Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TCF21	55	4	59	561.606
#2	ERG	53	3	56	113.073
#3	SOX7	51	5	56	1353.017
#4	KLF3	46	4	50	182.246
#5	UHRF1	45	5	50	3153.552
#6	TFCP2	45	7	52	1249.971
#7	CREB3L4	45	6	51	795.267
#8	ATF1	43	0	43	0
#9	ZEB2	41	9	50	4307.22
#10	NKX1-1	41	2	43	769.861
#11	TAL1	39	1	40	41.722
#12	ZFPM2	39	3	42	6550.293
#13	ZNF438	37	4	41	224.344
#14	MAFF	37	6	43	861.598
#15	SOX17	36	3	39	477.962
#16	TAF12	36	12	48	2186.868
#17	MTA3	35	7	42	768.741
#18	RXRB	34	5	39	175.591
#19	KLF12	33	8	41	1449.48
#20	NFIL3	33	4	37	1107.835
#21	MAX	33	5	38	5068.885
#22	FOXM1	33	5	38	415.501
#23	SMAD4	32	5	37	5193.711
#24	NFYB	32	3	35	198.126
#25	PKNOX2	32	7	39	513.152
#26	NFYC	32	6	38	315.473
#27	TFE3	32	6	38	175.162
#28	FOXF1	32	3	35	530.105
#29	PRDM2	32	8	40	724.008
#30	HCLS1	32	8	40	3825.682
#31	KLF9	32	8	40	9356.042
#32	E2F5	31	7	38	850.556
#33	TFAP2A	31	11	42	1776.897
#34	CBFB	30	4	34	3108.315
#35	EPAS1	30	5	35	10088.436
#36	E2F8	30	14	44	751.235
#37	MLX	30	10	40	1004.574
#38	PCGF6	29	8	37	1589.946
#39	ELK1	29	1	30	3.709
#40	ZFP36L2	29	8	37	3396.701
#41	PEG3	29	13	42	12349.017
#42	TCF4	29	10	39	1066.357
#43	SMAD9	29	10	39	4161.969
#44	MITF	29	13	42	3836.264
#45	ZNF277	29	7	36	717.302
#46	HNF4G	29	12	41	12154.098
#47	KLF2	29	9	38	418.977
#48	TFDP1	28	9	37	1294.325
#49	HES6	28	13	41	2195.658
#50	TBX2	27	6	33	175.444
#51	BCL3	27	11	38	1436.082
#52	NR2F2	27	8	35	1111.611
#53	ZNF131	27	1	28	29.899
#54	RORA	27	6	33	820.326
#55	TCF19	27	8	35	154.126
#56	GTF2I	26	4	30	1675.746
#57	NFIX	26	8	34	1514.3
#58	NFXL1	26	13	39	4917.989
#59	FOXP4	26	8	34	3895.542
#60	STAT1	26	7	33	1004.347
#61	PTTG1	26	12	38	862.022
#62	ZNF41	26	10	36	2760.274
#63	MYBL2	26	9	35	1901.886
#64	MZF1	25	12	37	1854.445
#65	RB1	25	9	34	1318.613
#66	CNBP	25	15	40	6898.67
#67	BACH1	25	11	36	872.249
#68	CEBPD	25	11	36	5649.139
#69	ATF3	24	3	27	261.466
#70	TBX5	24	7	31	199.354
#71	CREBL2	24	11	35	1418.38
#72	TFEC	24	14	38	4057.043
#73	SIX4	24	8	32	1680.929
#74	CBFA2T3	24	4	28	1791.468
#75	TBX3	24	7	31	745.519
#76	E2F7	23	6	29	412.855
#77	NKX2-1	23	11	34	2814.101
#78	TCF25	23	8	31	2874.877
#79	TSHZ3	23	7	30	568.798
#80	CREM	23	4	27	195.486
#81	EBF1	23	12	35	1865.905
#82	ETV4	22	17	39	7263.317
#83	ENO1	22	11	33	1077.794
#84	ATF7	22	6	28	917.222
#85	GTF2H3	22	11	33	2550.107
#86	FLI1	22	8	30	1895.033
#87	IKZF1	22	1	23	11.863
#88	FOSB	22	6	28	329.779
#89	MESP1	22	15	37	1645.47
#90	SOX21	22	5	27	896.312
#91	BCL6	22	7	29	451.032
#92	RCAN1	21	9	30	1069.865
#93	STAT2	21	16	37	3019.112
#94	ADNP	21	8	29	2722.314
#95	ZFPM1	21	14	35	5701.011
#96	ZNF367	21	11	32	1817.871
#97	SP1	21	6	27	93.181
#98	SOX4	20	14	34	1208.913
#99	DLX2	20	4	24	79.263
#100	HOXA10	20	13	33	1315.284
#101	IRF6	20	14	34	2092.994
#102	KLF4	20	14	34	3454.258
#103	KLF11	20	7	27	376.21
#104	CSRNP1	20	5	25	3203.304
#105	HOPX	20	19	39	4057.332
#106	TCF7L2	20	8	28	1605.906
#107	STAT6	20	10	30	754.059
#108	FOSL1	20	9	29	457.244
#109	SPDEF	20	14	34	607.879
#110	ZSCAN16	20	12	32	3276.872
#111	MSX1	20	9	29	164.407
#112	MAFB	20	11	31	3705.103
#113	MYC	19	11	30	336.556
#114	NR3C1	19	9	28	1828.725
#115	GABPA	19	6	25	362.773
#116	IRX2	19	19	38	5968.711
#117	YBX1	19	8	27	3528.652
#118	FOSL2	19	10	29	1971.247
#119	PHTF1	19	6	25	728.02
#120	FOXK2	19	10	29	1221.687
#121	TAF1B	19	15	34	3454.446
#122	ETV5	18	6	24	1992.711
#123	HMGA1	18	14	32	752.912
#124	SNAI2	18	18	36	2513.898
#125	C5orf41	18	7	25	323.21
#126	FOXO6	18	11	29	1202.213
#127	FOXO1	18	12	30	545.394
#128	ZNF45	18	9	27	557.614
#129	ZHX2	18	10	28	1898.816
#130	GATA6	18	22	40	3136.277
#131	HNF1B	18	13	31	2029.604
#132	ELF2	18	10	28	1162.951
#133	ZNF217	18	13	31	1050.129
#134	RERE	18	9	27	917.184
#135	RFXAP	17	13	30	1929.826
#136	HMGA2	17	15	32	2439.147
#137	CBFA2T2	17	11	28	1638.681
#138	KLF6	17	14	31	1690.035
#139	HOXB7	17	14	31	1566.141
#140	FOXP1	17	6	23	3629.983
#141	CNOT7	17	12	29	1089.681
#142	ETS2	17	12	29	937.284
#143	CSDA	17	9	26	964.85
#144	ZNF19	17	13	30	1611.508
#145	BLZF1	17	12	29	1549.863
#146	SIN3A	17	13	30	2368.212
#147	GSX1	17	6	23	437.587
#148	STAT5B	17	10	27	1799.759
#149	TRPS1	16	14	30	1125.916
#150	PITX1	16	13	29	594.467
#151	SLC30A9	16	19	35	4296.565
#152	MEOX2	16	11	27	842.331
#153	CREB1	16	8	24	154.895
#154	ZNF92	16	15	31	2634.762
#155	AFF4	16	6	22	1238.372
#156	SUPT6H	16	8	24	845.849
#157	TCEAL1	16	12	28	1324.318
#158	RELA	16	13	29	1758.446
#159	CNOT8	16	12	28	2923.498
#160	IRF8	16	8	24	857.248
#161	TCF7	16	11	27	5208.265
#162	NR4A3	16	9	25	1187.327
#163	BATF3	16	8	24	467.763
#164	HOXB9	16	10	26	2953.164
#165	TEAD4	16	13	29	822.401
#166	ZBTB38	16	7	23	440.558
#167	FOXA2	16	20	36	2845.219
#168	MEIS2	15	19	34	4068.201
#169	TSHZ1	15	18	33	4915.477
#170	TAF5	15	7	22	842.339
#171	NFE2L2	15	9	24	835.112
#172	GATA2	15	9	24	237.424
#173	SIX1	15	12	27	401.186
#174	RARA	15	12	27	754.723
#175	ARNT	15	6	21	55.703
#176	PLSCR1	15	13	28	3557.736
#177	PCGF2	15	15	30	2073.005
#178	MNX1	15	16	31	1175.266
#179	STRN3	14	17	31	1143.626
#180	MLLT10	14	8	22	702.35
#181	SOX11	14	16	30	1488.438
#182	MSRB2	14	9	23	1146.895
#183	FOXO3	14	9	23	2458.236
#184	ZGPAT	14	18	32	3001.111
#185	ZNF148	14	14	28	3739.358
#186	GABPB1	14	18	32	1953.281
#187	TLX3	14	8	22	1967.672
#188	NFIC	14	10	24	3084.563
#189	ZHX3	14	13	27	361.66
#190	SMAD2	14	10	24	1481.353
#191	ZNF274	14	9	23	1257.611
#192	MAFK	14	9	23	2669.064
#193	GLIS3	13	15	28	1088.335
#194	ARNTL2	13	15	28	1997.534
#195	SATB2	13	18	31	8503.093
#196	SALL2	13	10	23	1046.781
#197	TFAP2C	13	19	32	3533.434
#198	TSC22D3	13	8	21	1108.776
#199	NFE2L3	13	12	25	2041.468
#200	ZHX1	13	13	26	2718.284
#201	HOXD1	13	20	33	1643.321
#202	VDR	13	13	26	625.645
#203	FOXN3	13	15	28	1472.78
#204	NR2F1	13	10	23	225.765
#205	AHCTF1	13	11	24	936.806
#206	ZEB1	12	10	22	536.896
#207	NPAT	12	11	23	247.887
#208	NR4A1	12	7	19	2068.349
#209	NKX3-1	12	14	26	661.974
#210	TCF12	12	7	19	1452.547
#211	HOXB8	12	8	20	805.338
#212	NR2C2	12	13	25	523.804
#213	ZNF207	12	13	25	442.899
#214	CREBZF	12	13	25	1443.654
#215	CCRN4L	12	9	21	1471.537
#216	KLF10	12	7	19	425.257
#217	SMAD6	12	9	21	148.003
#218	IRX3	12	23	35	1344.798
#219	PGR	12	11	23	448.129
#220	RUNX3	11	15	26	1120.455
#221	SP140	11	8	19	354.063
#222	FOXQ1	11	23	34	2547.874
#223	SMAD3	11	12	23	596.355
#224	IRF1	11	13	24	1228.317
#225	HDAC1	11	11	22	7873.093
#226	REST	11	5	16	346.057
#227	HMG20B	11	8	19	1695.921
#228	KLF7	11	10	21	2028.751
#229	RORC	11	18	29	968.44
#230	HOXC10	11	15	26	1710.599
#231	NR3C2	11	16	27	1507.938
#232	ETV1	11	12	23	13181.625
#233	HSF2	11	15	26	619.769
#234	LEF1	11	22	33	1971.973
#235	FOXF2	11	12	23	111.911
#236	OVOL1	11	12	23	4655.272
#237	C11orf9	11	17	28	591.233
#238	YEATS4	11	16	27	8526.753
#239	HOXA5	11	12	23	415.713
#240	TSC22D2	11	12	23	1694.855
#241	JUND	10	12	22	3439.312
#242	KDM5B	10	18	28	1020.554
#243	DBP	10	12	22	857.205
#244	TWIST2	10	27	37	4081.392
#245	RELB	10	11	21	796.707
#246	SOX6	10	13	23	4174.329
#247	ZNF138	10	14	24	622.949
#248	TRIM29	10	15	25	3168.093
#249	EGR3	10	10	20	200.268
#250	HOXC12	10	9	19	3486.14
#251	ZNF639	10	15	25	2275.191
#252	CITED2	10	23	33	16579.38
#253	ESR1	10	20	30	3933.568
#254	GLI3	10	15	25	2559.663
#255	MBD1	10	13	23	303.27
#256	MEF2A	10	9	19	1638.057
#257	ZNF70	10	16	26	1435.94
#258	DLX4	10	16	26	1160.105
#259	GAS7	10	15	25	2457.301
#260	TCF3	9	15	24	1402.274
#261	MSC	9	20	29	1736.719
#262	SLC2A4RG	9	13	22	2834.911
#263	NR4A2	9	9	18	136.749
#264	ZNF281	9	16	25	424.349
#265	TRIM25	9	20	29	2279.879
#266	TP53	9	12	21	278.535
#267	HOXA2	9	16	25	3776.777
#268	BACH2	9	16	25	1077.595
#269	GRHL2	9	16	25	815.145
#270	TBX15	9	21	30	1029.469
#271	CTNNB1	9	10	19	2717.306
#272	TEAD3	9	16	25	1392.189
#273	ATF2	9	8	17	160.956
#274	ZXDC	9	16	25	3785.758
#275	EHF	9	16	25	3437.014
#276	CREB5	9	20	29	2188.934
#277	RUNX1	8	11	19	552.739
#278	TSC22D4	8	14	22	3832.879
#279	HHEX	8	13	21	179.986
#280	LZTS1	8	11	19	662.426
#281	PBX1	8	19	27	5577.918
#282	IKZF4	8	13	21	1460.859
#283	HOXB2	8	18	26	2789.929
#284	TFAP2D	8	15	23	1794.299
#285	FOS	8	11	19	844.362
#286	GATA3	8	17	25	4244.47
#287	ARX	8	17	25	1050.493
#288	FOXA3	8	12	20	1341.651
#289	ZNF397	8	16	24	943.957
#290	TULP4	8	10	18	919.171
#291	KLF5	8	12	20	2159.145
#292	TARDBP	8	12	20	2868.991
#293	FOXD1	8	11	19	745.506
#294	PRDM1	8	20	28	1021.273
#295	NFATC2	8	15	23	976.173
#296	DLX3	8	20	28	746.863
#297	VAV1	8	11	19	1070.643
#298	FOXC2	8	15	23	980.873
#299	HOXB3	8	14	22	1372.644
#300	MMP14	8	16	24	1749.145
#301	HIC1	8	19	27	1247.109
#302	SCAND3	8	19	27	2169.931
#303	NFKB2	8	11	19	1099.467
#304	ZIC2	8	11	19	332.703
#305	ELK3	8	15	23	225.528
#306	HSF1	8	10	18	1828.686
#307	TCF7L1	8	23	31	3748.23
#308	FOXJ3	8	9	17	121.085
#309	SCML1	7	17	24	1111.052
#310	ISL1	7	11	18	2173.004
#311	ZNF33B	7	14	21	2490.774
#312	ZFP90	7	15	22	563.305
#313	FOXP2	7	17	24	461.057
#314	MYCL1	7	18	25	684.442
#315	HOXB6	7	19	26	1945.201
#316	MGA	7	10	17	162.846
#317	NFIB	7	17	24	474.735
#318	WNT5A	7	13	20	722.27
#319	ZNF93	7	21	28	1679.918
#320	NR5A2	7	15	22	140.147
#321	CSRNP3	7	16	23	400.798
#322	NR1H3	7	8	15	508.776
#323	GLIS2	7	16	23	1294.824
#324	NR2C1	7	12	19	638.571
#325	HEY2	7	16	23	381.929
#326	HOXC9	7	14	21	1655.434
#327	PITX2	7	11	18	1456.82
#328	NOLC1	7	10	17	803.505
#329	LHX6	7	13	20	717.255
#330	STAT3	7	16	23	606.448
#331	EGR2	7	20	27	649.415
#332	SOX2	7	17	24	2116.913
#333	HOXA3	7	11	18	1855.345
#334	LASS6	7	13	20	3458.505
#335	E2F3	7	15	22	1408.065
#336	HMGB1	7	11	18	580.311
#337	NFAT5	7	8	15	2422.908
#338	NFATC1	7	15	22	578.609
#339	SATB1	7	16	23	4349.464
#340	BHLHE41	7	19	26	1097.961
#341	SOX9	7	20	27	3026.95
#342	MECOM	7	17	24	1207.53
#343	THRB	7	20	27	732.861
#344	HMBOX1	7	19	26	1168.568
#345	ZNF24	7	9	16	93.085
#346	FUBP1	7	17	24	2482.667
#347	TFAM	7	20	27	2885.519
#348	ARID4A	6	13	19	641.494
#349	IRX5	6	18	24	574.362
#350	SPI1	6	14	20	3608.811
#351	ONECUT2	6	13	19	1353.488
#352	EOMES	6	9	15	968.536
#353	SP3	6	14	20	1747.667
#354	CREB3L1	6	15	21	1088.55
#355	PAX7	6	18	24	2324.031
#356	AEBP1	6	18	24	913.36
#357	ZNF91	6	12	18	3568.667
#358	NFIA	6	16	22	487.362
#359	TSHZ2	6	13	19	1581.98
#360	REL	6	18	24	428.951
#361	NFATC3	6	9	15	1184.009
#362	PROX1	6	13	19	1336.202
#363	PA2G4	6	19	25	455.185
#364	SMAD1	6	13	19	3015.344
#365	TRIM22	6	17	23	1573.877
#366	WT1	6	16	22	754.093
#367	ETS1	6	16	22	375.235
#368	MXD1	6	13	19	407.24
#369	HEYL	6	16	22	467.938
#370	ZNF167	6	17	23	1166.226
#371	ALS2CR8	6	15	21	1359.042
#372	IRF7	6	23	29	782.356
#373	PRRX1	6	13	19	621.158
#374	HLF	6	22	28	1335.694
#375	TWIST1	6	13	19	1828.429
#376	SOLH	6	14	20	646.173
#377	LCOR	6	18	24	2094.483
#378	RARB	6	18	24	456.065
#379	SMAD5	6	13	19	1404.645
#380	GTF2H2	6	15	21	377.926
#381	CDKN2A	6	23	29	1795.057
#382	PURB	6	19	25	1520.247
#383	PPARA	6	13	19	1115.94
#384	NR2F6	6	10	16	1072.85
#385	RCOR1	6	13	19	1143.773
#386	UBN1	6	14	20	1546.683
#387	LMO4	6	13	19	150.992
#388	JUN	5	13	18	475.008
#389	POU3F2	5	21	26	797.512
#390	ZSCAN18	5	24	29	1251.011
#391	TFDP2	5	10	15	1347.908
#392	POU6F1	5	19	24	872.626
#393	TP63	5	20	25	677.255
#394	RUNX1T1	5	13	18	814.91
#395	ZNF165	5	22	27	1020.109
#396	POU2F3	5	16	21	1707.407
#397	BHLHE40	5	13	18	169.395
#398	TBX4	5	11	16	2379.88
#399	SOX12	5	16	21	1220.842
#400	ELF5	5	18	23	575.855
#401	EGR1	5	12	17	1076.076
#402	SIX2	5	19	24	382.429
#403	ZFHX4	5	14	19	1949.16
#404	ISX	5	14	19	832.6
#405	TRIM28	5	19	24	555.534
#406	HIF3A	5	18	23	791.133
#407	HOXB13	5	13	18	1691.918
#408	HOXA1	5	17	22	1433.301
#409	SPEN	5	14	19	699.594
#410	KDM5A	5	15	20	785.737
#411	ZNF238	5	16	21	591.854
#412	TFEB	5	12	17	1098.943
#413	CEBPA	5	19	24	694.342
#414	GATAD2B	5	14	19	1550.774
#415	HEY1	5	13	18	105.667
#416	ZKSCAN1	5	18	23	2032.329
#417	TCFL5	5	18	23	1183.152
#418	ELF4	5	17	22	423.89
#419	ZNF85	5	15	20	790.097
#420	DDIT3	4	15	19	690.375
#421	MLL	4	14	18	666.559
#422	TBX21	4	13	17	185.98
#423	TFCP2L1	4	23	27	559.08
#424	TGIF1	4	10	14	1684.076
#425	SPIB	4	17	21	711.819
#426	FOXL1	4	14	18	517.78
#427	BATF	4	14	18	409.245
#428	NFE2	4	21	25	1359.504
#429	ELF1	4	8	12	218.389
#430	ZNF323	4	12	16	398.534
#431	RUNX2	4	22	26	874.599
#432	HOXC11	4	17	21	1361.446
#433	ETV6	4	9	13	56.863
#434	TAF4B	4	21	25	501.965
#435	NFX1	4	9	13	143.485
#436	ZFHX3	4	11	15	243.386
#437	STAT4	4	14	18	847.735
#438	JDP2	4	13	17	140.745
#439	PPARG	4	23	27	3607.684
#440	SREBF1	4	22	26	1776.705
#441	ZNF75D	3	11	14	186.812
#442	ZNF83	3	24	27	899.276
#443	ZFP36L1	3	17	20	986.291
#444	IRF2	3	19	22	719.262
#445	MTA1	3	19	22	408.255
#446	TEAD2	3	6	9	8.132
#447	MEF2C	3	18	21	801.989
#448	MEOX1	3	19	22	487.305
#449	C1orf85	3	19	22	132.672
#450	BCL11B	3	21	24	1923.742
#451	BNC1	3	8	11	137.488
#452	FBXW7	3	18	21	224.698
#453	MSX2	3	19	22	665.703
#454	HES1	3	24	27	770.741
#455	TRERF1	3	16	19	1013.838
#456	TEF	3	20	23	1045.805
#457	XBP1	3	12	15	237.952
#458	MEIS1	3	12	15	504.354
#459	JUNB	3	13	16	305.741
#460	RHOXF1	3	6	9	38.997
#461	ETV7	3	18	21	1241.955
#462	NR1D2	3	19	22	760.869
#463	ARNT2	2	22	24	2633.396
#464	ATF6	2	14	16	354.118
#465	DMRT2	2	15	17	150.262
#466	GATA5	2	13	15	51.177
#467	HOXA9	2	11	13	2110.523
#468	HOXD10	2	16	18	115.795
#469	FOXJ1	2	19	21	414.111
#470	TSC22D1	2	12	14	1668.67
#471	BTG2	2	12	14	13071.311
#472	MAF	2	13	15	81.873
#473	GATAD1	2	22	24	147.718
#474	NFYA	2	12	14	248.061
#475	KLF15	2	17	19	176.784
#476	BATF2	2	19	21	166.241
#477	ELF3	2	23	25	693.794
#478	IRF5	2	17	19	895.444
#479	ESRRG	2	32	34	549.437
#480	ASCL2	2	20	22	343.603
#481	IRX1	2	25	27	1671.379
#482	FOXA1	2	21	23	333.674
#483	MEIS3P1	2	19	21	560.672
#484	NPAS2	2	12	14	422.417
#485	PLAG1	2	21	23	121.42
#486	ARNTL	1	15	16	266.938
#487	HOXD4	1	23	24	82.553
#488	ZNF117	1	27	28	884.207
#489	IRF4	1	15	16	145.923
#490	ASCL1	1	10	11	28.684
#491	PLAGL2	1	20	21	69.481
#492	HOXD8	1	16	17	2712.697
#493	AHR	1	12	13	59.504
#494	YY1	1	10	11	795.304
#495	LHX9	0	18	18	0
#496	CTBP1	0	18	18	0
#497	ZIC1	0	11	11	0
#498	FOXC1	0	23	23	0
#499	MYCN	0	19	19	0
#500	SOX18	0	13	13	0