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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ONECUT2	78	7	85	1138.321
#2	GSX1	69	4	73	208.52
#3	STAT5B	66	10	76	6003.767
#4	ZHX2	66	6	72	1133.05
#5	PAX8	58	1	59	42.811
#6	NKX1-1	52	3	55	98.697
#7	HIF3A	51	4	55	1023.78
#8	ZNF187	45	3	48	1149.872
#9	GAS7	44	6	50	4426.859
#10	FOSL1	43	8	51	726.122
#11	FOXM1	42	6	48	5791.915
#12	HCFC1	41	10	51	23910.157
#13	SPDEF	40	7	47	20995.834
#14	CREB3L1	37	6	43	1940.354
#15	GATAD2B	35	6	41	1345.518
#16	FOXF2	33	7	40	7929.324
#17	VDR	33	5	38	2290.261
#18	NOTCH1	32	8	40	9041.833
#19	FOXA2	32	9	41	22611.213
#20	MYOG	31	6	37	155.867
#21	HMGA1	31	6	37	24926.572
#22	NR6A1	31	7	38	1999.395
#23	ZNF236	31	5	36	349.445
#24	STAT1	31	8	39	1594.355
#25	UHRF1	31	5	36	6019.361
#26	SOX8	31	8	39	1005.507
#27	ARNT	30	10	40	1139.791
#28	HMBOX1	30	6	36	1080.467
#29	TFAP4	30	9	39	569.688
#30	POU6F1	30	6	36	277.584
#31	LZTS1	30	17	47	18440.86
#32	NKX3-1	29	11	40	1800.023
#33	ZNF93	28	7	35	492.96
#34	MGA	28	6	34	1556.083
#35	TCF25	28	7	35	895.115
#36	FOXO1	27	6	33	389.916
#37	CEBPA	27	9	36	2169.193
#38	IRF9	25	10	35	2834.57
#39	C5orf41	24	7	31	531.405
#40	ETS1	23	8	31	1342.958
#41	CITED1	23	12	35	13273.409
#42	TSHZ2	23	7	30	21815.871
#43	SOX6	23	6	29	422.296
#44	TLX3	23	10	33	292.253
#45	PITX3	23	4	27	316.695
#46	SPIB	23	7	30	1772.272
#47	TBX3	23	9	32	10174.038
#48	TRERF1	22	14	36	38792.455
#49	KLF12	22	7	29	3879.196
#50	BTG2	22	12	34	2075.865
#51	IKZF4	22	8	30	2651.215
#52	SOX7	22	9	31	7170.411
#53	ZNF175	22	11	33	3165.718
#54	MAX	21	9	30	1702.211
#55	MSL3	21	11	32	2172.821
#56	HMGB1	21	7	28	1025.086
#57	BACH1	21	10	31	1108.753
#58	KLF7	21	8	29	3276.922
#59	FOXN3	21	10	31	406.444
#60	MEIS1	21	11	32	2824.638
#61	DDIT3	21	5	26	201.325
#62	HOXA7	20	5	25	40941.937
#63	E2F1	20	6	26	275.13
#64	TAF5	19	10	29	1508.138
#65	EGR1	19	10	29	773.249
#66	FEV	19	5	24	1008.342
#67	KLF2	19	9	28	1448.684
#68	TCF19	19	10	29	1621.544
#69	EVX1	18	4	22	1212.438
#70	WT1	18	9	27	1493.845
#71	ENO1	18	9	27	1236.65
#72	NRL	18	8	26	200.881
#73	NFIX	17	10	27	12906.857
#74	CBL	17	9	26	2130.496
#75	MAF	17	9	26	3796.756
#76	NR2C1	17	11	28	832.477
#77	HNF1B	17	11	28	1214.521
#78	PRDM2	17	9	26	1546.867
#79	SP3	17	9	26	2301.848
#80	ZNF154	16	8	24	1656.861
#81	MAFF	16	12	28	5604.597
#82	HOXB7	16	12	28	3209.213
#83	PAX5	16	6	22	1739.175
#84	RAX	16	5	21	195.166
#85	E2F7	16	8	24	932.905
#86	TFCP2	16	6	22	410.24
#87	FOSL2	16	10	26	2438.729
#88	E2F4	16	10	26	988.947
#89	LMX1B	16	10	26	722.957
#90	NANOG	15	9	24	781.766
#91	FOXK1	15	7	22	999.894
#92	SOX10	15	9	24	1354.413
#93	SMAD5	15	10	25	991.584
#94	GATAD2A	15	9	24	212.167
#95	MLXIPL	15	10	25	174.736
#96	TBX2	15	12	27	342.458
#97	STAT2	15	10	25	21101.533
#98	FOXH1	15	10	25	4091.297
#99	NFATC2	14	9	23	2981.41
#100	BNC1	14	7	21	17343.71
#101	SMAD3	14	8	22	2813.716
#102	SRF	14	8	22	713.915
#103	PA2G4	14	11	25	3007.239
#104	FOXK2	14	5	19	5950.566
#105	MEF2C	13	8	21	2401.698
#106	MEIS3	13	8	21	209.965
#107	SOX9	13	9	22	1609.367
#108	TRIM29	13	7	20	1887.837
#109	LHX9	13	9	22	14182.767
#110	NOLC1	13	9	22	3155.343
#111	KLF15	13	12	25	1516.508
#112	ARNT2	13	10	23	1394.729
#113	MYF6	13	12	25	316.467
#114	MBD1	13	8	21	1584.805
#115	HSF4	13	10	23	1134.617
#116	FUBP1	13	11	24	672.836
#117	RORA	13	6	19	1210.224
#118	JDP2	13	11	24	1920.764
#119	PHTF1	13	9	22	987.256
#120	PBX4	13	12	25	575.413
#121	BHLHE41	12	7	19	451.93
#122	TAF13	12	9	21	1536.119
#123	MLX	12	6	18	1569.632
#124	PURB	12	13	25	24065.774
#125	MMP14	12	10	22	3139.439
#126	ASCL1	12	7	19	425.299
#127	ETV6	12	6	18	227.314
#128	SMAD2	12	5	17	6061.799
#129	TFDP1	12	10	22	15130.654
#130	ELK3	12	7	19	2521.468
#131	TBP	12	10	22	3763.792
#132	TCF7L1	12	10	22	3436.416
#133	TWIST2	11	7	18	13470.524
#134	MYCL1	11	13	24	6469.151
#135	ELK1	11	8	19	1064.282
#136	RUNX1T1	11	10	21	864.666
#137	HSF2	11	11	22	1608.817
#138	ELF3	11	10	21	1720.482
#139	ERG	11	6	17	2354.422
#140	PRDM1	11	3	14	30.308
#141	PGBD1	11	13	24	2561.703
#142	SOX17	11	10	21	9884.274
#143	ETV5	11	10	21	1514.538
#144	FOXP1	11	8	19	847.763
#145	AFF1	11	11	22	254.521
#146	EHF	11	10	21	2331.734
#147	ARNTL2	11	7	18	2658.459
#148	HOXD8	10	7	17	606.785
#149	IRF6	10	9	19	1331.939
#150	HDX	10	5	15	414.867
#151	MXD1	10	6	16	549.788
#152	DLX1	10	8	18	1255.423
#153	ZEB1	10	9	19	3218.821
#154	ZNF71	10	4	14	874.574
#155	TCF20	10	7	17	841.001
#156	NFKB1	10	11	21	6523.903
#157	MAFB	10	9	19	17982.319
#158	HCLS1	10	10	20	7089.709
#159	WNT5A	10	10	20	2186.261
#160	ZNF281	10	9	19	3222.23
#161	MYT1	10	12	22	4770.921
#162	SIM2	9	14	23	351.129
#163	PBX3	9	6	15	1423.382
#164	TP73	9	8	17	524.59
#165	PFDN1	9	5	14	701.502
#166	CREB3L2	9	9	18	1132.812
#167	GSC	9	10	19	679.085
#168	ST18	9	10	19	3884.171
#169	GATA4	9	13	22	13017.503
#170	ETS2	9	9	18	1641.985
#171	ZKSCAN2	9	10	19	382.876
#172	ZNF45	9	8	17	635.73
#173	FOXQ1	9	8	17	1006.941
#174	RORC	9	15	24	1193.103
#175	VAV1	9	11	20	4599.183
#176	SPEN	9	8	17	2532.964
#177	HOXA9	9	5	14	2864.937
#178	TFCP2L1	9	8	17	2618.341
#179	XBP1	9	12	21	1034.037
#180	MITF	9	8	17	743.746
#181	ZNF396	9	10	19	661.944
#182	THRA	9	9	18	624.863
#183	PPARA	9	8	17	163.649
#184	ZNF207	8	10	18	11793.426
#185	CREBL2	8	8	16	734.075
#186	BCL6	8	7	15	187.834
#187	FOXR1	8	12	20	951.338
#188	TRIM28	8	10	18	840.644
#189	ESR1	8	13	21	647.226
#190	ESRRA	8	9	17	738.44
#191	MNX1	8	9	17	18185.994
#192	KLF5	8	11	19	1999.17
#193	C11orf9	8	13	21	2301.251
#194	EBF1	8	14	22	1523.456
#195	TCF15	8	8	16	509.956
#196	NFYA	8	11	19	1930.006
#197	ZEB2	8	8	16	3149.803
#198	THRB	8	6	14	497.897
#199	TCF21	8	10	18	3024.594
#200	STAT5A	8	11	19	2437.114
#201	TEAD2	8	9	17	1325.813
#202	TAL1	8	8	16	2823.16
#203	NFE2L1	8	8	16	236.433
#204	GATA3	8	14	22	2984.452
#205	GABPB1	8	7	15	201.954
#206	EPAS1	8	9	17	5267.472
#207	RXRB	8	14	22	3350.123
#208	LHX5	7	10	17	1817.389
#209	TRPS1	7	12	19	4403.696
#210	STAT4	7	10	17	662.928
#211	ASCL2	7	10	17	1486.444
#212	GATA5	7	14	21	5072.799
#213	TEF	7	9	16	3359.134
#214	SMAD4	7	10	17	6213.156
#215	FOS	7	7	14	782.079
#216	IRX3	7	8	15	1047.793
#217	ZNF83	7	7	14	189.337
#218	KLF6	7	10	17	2663.061
#219	ZNF174	7	10	17	4131.189
#220	HOXD9	7	13	20	7059.836
#221	NR5A2	7	10	17	8430.319
#222	TFDP2	7	10	17	1825.913
#223	RARB	7	7	14	3257.856
#224	POU2F2	7	13	20	2636.575
#225	ZFP36L2	7	12	19	887.879
#226	TP63	7	11	18	80.924
#227	PBX1	7	9	16	1972.767
#228	ZNF287	7	7	14	78.036
#229	NFATC4	7	11	18	2223.09
#230	TSC22D2	7	7	14	1272.944
#231	GCFC1	7	6	13	301.343
#232	LHX2	7	10	17	1077.484
#233	TCF4	7	9	16	3697.963
#234	FOXD3	7	10	17	297.821
#235	ZNF19	7	14	21	944.113
#236	CREM	7	8	15	528.807
#237	SIX1	6	10	16	208.776
#238	HOXB9	6	10	16	1274.549
#239	MEIS2	6	9	15	1398.193
#240	ZSCAN5A	6	11	17	2714.514
#241	CEBPD	6	15	21	3982.712
#242	GSX2	6	10	16	337.169
#243	ATF7	6	8	14	292.018
#244	FOXD1	6	11	17	20704.568
#245	ZNF367	6	12	18	2249.488
#246	KLF17	6	8	14	347.753
#247	NKX2-5	6	8	14	1083.692
#248	HOXA10	6	9	15	1026.23
#249	DBP	6	8	14	109.643
#250	TSHZ1	6	9	15	2919.618
#251	STAT3	6	10	16	790.933
#252	HOXB6	6	5	11	1078.534
#253	SLC2A4RG	6	11	17	2919.394
#254	CUX2	6	8	14	14831.566
#255	HMX1	6	8	14	2204.878
#256	ELF2	6	10	16	826.858
#257	CSDA	6	6	12	591.227
#258	HHEX	5	6	11	1505.599
#259	LHX4	5	11	16	941.409
#260	KDM5B	5	10	15	481.623
#261	MESP1	5	6	11	167.084
#262	TRIM22	5	12	17	769.693
#263	ZIC1	5	10	15	6784.908
#264	RUNX1	5	8	13	2815.896
#265	FOSB	5	9	14	1450.441
#266	HOXA2	5	7	12	1300.458
#267	NR2F6	5	8	13	631.418
#268	HLF	5	14	19	2983.036
#269	HMGA2	5	8	13	249.462
#270	SOX18	5	7	12	586.61
#271	NR3C1	5	11	16	477.134
#272	SOX13	5	8	13	1059.658
#273	LMO4	5	8	13	168.736
#274	MYCN	5	13	18	2473.409
#275	KLF9	5	9	14	205.306
#276	HMX2	5	6	11	1959.239
#277	FOXJ2	5	5	10	34.757
#278	GATA6	5	9	14	3036.14
#279	HESX1	5	12	17	615.603
#280	NANOGNB	5	6	11	158.431
#281	JUNB	5	8	13	946.51
#282	ZFPM1	5	8	13	4057.221
#283	NR0B1	5	9	14	369.729
#284	SOX4	5	11	16	994.244
#285	AHR	5	10	15	3369.375
#286	NFE2L2	5	10	15	274.441
#287	MTF1	5	8	13	635.228
#288	SCML1	5	5	10	207.893
#289	ZNF189	4	10	14	410.898
#290	PEG3	4	7	11	213.85
#291	PRRX1	4	9	13	581.124
#292	ZFPM2	4	13	17	4056.026
#293	PAX6	4	13	17	18837.338
#294	HOXD4	4	15	19	8514.981
#295	ETV1	4	8	12	78.579
#296	CSRNP3	4	12	16	648.664
#297	RUNX2	4	8	12	957.607
#298	GLIS3	4	12	16	4662.294
#299	TFAP2C	4	8	12	2206.112
#300	HEY2	4	8	12	214.121
#301	TADA3	4	14	18	3718.302
#302	EGR2	4	12	16	1988.339
#303	HOXB1	4	13	17	444.804
#304	FOXC2	4	10	14	574.089
#305	HEYL	4	9	13	545.1
#306	NPAS2	4	11	15	12853.605
#307	ARX	4	8	12	549.873
#308	HOXB5	4	11	15	106.332
#309	HOXB3	4	10	14	4895.907
#310	ZNF165	4	13	17	709.912
#311	YEATS4	4	11	15	481.488
#312	ESRRG	4	11	15	293.841
#313	AR	4	12	16	2874.644
#314	HOXA11	4	8	12	661.44
#315	NR2F2	4	5	9	1005.252
#316	AFF4	4	7	11	1984.8
#317	ZSCAN12	4	12	16	365.075
#318	HIRA	4	3	7	41.673
#319	CREBBP	4	9	13	60.6
#320	GLI3	4	11	15	1482.505
#321	MLLT10	4	10	14	289.949
#322	BCL11B	4	9	13	379.287
#323	ZNF202	4	12	16	192.94
#324	FOXA1	4	7	11	569.577
#325	HOXA5	4	12	16	340.869
#326	GRHL2	4	8	12	87.609
#327	TFEB	4	6	10	514.871
#328	PLSCR1	4	8	12	236.791
#329	RBPJL	4	8	12	257.034
#330	HAND1	4	12	16	315.714
#331	IRF1	4	8	12	1251.297
#332	ISL1	4	10	14	5463.323
#333	ZNF193	4	11	15	1051.778
#334	SIX4	4	10	14	1257.049
#335	PHF1	4	10	14	310.01
#336	ZSCAN1	4	11	15	566.039
#337	SOX12	4	11	15	703.649
#338	ATF3	4	7	11	2625.345
#339	SP1	3	14	17	594.246
#340	SUPT6H	3	7	10	1800.421
#341	POU1F1	3	8	11	156.437
#342	LHX3	3	7	10	369.175
#343	CNOT7	3	8	11	177.196
#344	SMAD9	3	11	14	1640.209
#345	FOXG1	3	13	16	2263.236
#346	HIC1	3	11	14	40.211
#347	POU3F1	3	11	14	147.657
#348	ZNF85	3	9	12	216.038
#349	ZNF155	3	6	9	448.536
#350	ZIC2	3	16	19	874.225
#351	NR2E1	3	10	13	998.541
#352	FOXJ3	3	13	16	452.157
#353	HOXA3	3	7	10	36777.921
#354	TCFL5	3	8	11	118.702
#355	GATA1	3	10	13	773.552
#356	TFDP3	3	5	8	59.515
#357	BLZF1	3	12	15	344.347
#358	NFX1	3	6	9	72.057
#359	VTN	3	16	19	1016.143
#360	ELF1	3	8	11	1098.91
#361	DLX2	3	10	13	849.062
#362	FOXF1	3	16	19	1636.856
#363	MEOX1	3	12	15	5758.937
#364	POU3F2	3	10	13	137.976
#365	PPARG	3	6	9	2118.36
#366	ZNF628	3	2	5	648.727
#367	FLI1	3	14	17	1155.063
#368	DMBX1	3	11	14	3703.804
#369	GATA2	3	11	14	171.932
#370	SOX30	3	9	12	2543.75
#371	NR4A1	3	14	17	575.614
#372	SOX5	3	10	13	1128.907
#373	HSF1	3	11	14	1030.714
#374	MSX1	3	12	15	956.287
#375	RCAN1	3	10	13	3377.151
#376	NR4A3	3	8	11	303.065
#377	BCL3	3	10	13	4272.927
#378	ZNF80	3	8	11	69.903
#379	CDKN2A	3	14	17	3268.104
#380	PTTG1	3	9	12	528.679
#381	HOPX	3	13	16	338.381
#382	ZNF140	3	10	13	178.61
#383	HOXB2	2	10	12	742.701
#384	OTX2	2	6	8	79.427
#385	HES1	2	11	13	2009.907
#386	NCOR1	2	9	11	971.929
#387	IRF5	2	15	17	2430.425
#388	ZNF33B	2	12	14	165.356
#389	JUN	2	12	14	1031.731
#390	HOXD1	2	9	11	1024.808
#391	RERE	2	12	14	1663.724
#392	HEY1	2	9	11	522.976
#393	ZNF131	2	10	12	68.798
#394	AEBP1	2	11	13	636.158
#395	NFYB	2	9	11	856.427
#396	CTNNB1	2	10	12	348.974
#397	PLAG1	2	6	8	16885.185
#398	RFX3	2	10	12	174.045
#399	USF2	2	12	14	50.19
#400	ZNF277	2	10	12	134.296
#401	HNF4G	2	12	14	403.278
#402	SOX11	2	11	13	1383.414
#403	MSX2	2	8	10	267.713
#404	ZNF639	2	14	16	97.349
#405	KLF4	2	8	10	971.413
#406	SIX3	2	14	16	4621.849
#407	ZNF91	2	9	11	62.524
#408	SATB2	2	5	7	732.746
#409	HOXD3	2	10	12	7065.944
#410	ATF1	2	12	14	996.718
#411	SIM1	2	11	13	247.124
#412	TCF12	2	10	12	1278.727
#413	IRF8	2	7	9	238.729
#414	RUNX3	2	10	12	983.022
#415	ZNF232	2	10	12	131.39
#416	SPIC	2	8	10	863.576
#417	LEF1	2	9	11	1487.963
#418	DLX6	2	11	13	1305.831
#419	KCNH8	2	16	18	2348.624
#420	HOXC4	2	14	16	1866.908
#421	ZSCAN18	2	13	15	924.135
#422	MEOX2	2	14	16	5394.909
#423	ZNF169	2	10	12	571.765
#424	MAFK	2	5	7	63.365
#425	TFEC	2	6	8	1483.223
#426	HOXD13	2	13	15	404.641
#427	LASS6	2	6	8	23.265
#428	BHLHE40	2	11	13	1139.6
#429	RFX5	2	8	10	684.13
#430	TWIST1	2	13	15	4066.114
#431	TFAP2A	2	16	18	1301.554
#432	HOXB8	2	14	16	586.471
#433	TBX20	2	12	14	1841.808
#434	FOXC1	2	12	14	7139.976
#435	E2F3	2	6	8	570.833
#436	FOXL2	1	9	10	89.935
#437	CREB5	1	10	11	1265.738
#438	NR4A2	1	11	12	14013.786
#439	IKZF1	1	9	10	373.648
#440	CITED2	1	10	11	29.778
#441	MYT1L	1	11	12	792.238
#442	HOXD10	1	10	11	20.485
#443	ZSCAN23	1	11	12	2138.363
#444	MKX	1	10	11	1206.787
#445	ZNF117	1	10	11	2025.297
#446	MLL	1	8	9	164.068
#447	FOXN1	1	11	12	90.685
#448	ZNF483	1	11	12	667.049
#449	FOXJ1	1	12	13	87.606
#450	SIX5	1	15	16	1740.625
#451	ZNF496	1	4	5	15.363
#452	MTA3	1	7	8	30.384
#453	ZSCAN20	1	9	10	22.652
#454	HOXC10	1	10	11	234.651
#455	MYC	1	9	10	105.194
#456	EGR3	1	8	9	158.97
#457	POU2F3	1	12	13	52.981
#458	PGR	1	11	12	1259.637
#459	NOBOX	1	12	13	57.174
#460	CREBZF	1	8	9	119.754
#461	HNF4A	1	11	12	102.512
#462	NFIB	1	10	11	565.713
#463	ZNF167	1	9	10	17.933
#464	TBX21	1	9	10	414.539
#465	PTH	1	9	10	1746.444
#466	SNAI2	1	15	16	67.212
#467	ATF2	1	8	9	24.158
#468	NPAT	1	13	14	71.53
#469	MECOM	1	12	13	528.206
#470	FOXL1	1	7	8	55.814
#471	NFIA	1	7	8	73.557
#472	SMAD6	1	11	12	2468.491
#473	SALL1	1	13	14	2206.811
#474	FOXP2	1	12	13	779.868
#475	NEUROD2	1	12	13	34.757
#476	ZNF213	1	9	10	22.112
#477	PITX2	0	12	12	0
#478	SIX2	0	11	11	0
#479	SOX2	0	13	13	0
#480	GRHL3	0	9	9	0
#481	NFATC1	0	7	7	0
#482	NR2F1	0	16	16	0
#483	HES6	0	5	5	0
#484	RARA	0	10	10	0
#485	C12orf28	0	7	7	0
#486	CTBP1	0	9	9	0
#487	LHX1	0	11	11	0
#488	ZNF92	0	12	12	0
#489	ZNF37A	0	12	12	0
#490	ZNF81	0	7	7	0
#491	TCF3	0	8	8	0
#492	E2F8	0	9	9	0
#493	TEAD4	0	10	10	0
#494	TP53	0	10	10	0
#495	TGIF2	0	7	7	0
#496	ZFP42	0	9	9	0
#497	FOXO6	0	10	10	0
#498	MYNN	0	9	9	0
#499	LHX8	0	8	8	0
#500	TBX1	0	13	13	0