
#423	NFATC2	3	16	19	1106.816
#424	LASS6	3	15	18	608.398
#425	IRF7	3	9	12	235.627
#426	FOXJ3	3	14	17	983.111
#427	ZNF167	3	9	12	417.291
#428	ETV6	3	13	16	815.452
#429	SOX9	3	17	20	1043.318
#430	CSRNP3	3	9	12	286.116
#431	SIX2	3	9	12	344.588
#432	MEIS3P1	3	12	15	1041.402
#433	RCAN1	3	12	15	1120.067
#434	ZNF85	3	10	13	302.523
#435	FOXA1	3	7	10	196.169
#436	HOXD3	3	8	11	346.309
#437	NFX1	3	8	11	59.514
#438	CREBZF	3	7	10	378.326
#439	HOXA7	3	14	17	435.917
#440	EN2	3	14	17	573.569
#441	CREB3L4	3	7	10	587.909
#442	BNC1	2	9	11	113.669
#443	ZIC1	2	5	7	157.669
#444	KLF7	2	14	16	674.785
#445	TCF7L2	2	16	18	861.504
#446	SOX5	2	9	11	374.895
#447	ZNF396	2	13	15	1563.95
#448	TAF5	2	13	15	329.343
#449	SIX4	2	13	15	329.812
#450	ZSCAN16	2	12	14	1685.093
#451	KLF15	2	9	11	330.353
#452	POU6F1	2	9	11	645.578
#453	RARA	2	8	10	152.748
#454	POU2F3	2	9	11	453.228
#455	HOXA13	2	15	17	507.553
#456	SIX1	2	11	13	306.621
#457	HIF3A	2	8	10	189.071
#458	ELK3	2	12	14	416.149
#459	JUN	2	10	12	484.131
#460	NFE2L1	2	10	12	195.654
#461	IRF2	2	14	16	159.638
#462	SREBF1	2	11	13	243.102
#463	OVOL1	2	9	11	211.421
#464	SOX12	2	8	10	292.701
#465	FOXC1	2	14	16	1661.527
#466	GATA5	2	6	8	175.39
#467	NR1D2	2	15	17	358.458
#468	HOXB6	2	8	10	242.554
#469	RELB	2	13	15	165.916
#470	HOXB8	2	10	12	302.834
#471	TEAD4	2	15	17	626.653
#472	ZFP36L1	2	17	19	809.395
#473	FOXD1	2	15	17	664.268
#474	CBL	1	13	14	76.088
#475	ETV7	1	9	10	376.46
#476	MMP14	1	11	12	471.31
#477	BCL3	1	15	16	126.86
#478	SALL2	1	11	12	151.254
#479	MTA1	1	15	16	1064.482
#480	TCFL5	1	9	10	237.953
#481	HOXB3	1	13	14	396.966
#482	ARX	1	11	12	203.871
#483	CREB3L3	1	15	16	129.519
#484	ZNF92	1	8	9	23.046
#485	HOXA2	1	11	12	1038.513
#486	FOXO6	1	11	12	71.746
#487	HOXA5	1	13	14	372.432
#488	GTF2H4	1	9	10	265.424
#489	FOXL1	1	14	15	710.936
#490	TP63	1	11	12	247.184
#491	KLF6	1	15	16	93.783
#492	SPIB	1	7	8	67.793
#493	TRIM29	1	10	11	605.772
#494	CCRN4L	0	13	13	0
#495	IRF5	0	8	8	0
#496	TFCP2L1	0	11	11	0
#497	OLIG2	0	7	7	0
#498	HMBOX1	0	12	12	0
#499	MSX1	0	13	13	0
#500	POU4F1	0	5	5	0