Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	BTAF1	97	0	97	0
#2	ZRANB2	74	3	77	3312.258
#3	AHCTF1	72	2	74	1759.823
#4	CTCF	71	3	74	27.071
#5	MEF2C	64	10	74	4519.731
#6	NR2C2	62	8	70	305.287
#7	ADNP	59	2	61	9.392
#8	CREBBP	58	5	63	79.933
#9	NCOR1	56	5	61	61.292
#10	BLZF1	55	2	57	28.75
#11	CREB1	52	5	57	321.157
#12	ZNF33A	51	5	56	290.95
#13	NPAT	51	9	60	440.198
#14	NOLC1	51	7	58	6868.428
#15	TAF5	48	5	53	51.988
#16	RBPJ	46	8	54	287.252
#17	ZNF189	45	10	55	277.368
#18	CSRNP1	45	10	55	675.191
#19	FBXW7	45	9	54	210.336
#20	PURB	43	9	52	194.564
#21	GCFC1	42	8	50	4571.944
#22	ZEB1	42	13	55	9262.22
#23	POU2F1	41	9	50	971.88
#24	ESRRA	41	8	49	408.89
#25	RELA	40	7	47	948.023
#26	CREBZF	40	10	50	707.684
#27	C5orf41	40	9	49	111.11
#28	MLL	39	12	51	168.691
#29	HOXA6	39	0	39	0
#30	USF2	39	6	45	1785.181
#31	HMG20A	38	14	52	1241.368
#32	RCOR1	38	11	49	563.088
#33	HINFP	38	13	51	2371.923
#34	STRN3	37	13	50	941.852
#35	CUX1	37	8	45	3077.241
#36	BRD8	37	11	48	209.074
#37	KLF6	37	11	48	264.597
#38	RFXANK	36	8	44	949.824
#39	TAF4	36	11	47	135.345
#40	ATF1	36	9	45	1607.294
#41	SUPT4H1	36	10	46	615.342
#42	ELK4	36	11	47	1183.408
#43	KDM5A	36	11	47	211.092
#44	IRF2	35	11	46	977.645
#45	E2F6	35	12	47	3734.996
#46	ZBTB38	34	7	41	2021.537
#47	ZNF24	34	16	50	1245.997
#48	ATF2	34	7	41	676.314
#49	NR1H2	33	12	45	1206.701
#50	IRF4	33	13	46	352.219
#51	E2F4	33	3	36	229.109
#52	LASS2	32	18	50	3298.077
#53	TAF10	32	4	36	130.969
#54	ZNF213	32	2	34	222.133
#55	RERE	32	12	44	863.69
#56	RUNX3	32	7	39	1662.781
#57	ECSIT	32	7	39	1643.881
#58	TBP	31	10	41	7800.292
#59	MTF1	31	12	43	1172.888
#60	ARID4A	31	15	46	21990.09
#61	ELK3	31	11	42	3702.815
#62	TRIM28	31	3	34	169.834
#63	TFE3	30	13	43	515.934
#64	NFXL1	30	14	44	1245.038
#65	MAFF	30	10	40	440.381
#66	UBN1	30	6	36	1055.902
#67	RELB	30	10	40	212.753
#68	HOXB4	30	7	37	574.209
#69	SCAND1	29	7	36	190.884
#70	BUD31	29	11	40	1225.152
#71	ZNF445	29	12	41	1552.066
#72	ADNP2	28	11	39	584.457
#73	ZNF37A	28	8	36	1108.493
#74	ZNF397	28	13	41	5319.082
#75	HMGA1	28	15	43	1357.041
#76	YBX1	27	6	33	778.961
#77	C2orf3	27	9	36	269.415
#78	PAX8	27	9	36	759.647
#79	DRAP1	27	9	36	460.777
#80	IRF3	27	9	36	690.866
#81	PTTG1	27	15	42	1511.935
#82	FOXO1	27	17	44	1511.579
#83	GABPA	27	15	42	825.198
#84	NFE2L2	26	14	40	2108.656
#85	SLC2A4RG	26	14	40	1172.398
#86	PRDM1	26	12	38	1565.791
#87	TSHZ1	26	8	34	14768.356
#88	REXO4	26	14	40	1250.884
#89	ZNF277	25	12	37	1259.09
#90	NFX1	25	11	36	175.605
#91	ZNF394	25	18	43	2003.613
#92	AATF	25	13	38	2363.893
#93	KLF9	25	14	39	732.594
#94	ZNF236	25	6	31	10035.829
#95	ZGPAT	24	10	34	875.589
#96	KLF3	24	13	37	561.355
#97	SIX5	24	9	33	851.423
#98	AFF1	24	9	33	2793.2
#99	HMG20B	24	12	36	1754.681
#100	SIN3A	24	15	39	3094.464
#101	PRDM2	24	4	28	303.446
#102	BACH1	24	11	35	570.662
#103	NFYB	24	12	36	1269.67
#104	STAT2	23	21	44	1754.844
#105	ELK1	23	12	35	1731.637
#106	CREM	23	14	37	744.476
#107	BCL3	23	14	37	774.427
#108	MESP1	23	11	34	579.977
#109	FLI1	23	8	31	208.372
#110	NFYC	23	12	35	1362.562
#111	SMAD4	23	10	33	575.403
#112	MAFB	23	4	27	754.656
#113	ZHX2	23	19	42	4159.153
#114	HMGB2	23	12	35	2063.583
#115	CIR1	22	14	36	3553.632
#116	ZKSCAN1	22	14	36	751.934
#117	TAF12	22	9	31	2664.912
#118	TFAP2C	22	12	34	1754.118
#119	HOXC4	22	17	39	1128.22
#120	ARNT	22	16	38	1293.312
#121	TFEB	22	21	43	3329.645
#122	PKNOX1	22	14	36	2283.432
#123	TRIM25	22	17	39	1182.914
#124	LCOR	22	11	33	1087.903
#125	CBFA2T3	22	21	43	1299.556
#126	NFATC2	22	17	39	3273.626
#127	ATF4	22	16	38	2967.243
#128	ZNF217	21	15	36	1413.218
#129	GABPB1	21	14	35	3053.85
#130	ZNF281	21	14	35	2773.749
#131	CNOT8	21	12	33	718.811
#132	AHR	21	18	39	3036.994
#133	SPEN	21	12	33	1013.414
#134	CREB3	21	14	35	24871.11
#135	CTNNB1	21	13	34	975.459
#136	FOSB	21	11	32	1261.765
#137	ZBTB25	21	15	36	414.82
#138	E2F2	21	20	41	3783.63
#139	TULP4	21	7	28	403.627
#140	RARA	21	9	30	2552.149
#141	PHF1	20	12	32	1208.137
#142	ISL2	20	14	34	2673.187
#143	SMAD5	20	13	33	2641.22
#144	PBX1	20	15	35	4981.438
#145	ZNF148	20	9	29	323.063
#146	SP3	20	11	31	1717.548
#147	MTA1	20	16	36	1806.953
#148	PCGF6	20	15	35	1169.006
#149	KLF16	20	5	25	83.865
#150	ZNF193	20	12	32	1185.598
#151	ZHX1	20	16	36	673.935
#152	SNAPC5	20	21	41	1906.097
#153	RFX1	20	11	31	642.383
#154	FOXN2	20	18	38	763.137
#155	NOTCH1	20	23	43	1962.637
#156	HNRNPAB	20	17	37	751.78
#157	SRF	20	13	33	1305.617
#158	RBCK1	19	13	32	202.41
#159	LASS5	19	15	34	251.345
#160	UBP1	19	18	37	841.476
#161	CTBP1	19	17	36	6055.955
#162	NFATC1	19	16	35	2143.669
#163	BHLHE40	19	14	33	1059.829
#164	NR3C2	19	25	44	2291.322
#165	MITF	19	16	35	1129.733
#166	ZNF45	19	15	34	313.799
#167	SUPT6H	19	13	32	1588.951
#168	TAF4B	19	13	32	1030.954
#169	MSRB2	19	16	35	4148.152
#170	KLF11	19	17	36	1558.906
#171	REST	19	7	26	366.022
#172	JUN	19	8	27	699.901
#173	GATAD2A	18	21	39	2748.79
#174	ZFP36L2	18	16	34	1355.545
#175	ZNF175	18	17	35	625.671
#176	ZNF639	18	14	32	1022.7
#177	ZFP90	18	14	32	797.958
#178	TCF3	18	15	33	2839.494
#179	CREB3L2	18	16	34	916.711
#180	SNAPC2	18	15	33	2512.084
#181	ZNF117	18	14	32	661.771
#182	ZNF70	18	20	38	577.246
#183	ZFPM1	18	14	32	2100.748
#184	TCF19	17	13	30	1639.027
#185	CEBPA	17	21	38	4162.417
#186	NFE2L1	17	14	31	1232.729
#187	DMTF1	17	11	28	1951.568
#188	HNF4G	17	16	33	4375.663
#189	SALL2	17	16	33	1202.526
#190	IRF1	17	18	35	1327.316
#191	GTF2H2	17	14	31	947.686
#192	KLF15	17	12	29	1278.518
#193	PURA	17	14	31	328.557
#194	TAF5L	17	16	33	1045.098
#195	ELF1	17	11	28	480.429
#196	NR4A2	17	12	29	380.483
#197	ZNF215	17	22	39	1961.242
#198	ZNF92	17	21	38	711.717
#199	TRERF1	17	14	31	500.903
#200	TFDP2	17	14	31	508.822
#201	BHLHE41	17	17	34	560.014
#202	HEY2	17	19	36	1908.322
#203	UHRF1	17	14	31	740.132
#204	CREBL2	16	12	28	852.182
#205	ZNF75D	16	15	31	309.24
#206	FOXM1	16	8	24	1147.663
#207	MAF	16	12	28	998.312
#208	TCF20	16	26	42	1655.656
#209	TCF7L2	16	11	27	877.503
#210	EBF1	16	16	32	19122.421
#211	NR2C1	16	18	34	697.676
#212	DDIT3	16	23	39	1177.318
#213	PPARA	16	14	30	177.587
#214	KLF10	16	12	28	169.123
#215	EDF1	16	10	26	1059.56
#216	E2F8	16	19	35	1329.504
#217	PHF5A	16	14	30	773.469
#218	IRF8	16	5	21	190.694
#219	JUND	16	15	31	663.826
#220	NFAT5	15	13	28	1429.781
#221	TSC22D2	15	17	32	773.15
#222	ZNF83	15	16	31	428.778
#223	NFKB1	15	15	30	4056.443
#224	PLAGL2	15	17	32	819.015
#225	ZNF134	15	15	30	616.989
#226	MLX	15	15	30	601.911
#227	HOXB7	15	20	35	3348.456
#228	CEBPD	15	7	22	500.447
#229	TSC22D3	15	11	26	1160.531
#230	ZNF628	15	18	33	754.338
#231	MYCN	14	9	23	7531.001
#232	RB1	14	28	42	2153.61
#233	CREB3L4	14	11	25	785.428
#234	YEATS4	14	19	33	2146.74
#235	TAL1	14	13	27	1401.982
#236	TRPS1	14	11	25	773.15
#237	PPARD	14	12	26	2495.82
#238	ZNF202	14	11	25	220.161
#239	ZFP36L1	14	18	32	1040.343
#240	HDAC2	14	20	34	735.201
#241	MXD1	14	28	42	1841.737
#242	GAS7	14	16	30	2587.154
#243	FUBP1	14	16	30	701.608
#244	HOXA2	14	17	31	2285.579
#245	ZSCAN29	14	19	33	1522.086
#246	FOXJ2	14	19	33	500.511
#247	PCGF2	14	21	35	1639.125
#248	TARDBP	14	20	34	1332.891
#249	SP140	13	14	27	250.032
#250	HSF2	13	19	32	794.115
#251	BACH2	13	17	30	877.518
#252	ZEB2	13	10	23	3010.728
#253	EGR1	13	18	31	575.936
#254	EOMES	13	13	26	1684.678
#255	BATF3	13	17	30	704.344
#256	CBFB	13	18	31	1182.027
#257	SMAD2	13	17	30	1021.209
#258	MNT	13	17	30	615.002
#259	FOXO3	13	15	28	2914.85
#260	IRF7	13	13	26	814.025
#261	MAX	13	13	26	2200.73
#262	FOXK1	13	24	37	2601.446
#263	ZKSCAN5	13	12	25	198.928
#264	RUNX1	13	20	33	2819.889
#265	FOXN3	12	9	21	76.877
#266	BTG2	12	32	44	2715.717
#267	SMAD3	12	27	39	1308.873
#268	MYBL2	12	18	30	913.493
#269	TCF25	12	11	23	290.57
#270	E2F3	12	14	26	1054.833
#271	ELF2	12	17	29	1363.7
#272	BCL6	12	18	30	691.343
#273	ATF3	12	17	29	339.275
#274	CCRN4L	12	19	31	2033.019
#275	TP63	12	13	25	1846.383
#276	CEBPB	12	19	31	978.37
#277	TCEAL1	12	18	30	316.451
#278	TWIST1	12	18	30	1575.399
#279	ETS1	12	23	35	2718.9
#280	PBX2	12	18	30	804.19
#281	HIF3A	12	13	25	4408.721
#282	KLF4	12	19	31	722.886
#283	TFDP1	12	19	31	1205.445
#284	HOXA7	12	10	22	905.428
#285	STAT3	11	19	30	6383.829
#286	ENO1	11	13	24	1761.461
#287	CBL	11	12	23	592.925
#288	ZNF238	11	27	38	803.564
#289	EHF	11	16	27	937.545
#290	PHTF1	11	29	40	1771.424
#291	ZNF138	11	12	23	962.242
#292	MZF1	11	22	33	625.072
#293	ARNTL2	11	16	27	3169.785
#294	SP4	11	14	25	375.239
#295	CNOT7	11	14	25	1485.395
#296	ZNF207	11	20	31	1579.252
#297	ZSCAN21	11	18	29	715.313
#298	MKX	11	27	38	1638.179
#299	ELF4	11	24	35	570.213
#300	KDM5B	11	20	31	738.349
#301	ZNF323	11	19	30	1899.684
#302	PA2G4	11	13	24	2305.127
#303	GTF2H3	11	16	27	601.078
#304	ESRRG	11	25	36	594.838
#305	POU2F2	11	15	26	6631.21
#306	RFX5	10	24	34	634.645
#307	STAT5B	10	24	34	4451.803
#308	SNAI3	10	25	35	4786.321
#309	ZXDC	10	10	20	738.546
#310	NR1D2	10	13	23	527.963
#311	ZSCAN16	10	22	32	675.983
#312	ZNF81	10	21	31	1382.877
#313	NFIA	10	28	38	1056.763
#314	ZNF274	10	21	31	1032.452
#315	FOSL2	10	16	26	2405.321
#316	TEF	10	15	25	1943.318
#317	HOXA10	10	10	20	376.198
#318	MEF2A	10	15	25	1140.678
#319	ZNF71	10	21	31	259.408
#320	MEF2D	10	27	37	1455.275
#321	SIX1	10	18	28	727.754
#322	MYNN	10	13	23	148.606
#323	TAF7	10	23	33	851.099
#324	MBD1	10	11	21	79.219
#325	TGIF1	10	30	40	2514.415
#326	HOXA5	10	12	22	658.124
#327	RCAN1	10	27	37	709.687
#328	CLOCK	10	16	26	722.376
#329	PLSCR1	10	19	29	3882.567
#330	MGA	10	9	19	359.361
#331	HIF1A	10	14	24	382.627
#332	SP1	10	18	28	163.861
#333	ZNF498	10	14	24	259.891
#334	KLF12	9	21	30	931.711
#335	TP53	9	22	31	768.602
#336	HMGB1	9	9	18	293.027
#337	NR2F2	9	12	21	614.161
#338	FOXP2	9	13	22	63.224
#339	HCLS1	9	23	32	993.633
#340	YY1	9	23	32	1255.601
#341	MYC	9	23	32	2751.802
#342	RORB	9	15	24	881.519
#343	TBX21	9	14	23	548.225
#344	IRF9	9	17	26	248.728
#345	NFATC3	9	26	35	520.291
#346	TCF4	9	28	37	2203.603
#347	FOXC1	9	12	21	868.383
#348	L3MBTL4	9	20	29	747.989
#349	ESR1	9	26	35	779.737
#350	SATB1	9	29	38	925.414
#351	STAT6	9	25	34	1627.359
#352	ETV6	9	27	36	1744.882
#353	HOXA3	9	15	24	1363.351
#354	CSDA	9	29	38	2322.373
#355	LHX8	9	16	25	949.616
#356	ZNF434	9	20	29	953.874
#357	TSHZ2	9	22	31	695.501
#358	EGR3	9	23	32	4811.789
#359	FOXK2	9	20	29	1255.745
#360	OVOL1	9	20	29	1871.486
#361	ZNF268	9	20	29	225.182
#362	GLIS3	9	23	32	1790.447
#363	TFCP2	9	19	28	484.86
#364	KLF7	8	20	28	334.208
#365	CNBP	8	14	22	471.661
#366	HDX	8	18	26	3714.155
#367	ZSCAN18	8	23	31	545.793
#368	ZNF256	8	26	34	916.797
#369	TADA3	8	15	23	230.584
#370	ZNF140	8	15	23	670.92
#371	LEF1	8	30	38	971.941
#372	ATF7	8	20	28	1356.987
#373	ETV5	8	35	43	1116.96
#374	SREBF2	8	25	33	596.953
#375	ZNF3	8	21	29	1201.535
#376	TFAM	8	11	19	1160.038
#377	FOXP1	8	24	32	561.015
#378	AFF4	8	17	25	429.189
#379	RXRA	8	20	28	590.472
#380	TFEC	8	23	31	1090.737
#381	E2F5	8	24	32	1743.193
#382	LASS6	8	36	44	1375.819
#383	NR2F6	7	21	28	470.903
#384	ATF6	7	24	31	624.851
#385	GATAD1	7	14	21	334.701
#386	RAX	7	5	12	79.89
#387	KLF1	7	7	14	1244.28
#388	TAF1B	7	26	33	771.363
#389	TRIM22	7	27	34	1513.061
#390	ZNF496	7	16	23	178.58
#391	MTA3	7	20	27	427.304
#392	HDAC1	7	28	35	499.669
#393	ZNF367	7	20	27	401.086
#394	NR2F1	7	12	19	349.735
#395	ATF5	7	23	30	900.875
#396	MEIS2	7	27	34	1505.788
#397	VAV1	7	27	34	736.059
#398	NR4A3	7	18	25	10059.528
#399	SNAI2	7	17	24	1033.833
#400	SLC30A9	7	16	23	395.889
#401	NR4A1	7	16	23	683.821
#402	STAT1	7	21	28	512.116
#403	ZNF449	7	15	22	359.473
#404	HOXD1	7	16	23	326.947
#405	ZXDA	7	19	26	343.774
#406	ZC3H8	7	21	28	300.738
#407	NR1H3	7	21	28	386.562
#408	NFYA	7	22	29	1267.173
#409	AEBP1	7	21	28	1092.031
#410	SCAND3	7	24	31	873.275
#411	NR3C1	7	25	32	495.296
#412	PLAG1	7	18	25	595.09
#413	SREBF1	7	20	27	888.11
#414	NFE2	7	7	14	294.348
#415	RFXAP	6	20	26	2294.208
#416	FOS	6	27	33	341.785
#417	HOXA9	6	11	17	583.925
#418	SOX7	6	22	28	1083.252
#419	CBFA2T2	6	26	32	503.007
#420	HOXA1	6	26	32	3674.601
#421	MSL3	6	34	40	796.613
#422	MYCL1	6	24	30	544.277
#423	HOXB2	6	19	25	839.922
#424	IKZF1	6	9	15	69.974
#425	ARX	6	28	34	2317.41
#426	SOX6	6	27	33	198.98
#427	ZNF232	6	25	31	304.908
#428	POU6F1	6	17	23	471.74
#429	ETV7	6	19	25	690.286
#430	SCMH1	6	17	23	541.954
#431	STAT5A	6	27	33	1948.212
#432	JUNB	6	23	29	881.826
#433	SIX4	6	26	32	464.325
#434	IRF6	6	16	22	957.372
#435	TCF12	6	17	23	236.66
#436	VDR	5	34	39	876.498
#437	MLLT10	5	17	22	99.648
#438	C1orf85	5	18	23	537.615
#439	DBP	5	16	21	482.288
#440	NFIB	5	25	30	1046.384
#441	ZNF33B	5	19	24	247.586
#442	EPAS1	5	32	37	1518.11
#443	SATB2	5	27	32	1115.472
#444	EGR2	5	19	24	456.731
#445	NANOGNB	5	23	28	394.293
#446	SPIC	5	13	18	525.125
#447	RUNX1T1	5	22	27	3082.627
#448	MAFK	5	23	28	1874.489
#449	SOX30	5	15	20	469.147
#450	NKX3-2	5	21	26	1050.098
#451	LMO4	5	27	32	1673.451
#452	ZSCAN2	5	27	32	551.428
#453	TGIF2	5	22	27	3416.038
#454	TSC22D1	5	28	33	607.602
#455	ZFPM2	5	18	23	546.818
#456	ZNF167	5	22	27	778.878
#457	TCFL5	5	23	28	253.913
#458	ZNF85	5	28	33	698.241
#459	ELF3	5	12	17	651.362
#460	ZBTB17	5	21	26	1327.303
#461	HMBOX1	5	22	27	224.448
#462	SOX2	5	14	19	452.678
#463	E2F7	4	20	24	173.58
#464	DMRT2	4	30	34	1392.627
#465	GATA3	4	28	32	1324.544
#466	ZNF174	4	22	26	700.123
#467	CDKN2A	4	22	26	280.136
#468	CITED2	4	22	26	666.262
#469	TAF6	4	16	20	61.294
#470	NFIC	4	24	28	289.252
#471	HIRA	4	28	32	298.108
#472	STAT4	4	34	38	1259.049
#473	ARNT2	4	32	36	442.399
#474	ZNF643	4	34	38	1035.173
#475	HES1	4	27	31	518.849
#476	NFE2L3	3	28	31	658.02
#477	SOX4	3	33	36	1903.838
#478	PEG3	3	19	22	1350.149
#479	ZNF165	3	20	23	2577.033
#480	ZNF131	3	19	22	585.728
#481	ESR2	3	25	28	788.965
#482	KLF2	3	17	20	235.333
#483	RORA	3	24	27	85.593
#484	GLI3	3	24	27	407.468
#485	ZNF133	3	22	25	385.259
#486	ZNF91	3	23	26	243.261
#487	MYF6	3	26	29	946.402
#488	WNT5A	2	39	41	792.951
#489	TEAD1	2	27	29	118.857
#490	HEY1	2	32	34	302.154
#491	KLF5	2	26	28	100.596
#492	POU4F1	2	26	28	184.678
#493	RUNX2	2	28	30	1083.256
#494	ETV1	1	33	34	134.066
#495	CREB5	1	28	29	99.331
#496	PBX3	1	33	34	272.578
#497	SMAD1	1	31	32	118.677
#498	NFIL3	1	34	35	64.771
#499	IRF5	0	24	24	0
#500	HOPX	0	27	27	0