Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	NFIB	61	5	66	1924.141
#2	SOX11	55	4	59	365.636
#3	PPARG	53	4	57	777.038
#4	ELF1	48	3	51	1238.779
#5	MAFF	47	10	57	4955.652
#6	JUNB	47	3	50	541.106
#7	PBX1	46	4	50	3377.956
#8	SIM1	45	2	47	58.662
#9	CSRNP3	44	2	46	345.156
#10	KLF4	44	10	54	1725.452
#11	ZNF135	43	7	50	354.3
#12	CEBPA	43	3	46	98.271
#13	TEAD3	42	3	45	679.119
#14	CITED1	41	5	46	256.391
#15	KDM5B	40	13	53	1114.323
#16	PBX3	40	7	47	449.601
#17	HMG20A	39	6	45	6570.148
#18	FOSL2	39	9	48	2447.801
#19	TCEAL1	38	6	44	2337.242
#20	HOXA9	37	8	45	2321.578
#21	ELF4	37	14	51	2406.616
#22	TCF4	37	14	51	2265.72
#23	SNAPC5	36	3	39	116.655
#24	NFAT5	36	2	38	47.624
#25	PTTG1	36	4	40	1384.537
#26	CREB5	35	3	38	615.029
#27	FUBP1	35	9	44	386.676
#28	TARDBP	35	5	40	738.643
#29	PEG3	35	10	45	1178.839
#30	BCL3	35	8	43	1136.185
#31	TCF3	34	13	47	4727.542
#32	ZNF500	34	6	40	955.038
#33	SALL2	34	9	43	3929.468
#34	BATF	33	4	37	461.092
#35	SIX1	33	12	45	390.544
#36	MTA1	33	12	45	986.408
#37	TP53	33	16	49	788.94
#38	ENO1	32	15	47	1239.156
#39	LEF1	32	9	41	1380.522
#40	HOPX	32	10	42	2647.809
#41	IRF8	32	9	41	836.737
#42	PAX6	32	14	46	1400.966
#43	FOXF1	31	9	40	3351.23
#44	BTG2	31	11	42	1040.966
#45	HOXA5	31	7	38	623.417
#46	VAV1	31	2	33	1917.632
#47	CEBPB	31	4	35	445.198
#48	STAT5B	30	12	42	1209.325
#49	ZNF167	30	10	40	954.999
#50	KLF9	30	10	40	548.303
#51	ELK3	30	15	45	2765.771
#52	TSC22D3	30	13	43	1175.352
#53	HCLS1	30	10	40	1205.503
#54	FOXC2	29	8	37	1176.304
#55	TGIF2	29	6	35	487.957
#56	MYC	29	13	42	843.764
#57	HOXA6	29	10	39	301.375
#58	MITF	29	14	43	2514.785
#59	MLX	28	13	41	1374.625
#60	RERE	28	15	43	1067.526
#61	MAFB	28	12	40	1769.453
#62	SMAD4	28	6	34	1267.075
#63	TFEC	28	3	31	194.147
#64	MEIS2	28	13	41	874.24
#65	NFYA	27	9	36	553.156
#66	DDIT3	27	15	42	1952.846
#67	TFAM	27	8	35	322.786
#68	FOXM1	27	7	34	1268.058
#69	NR2F2	26	11	37	1079.622
#70	MEF2C	26	8	34	742.35
#71	TRIM28	26	11	37	839.323
#72	ZNF207	26	13	39	1211.821
#73	KLF7	26	12	38	934.292
#74	RUNX1	26	9	35	275.399
#75	HOXB13	26	8	34	320.68
#76	TCF7L1	26	8	34	301.427
#77	PLAG1	25	8	33	1583.813
#78	EPAS1	25	16	41	1729.97
#79	NR3C2	25	11	36	2248.804
#80	TFE3	25	10	35	394.994
#81	TCF12	25	11	36	987.93
#82	NR1H3	24	11	35	1315.374
#83	BRD8	24	8	32	1196.029
#84	MEF2A	24	17	41	1983.444
#85	FOXF2	24	10	34	1693.169
#86	RARB	24	14	38	2291.305
#87	KLF6	24	13	37	712.994
#88	ZFHX3	24	13	37	807.179
#89	TADA3	24	10	34	616.194
#90	SPI1	24	6	30	1114.911
#91	ZNF148	24	7	31	840.75
#92	LHX2	24	16	40	1010.3
#93	MGA	23	15	38	1130.413
#94	GLI2	23	16	39	1210.117
#95	ZSCAN18	23	14	37	4042.808
#96	HMG20B	23	21	44	2007.878
#97	GATA3	23	7	30	942.186
#98	NCOR1	23	19	42	2616.652
#99	RB1	23	8	31	693.12
#100	CREBL2	23	14	37	924.896
#101	TCF25	23	9	32	1007.978
#102	ELF5	22	8	30	512.248
#103	FLI1	22	9	31	1443.516
#104	GAS7	22	11	33	1066.133
#105	TEAD1	22	11	33	2754.28
#106	YY1	22	6	28	1377.881
#107	ELF2	22	10	32	4541.602
#108	STAT5A	22	7	29	1348.369
#109	SOX18	22	9	31	1429.34
#110	FOXN3	21	16	37	3321.551
#111	IKZF1	21	4	25	134.213
#112	RXRA	21	8	29	1169.213
#113	DRAP1	21	16	37	1226.209
#114	PCGF2	21	15	36	958.764
#115	SP140	21	8	29	895.611
#116	BHLHE40	21	12	33	872.962
#117	NR4A2	21	5	26	284.197
#118	ATF2	20	9	29	359.475
#119	HSF2	20	11	31	3001.934
#120	ZNF75D	20	17	37	2327.083
#121	SOX17	20	16	36	932.744
#122	E2F8	20	11	31	1947.445
#123	KLF2	20	11	31	1047.934
#124	RELB	20	9	29	523.019
#125	ZNF3	20	12	32	472.408
#126	RCOR1	20	12	32	971.695
#127	HEY1	19	10	29	904.126
#128	REST	19	7	26	974.112
#129	MEIS1	19	14	33	1063.597
#130	TRIM22	19	22	41	2920.595
#131	MSRB2	19	21	40	2044.751
#132	VDR	19	18	37	1137.686
#133	ZNF93	19	14	33	1269.032
#134	RBPJ	19	11	30	868.373
#135	IRF4	19	10	29	477.516
#136	SMAD3	18	10	28	1980.364
#137	HNRNPK	18	13	31	786.118
#138	THRA	18	9	27	789.055
#139	ATF3	18	6	24	526.159
#140	NR1H2	18	16	34	2793.745
#141	NFIL3	18	8	26	313.957
#142	HLF	18	13	31	1019.431
#143	HMGB2	18	10	28	638.489
#144	GABPA	18	13	31	1057.305
#145	AR	18	14	32	820.805
#146	FOSL1	18	19	37	2535.722
#147	DMTF1	18	10	28	1478.95
#148	SOX12	18	14	32	759.24
#149	NR2F6	18	16	34	701.638
#150	REL	18	11	29	2307.302
#151	SRF	18	5	23	188.144
#152	ZKSCAN1	18	11	29	562.693
#153	HIC1	17	18	35	1801.921
#154	ZNF236	17	11	28	1175.949
#155	SOX13	17	15	32	2551.751
#156	ETS2	17	10	27	1236.068
#157	FOSB	17	9	26	877.171
#158	CNBP	17	17	34	2285.93
#159	ZNF238	17	24	41	2916.615
#160	ELK1	17	17	34	1434.314
#161	ADNP	17	15	32	780.588
#162	HMGA1	17	15	32	2068.918
#163	NR4A1	17	6	23	216.897
#164	ATF4	17	11	28	670.644
#165	NFKB1	17	16	33	605.041
#166	NR4A3	17	8	25	405.723
#167	HOXA1	17	15	32	3406.756
#168	GATAD2A	17	14	31	2967.981
#169	FOXD2	16	8	24	1081.488
#170	ZNF202	16	18	34	1467.517
#171	PPARD	16	15	31	793.765
#172	STAT6	16	23	39	3462.655
#173	WNT5A	16	28	44	8211.298
#174	MLXIPL	16	12	28	687.363
#175	PRDM2	16	18	34	2345.1
#176	LMO4	16	12	28	492.536
#177	HNRNPAB	16	19	35	2183.629
#178	CREBZF	16	10	26	964.273
#179	RUNX1T1	16	14	30	1946.431
#180	ZNF91	16	14	30	1597.028
#181	MSX2	16	12	28	1668.856
#182	SNAI2	16	20	36	1769.266
#183	FOXJ3	16	10	26	1436.691
#184	HIF3A	15	14	29	954.05
#185	CEBPD	15	10	25	315.914
#186	MMP14	15	20	35	2299.386
#187	GCFC1	15	12	27	485.796
#188	PRDM1	15	10	25	1913.515
#189	ZHX2	15	12	27	721.67
#190	ZBTB38	15	15	30	473.417
#191	ZNF117	15	12	27	1045.089
#192	POU2F2	15	7	22	725.779
#193	CREB3L1	15	21	36	4535.258
#194	E4F1	15	15	30	665.193
#195	BATF3	15	21	36	2073.327
#196	STAT3	15	17	32	1153.249
#197	CREB3	15	16	31	1036.929
#198	PRRX1	15	12	27	676.536
#199	RXRG	15	14	29	536.329
#200	STAT4	14	7	21	301.379
#201	IRF1	14	11	25	1092.506
#202	TCF7L2	14	16	30	534.3
#203	BCL6	14	9	23	1259.244
#204	CNOT8	14	14	28	1367.708
#205	MLLT10	14	11	25	533.15
#206	SCMH1	14	14	28	773.108
#207	ESR1	14	13	27	1887.882
#208	YEATS4	14	15	29	666.981
#209	FOXE1	14	6	20	980.558
#210	SOX4	14	26	40	1720.807
#211	STAT1	14	6	20	147.129
#212	HOXA10	14	14	28	825.343
#213	ZFHX4	14	15	29	1803.338
#214	NKX3-2	14	20	34	1223.503
#215	CITED2	14	19	33	1907.523
#216	TFCP2	14	13	27	1121.088
#217	HOXA4	14	10	24	267.369
#218	SMAD5	14	13	27	1056.123
#219	PHTF1	14	10	24	581.74
#220	CBFB	14	22	36	1751.621
#221	KDM5A	14	13	27	647.505
#222	HMGB1	14	12	26	513.988
#223	ZIC3	14	14	28	918.936
#224	SPEN	14	6	20	594.125
#225	E2F5	14	16	30	2323.875
#226	GTF2IRD1	14	11	25	3249.014
#227	NOLC1	14	16	30	1282.005
#228	RFXANK	14	20	34	861.724
#229	GTF2I	13	11	24	919.16
#230	HEY2	13	15	28	1014.539
#231	ZEB2	13	12	25	554.549
#232	ZNF217	13	22	35	2860.526
#233	NFIX	13	19	32	1477.652
#234	GATAD1	13	11	24	432.149
#235	TSHZ2	13	16	29	1615.96
#236	MNT	13	14	27	1263.388
#237	KLF3	13	15	28	2121.867
#238	NFE2L3	13	16	29	1581.318
#239	ZNF193	13	15	28	879.96
#240	SP3	12	17	29	1099.569
#241	ZNF85	12	18	30	1006.834
#242	NFKB2	12	8	20	184.998
#243	ETV1	12	22	34	1361.823
#244	E2F1	12	14	26	832.784
#245	FOXL2	12	12	24	688.939
#246	FOXC1	12	16	28	8241.381
#247	TFDP1	12	17	29	587.498
#248	VTN	12	12	24	1532.097
#249	SOX15	12	10	22	936.432
#250	NFE2L1	12	14	26	373.353
#251	MYBL2	12	10	22	668.699
#252	FOS	12	9	21	562.32
#253	BCL11B	12	13	25	470.848
#254	CNOT7	12	14	26	357.111
#255	HOXC13	12	12	24	3723.226
#256	ZNF45	12	21	33	1577.843
#257	MZF1	12	14	26	727.944
#258	FOXO1	12	14	26	1332.629
#259	ZNF394	12	12	24	1858.023
#260	BACH2	12	17	29	1362.313
#261	TFAP2C	12	16	28	641.665
#262	ZBTB17	12	14	26	1293.855
#263	RFX5	11	14	25	1019.329
#264	PRRX2	11	16	27	1540.253
#265	HOXA11	11	13	24	1763.738
#266	BHLHE41	11	14	25	417.822
#267	FOXK2	11	16	27	2676.277
#268	TCF15	11	9	20	881.181
#269	NR3C1	11	20	31	838.25
#270	ECSIT	11	19	30	1073.693
#271	HOXC8	11	13	24	815.63
#272	JUND	11	15	26	621.246
#273	ZNF281	11	20	31	1065.905
#274	CREM	11	11	22	706.453
#275	IRF6	11	16	27	1716.063
#276	TBX1	11	12	23	569.343
#277	E2F3	11	20	31	1534.766
#278	C2orf3	11	14	25	187.318
#279	ARNTL2	10	17	27	1431.417
#280	PLSCR1	10	23	33	931.973
#281	STAT2	10	17	27	1107.319
#282	ZIC1	10	26	36	1164.721
#283	TAF12	10	15	25	473.787
#284	HOXB5	10	8	18	128.006
#285	HOXB6	10	16	26	1282.789
#286	MLL	10	13	23	558.524
#287	NKX3-1	10	11	21	203.341
#288	HIF1A	10	24	34	2897.166
#289	EGR1	10	5	15	61.618
#290	GTF2H3	10	16	26	1669.55
#291	SUPT6H	10	16	26	513.357
#292	MEOX1	10	20	30	2424.135
#293	RUNX3	10	19	29	2521.947
#294	CTNNB1	10	18	28	1660.213
#295	IRF3	10	12	22	957.479
#296	ZBTB48	10	13	23	436.387
#297	XBP1	10	15	25	579.577
#298	SLC30A9	10	12	22	766.321
#299	SATB1	10	23	33	2761.263
#300	HOXD3	10	18	28	1659.969
#301	NFYC	10	20	30	1138.144
#302	CTCF	10	12	22	2215.728
#303	SMAD1	10	26	36	2167.789
#304	SMAD6	10	20	30	917.016
#305	SREBF1	9	18	27	1278.051
#306	TFDP2	9	15	24	1131.325
#307	HOXC4	9	25	34	2596.037
#308	HOXD11	9	19	28	1063.381
#309	NR1D2	9	15	24	708.315
#310	LZTS1	9	14	23	545.854
#311	TBX2	9	18	27	1183.452
#312	SUPT4H1	9	18	27	1175.039
#313	TAF4	9	14	23	466.864
#314	TBX3	9	19	28	947.036
#315	SALL1	9	15	24	959.849
#316	MAF	9	23	32	926.276
#317	GABPB1	9	17	26	1318.528
#318	AFF1	9	24	33	822.367
#319	USF2	9	25	34	1653.156
#320	GTF2H4	9	18	27	1256.488
#321	NR5A2	9	12	21	377.801
#322	AATF	9	22	31	1169.137
#323	ETV5	9	17	26	524.517
#324	MSC	9	20	29	2135.158
#325	TBX5	9	12	21	123.14
#326	ZNF83	9	17	26	1663.902
#327	TSC22D4	9	12	21	862.286
#328	TEAD4	9	16	25	711.356
#329	CDKN2A	9	18	27	412.542
#330	HDAC2	9	17	26	728.935
#331	YBX1	9	17	26	1584.277
#332	STRN3	9	16	25	1899.28
#333	ERG	8	13	21	759.959
#334	PA2G4	8	16	24	471.551
#335	PKNOX2	8	18	26	710.507
#336	HDAC1	8	23	31	1032.949
#337	HMBOX1	8	16	24	230.477
#338	SNAPC4	8	20	28	944.827
#339	HOXB7	8	15	23	891.851
#340	SCML1	8	17	25	613.942
#341	IRF2	8	16	24	766.469
#342	TP63	8	21	29	1173.212
#343	LASS2	8	18	26	532.498
#344	CSDA	8	17	25	703.732
#345	EN1	8	19	27	512.058
#346	DLX4	8	15	23	1463.388
#347	ZFP36L2	8	19	27	809.776
#348	DBP	8	17	25	1039.931
#349	TAF5	8	17	25	864.46
#350	ATF5	8	20	28	829.678
#351	WT1	8	15	23	1795.1
#352	CSRNP2	8	13	21	1802.347
#353	JUN	8	15	23	240.767
#354	RELA	8	13	21	535.311
#355	ETV6	8	20	28	810.064
#356	MEOX2	8	28	36	2867.935
#357	CBFA2T2	8	20	28	2024.369
#358	TAF6	8	21	29	1453.545
#359	IRF9	8	10	18	833.859
#360	CREB3L2	8	13	21	643.363
#361	FBXW7	7	17	24	1144.43
#362	ZXDC	7	18	25	811.57
#363	RNF4	7	19	26	1005.358
#364	ZNF131	7	15	22	821.611
#365	RCAN1	7	21	28	521.382
#366	BACH1	7	19	26	807.026
#367	EGR3	7	13	20	141.557
#368	SIX2	7	20	27	502.022
#369	TSC22D1	7	22	29	389.713
#370	MSL3	7	19	26	2348.202
#371	EGR2	7	14	21	2193.052
#372	EDF1	7	15	22	571.864
#373	ZNF268	7	13	20	434.429
#374	FOXG1	7	26	33	1830.886
#375	LZTR1	7	16	23	841.14
#376	PITX2	7	13	20	991.945
#377	TWIST1	7	29	36	1545.632
#378	ARNT2	7	19	26	565.727
#379	SIM2	7	12	19	494.807
#380	ZFP36L1	7	22	29	1606.987
#381	NR2C1	7	20	27	2007.098
#382	ZEB1	7	17	24	264.945
#383	CLOCK	7	18	25	1027.518
#384	HHEX	7	21	28	466.364
#385	ZNF133	7	18	25	721.6
#386	PKNOX1	7	21	28	1126.116
#387	TGIF1	7	29	36	1233.47
#388	TRPS1	7	13	20	367.002
#389	CUX2	7	7	14	468.985
#390	HMGA2	6	20	26	3054.495
#391	NPAT	6	14	20	808.832
#392	ZNF140	6	15	21	402.068
#393	RORA	6	20	26	874.9
#394	KLF12	6	18	24	698.792
#395	IRF7	6	9	15	361.877
#396	ADNP2	6	18	24	1140.246
#397	ALX1	6	20	26	2274.445
#398	ZFPM2	6	23	29	816.18
#399	BUD31	6	17	23	1215.578
#400	AHR	6	26	32	806.956
#401	NFIC	6	19	25	666.122
#402	UBP1	6	20	26	1004.793
#403	TFEB	6	20	26	611.027
#404	SREBF2	6	18	24	1447.918
#405	TCF21	6	24	30	749.11
#406	ESRRG	6	13	19	498.111
#407	NFX1	6	20	26	1806.154
#408	SPIB	6	14	20	508.56
#409	HOXD4	6	18	24	818.512
#410	SCML2	6	11	17	472.811
#411	ZNF274	6	23	29	1205.638
#412	PHF1	6	22	28	1889.482
#413	KLF11	6	13	19	631.935
#414	NOTCH1	6	14	20	377.946
#415	IRX5	6	18	24	468.997
#416	ZGPAT	6	21	27	893.97
#417	ATF1	6	21	27	1296.61
#418	POU2F1	5	18	23	503.391
#419	HOXD9	5	18	23	568.627
#420	NFATC1	5	21	26	1414.881
#421	MECOM	5	14	19	206.958
#422	GATA6	5	21	26	726.898
#423	LHX6	5	16	21	241.593
#424	MYF6	5	11	16	902.809
#425	HOXD10	5	16	21	323.203
#426	EN2	5	10	15	311.845
#427	NFYB	5	21	26	1844.166
#428	NR1H4	5	13	18	247.581
#429	CUX1	5	16	21	544.595
#430	KLF10	5	15	20	359.386
#431	CREBBP	5	19	24	530.721
#432	ZNF189	5	14	19	479.283
#433	TCFL5	5	25	30	1198.622
#434	TFAP2A	5	17	22	1481.846
#435	SLC2A4RG	5	18	23	431.525
#436	AHCTF1	5	21	26	1898.724
#437	ZHX3	5	20	25	207.873
#438	MEIS3P1	5	20	25	313.215
#439	SOLH	5	21	26	562.524
#440	RARA	4	23	27	792.496
#441	SCAND1	4	18	22	624.005
#442	IRF5	4	16	20	211.166
#443	IRX4	4	11	15	491.752
#444	TCF20	4	20	24	1577.749
#445	KLF5	4	16	20	1679.196
#446	FOXO3	4	15	19	266.043
#447	SOX2	4	15	19	1521.387
#448	E2F6	4	16	20	405.598
#449	GATA2	4	18	22	1007.247
#450	UBN1	4	16	20	392.521
#451	TAF10	4	15	19	568.283
#452	MAX	4	14	18	502.37
#453	ARNTL	3	18	21	295.787
#454	POU4F1	3	7	10	125.941
#455	LASS6	3	22	25	1109.267
#456	NFATC4	3	24	27	629.767
#457	HOXC11	3	17	20	182.608
#458	ERF	3	17	20	172.241
#459	HOXB2	3	23	26	342.465
#460	ZNF24	3	15	18	86.621
#461	NR2F1	3	22	25	265.441
#462	ARNT	3	15	18	329.53
#463	CIR1	3	18	21	307.157
#464	SIX3	3	14	17	329.518
#465	FOXJ2	3	19	22	316.794
#466	HES1	3	23	26	939.696
#467	SATB2	3	26	29	338.825
#468	TSC22D2	3	20	23	83.054
#469	PURA	3	24	27	945.78
#470	CREB1	3	15	18	196.174
#471	GLI3	3	21	24	546.537
#472	ATF6	2	22	24	387.43
#473	NFATC3	2	15	17	109.369
#474	BTAF1	2	17	19	401.286
#475	HSF1	2	19	21	122.019
#476	HOXC10	2	18	20	389.425
#477	AEBP1	2	26	28	207.261
#478	PITX1	2	20	22	357.575
#479	SMAD2	2	22	24	284.832
#480	TULP4	2	20	22	180.445
#481	ZNF323	2	23	25	338.825
#482	CTBP1	2	21	23	437.613
#483	TBP	2	14	16	418.345
#484	ISL1	2	14	16	267.579
#485	PBX2	2	24	26	850.851
#486	MSX1	2	20	22	333.794
#487	FOXD1	2	27	29	167.01
#488	HIRA	2	22	24	321.161
#489	NFE2L2	2	20	22	276.295
#490	ASCL1	2	11	13	368.921
#491	TCF7	2	18	20	264.118
#492	SOX9	2	31	33	230.937
#493	C11orf9	2	15	17	403.226
#494	NPAS2	1	28	29	185.586
#495	TAF7	1	18	19	52.428
#496	RBCK1	1	19	20	55.999
#497	MAFG	1	23	24	111.104
#498	ZNF277	1	15	16	118.538
#499	ZNF232	1	22	23	381.995
#500	NFE2	0	13	13	0