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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	TEAD4	66	4	70	1706.98
#2	MYNN	58	9	67	6894.148
#3	TSC22D3	54	2	56	614.09
#4	NFKB1	54	2	56	197.064
#5	CEBPB	54	1	55	34.142
#6	SOX8	51	4	55	213.077
#7	CTBP1	51	4	55	246.134
#8	RBCK1	49	3	52	662.593
#9	MNX1	48	7	55	1778.74
#10	GRHL2	46	4	50	8256.963
#11	HDAC2	45	7	52	2976.042
#12	TULP4	45	4	49	4136.466
#13	UBP1	43	4	47	1765.915
#14	NR1H3	42	5	47	997.707
#15	ATF5	40	4	44	6444.679
#16	DDIT3	39	6	45	1234.324
#17	PEG3	39	9	48	634.503
#18	HOXC13	39	11	50	1266
#19	HOXB5	38	7	45	997.553
#20	FOXO3	37	5	42	310.78
#21	ZNF277	36	6	42	2935.568
#22	BCL11B	35	6	41	3024.327
#23	CEBPD	34	8	42	1087.007
#24	LHX2	34	7	41	861.256
#25	LMO4	34	7	41	21326.256
#26	ZNF18	33	6	39	1052.582
#27	FOXD4L1	33	8	41	644.739
#28	HES6	32	15	47	2862.799
#29	MYT1	32	9	41	433.394
#30	SLC26A3	31	6	37	206.539
#31	ZIC2	31	4	35	340.442
#32	SNAPC4	30	4	34	130.466
#33	SALL2	29	7	36	249.815
#34	CREB3L2	29	5	34	943.289
#35	ELF5	29	11	40	2951.991
#36	ELF2	28	8	36	1714.186
#37	ZHX1	28	7	35	665.745
#38	IRX3	28	7	35	210.051
#39	RFX1	27	7	34	1409.377
#40	HOXB9	27	9	36	2300.2
#41	TSHZ3	26	11	37	1693.564
#42	IRF1	26	7	33	516.976
#43	NFIB	25	9	34	693.418
#44	GATA2	25	11	36	1687.864
#45	MECOM	25	8	33	699.802
#46	TCFL5	24	8	32	642.109
#47	CBFA2T2	24	8	32	237.346
#48	STRN3	24	9	33	211.854
#49	SNAI2	23	9	32	589.837
#50	JDP2	23	12	35	32677.925
#51	ATF3	22	10	32	7362.704
#52	MYC	22	12	34	5319.033
#53	TWIST1	21	10	31	2212.148
#54	KLF9	21	7	28	1413.564
#55	MAFB	21	14	35	22311.581
#56	FOXO4	20	12	32	4808.026
#57	ZRANB2	20	12	32	1413.549
#58	ATF4	20	10	30	45437.949
#59	FOXD4	20	6	26	400.969
#60	SMAD5	20	10	30	5878.065
#61	TSC22D1	20	11	31	734.346
#62	REXO4	19	6	25	1038.255
#63	TFAP2A	19	8	27	311.042
#64	CEBPA	19	8	27	354.994
#65	SLC30A9	19	4	23	710.292
#66	LZTR1	19	11	30	25259.073
#67	TFDP1	19	7	26	588.154
#68	FOXD1	19	9	28	5471.135
#69	NFE2L3	18	11	29	832.261
#70	PKNOX2	18	9	27	357.97
#71	MESP1	18	14	32	50585.468
#72	TBX15	18	8	26	440.584
#73	KLF11	18	17	35	5992.672
#74	ATF6	18	12	30	3570.507
#75	SNAPC5	17	10	27	317.163
#76	HDAC1	17	9	26	692.476
#77	HOXA10	17	8	25	347.545
#78	SREBF2	17	6	23	2061.602
#79	AHCTF1	17	9	26	584.905
#80	LEF1	17	10	27	6646.699
#81	HOXC4	17	10	27	1295.613
#82	PCGF2	16	7	23	286.568
#83	CREB3L4	16	9	25	4656.263
#84	RXRB	16	7	23	4012.154
#85	NPAS1	16	16	32	4895.948
#86	ISX	16	8	24	1743.676
#87	NOTCH1	16	8	24	154.57
#88	ELK4	16	10	26	382.207
#89	LASS6	16	11	27	466.216
#90	ZNF83	16	7	23	1837.301
#91	KLF5	16	5	21	95.841
#92	FOXJ2	16	8	24	1302.49
#93	ZNF24	16	13	29	2976.829
#94	MNT	15	13	28	16440.204
#95	ZFHX3	15	12	27	2225.385
#96	ZNF91	15	11	26	4932.374
#97	RARA	15	12	27	817.164
#98	ZNF446	15	9	24	231.754
#99	SIX4	15	13	28	7539.316
#100	BCL6	15	8	23	4091.644
#101	NFYC	15	10	25	3653.877
#102	E2F2	14	9	23	97766.913
#103	XBP1	14	9	23	21766.757
#104	TRPS1	14	13	27	633.231
#105	EHF	14	11	25	1440.998
#106	SCMH1	14	9	23	3355.357
#107	CSRNP1	14	12	26	1248.676
#108	RFX5	14	13	27	62850.952
#109	HOXA5	13	12	25	356.22
#110	IRX5	13	13	26	506.149
#111	ETV6	13	10	23	1083.092
#112	HIF1A	13	8	21	1109.544
#113	HOXB13	13	12	25	392.413
#114	KDM5B	13	9	22	1781.945
#115	ECSIT	13	7	20	86.456
#116	SNAPC2	13	15	28	2723.208
#117	KLF6	13	12	25	8325.362
#118	AR	13	8	21	1068.308
#119	ZFPM1	13	12	25	639.69
#120	NFIL3	13	10	23	20524.438
#121	ZNF193	12	10	22	6966.095
#122	AATF	12	6	18	746.184
#123	PHF5A	12	11	23	312.974
#124	HOPX	12	9	21	1352.073
#125	PURA	12	10	22	319.181
#126	IRX6	12	11	23	2821.475
#127	YEATS4	12	8	20	992.655
#128	ZSCAN21	12	6	18	164.978
#129	SIX5	12	8	20	745.182
#130	TBP	12	8	20	416.14
#131	MLX	12	7	19	170.206
#132	LHX6	12	10	22	2014.817
#133	CSRNP2	12	18	30	2869.711
#134	MTA1	11	8	19	202.674
#135	KLF15	11	12	23	290.181
#136	AFF4	11	11	22	5081.845
#137	ADNP	11	14	25	1143.285
#138	FOXD4L5	11	7	18	1226.713
#139	DBP	11	9	20	86.776
#140	MEIS1	11	11	22	2140.3
#141	PBX1	11	11	22	252.427
#142	FUBP1	11	9	20	202.715
#143	NKX3-2	11	8	19	165.133
#144	E2F1	11	15	26	7369.821
#145	PHTF1	11	11	22	1117.698
#146	CNBP	11	9	20	1186.05
#147	TCF12	11	7	18	6299.709
#148	C1orf85	11	11	22	2428.995
#149	CITED2	11	11	22	23130.464
#150	NFIX	11	11	22	825.39
#151	PPARG	11	10	21	2291.332
#152	CTCF	10	9	19	703.623
#153	CREBZF	10	14	24	3947.925
#154	ZNF628	10	14	24	1732.642
#155	TGIF2	10	10	20	162.984
#156	EOMES	10	12	22	450.379
#157	ZNF213	10	10	20	1990.23
#158	CREM	10	10	20	967.258
#159	BLZF1	10	9	19	641.789
#160	BUD31	10	8	18	823.667
#161	ETS2	10	8	18	15562.147
#162	HINFP	10	9	19	762.656
#163	FOXN2	10	9	19	592.666
#164	GABPB1	10	11	21	662.253
#165	ZNF189	10	13	23	6578.581
#166	ZNF75D	10	10	20	560.072
#167	ZKSCAN1	10	10	20	296.865
#168	TSC22D2	9	10	19	228.566
#169	SOX9	9	12	21	7042.137
#170	ZSCAN29	9	9	18	1982.123
#171	POU5F2	9	9	18	1570.679
#172	SIM2	9	10	19	459.67
#173	BTG2	9	14	23	1276.91
#174	GTF2I	9	9	18	1874.309
#175	ARNT2	9	8	17	2408.828
#176	ZNF219	9	6	15	542.234
#177	PDX1	9	8	17	2110.271
#178	ZSCAN5A	9	15	24	3697.286
#179	MYPOP	9	10	19	1463.853
#180	TADA3	9	10	19	308.678
#181	PTTG1	9	12	21	107363.063
#182	ZNF135	9	16	25	1395.471
#183	TGIF1	9	12	21	421.902
#184	IRF7	9	6	15	120.043
#185	DMRT1	9	11	20	1305.568
#186	ZNF323	9	14	23	1516.366
#187	CDKN2A	8	11	19	2326.519
#188	ISL2	8	9	17	214.873
#189	TCF20	8	7	15	3602.829
#190	RORA	8	9	17	3771.525
#191	ARID4A	8	13	21	1360.079
#192	ETV1	8	13	21	888.774
#193	ZNF133	8	10	18	680.032
#194	SLC2A4RG	8	9	17	561.168
#195	TCF25	8	10	18	54.792
#196	ELF3	8	9	17	116.066
#197	JUN	8	11	19	364.837
#198	PITX1	8	11	19	271.865
#199	PLAGL2	8	8	16	152.883
#200	STAT2	8	9	17	1670.968
#201	NFYA	8	14	22	1492.611
#202	NR2C2	8	11	19	454.313
#203	HOMEZ	8	9	17	497.134
#204	TSHZ1	8	8	16	407.333
#205	HCLS1	8	9	17	1145.587
#206	E2F3	8	10	18	1623.095
#207	STAT5B	8	8	16	1144.876
#208	ZNF236	8	12	20	3021.057
#209	FOXP1	8	6	14	76.393
#210	NFX1	8	18	26	7588.767
#211	PHF1	8	10	18	501.539
#212	PA2G4	8	11	19	197.038
#213	NPAS2	8	7	15	1211.469
#214	GABPA	8	10	18	289.97
#215	CUX1	7	8	15	944.731
#216	ZFP36L1	7	12	19	2958.303
#217	ESRRG	7	9	16	1395.502
#218	TBX1	7	16	23	423.802
#219	MSL3	7	12	19	215.933
#220	E2F7	7	14	21	869.591
#221	ZNF138	7	7	14	157.602
#222	ZSCAN2	7	9	16	573.828
#223	HES1	7	11	18	191.738
#224	TEF	7	12	19	975.469
#225	TBX10	7	9	16	846.589
#226	SP4	7	15	22	2563.668
#227	PCGF6	7	11	18	2166.31
#228	SMAD1	7	10	17	1739.103
#229	CSRNP3	7	10	17	232.81
#230	ZNF140	7	12	19	4772.622
#231	FBXW7	7	12	19	433.758
#232	RBPJ	7	13	20	1558.718
#233	NFIC	7	9	16	1121.87
#234	CREBBP	7	12	19	437.951
#235	RFXANK	7	13	20	478.258
#236	ZNF202	7	7	14	456.451
#237	BSX	7	15	22	2848.94
#238	NR5A2	7	10	17	1037.078
#239	ZNF197	7	11	18	2063.378
#240	IRX1	7	10	17	638.306
#241	EN1	7	12	19	1749.32
#242	FOXC2	7	7	14	975.823
#243	ASCL2	6	7	13	612.036
#244	TBX3	6	8	14	384.534
#245	RUNX3	6	15	21	27918.624
#246	HOXC6	6	10	16	2352.711
#247	POU2F3	6	10	16	2264.53
#248	TRIM28	6	9	15	194.802
#249	ETV2	6	6	12	197.144
#250	ZNF19	6	11	17	1012.73
#251	ZNF132	6	8	14	231.239
#252	FOS	6	7	13	208.095
#253	PURB	6	11	17	410.558
#254	MYCL1	6	7	13	584.741
#255	KLF2	6	13	19	247.568
#256	ZNF268	6	12	18	1166.269
#257	NFE2L2	6	13	19	6064.949
#258	ZNF33B	6	9	15	547.611
#259	TFAP2C	6	9	15	212.498
#260	TBX6	6	10	16	4712.841
#261	NPAT	6	9	15	697.714
#262	MAF	6	12	18	121.806
#263	IRX2	6	8	14	82.29
#264	ZNF232	6	10	16	442.575
#265	ZNF367	6	15	21	2573.294
#266	TEAD3	6	11	17	968.943
#267	ARID3A	6	10	16	1103.923
#268	FOXG1	6	10	16	767.548
#269	PAX6	6	12	18	2629.759
#270	FOXP4	6	12	18	1250.809
#271	ELF1	6	12	18	795.163
#272	STAT3	6	10	16	841.255
#273	POU5F1	6	7	13	155.764
#274	PLSCR1	6	10	16	331.981
#275	BHLHE40	6	9	15	18866.574
#276	HOXB7	6	11	17	723.582
#277	HSF2	6	12	18	548.494
#278	ZNF3	6	9	15	2407.198
#279	ZKSCAN2	6	10	16	3985.972
#280	ZNF148	6	11	17	2205.508
#281	ZNF174	6	10	16	5942.227
#282	HLF	6	9	15	1163.848
#283	RFX3	6	9	15	104.379
#284	KLF4	6	5	11	160.117
#285	VAX2	6	13	19	6192.122
#286	CIR1	6	9	15	507.417
#287	SMAD9	6	8	14	2273.735
#288	HOXA3	6	9	15	1039.907
#289	SP3	6	12	18	1315.951
#290	ZHX3	6	5	11	415.927
#291	TCF7	6	14	20	2031.41
#292	NR4A3	6	10	16	4005.468
#293	HES5	6	10	16	709.097
#294	NOLC1	5	9	14	139.359
#295	FOXD2	5	10	15	532.918
#296	ZNF93	5	18	23	2305.603
#297	NFATC3	5	15	20	1394.325
#298	RXRA	5	10	15	1053.476
#299	STAT6	5	10	15	1721.047
#300	ZKSCAN3	5	13	18	914.61
#301	NKX1-1	5	13	18	2725.292
#302	MBD1	5	14	19	952.013
#303	TCEAL1	5	11	16	212.243
#304	NR1D2	5	12	17	360.139
#305	ZNF643	5	11	16	817.818
#306	VAV1	5	13	18	879.293
#307	TFE3	5	8	13	160.824
#308	SNAI3	5	10	15	657.236
#309	ZNF70	5	12	17	4954.45
#310	SPDEF	5	9	14	48.401
#311	GTF2H2	5	8	13	194.814
#312	CREB3	5	15	20	1803.07
#313	SOX13	5	12	17	468.131
#314	BCL3	5	11	16	1411.534
#315	HOXA9	5	11	16	1017.827
#316	MYF5	5	7	12	357.538
#317	HNRNPK	5	12	17	10447.794
#318	POU4F1	5	12	17	1066.778
#319	IRF8	5	12	17	11344.115
#320	FOXO1	5	13	18	165.25
#321	MEF2D	5	9	14	147.537
#322	FEV	5	7	12	68.805
#323	ZXDA	5	11	16	994.868
#324	SOX11	5	15	20	246.049
#325	SOX10	5	13	18	4615.045
#326	FOSL1	5	10	15	89554.083
#327	NR2C1	5	13	18	268.797
#328	TBX21	5	10	15	1090.008
#329	AEBP1	5	7	12	775.769
#330	TBX22	5	16	21	1148.176
#331	HOXA6	5	12	17	94445.563
#332	KLF12	5	12	17	2373.136
#333	E2F8	5	9	14	207.097
#334	C5orf41	5	13	18	1123.807
#335	EPAS1	5	13	18	744.089
#336	ONECUT2	5	13	18	777.409
#337	ZNF85	5	10	15	418.871
#338	ZNF274	5	16	21	2544.093
#339	HAND1	5	12	17	2696.648
#340	REL	5	14	19	731.65
#341	TCF19	5	10	15	104967.853
#342	KLF10	5	10	15	345.149
#343	TCF7L2	5	10	15	1604.415
#344	HOXC8	5	7	12	281.849
#345	THRB	5	4	9	55.465
#346	HMG20B	4	12	16	151.49
#347	ZFHX4	4	7	11	90.972
#348	POU2F1	4	11	15	287.553
#349	ZNF92	4	9	13	177.498
#350	SOX4	4	10	14	342.555
#351	NFYB	4	7	11	827.26
#352	SCRT2	4	13	17	19731.838
#353	NFE2L1	4	8	12	441.094
#354	PBX4	4	9	13	815.841
#355	ZSCAN16	4	11	15	352.038
#356	MAX	4	11	15	1863.043
#357	SOX15	4	6	10	192.967
#358	ZNF165	4	17	21	1275.22
#359	PGBD1	4	10	14	286.318
#360	SIX3	4	10	14	207.269
#361	GTF2IRD1	4	9	13	130.121
#362	NCOR1	4	8	12	233.245
#363	HMG20A	4	14	18	2204.466
#364	TAF13	4	16	20	248.47
#365	FOXQ1	4	5	9	125.203
#366	RCAN1	4	11	15	1349.896
#367	ZNF438	4	8	12	44.806
#368	WT1	4	14	18	1760.238
#369	ZXDC	4	9	13	328.937
#370	TAF4B	4	13	17	163.563
#371	CBL	4	9	13	311.159
#372	GLI3	4	12	16	67.391
#373	VDR	4	14	18	542.421
#374	ZHX2	4	14	18	269.442
#375	MTF1	4	12	16	121.784
#376	HSF1	4	8	12	522.698
#377	IKZF3	4	6	10	75.665
#378	ISL1	4	4	8	53.883
#379	DRAP1	4	13	17	695.718
#380	CREB5	4	9	13	191.189
#381	RCOR2	4	13	17	811.008
#382	RXRG	4	14	18	890.883
#383	HIF3A	4	11	15	4014.441
#384	NR5A1	4	11	15	223.38
#385	ZBTB25	4	11	15	152.678
#386	FOXK1	4	10	14	3875.978
#387	MLL	4	12	16	283.552
#388	ATF1	4	8	12	397.678
#389	ZNF187	4	10	14	800.78
#390	MEIS3	4	7	11	865.311
#391	SIX2	4	12	16	1267.228
#392	STAT1	4	10	14	563.849
#393	SOX30	4	13	17	451.295
#394	SMAD3	4	8	12	652.525
#395	CEBPE	4	8	12	746.581
#396	DLX3	4	12	16	197.678
#397	LHX3	4	14	18	1636.558
#398	HESX1	4	13	17	2791.992
#399	WNT5A	4	10	14	461.976
#400	HEY1	3	9	12	44.25
#401	TBX5	3	10	13	834.055
#402	NME2	3	12	15	178.853
#403	TARDBP	3	10	13	66.666
#404	DLX1	3	14	17	477.413
#405	NR0B1	3	11	14	1899.115
#406	NR1H2	3	15	18	1052.986
#407	PRRX2	3	7	10	100.897
#408	ZNF155	3	10	13	905.07
#409	TFAP4	3	9	12	89.428
#410	ZNF500	3	16	19	957.498
#411	BATF3	3	8	11	35.511
#412	ARNTL2	3	12	15	608.395
#413	FOXN4	3	10	13	93.126
#414	PAX7	3	14	17	987.166
#415	RUNX2	3	8	11	598.279
#416	LCOR	3	12	15	596.566
#417	ATOH1	3	15	18	654.814
#418	PITX3	3	12	15	965.092
#419	ALS2CR8	3	20	23	1274.421
#420	MLLT10	3	11	14	121.574
#421	THRA	3	10	13	201.23
#422	TCF7L1	3	11	14	1035.844
#423	SCRT1	3	16	19	4343.282
#424	GBX2	3	8	11	913.72
#425	HSF4	3	10	13	945.872
#426	TADA2A	3	8	11	699.691
#427	TRERF1	3	13	16	64.209
#428	ETS1	3	5	8	54.312
#429	PRDM1	3	12	15	242.332
#430	MXD1	3	9	12	52.241
#431	HOXA7	3	11	14	947.126
#432	ZBTB17	3	7	10	102.363
#433	ZNF238	3	9	12	1155.098
#434	MAFG	3	11	14	1082.192
#435	IRF4	3	12	15	2664.5
#436	ZNF444	3	13	16	461.568
#437	MYBL2	3	10	13	817.061
#438	SOX21	3	10	13	92.369
#439	ZNF496	3	12	15	3289.043
#440	SOX2	2	11	13	225.799
#441	HDX	2	12	14	3020.583
#442	HHEX	2	11	13	279.676
#443	EGR1	2	14	16	563.159
#444	DMTF1	2	8	10	586.162
#445	CNOT7	2	9	11	391.502
#446	NR4A1	2	11	13	4101.126
#447	ARNTL	2	10	12	42.095
#448	CITED1	2	9	11	80.906
#449	CREB1	2	14	16	2437.053
#450	NR3C2	2	7	9	55.257
#451	ERF	2	13	15	899.414
#452	ZNF157	2	10	12	11134.118
#453	SP140	2	15	17	546.843
#454	NR1D1	2	12	14	1151.82
#455	FLI1	2	8	10	79.117
#456	KCNH8	2	8	10	54.763
#457	GTF2H4	2	14	16	157.7
#458	SPI1	2	13	15	402.059
#459	OTX1	2	15	17	2332.364
#460	NR1I2	2	12	14	1133.735
#461	HOXC12	2	10	12	131.057
#462	TFDP2	2	10	12	85.389
#463	POU3F4	2	9	11	536.914
#464	SATB2	2	11	13	50.194
#465	MYCN	2	9	11	654.803
#466	IRF6	2	12	14	107.22
#467	LHX4	2	8	10	300.645
#468	VENTX	2	8	10	1185.595
#469	GSC	2	9	11	37.249
#470	FOXJ3	2	9	11	46.735
#471	PBX3	2	4	6	20.076
#472	SIX1	2	12	14	3359.094
#473	FOXM1	2	7	9	108.247
#474	CLOCK	2	15	17	424.763
#475	CTNNB1	2	14	16	913.615
#476	HOXC9	2	11	13	22.637
#477	SPIC	2	9	11	68.952
#478	MSX2	2	12	14	3661.013
#479	FOXE1	2	11	13	1638.405
#480	ELF4	2	11	13	174.976
#481	EDF1	2	12	14	211.382
#482	ARNT	2	13	15	37.102
#483	VSX2	2	14	16	898.537
#484	GATAD1	2	13	15	106.662
#485	RORC	2	9	11	48.357
#486	OVOL1	2	13	15	669.171
#487	STAT5A	2	11	13	72.77
#488	CRX	1	11	12	1783.437
#489	NR3C1	1	9	10	191.415
#490	ETV3	1	9	10	188.33
#491	CREB3L3	1	12	13	87.433
#492	GAS7	1	14	15	1067.39
#493	FOXA3	1	9	10	99.953
#494	IKZF4	1	10	11	155.989
#495	KLF7	1	12	13	164.673
#496	HOXB6	1	10	11	29.17
#497	NFIA	0	9	9	0
#498	SOLH	0	11	11	0
#499	TGIF2LY	0	15	15	0
#500	FOXD4L4	0	6	6	0