Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	FOXA1	59	0	59	0
#2	ESR1	46	4	50	182.693
#3	XBP1	45	4	49	2679.781
#4	YBX1	42	4	46	320.642
#5	GTF2I	41	3	44	92.115
#6	FOXM1	40	3	43	391.018
#7	GATA3	38	3	41	161.924
#8	TAF4B	37	7	44	502.04
#9	POU3F1	35	6	41	1158.332
#10	SPDEF	35	4	39	1505.515
#11	SOX10	34	4	38	122.573
#12	AR	34	4	38	2058.734
#13	FOXC1	34	3	37	67.309
#14	ENO1	34	5	39	807.294
#15	ZNF155	33	3	36	560.174
#16	PTTG1	33	7	40	794.495
#17	TCF3	32	5	37	374.88
#18	SOX4	32	7	39	1851.949
#19	ZNF367	32	4	36	2291.676
#20	GAS7	31	8	39	395.721
#21	E2F3	31	7	38	827.208
#22	BTG2	31	4	35	431.039
#23	HSF1	31	6	37	952.723
#24	L3MBTL4	30	9	39	3322.844
#25	ELF5	29	6	35	97.189
#26	FOSB	29	2	31	251.03
#27	ERG	28	7	35	2519.235
#28	EN1	28	9	37	221.024
#29	PHF1	28	9	37	1797.334
#30	RXRB	28	5	33	852.951
#31	SP1	27	5	32	924.917
#32	GATA6	27	11	38	3087.872
#33	HIC1	27	6	33	276.327
#34	CBFB	25	3	28	225.98
#35	FOS	25	6	31	532.578
#36	NFATC2	25	6	31	1202.838
#37	HMGA1	24	6	30	361.272
#38	AEBP1	24	13	37	2128.708
#39	KLF5	24	7	31	137.194
#40	IRX1	24	13	37	3441.944
#41	E2F7	24	3	27	216.305
#42	GCFC1	24	10	34	1972.345
#43	ZBTB48	23	10	33	3061.485
#44	SOX8	23	9	32	2403.854
#45	ETV6	23	10	33	1483.84
#46	ZHX2	23	8	31	750.69
#47	EBF1	22	9	31	1625.511
#48	MSX2	22	10	32	1274.555
#49	SOX6	22	10	32	1074.483
#50	IRF8	22	2	24	39.882
#51	MYOG	22	17	39	2374.437
#52	EGR1	22	7	29	1490.56
#53	FOXO1	22	5	27	641.488
#54	RCAN1	21	10	31	1576.855
#55	ZNF92	21	14	35	3295.193
#56	NFIX	21	11	32	1004.556
#57	GLI3	21	9	30	4838.619
#58	TCF19	20	11	31	3362.918
#59	MYCN	20	13	33	1871.942
#60	ETS1	20	10	30	2823.128
#61	ARNTL2	20	11	31	2989.589
#62	ATF3	20	6	26	428.735
#63	SIX5	20	13	33	1839.986
#64	SPIB	20	10	30	1636.907
#65	GBX1	20	15	35	3613.204
#66	BHLHE40	20	7	27	254.638
#67	EOMES	20	2	22	1066.664
#68	SOX13	20	6	26	3678.154
#69	KLF3	20	6	26	2204.038
#70	SOX21	20	15	35	3189.543
#71	FOXP3	19	11	30	1575.669
#72	NFE2L3	19	11	30	366.308
#73	LASS6	19	11	30	1635.364
#74	TCF7L2	19	11	30	1184.16
#75	TSC22D3	19	11	30	1907.982
#76	PRDM1	19	10	29	564.826
#77	NR2F1	19	18	37	1247.031
#78	TCF7L1	19	10	29	297.403
#79	AFF4	19	7	26	608.144
#80	MBD1	19	9	28	3032.226
#81	CSRNP1	19	4	23	92.017
#82	TSHZ2	18	6	24	205.333
#83	SALL1	18	15	33	3078.232
#84	SOX12	18	9	27	2313.783
#85	TFAP2A	18	7	25	519.639
#86	RUNX3	18	10	28	2164.007
#87	ZNF277	18	5	23	270.591
#88	TFDP1	18	9	27	2430.104
#89	ALX1	18	14	32	1179.668
#90	NR2E3	18	5	23	1306.699
#91	ZNF71	18	11	29	1619.398
#92	UHRF1	18	2	20	33.754
#93	ZNF193	18	12	30	3114.603
#94	ETV7	18	12	30	2529.701
#95	FOXC2	18	14	32	1500.62
#96	HOXB4	18	6	24	2029.862
#97	PGR	17	6	23	91.717
#98	HMG20B	17	12	29	2461.957
#99	NFIL3	17	13	30	2079.334
#100	TBX3	17	11	28	312.904
#101	ETV1	17	9	26	1413.438
#102	NR6A1	17	11	28	1835.792
#103	DLX6	17	12	29	1250.24
#104	GABPA	17	10	27	1902.722
#105	STAT1	17	12	29	1818.568
#106	TFDP2	16	12	28	924.519
#107	SOX11	16	8	24	636.369
#108	SNAI2	16	13	29	1412.096
#109	ZSCAN20	16	15	31	3045.087
#110	TCEAL1	16	9	25	346.046
#111	VENTX	16	11	27	417.502
#112	ZNF446	16	7	23	5091.267
#113	DMBX1	16	10	26	1616.776
#114	ZNF91	16	17	33	1147.527
#115	ZNF19	16	9	25	998.927
#116	BACH2	16	14	30	3915.561
#117	WT1	16	13	29	1937.081
#118	SOX9	16	14	30	784.103
#119	MEF2A	16	14	30	1865.938
#120	E2F8	16	7	23	255.601
#121	RFX3	16	13	29	1485.934
#122	HES6	16	11	27	557.473
#123	IRF1	16	7	23	488.183
#124	GATAD2B	16	11	27	724.686
#125	OTX2	16	13	29	2093.412
#126	MEOX2	16	11	27	317.412
#127	ZFP42	15	6	21	253.704
#128	TULP4	15	11	26	3884.452
#129	AHCTF1	15	6	21	340.435
#130	PLAG1	15	13	28	1413.762
#131	ATF5	15	13	28	1521.858
#132	SIX3	15	13	28	766.401
#133	NR5A1	15	7	22	1304.262
#134	NFIB	15	10	25	746.316
#135	CDKN2A	15	10	25	3030.375
#136	SP3	15	8	23	563.306
#137	BATF2	15	9	24	1091.92
#138	TEAD4	15	8	23	2522.931
#139	JUN	15	8	23	1375.49
#140	TFCP2L1	15	10	25	250.658
#141	CREBBP	14	7	21	341.585
#142	BHLHE41	14	11	25	854.726
#143	NFIA	14	13	27	1239.924
#144	ZEB1	14	17	31	1721.638
#145	LEF1	14	12	26	2899.807
#146	ANKRD30A	14	10	24	498.152
#147	HOXD1	14	14	28	1674.32
#148	ZIC5	14	12	26	2195.622
#149	CITED1	14	12	26	706.28
#150	TRIM22	14	6	20	841.571
#151	SMAD5	14	13	27	7358.678
#152	HHEX	14	13	27	1351.827
#153	PRRX1	14	5	19	553.251
#154	SUPT6H	14	6	20	824.432
#155	TWIST1	14	12	26	2038.81
#156	HOXD9	14	12	26	1472.543
#157	HNF4G	14	16	30	1562.281
#158	SALL2	14	9	23	817.745
#159	SREBF1	14	11	25	1847.235
#160	PPARA	14	9	23	1450.46
#161	SCAND1	14	15	29	2638.969
#162	PHTF1	14	3	17	199.796
#163	BCL11B	14	5	19	418.698
#164	ZXDC	14	11	25	3427.226
#165	NFKB2	14	13	27	4511.234
#166	ZNF90	14	12	26	1571.089
#167	PBX1	14	13	27	6386.91
#168	PITX2	14	15	29	3369.35
#169	ZNF157	14	15	29	2870.334
#170	SMAD3	13	10	23	952.955
#171	POU4F1	13	11	24	848.706
#172	NKX2-3	13	14	27	2353.622
#173	FUBP1	13	14	27	1548
#174	NFIC	13	13	26	806.926
#175	ALS2CR8	13	15	28	5882.695
#176	FOXK1	13	14	27	1763.162
#177	THRB	13	15	28	1377.364
#178	CREB3L4	13	6	19	576.855
#179	ZNF397	13	21	34	3662.746
#180	HOXB7	13	12	25	920.677
#181	CREB3L1	13	8	21	239.845
#182	ZFP36L1	13	12	25	2437.434
#183	HOXD13	13	15	28	1103.601
#184	LMX1B	13	12	25	946.033
#185	LHX6	13	13	26	1443.772
#186	DLX2	13	11	24	1052.378
#187	MYBL2	13	12	25	416.819
#188	FOXP4	13	8	21	875.778
#189	CSDA	13	9	22	339.732
#190	ZNF154	13	10	23	1405.477
#191	NFATC4	13	7	20	1128.615
#192	HLF	13	15	28	1140.615
#193	ZFPM2	13	9	22	472.822
#194	MYT1	13	12	25	1296.294
#195	BCL6	13	8	21	501.707
#196	TFEC	13	11	24	1724.708
#197	MAF	13	10	23	1068.041
#198	SIM1	13	13	26	2208.199
#199	EGR2	13	9	22	678.816
#200	SATB1	12	14	26	896.922
#201	NR4A1	12	8	20	282.208
#202	ONECUT2	12	8	20	358.949
#203	MLX	12	17	29	1223.262
#204	POU1F1	12	11	23	583.629
#205	MECOM	12	13	25	1154.621
#206	SIX4	12	15	27	2531.566
#207	MYNN	12	15	27	1553.431
#208	CEBPD	12	17	29	1395.619
#209	HOXC9	12	8	20	286.34
#210	POU2F2	12	11	23	1091.07
#211	TCF7	12	8	20	754.34
#212	SP140	12	10	22	2099.75
#213	MTA3	12	9	21	188.883
#214	CNOT7	12	15	27	1016.555
#215	SIN3A	12	17	29	1120.82
#216	TCFL5	12	15	27	1155.165
#217	ZNF236	12	17	29	939.653
#218	NPAT	12	10	22	1096.46
#219	KLF4	12	10	22	267.438
#220	MIXL1	12	14	26	1646.982
#221	SOX30	12	10	22	890.867
#222	KDM5A	12	15	27	1061.685
#223	LMO4	11	14	25	270.055
#224	EGR3	11	9	20	193.876
#225	KLF6	11	11	22	1198.326
#226	HOXB13	11	16	27	1022.651
#227	TRIM29	11	18	29	3368.006
#228	GTF2H2	11	9	20	1093.261
#229	NR4A3	11	11	22	341.851
#230	NKX2-1	11	10	21	1239.57
#231	IRX5	11	6	17	139.439
#232	TAF4	11	11	22	706.732
#233	HOXC13	11	11	22	455.804
#234	ZNF85	11	11	22	1231.674
#235	MYCL1	11	10	21	1004.247
#236	TEAD2	11	12	23	924.045
#237	LHX1	11	8	19	211.92
#238	PRDM2	11	10	21	872.426
#239	TBX4	11	14	25	862.148
#240	MYT1L	11	16	27	1620.911
#241	MGA	11	9	20	583.157
#242	ZNF93	11	11	22	653.306
#243	FOXR1	11	18	29	1013.604
#244	EVX1	11	10	21	876.39
#245	KLF16	11	19	30	2085.089
#246	PHOX2A	11	16	27	898.361
#247	DLX4	11	19	30	1587.576
#248	HOXA13	11	13	24	2395.015
#249	SPI1	11	9	20	734.902
#250	HIRA	11	12	23	434.187
#251	HOXD11	11	22	33	1571.506
#252	RFXAP	11	15	26	6309.395
#253	MXD1	11	17	28	3094.838
#254	ARX	11	16	27	1082.309
#255	RORC	11	15	26	542.039
#256	RERE	11	9	20	1548.841
#257	ZSCAN18	11	12	23	580.151
#258	CSRNP3	10	13	23	1697.882
#259	PPBPL2	10	16	26	1470.754
#260	BLZF1	10	14	24	854.235
#261	NANOGNB	10	13	23	971.768
#262	SPIC	10	10	20	1469.908
#263	HOXA10	10	11	21	830.371
#264	ELK1	10	14	24	1275.236
#265	IRF6	10	16	26	2630.712
#266	HOXB3	10	10	20	452.229
#267	PPARG	10	12	22	1112.848
#268	GATA4	10	17	27	1449
#269	NEUROD1	10	7	17	1499.767
#270	HR	10	14	24	751.453
#271	ARNT2	10	20	30	1058.428
#272	ELK4	10	13	23	1385.495
#273	RELA	10	15	25	1536.049
#274	PLSCR1	10	14	24	1419.088
#275	ZNF167	10	10	20	971.423
#276	DMRT1	10	16	26	1170.181
#277	STAT5B	10	15	25	1185.106
#278	ZNF215	10	13	23	2300.64
#279	SLC26A3	10	16	26	729.998
#280	PCGF2	10	16	26	2636.294
#281	SIX2	10	19	29	906.591
#282	CUX2	10	12	22	1455.377
#283	CREB3L3	10	14	24	900.37
#284	TCF15	10	15	25	1530.033
#285	FOXB1	10	9	19	689.126
#286	ZNF135	10	13	23	1688.854
#287	POU2F3	10	11	21	1167.028
#288	HOXA5	10	10	20	354.059
#289	RFX1	10	14	24	1380.233
#290	C11orf9	10	17	27	1075.812
#291	ZBTB38	10	12	22	3838.863
#292	GBX2	10	18	28	1513.41
#293	POU6F1	10	13	23	1800.514
#294	CITED2	10	15	25	3196.155
#295	HOXA9	10	7	17	1903.607
#296	ETV4	10	16	26	4309.064
#297	MEOX1	10	17	27	1016.856
#298	ESR2	10	13	23	975.115
#299	NFATC1	10	17	27	993.968
#300	HOXA7	10	10	20	612.125
#301	ZNF207	10	5	15	320.006
#302	TFAP2B	10	17	27	1644.647
#303	BUD31	10	12	22	1011.428
#304	MSL3	9	18	27	1062.033
#305	FOXG1	9	15	24	1303.089
#306	PITX3	9	17	26	940.208
#307	HOXB8	9	17	26	2267.322
#308	CTBP1	9	9	18	659.677
#309	ZNF81	9	11	20	877.565
#310	ZSCAN5A	9	19	28	1850.264
#311	ZHX3	9	18	27	1493.213
#312	LHX2	9	13	22	823.552
#313	NFE2	9	12	21	738.482
#314	IRX2	9	22	31	3453.201
#315	ZIC3	9	10	19	1034.164
#316	PAX6	9	18	27	389.504
#317	SCML1	9	19	28	1912.894
#318	ZFHX4	9	17	26	2021.338
#319	PBX3	9	14	23	658.496
#320	SIM2	9	14	23	1318.557
#321	FOXI1	9	15	24	860.95
#322	HOXB9	9	12	21	2194.442
#323	SCAND2	9	6	15	246.991
#324	SOX2	9	21	30	1377.982
#325	SCAND3	9	13	22	827.343
#326	HOXC8	9	9	18	542.558
#327	TFAP2D	9	14	23	2063.765
#328	LHX4	9	11	20	1198.754
#329	ZNF165	9	14	23	587.733
#330	GSC	9	17	26	695.41
#331	GATA2	9	13	22	509.73
#332	TP53	9	13	22	917.635
#333	FOXD3	9	15	24	438.595
#334	ESRRB	9	14	23	907.519
#335	MESP1	9	12	21	3131.869
#336	ZEB2	9	14	23	1005.634
#337	GLI2	9	15	24	2334.841
#338	HEY1	9	15	24	1189.145
#339	NPAS2	9	15	24	1371.2
#340	ALX4	9	17	26	1226.47
#341	NR5A2	9	7	16	491.101
#342	KLF15	8	14	22	968.733
#343	ZIC2	8	16	24	794.253
#344	TLX1	8	19	27	580.744
#345	TBX22	8	15	23	1497.237
#346	TFAP2C	8	15	23	993.442
#347	TRPS1	8	19	27	1644.746
#348	GSC2	8	18	26	2170.021
#349	TAF13	8	17	25	1360.373
#350	IRF4	8	16	24	977.177
#351	ZNF396	8	16	24	1623.839
#352	EPAS1	8	15	23	826.288
#353	ZNF3	8	10	18	739.404
#354	MMP14	8	15	23	495.306
#355	SHOX	8	14	22	997.52
#356	WNT5A	8	17	25	991.44
#357	NCOR1	8	14	22	1082.699
#358	ZSCAN4	8	20	28	1089.988
#359	IRX4	8	14	22	1462.792
#360	ZNF238	8	17	25	696.922
#361	HMX1	8	20	28	1257.039
#362	BCL3	8	9	17	761.878
#363	MLLT10	8	18	26	1023.328
#364	PTH	8	9	17	893.349
#365	E2F5	8	16	24	1340.845
#366	NKX3-2	8	11	19	790.165
#367	ASCL2	8	22	30	1385.866
#368	NR1I2	8	17	25	1659.094
#369	ZNF117	8	14	22	928.093
#370	ESRRG	8	16	24	699.226
#371	DLX1	8	13	21	2712.376
#372	ST18	8	16	24	1346.181
#373	CREM	8	13	21	1203.469
#374	ZNF449	7	14	21	767.79
#375	SMAD6	7	16	23	778.604
#376	HIF3A	7	18	25	1512.52
#377	NR2F2	7	24	31	866.716
#378	HEY2	7	19	26	383.024
#379	DMRT2	7	22	29	2474.762
#380	BNC1	7	9	16	826.304
#381	EGR4	7	13	20	623.706
#382	ZFP36L2	7	8	15	411.921
#383	OLIG2	7	20	27	1015.756
#384	ZNF287	7	10	17	812.332
#385	NR0B1	7	8	15	405.551
#386	ZSCAN23	7	17	24	606.664
#387	GSX1	7	18	25	1944.921
#388	ZNF131	7	5	12	282.501
#389	LHX8	7	17	24	1186.165
#390	RARG	7	13	20	492.93
#391	SOX1	7	13	20	644.69
#392	HOXB2	7	10	17	444.088
#393	FOXN1	7	13	20	965.543
#394	NR1H4	7	16	23	2214.456
#395	ATF6B	7	15	22	656.304
#396	FOXO6	7	13	20	2577.085
#397	HOXB6	7	10	17	756.229
#398	SIX1	7	12	19	1454.069
#399	ELF3	7	13	20	521.551
#400	MITF	7	11	18	535.558
#401	ZIC1	7	11	18	90.154
#402	ZNF80	7	13	20	1670.807
#403	ZKSCAN3	7	12	19	1309.479
#404	C2orf3	7	17	24	1166.84
#405	NR3C2	7	19	26	983.743
#406	FEV	6	14	20	1680.94
#407	PKNOX1	6	10	16	317.328
#408	RUNX2	6	17	23	451.565
#409	HOXD12	6	15	21	739.387
#410	TCF25	6	14	20	1003.565
#411	NFYA	6	12	18	360.837
#412	SOX5	6	18	24	1087.699
#413	MNT	6	15	21	347.234
#414	SCRT1	6	17	23	1013.458
#415	HOXD3	6	14	20	508.317
#416	TP63	6	12	18	439.856
#417	HOXA1	6	14	20	2245.072
#418	TCF21	6	11	17	1301.525
#419	EHF	6	19	25	502.457
#420	HOXC10	6	12	18	671.557
#421	POU2F1	6	13	19	337.537
#422	NR4A2	6	11	17	178.329
#423	TBX1	6	15	21	965.663
#424	ETV5	6	14	20	425.89
#425	PKNOX2	6	20	26	1486.043
#426	RARA	6	6	12	521.675
#427	RUNX1T1	6	14	20	257.791
#428	FOXO4	6	12	18	545.119
#429	HMGB2	6	11	17	716.498
#430	POU4F3	5	23	28	1290.072
#431	EN2	5	11	16	337.439
#432	MAFG	5	15	20	791.047
#433	EMX1	5	17	22	759.882
#434	ZSCAN12	5	20	25	1619.986
#435	IRF5	5	16	21	672.134
#436	HOPX	5	17	22	763.399
#437	CREBZF	5	18	23	585.167
#438	HMGA2	5	13	18	629.088
#439	BACH1	5	18	23	1077.219
#440	HOXD4	5	15	20	182.373
#441	HES5	5	13	18	330.165
#442	HOXD10	5	16	21	444.676
#443	HNF4A	5	16	21	1111.229
#444	GLIS3	5	11	16	280.936
#445	HES1	5	16	21	968.219
#446	MLL	5	15	20	1869.85
#447	FOXD1	5	22	27	2401.995
#448	NFE2L2	5	15	20	559.693
#449	FOXP2	5	21	26	922.365
#450	NR2F6	5	9	14	352.046
#451	FLI1	5	12	17	814.63
#452	RUNX1	5	19	24	1135.725
#453	RORA	5	14	19	823.353
#454	LHX5	4	19	23	1807.455
#455	FOXE1	4	18	22	562.459
#456	POU3F3	4	19	23	556.167
#457	ONECUT1	4	19	23	560.844
#458	FOXA3	4	16	20	356.216
#459	ZFHX3	4	16	20	728.175
#460	PROX1	4	14	18	2656.234
#461	IKZF3	4	10	14	328.482
#462	ZSCAN10	4	20	24	593.033
#463	ETV3	4	14	18	604.517
#464	CDX2	4	17	21	794.797
#465	NR1I3	4	14	18	367.738
#466	PAX3	4	16	20	1203.994
#467	MYC	4	16	20	289.249
#468	PDX1	4	13	17	300.674
#469	PEG3	4	22	26	1485.47
#470	ASCL1	4	14	18	534.404
#471	MKX	4	23	27	775.099
#472	TLX2	4	12	16	349.095
#473	LZTS1	4	14	18	620.019
#474	MZF1	4	18	22	579.38
#475	KLF12	4	16	20	292.57
#476	HEYL	3	16	19	987.464
#477	ESX1	3	21	24	883.455
#478	VSX1	3	18	21	497.645
#479	FOXE3	3	17	20	634.923
#480	PAX8	3	16	19	508.932
#481	PITX1	3	22	25	221.067
#482	GATA1	3	12	15	297.58
#483	SMAD9	3	17	20	444.354
#484	NKX3-1	3	19	22	378.299
#485	FOXL1	2	20	22	351.486
#486	LASS5	2	16	18	183.887
#487	FOXN4	2	19	21	729.441
#488	CRX	2	18	20	383.791
#489	TP73	2	18	20	755.089
#490	GATAD2A	2	17	19	772.391
#491	HOXA2	2	13	15	485.27
#492	GATA5	2	17	19	630.011
#493	ZNF219	2	16	18	311.997
#494	TFDP3	2	18	20	183.943
#495	KLF2	1	20	21	122.066
#496	HAND2	1	20	21	659.775
#497	FOXA2	1	11	12	243.332
#498	IKZF1	1	18	19	227.177
#499	NR2E1	1	21	22	88.552
#500	TEF	0	18	18	0