Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	MGA	72	8	80	362.06
#2	NFYC	66	12	78	1522.605
#3	SNAI2	66	2	68	2056.509
#4	TCF4	64	2	66	546.691
#5	ELK3	63	3	66	29.19
#6	MAFB	63	1	64	14.819
#7	NPAT	60	10	70	1937.956
#8	GATA3	58	5	63	464.673
#9	FOXA1	58	0	58	0
#10	TCF3	55	13	68	996.132
#11	TSHZ2	54	6	60	722.593
#12	NR4A3	54	6	60	1337.932
#13	TADA3	54	17	71	2172.187
#14	ESR1	52	8	60	456.683
#15	FOXN3	52	9	61	3490.378
#16	TAL1	51	3	54	213.41
#17	HAND1	51	6	57	378.727
#18	XBP1	49	1	50	4.077
#19	EPAS1	49	15	64	1113.94
#20	AEBP1	47	5	52	669.207
#21	TCFL5	47	11	58	1565.955
#22	HEY1	46	8	54	244.064
#23	NFE2	46	5	51	317.461
#24	PHOX2B	46	15	61	3013.943
#25	E2F3	45	12	57	1698.396
#26	NFE2L1	45	6	51	579.133
#27	AFF1	45	9	54	1631.35
#28	MITF	45	16	61	6183.536
#29	RFXANK	44	11	55	775.864
#30	TAF1B	43	10	53	1279.697
#31	SPDEF	42	4	46	45.82
#32	EN1	42	8	50	702.498
#33	MEF2C	42	10	52	355.652
#34	ENO1	41	9	50	648.98
#35	ZNF131	41	8	49	417.959
#36	ISL1	41	13	54	1188.634
#37	CUX1	41	13	54	774.551
#38	MAX	41	10	51	1505.275
#39	MAF	40	8	48	137.479
#40	NR3C1	39	7	46	138.69
#41	MMP14	39	11	50	1054.654
#42	RUNX3	39	9	48	489.474
#43	IRF8	38	8	46	488.616
#44	TCEAL1	38	7	45	217.044
#45	ELF1	38	14	52	1159.882
#46	RFX3	38	18	56	1728.62
#47	ZIC3	37	16	53	975.67
#48	BHLHE41	37	13	50	1486.266
#49	ZNF83	37	12	49	992.78
#50	LASS6	36	6	42	158.191
#51	ZEB1	36	13	49	454.186
#52	PRRX1	36	5	41	46.962
#53	NOTCH1	35	9	44	819.698
#54	NFIB	35	20	55	1683.726
#55	GAS7	35	12	47	389.726
#56	FOXC1	35	4	39	464.405
#57	E2F6	34	13	47	2537.72
#58	HCLS1	34	9	43	378.819
#59	STAT1	34	15	49	551.385
#60	ZGPAT	34	17	51	592.233
#61	KLF9	33	19	52	1195.114
#62	HINFP	33	19	52	2010.604
#63	TFEC	32	8	40	437.676
#64	TFE3	32	9	41	1041.162
#65	HOXA11	32	16	48	1031.838
#66	FLI1	32	11	43	634.417
#67	NR2F1	32	13	45	297.131
#68	MYC	32	17	49	2890.276
#69	ZEB2	32	9	41	380.847
#70	ATF1	31	12	43	1251.37
#71	AHR	31	12	43	1108.628
#72	CSDA	31	13	44	1710.761
#73	ZFP36L2	30	13	43	1459.765
#74	ETV1	30	19	49	798.306
#75	JUN	30	15	45	888.649
#76	SP140	30	8	38	654.778
#77	SLC2A4RG	30	16	46	1089.235
#78	AR	30	10	40	196.058
#79	ZNF132	30	10	40	1039.986
#80	ETS1	30	19	49	2249.034
#81	ZNF394	30	7	37	1059.761
#82	POU3F1	29	13	42	1442.179
#83	TRIM22	29	9	38	505.016
#84	CTBP1	29	14	43	821.531
#85	CITED2	29	13	42	541.908
#86	NR1I3	29	17	46	1644.092
#87	MECOM	29	23	52	1619.191
#88	YBX1	29	8	37	184.54
#89	NFATC3	28	18	46	1663.078
#90	TRIM29	28	13	41	663.35
#91	NR2F2	28	19	47	1624.759
#92	CREM	28	21	49	1378.397
#93	JUND	28	14	42	706.194
#94	EGR1	28	14	42	2550.142
#95	HIRA	28	17	45	2083.009
#96	GTF2I	27	13	40	1031.32
#97	FOXO1	27	11	38	249.416
#98	HMGA1	27	13	40	658.042
#99	NFIC	27	12	39	1131.352
#100	SOX10	27	9	36	644.056
#101	PBX1	27	19	46	836.432
#102	ATF6	27	13	40	1445.67
#103	PLSCR1	27	10	37	1198.344
#104	CDKN2A	27	8	35	1484.966
#105	CNOT8	26	14	40	992.127
#106	PHOX2A	26	17	43	1112.126
#107	RUNX1T1	26	15	41	357.734
#108	GATA4	26	13	39	380.167
#109	MTA2	25	19	44	843.513
#110	NFYB	25	18	43	1216.306
#111	SUPT4H1	25	14	39	1118.517
#112	SOX13	25	11	36	303.835
#113	GTF2H3	25	17	42	1040.367
#114	MYBL2	25	11	36	616.957
#115	ESRRA	25	14	39	446.052
#116	NR5A1	24	16	40	767.764
#117	HOXD11	24	19	43	2371.292
#118	SREBF1	24	13	37	808.384
#119	HSF2	24	13	37	2222.075
#120	TCF7L2	24	15	39	1237.987
#121	HMGB2	23	15	38	538.082
#122	TBX10	23	15	38	1233.831
#123	ATF5	23	19	42	2307.193
#124	LASS2	23	10	33	284.557
#125	GATAD1	23	18	41	1440.844
#126	REXO4	23	23	46	1623.783
#127	ZNF91	23	16	39	1038.892
#128	TWIST1	23	10	33	200.087
#129	GABPA	23	11	34	1179.142
#130	POU3F4	23	19	42	2215.307
#131	CEBPB	23	8	31	1076.391
#132	FOXM1	23	11	34	711.582
#133	TFAM	23	12	35	267.363
#134	CBL	23	16	39	1068.222
#135	MAFF	22	13	35	526.532
#136	ZFPM2	22	9	31	1059.492
#137	ZXDC	22	16	38	1176.345
#138	STAT3	22	14	36	2310.594
#139	PBX3	22	13	35	830.483
#140	MZF1	22	15	37	831.213
#141	MXD1	22	14	36	270.365
#142	CEBPD	22	17	39	1433.108
#143	TAF12	22	17	39	1512.064
#144	GLI2	22	11	33	621.07
#145	ARNT	22	16	38	624.466
#146	POU4F1	21	21	42	1244.887
#147	SMAD5	21	13	34	945.947
#148	NR1H4	21	13	34	708.783
#149	FOS	21	21	42	1667.259
#150	LZTS1	21	17	38	689.008
#151	MYT1L	21	17	38	1767.598
#152	ETV5	21	16	37	1555.915
#153	ELF5	21	14	35	368.602
#154	POU5F1B	21	14	35	1456.245
#155	MEF2A	21	20	41	966.983
#156	LMO4	21	19	40	1032.67
#157	HSF1	21	18	39	1211.488
#158	KLF6	20	25	45	1416.712
#159	EGR3	20	15	35	394.837
#160	TFEB	20	17	37	744.636
#161	SOX18	20	19	39	665.623
#162	ZNF174	20	27	47	1168.238
#163	TEAD4	20	20	40	2804.822
#164	SOX4	20	19	39	939.159
#165	NKX2-1	20	18	38	859.475
#166	IRX5	20	16	36	1207.886
#167	HOXB2	20	19	39	1587.138
#168	FUBP1	20	12	32	1109.984
#169	BATF3	19	19	38	489.901
#170	GABPB1	19	20	39	1107.639
#171	PPARD	19	20	39	1619.405
#172	HNF1B	19	18	37	845.21
#173	BHLHE40	19	19	38	829.814
#174	FBXW7	19	9	28	411.859
#175	NFE2L3	19	13	32	262.586
#176	NFIX	19	21	40	1687.479
#177	PKNOX2	19	17	36	1789.682
#178	EGR2	19	14	33	410.936
#179	GATAD2A	19	16	35	1522.266
#180	ERF	19	20	39	1157.022
#181	TFAP2B	18	22	40	631.863
#182	NFYA	18	28	46	1066.455
#183	E2F5	18	27	45	1932.935
#184	ARNTL2	18	16	34	1064.772
#185	BRD8	18	18	36	1165.709
#186	ASCL2	18	19	37	1934.248
#187	HOXC8	18	16	34	2745.421
#188	E2F2	18	13	31	587.222
#189	ECSIT	18	19	37	1027.915
#190	PPBPL2	18	18	36	633.091
#191	VTN	18	16	34	1099.129
#192	MBD1	18	19	37	675.273
#193	HOXC10	18	21	39	944.264
#194	HOXA5	18	13	31	1095.643
#195	E2F1	18	15	33	908.985
#196	HIF3A	18	16	34	799.268
#197	MYOD1	18	16	34	1023.883
#198	HOXA6	18	17	35	1116.89
#199	FOSB	18	13	31	657.79
#200	PPARA	17	21	38	1896.681
#201	HOXB3	17	20	37	2283.411
#202	PPARG	17	20	37	573.086
#203	HOXD9	17	17	34	1117.576
#204	HEY2	17	21	38	1504.989
#205	GATA2	17	17	34	1185.825
#206	TBX3	17	18	35	592.576
#207	MYT1	17	25	42	1837.338
#208	TBX2	17	18	35	1478.889
#209	ZNF446	17	20	37	411.247
#210	FOSL1	16	15	31	1436.812
#211	ZNF93	16	21	37	895.615
#212	ZNF45	16	16	32	1617.356
#213	BCL11B	16	12	28	782.76
#214	KLF5	16	20	36	2144.517
#215	FOSL2	16	20	36	1093.435
#216	SOX5	16	19	35	1268.094
#217	NFAT5	16	17	33	454.737
#218	FOXL2	16	20	36	1514.382
#219	ZNF187	16	14	30	964.585
#220	ELF3	16	16	32	473.711
#221	RUNX2	16	19	35	774.14
#222	TFAP2C	16	26	42	1109.235
#223	ALX3	16	18	34	1678.412
#224	TBX6	16	25	41	1019.532
#225	HSF4	16	19	35	756.305
#226	ZBTB48	16	26	42	1339.071
#227	HOXD1	16	21	37	878.473
#228	E2F4	16	20	36	1207.764
#229	TADA2A	16	16	32	913.803
#230	PHF1	16	20	36	1160.992
#231	SALL1	15	20	35	1405.183
#232	THRA	15	19	34	724.517
#233	ZNF167	15	24	39	2004.394
#234	NKX3-1	15	17	32	792.258
#235	PCGF2	15	12	27	335.858
#236	SPIB	15	20	35	1007.798
#237	RB1	15	24	39	1341.719
#238	TFDP2	15	18	33	1261.187
#239	IKZF1	15	15	30	903.27
#240	SATB1	15	13	28	356.707
#241	PDX1	15	24	39	4352.226
#242	ZNF219	15	16	31	1455.853
#243	FOXD2	15	21	36	750.638
#244	HOXB6	15	15	30	515.774
#245	ZNF75D	15	17	32	1162.96
#246	BCL3	15	15	30	542.472
#247	NEUROG1	15	21	36	2349.338
#248	GATA1	15	18	33	960.149
#249	TRPS1	14	15	29	419.606
#250	NANOG	14	13	27	990.654
#251	FOXE3	14	19	33	1772.475
#252	POU6F1	14	24	38	1738.562
#253	NFX1	14	24	38	2150.529
#254	NR2F6	14	18	32	486.251
#255	TP53	14	22	36	881.737
#256	HOXA9	14	13	27	570.807
#257	SNAPC4	14	20	34	962.861
#258	PAX6	14	16	30	1076.403
#259	HOXA7	14	18	32	873.683
#260	ZSCAN18	14	25	39	1254.281
#261	ELF2	14	14	28	1289.995
#262	GATA6	13	18	31	876.619
#263	MSX1	13	17	30	597.811
#264	ZNF323	13	20	33	822.887
#265	SIM2	13	24	37	1238.895
#266	NR2E3	13	12	25	563.875
#267	ZFP37	13	21	34	599.96
#268	ZNF202	13	25	38	849.057
#269	OLIG2	13	22	35	1118.62
#270	LHX1	13	22	35	1502.441
#271	TSC22D2	13	23	36	937.01
#272	SUPT6H	13	19	32	870.427
#273	SOX17	13	26	39	1415.623
#274	ERG	13	16	29	791.231
#275	TSC22D3	13	18	31	587.898
#276	POU3F2	13	20	33	870.544
#277	NEUROD1	13	17	30	624.683
#278	DBP	13	23	36	1004.093
#279	ZNF155	13	19	32	667.387
#280	PRDM1	13	18	31	762.169
#281	EMX1	13	18	31	927.674
#282	BNC1	13	17	30	1074.507
#283	HOXB9	13	22	35	1654.345
#284	POU6F2	13	10	23	338.523
#285	YEATS4	13	17	30	556.612
#286	HOXD3	13	25	38	809.802
#287	LHX6	13	21	34	640.525
#288	PGR	13	18	31	573.669
#289	ZNF236	13	18	31	654.344
#290	SP1	12	23	35	1082.44
#291	SOX2	12	22	34	700.973
#292	STAT6	12	17	29	893.818
#293	PEG3	12	29	41	1987.79
#294	SIX3	12	20	32	671.258
#295	MLLT10	12	26	38	732.785
#296	PROX1	12	20	32	919.968
#297	ELK1	12	23	35	1341.593
#298	HR	12	19	31	883.577
#299	ZNF444	12	21	33	1271.721
#300	RXRB	12	18	30	1081.93
#301	SIX2	12	21	33	1363.684
#302	TCF7	12	18	30	617.13
#303	ZFP36L1	12	21	33	534.34
#304	BARX1	12	20	32	827.011
#305	ZNF154	12	20	32	1453.817
#306	C2orf3	12	21	33	1081.639
#307	ARID3A	12	20	32	951.388
#308	E2F8	12	17	29	733.978
#309	TCF12	12	19	31	839.86
#310	SIM1	12	19	31	966.372
#311	SOX11	12	24	36	996.659
#312	ZIC1	12	19	31	519.514
#313	FOXP3	11	18	29	937.042
#314	WNT5A	11	21	32	539.565
#315	DLX2	11	20	31	1105.953
#316	TEF	11	23	34	873.822
#317	HOXA1	11	19	30	323.734
#318	NR2E1	11	19	30	1591.668
#319	ZNF175	11	15	26	590.771
#320	NR0B1	11	26	37	1349.154
#321	IRX4	11	23	34	826.022
#322	FOXI1	11	27	38	1365.026
#323	TP63	11	22	33	2236.304
#324	NR1I2	11	19	30	694.948
#325	FOXB1	11	17	28	635.57
#326	KDM5B	11	27	38	743.395
#327	GSC2	11	20	31	1053.46
#328	NR3C2	11	12	23	503.097
#329	ESRRG	11	31	42	1666.498
#330	KLF4	11	16	27	776.26
#331	HOXC13	11	20	31	1028.606
#332	FOXH1	11	24	35	664.18
#333	SPI1	11	17	28	508.464
#334	PAX5	10	23	33	1180.118
#335	ZNF117	10	20	30	1026.383
#336	CITED1	10	20	30	1207.175
#337	TFAP2A	10	17	27	719.737
#338	CREBZF	10	20	30	529.499
#339	MSC	10	26	36	933.434
#340	ZNF135	10	29	39	717.554
#341	FOXE1	10	23	33	982.274
#342	HOXB7	10	19	29	752.308
#343	SCRT1	10	24	34	768.562
#344	SOX9	10	13	23	285.837
#345	MNX1	10	22	32	897.182
#346	PAX4	10	17	27	891.352
#347	ZNF41	10	28	38	1521.685
#348	ESRRB	10	18	28	691.133
#349	EHF	10	23	33	509.085
#350	SMAD6	10	21	31	406.51
#351	POU4F3	10	19	29	825.469
#352	ELK4	10	23	33	878.996
#353	TBX5	10	18	28	1415.115
#354	ZNF157	10	24	34	660.842
#355	PLAG1	10	21	31	1987.015
#356	IKZF3	10	23	33	2082.077
#357	VDR	10	28	38	2215.403
#358	HIC1	9	18	27	705.555
#359	SCML1	9	28	37	915.201
#360	ETV2	9	24	33	1002.928
#361	MLL	9	25	34	1398.258
#362	ZFHX3	9	21	30	483.952
#363	PAX8	9	24	33	947.711
#364	HNF4A	9	22	31	319.047
#365	NR4A1	9	22	31	604.108
#366	ARNT2	9	25	34	652.659
#367	MLXIPL	9	16	25	205.097
#368	HLF	9	30	39	748.924
#369	ETV4	9	19	28	671.117
#370	YY1	9	20	29	743.995
#371	ZNF3	9	26	35	1044.532
#372	MEOX1	9	20	29	599.723
#373	MYF6	9	18	27	931.329
#374	RCAN1	9	24	33	961.836
#375	BLZF1	9	17	26	540.062
#376	OVOL1	9	24	33	544.131
#377	ATF6B	9	20	29	625.589
#378	NFKB2	9	23	32	986.073
#379	HOXB1	8	20	28	772.285
#380	RUNX1	8	25	33	964.945
#381	HNF1A	8	17	25	855.095
#382	CRX	8	17	25	516.545
#383	ZNF238	8	20	28	1802.709
#384	ST18	8	16	24	827.714
#385	NKX3-2	8	21	29	575.406
#386	SATB2	8	24	32	702.221
#387	NFATC1	8	23	31	762.649
#388	NR2C1	8	21	29	683.752
#389	GBX2	8	21	29	709.335
#390	FOXA2	8	22	30	563.433
#391	CREB3L1	8	23	31	322.935
#392	CBFA2T2	8	21	29	1195.245
#393	HOXA2	8	21	29	836.19
#394	ZNF80	8	27	35	1007.524
#395	SMAD1	8	19	27	1049.555
#396	MEIS2	8	21	29	340.39
#397	HAND2	8	17	25	869.669
#398	ONECUT2	8	25	33	781.461
#399	HES1	8	18	26	789.748
#400	WT1	8	23	31	721.368
#401	MAFK	8	20	28	750.134
#402	MSRB2	7	23	30	699.515
#403	NKX2-5	7	23	30	550.989
#404	CREBBP	7	20	27	815.379
#405	RARB	7	19	26	505.15
#406	SMAD3	7	23	30	763.547
#407	NR5A2	7	18	25	258.384
#408	NPAS2	7	29	36	660.132
#409	DMRT1	7	26	33	617.653
#410	TBX19	7	17	24	954.499
#411	TLX3	7	21	28	724.37
#412	HOPX	7	25	32	636.894
#413	FOXC2	7	22	29	226.093
#414	HOXB8	7	22	29	733.18
#415	MEOX2	7	22	29	358.309
#416	C11orf9	7	25	32	770.272
#417	TRIM25	7	28	35	588.358
#418	NRL	7	18	25	433.787
#419	SOX30	7	29	36	1073.693
#420	ARNTL	7	22	29	299.63
#421	EGR4	7	19	26	725.454
#422	FOXD1	7	22	29	581.701
#423	ASCL1	7	23	30	510.37
#424	CSRNP3	7	23	30	578.417
#425	ESR2	7	24	31	794.917
#426	GCM1	7	17	24	353.412
#427	FOXD3	7	23	30	482.813
#428	ONECUT1	7	20	27	377.782
#429	PAX3	7	27	34	3137.678
#430	FOXJ1	7	20	27	433.224
#431	SLC26A3	7	25	32	654.958
#432	ZSCAN12	6	20	26	929.877
#433	LHX2	6	23	29	1894.542
#434	TLX2	6	20	26	627.997
#435	RARA	6	27	33	658.119
#436	TAF13	6	21	27	362.839
#437	LEF1	6	25	31	328.383
#438	CUX2	6	21	27	1096.437
#439	PITX1	6	28	34	705.92
#440	STAT2	6	11	17	118.026
#441	KLF12	6	22	28	679.119
#442	RXRA	6	20	26	491.255
#443	TBX1	6	27	33	677.364
#444	NPAS1	6	22	28	603.699
#445	EN2	6	20	26	388.646
#446	HNF4G	6	25	31	380.035
#447	HESX1	6	18	24	259.106
#448	DLX6	6	21	27	639.433
#449	NR4A2	6	27	33	325.848
#450	ZHX3	6	15	21	328.192
#451	SRY	5	21	26	431.996
#452	NKX2-8	5	17	22	314.876
#453	HMG20B	5	21	26	806.579
#454	SNAPC5	5	19	24	463.227
#455	USF2	5	23	28	265.018
#456	ZNF639	5	29	34	794.301
#457	FOXO3	5	24	29	414.916
#458	ATOH1	5	20	25	360.231
#459	HOXA10	5	21	26	830.487
#460	REST	5	24	29	539.821
#461	CREB5	5	18	23	300.128
#462	POU3F3	5	25	30	775.911
#463	POU1F1	5	23	28	758.907
#464	ZNF81	5	22	27	390.272
#465	ZNF134	5	19	24	382.203
#466	HOXB13	5	18	23	247.249
#467	MSX2	5	26	31	712.708
#468	MYCN	5	16	21	561.776
#469	SCAND2	5	23	28	830.714
#470	PRRX2	5	20	25	458.049
#471	NFATC4	5	22	27	594.539
#472	ELF4	5	25	30	327.954
#473	RFXAP	5	20	25	533.855
#474	ZNF287	5	22	27	204.674
#475	PTH	4	20	24	575.634
#476	IRF4	4	24	28	310.463
#477	MYF5	4	22	26	466.549
#478	ZNF165	4	29	33	362.588
#479	MEF2D	4	21	25	844.721
#480	POU2F2	4	21	25	430.727
#481	FOXO4	4	18	22	611.055
#482	RARG	4	22	26	649.876
#483	SRF	4	21	25	389.658
#484	PITX2	4	24	28	456.431
#485	HOXA3	4	21	25	396.592
#486	IRF5	4	22	26	590.744
#487	NR6A1	4	24	28	368.015
#488	PRDM2	4	25	29	357.048
#489	FOXG1	4	20	24	245.905
#490	TCF21	4	27	31	456.289
#491	PKNOX1	3	23	26	540.525
#492	RERE	3	19	22	353.24
#493	STRN3	3	20	23	440.792
#494	ZNF643	3	30	33	353.682
#495	SOX15	3	17	20	119.71
#496	SIX1	3	27	30	237.548
#497	TCF15	3	25	28	303.969
#498	POU2F3	2	27	29	301.408
#499	HOXD13	2	23	25	212.19
#500	CEBPE	2	24	26	182.647