Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	MYNN	72	1	73	32.9
#2	ATF1	55	4	59	175.582
#3	PHF1	52	2	54	1740.495
#4	NFIC	51	5	56	248.681
#5	JUND	49	8	57	308.373
#6	YEATS4	47	0	47	0
#7	YBX1	46	7	53	1380.616
#8	KDM5A	45	6	51	1634.386
#9	PPARD	42	7	49	1748.438
#10	STAT3	42	5	47	981.84
#11	TADA3	39	4	43	1385.85
#12	NFATC3	38	6	44	543.28
#13	BUD31	37	7	44	419.323
#14	ZNF277	37	10	47	806.931
#15	TCEAL1	37	5	42	194.781
#16	ELF2	36	4	40	646.193
#17	SMAD2	36	5	41	5811.763
#18	GCFC1	36	3	39	843.5
#19	ZNF148	35	6	41	2606.69
#20	SUPT4H1	34	4	38	1956.817
#21	EPAS1	34	6	40	594.418
#22	CREBL2	34	11	45	2172.386
#23	AATF	34	4	38	134.056
#24	NFKB1	33	6	39	2289.563
#25	NFE2L1	33	5	38	142.502
#26	ZNF639	33	10	43	506.944
#27	ATF7	33	6	39	1077.424
#28	STAT1	32	6	38	236.66
#29	TEAD1	32	4	36	293.28
#30	HCLS1	32	6	38	382.273
#31	MSRB2	31	7	38	4365.808
#32	CEBPB	31	7	38	344.16
#33	FOXN3	31	11	42	1298.733
#34	NR2F2	31	11	42	3389.617
#35	GLIS2	30	4	34	106.683
#36	CREBBP	30	3	33	374.368
#37	CREB3L2	30	8	38	952.019
#38	SNAI2	30	4	34	745.103
#39	SPEN	30	6	36	191.88
#40	MNT	30	8	38	4033.821
#41	AEBP1	29	3	32	497.275
#42	CREM	29	7	36	1202.081
#43	CTBP1	29	6	35	801.609
#44	FLI1	29	5	34	435.268
#45	HNRNPAB	28	7	35	328.824
#46	MAFB	28	10	38	318.454
#47	BCL11B	28	5	33	871.205
#48	ELF4	27	9	36	572.219
#49	HNRNPK	27	8	35	753.709
#50	ZNF138	27	10	37	6647.89
#51	ENO1	26	5	31	247.995
#52	SPDEF	26	8	34	7014.826
#53	SOX4	25	6	31	414.962
#54	ZSCAN16	25	12	37	3751.327
#55	FOXP1	25	6	31	839.4
#56	MZF1	25	2	27	162.739
#57	NR2C1	25	10	35	4158.887
#58	ZNF238	25	4	29	399.457
#59	LEF1	24	7	31	1166.466
#60	RFXANK	24	8	32	632.388
#61	FOSL2	24	10	34	2885.519
#62	FOXO3	23	5	28	279.335
#63	NFIB	23	7	30	2538.022
#64	TCF7	23	12	35	1293.75
#65	C1orf85	23	15	38	3003.748
#66	NFIX	23	7	30	637.469
#67	MLL	23	13	36	1070.393
#68	TFAM	23	7	30	2585.352
#69	TCF4	23	14	37	704.769
#70	RELB	23	9	32	4194.532
#71	CUX1	23	7	30	832.39
#72	SNAPC5	22	6	28	73.898
#73	RFX5	22	11	33	1857.111
#74	ZGPAT	22	10	32	670.146
#75	MITF	22	9	31	1495.448
#76	YY1	22	10	32	574.408
#77	UBN1	22	11	33	267.556
#78	RERE	22	9	31	1683.34
#79	PRRX1	22	8	30	843.111
#80	GATA6	22	8	30	266.592
#81	NR1H3	22	10	32	3341.789
#82	NR1H2	21	7	28	354.411
#83	ZNF92	21	13	34	2291.892
#84	KLF9	21	13	34	1308.065
#85	GATAD2B	21	10	31	1850.254
#86	ZFP36L1	21	13	34	2188.666
#87	HMG20B	21	10	31	4951.293
#88	ADNP	21	14	35	2656.361
#89	RUNX1T1	21	7	28	546.017
#90	RBPJ	21	13	34	1220.256
#91	NFIA	20	8	28	747.811
#92	GLI3	20	12	32	1899.483
#93	CEBPD	20	9	29	5339.465
#94	PPARA	20	9	29	2043.362
#95	MEIS1	20	14	34	1747.591
#96	NFIL3	20	9	29	1743.622
#97	ZEB2	20	9	29	1140.136
#98	PHF5A	20	18	38	7762.167
#99	CBFA2T2	20	10	30	2023.749
#100	ZNF140	20	9	29	1368.508
#101	GTF2H3	20	8	28	2937.424
#102	POU5F1B	20	9	29	1826.173
#103	NFE2L2	20	11	31	4720.457
#104	TFE3	20	7	27	1302.947
#105	C2orf3	20	5	25	6211.985
#106	TCF25	20	9	29	1126.941
#107	SP1	19	11	30	1009.683
#108	GATA3	19	13	32	1077.067
#109	CREB1	19	12	31	4510.756
#110	RELA	19	13	32	438.844
#111	HES1	19	13	32	1396.147
#112	PBX1	19	7	26	537.264
#113	DMTF1	19	9	28	436.776
#114	CNOT8	19	9	28	6706.546
#115	SP4	19	12	31	8495.125
#116	TRIM28	19	8	27	773.354
#117	ETV6	19	10	29	1030.423
#118	ZNF217	19	10	29	3461.346
#119	NR3C1	19	9	28	2668.573
#120	FUBP1	19	3	22	224.868
#121	RCOR1	19	16	35	3042.367
#122	GATAD2A	19	12	31	457.006
#123	SMAD1	18	13	31	1711.021
#124	CBL	18	7	25	541.33
#125	HMG20A	18	11	29	1986.992
#126	ZNF207	18	5	23	581.651
#127	RNF4	18	9	27	432.164
#128	ZNF45	18	20	38	5805.637
#129	FOXO1	18	11	29	3084.756
#130	NFATC2	18	9	27	576.629
#131	ETS1	18	10	28	544.541
#132	HHEX	18	14	32	7208.796
#133	STAT2	17	11	28	1262.172
#134	NFAT5	17	10	27	2620.187
#135	KLF3	17	14	31	3323.635
#136	IRF4	17	11	28	740.441
#137	CSDA	17	6	23	154.242
#138	TFEB	17	12	29	2864.499
#139	TBP	17	9	26	1782.67
#140	TFDP1	17	12	29	477.464
#141	ZRANB2	17	8	25	2375.909
#142	RUNX3	17	11	28	1418.845
#143	KLF11	16	18	34	3644.812
#144	TCF3	16	13	29	2549.155
#145	TAF12	16	10	26	1282.056
#146	HMGA1	16	15	31	4175.857
#147	HMX1	16	7	23	2945.773
#148	CREB3	16	8	24	807.9
#149	KLF7	16	15	31	2411.199
#150	TFEC	16	8	24	5228.234
#151	NOLC1	16	11	27	316.905
#152	TP53	15	10	25	830.255
#153	FOXC1	15	18	33	4403.011
#154	BHLHE40	15	11	26	1151.522
#155	BTAF1	15	12	27	2430.059
#156	PRDM2	15	8	23	259.708
#157	KLF12	15	12	27	775.473
#158	MTA1	15	10	25	4717.07
#159	SREBF2	15	7	22	4350.126
#160	IRF2	15	9	24	1553.431
#161	BRD8	15	12	27	963.119
#162	ARID4A	15	16	31	5181.162
#163	TFDP2	14	19	33	2364.757
#164	NFYB	14	15	29	5507.037
#165	VDR	14	15	29	1539.593
#166	TSHZ3	14	8	22	830.883
#167	ZNF131	14	13	27	3125.36
#168	CTNNB1	14	11	25	391.889
#169	SMAD4	14	9	23	2573.567
#170	NOTCH1	14	17	31	1290.803
#171	PBX2	14	15	29	1207.393
#172	RCAN1	14	12	26	795.039
#173	MEIS2	14	12	26	1328.888
#174	SATB1	14	8	22	1319.892
#175	ZNF91	13	20	33	2015.111
#176	SOLH	13	13	26	2689.367
#177	NFKB2	13	12	25	776.304
#178	NCOR1	13	9	22	1512.035
#179	SPI1	13	12	25	885.324
#180	BLZF1	13	13	26	232.097
#181	DDIT3	13	14	27	1227.754
#182	SIX1	13	17	30	961.596
#183	ZSCAN18	13	16	29	4772.136
#184	TAF4B	13	12	25	812.669
#185	NR2F6	13	10	23	1154.498
#186	ARNTL2	13	10	23	5082.497
#187	ADNP2	13	12	25	3082.086
#188	MLX	13	15	28	7307.754
#189	PFDN1	13	18	31	1956.848
#190	REL	13	12	25	2198.65
#191	ZHX1	13	16	29	5014.049
#192	MEOX2	13	15	28	3554.242
#193	IRF1	12	12	24	2362.596
#194	LCOR	12	10	22	298.051
#195	MLLT10	12	10	22	1359.716
#196	TSC22D2	12	14	26	823.423
#197	FOXM1	12	11	23	485.341
#198	ZNF397	12	16	28	2344.707
#199	FBXW7	12	11	23	442.095
#200	PLAGL2	12	14	26	657.259
#201	CNOT7	12	9	21	1200.723
#202	HOXA3	12	12	24	311.208
#203	RUNX1	12	11	23	3182.188
#204	CITED2	12	12	24	3986.778
#205	UHRF1	12	12	24	1133.968
#206	ZNF85	12	12	24	2710.802
#207	E2F8	12	17	29	3408.622
#208	HMGB1	12	10	22	1773.153
#209	FOXJ3	12	14	26	985.053
#210	PURA	12	10	22	356.581
#211	BACH2	12	16	28	3474.439
#212	AHCTF1	12	18	30	2098.699
#213	MTF1	12	13	25	1720.846
#214	TRIM25	12	9	21	1226.701
#215	CREBZF	12	5	17	1125.048
#216	PBX3	12	16	28	775.969
#217	LZTR1	12	10	22	453.457
#218	EDF1	11	10	21	2205.744
#219	SP140	11	15	26	1340.409
#220	KLF2	11	12	23	1086.452
#221	SIN3A	11	12	23	2019.729
#222	TAL1	11	15	26	3743.743
#223	E2F6	11	16	27	1196.6
#224	JUNB	11	12	23	649.932
#225	STAT6	11	10	21	1598.251
#226	ASCL2	11	7	18	253.774
#227	POU2F2	11	10	21	5331.741
#228	SOX7	11	10	21	860.264
#229	MYBL2	11	9	20	2379.527
#230	ZHX2	11	8	19	1757.313
#231	MAF	11	16	27	923.79
#232	KLF4	11	13	24	6352.401
#233	STAT5A	11	17	28	3163.387
#234	TRIM22	11	13	24	5876.346
#235	HMGB2	11	10	21	3087.051
#236	MEIS3P1	11	11	22	478.001
#237	PRRX2	11	18	29	5699.274
#238	GABPB1	11	11	22	1429.917
#239	ZNF83	11	12	23	1298.314
#240	BTG2	11	11	22	2326.457
#241	ELK3	10	11	21	4993.272
#242	TAF7	10	13	23	4859.875
#243	IRF3	10	8	18	1406.142
#244	NPAT	10	16	26	6831.638
#245	NFYC	10	13	23	2908.272
#246	TGIF1	10	14	24	2578.717
#247	SMAD5	10	13	23	2185.999
#248	ZNF134	10	15	25	599.891
#249	VAV1	10	7	17	121.383
#250	IRF8	10	15	25	1984.82
#251	FOS	10	11	21	3373.845
#252	ZNF236	10	14	24	665.95
#253	BCL3	10	15	25	453.708
#254	CNBP	10	18	28	891.036
#255	PA2G4	10	16	26	1517.58
#256	ELF1	10	16	26	1039.425
#257	PCGF2	10	10	20	247.955
#258	BCL6	9	12	21	885.857
#259	PLSCR1	9	14	23	1026.063
#260	SCML1	9	18	27	3009.372
#261	ZFPM2	9	13	22	9684.633
#262	E2F5	9	12	21	2027.914
#263	BATF3	9	12	21	2180.561
#264	JUN	9	15	24	3085.378
#265	ZFP36L2	9	13	22	358.709
#266	ZNF438	9	9	18	774.53
#267	PRDM1	9	18	27	910.05
#268	ZC3H8	9	16	25	873.232
#269	C5orf41	9	15	24	2188.808
#270	MEF2A	9	18	27	1962.378
#271	TEAD2	9	12	21	3702.733
#272	HOXA2	9	15	24	1326.313
#273	MECOM	9	8	17	549.039
#274	ZNF33A	9	15	24	5993.961
#275	ZNF281	9	22	31	2085.788
#276	CSRNP2	9	14	23	919.674
#277	ZNF232	9	11	20	2666.555
#278	HIF1A	9	13	22	1913.479
#279	PCGF6	9	15	24	579.442
#280	REST	9	7	16	425.61
#281	ZNF449	9	17	26	1954.108
#282	ZNF445	9	8	17	1347.789
#283	RAX2	9	20	29	2523.794
#284	KLF6	8	12	20	847.812
#285	WNT5A	8	14	22	3136.116
#286	TARDBP	8	12	20	906.099
#287	NKX1-1	8	10	18	464.204
#288	SMAD6	8	15	23	736.737
#289	TAF6	8	14	22	829.293
#290	SMAD9	8	15	23	1901.016
#291	ZNF367	8	9	17	342.347
#292	KLF10	8	12	20	1106.92
#293	HSF5	8	14	22	609.601
#294	MAFF	8	19	27	989.308
#295	TCF7L2	8	18	26	2887.299
#296	POU2F1	8	10	18	135.027
#297	HIC1	8	16	24	1200.268
#298	HEY1	8	17	25	1759.733
#299	DBP	8	15	23	1989.195
#300	GABPA	8	17	25	3048.329
#301	TSHZ1	8	15	23	745.376
#302	MAFK	8	15	23	885.613
#303	E2F3	8	14	22	5173.213
#304	ATF5	8	15	23	2149.741
#305	ZKSCAN1	8	14	22	5138.132
#306	STAT4	8	15	23	1122.214
#307	ZNF434	7	16	23	630.227
#308	ZBTB25	7	11	18	1000.66
#309	ETV1	7	16	23	954.475
#310	SCML2	7	12	19	533.999
#311	MMP14	7	14	21	1900.422
#312	CDKN2A	7	10	17	1635.336
#313	PTTG1	7	14	21	2591.618
#314	EGR3	7	15	22	5311.203
#315	SREBF1	7	10	17	2128.938
#316	ZNF202	7	10	17	679.307
#317	CSRNP1	7	19	26	1795.312
#318	RORA	7	16	23	606.788
#319	SP3	7	8	15	457.042
#320	ARNT	7	12	19	679.496
#321	SPIB	7	26	33	1572.188
#322	TCFL5	7	15	22	489.418
#323	MSC	7	18	25	1406.86
#324	ZNF268	7	15	22	1019.869
#325	TAF4	7	10	17	506.408
#326	NFE2L3	7	15	22	1285.592
#327	ERF	7	19	26	2108.842
#328	ZNF33B	7	20	27	360.237
#329	MYC	7	14	21	1864.472
#330	TCF19	7	6	13	231.225
#331	MSL3	7	10	17	751.571
#332	MAFG	7	9	16	214.179
#333	ERG	7	8	15	64.177
#334	BACH1	7	18	25	708.779
#335	PPARG	6	22	28	836.985
#336	EGR1	6	15	21	1980.673
#337	EBF1	6	15	21	2487.815
#338	NR1D2	6	18	24	1398.191
#339	XBP1	6	12	18	1249.461
#340	RUNX2	6	20	26	5602.542
#341	HMBOX1	6	21	27	2333.981
#342	EHF	6	19	25	8027.874
#343	MXD1	6	15	21	568.769
#344	TAF5	6	11	17	2379.558
#345	RXRA	6	11	17	187.399
#346	ZEB1	6	16	22	3809.068
#347	FOXN2	6	15	21	1234.856
#348	GATAD1	6	15	21	1169.094
#349	CREB3L1	6	11	17	251.44
#350	SMAD3	6	14	20	437.429
#351	TSC22D4	6	15	21	834.597
#352	ZNF37A	6	16	22	606.139
#353	SIX5	6	18	24	1063.887
#354	SLC30A9	6	17	23	1899.067
#355	POU6F1	6	10	16	1692.489
#356	LASS2	6	20	26	987.371
#357	TCF20	6	15	21	1917.785
#358	E2F1	6	14	20	3506.425
#359	BATF	5	22	27	2434.705
#360	TULP4	5	12	17	643.545
#361	GTF2H4	5	14	19	398.118
#362	ATF3	5	15	20	3386.947
#363	TWIST1	5	16	21	949.321
#364	DRAP1	5	18	23	1900.907
#365	ZNF394	5	16	21	3079.355
#366	MAX	5	11	16	89.542
#367	BATF2	5	13	18	1160.375
#368	HOXA9	5	17	22	2993.163
#369	NFATC1	5	15	20	115.02
#370	TRPS1	5	11	16	449.183
#371	KDM5B	5	14	19	600.106
#372	ZFP90	5	20	25	3484.922
#373	MGA	5	15	20	289.752
#374	TCF12	5	9	14	666.886
#375	ZFHX3	5	19	24	822.034
#376	SIX4	5	17	22	649.82
#377	PROX1	5	12	17	429.261
#378	NFX1	5	14	19	609.893
#379	TFCP2	5	19	24	1617.269
#380	TCF7L1	5	13	18	319.323
#381	ZXDC	5	14	19	768.995
#382	CLOCK	5	11	16	745.443
#383	LASS6	5	16	21	1134.426
#384	IKZF1	5	12	17	1658.093
#385	TRERF1	5	17	22	660.429
#386	ZNF3	5	14	19	967.624
#387	CEBPA	5	16	21	433.299
#388	FOXK1	5	18	23	223.127
#389	TAF1B	5	16	21	642.712
#390	MSX2	4	15	19	790.018
#391	LMO4	4	23	27	871.719
#392	FOXD1	4	23	27	1540.577
#393	DMRT2	4	13	17	1646.621
#394	SLC2A4RG	4	17	21	1011.543
#395	MESP2	4	12	16	315.592
#396	HEYL	4	12	16	66.882
#397	HOXA5	4	19	23	2714.482
#398	AHR	4	15	19	1293.4
#399	WT1	4	15	19	255.121
#400	IRF9	4	17	21	4789.71
#401	AFF4	4	10	14	409.753
#402	PBX4	4	14	18	223.748
#403	TCF15	4	11	15	322.346
#404	NR4A3	4	19	23	453.854
#405	TBX21	4	12	16	906.233
#406	MEF2C	4	16	20	3259.465
#407	MYPOP	4	12	16	568.676
#408	TWIST2	4	16	20	521.917
#409	ZNF117	4	16	20	473.572
#410	SOX15	4	13	17	699.533
#411	PKNOX1	4	13	17	973.413
#412	GLIS3	4	13	17	47.694
#413	NFXL1	4	18	22	3829.304
#414	ZSCAN2	4	19	23	2005.446
#415	FOSB	4	9	13	191.106
#416	NR2F1	4	13	17	211.512
#417	IRF7	4	13	17	2233.907
#418	SUPT6H	4	18	22	183.232
#419	RBCK1	4	13	17	832.871
#420	TSHZ2	4	14	18	1068.917
#421	MTA3	3	16	19	997.44
#422	ARNT2	3	12	15	76.093
#423	PHTF1	3	13	16	262.828
#424	ETS2	3	19	22	217.544
#425	FOXG1	3	13	16	197.301
#426	STAT5B	3	18	21	1185.854
#427	ZBTB38	3	16	19	917.178
#428	MSX1	3	21	24	513.917
#429	FOXP4	3	10	13	296.876
#430	SOX8	3	16	19	1405.062
#431	E2F2	3	18	21	899.152
#432	HOXC10	3	16	19	2524.582
#433	ZNF24	3	17	20	862.425
#434	NR3C2	3	21	24	456.341
#435	HESX1	3	13	16	516.764
#436	ZBTB48	3	17	20	741.975
#437	HOXD8	3	13	16	183.491
#438	AFF1	3	15	18	332.626
#439	ZNF93	3	15	18	1594.387
#440	BHLHE41	3	13	16	446.203
#441	HOXB9	3	11	14	2403.381
#442	GAS7	3	12	15	269.65
#443	SIX3	3	12	15	699.12
#444	NFATC4	3	15	18	1520.125
#445	HOPX	3	16	19	2187.725
#446	RFXAP	3	18	21	3473.12
#447	ZNF75D	3	13	16	1191.315
#448	TBX5	3	16	19	2188.147
#449	CBFA2T3	3	15	18	840.806
#450	HOXB3	3	22	25	333.955
#451	IKZF4	3	18	21	327.046
#452	NR4A1	2	14	16	236.565
#453	ZNF35	2	17	19	179.292
#454	SPIC	2	17	19	281.309
#455	PLAG1	2	17	19	187.173
#456	EGR2	2	17	19	215.511
#457	HLF	2	20	22	685.132
#458	IRX3	2	16	18	177.64
#459	CIR1	2	18	20	646.889
#460	ATF6	2	12	14	49.771
#461	HOXB2	2	18	20	294.368
#462	RB1	2	12	14	263.26
#463	ETV7	2	19	21	1039.302
#464	SOX9	2	12	14	225.385
#465	TRIM29	2	9	11	577.003
#466	ZNF500	2	19	21	171.242
#467	TSC22D3	2	16	18	1685.222
#468	MEOX1	2	20	22	618.892
#469	NR4A2	2	13	15	2915.524
#470	HOXD4	2	15	17	875.481
#471	TBX1	2	16	18	447.258
#472	ARNTL	2	15	17	158.078
#473	SNAPC4	2	16	18	522.459
#474	PITX1	2	9	11	88.323
#475	ISX	2	22	24	1430.924
#476	HOXC4	2	20	22	2743.465
#477	EOMES	1	21	22	1265.104
#478	ZSCAN12	1	13	14	19.864
#479	ASCL1	1	17	18	1089.387
#480	GTF2H2	1	18	19	52.343
#481	TEF	1	14	15	90.094
#482	FOXF1	1	18	19	105.815
#483	ETV5	1	16	17	48.358
#484	LHX8	1	7	8	72.14
#485	IRF5	1	24	25	1281.725
#486	HOXA10	1	14	15	196.438
#487	IKZF3	1	18	19	1203.853
#488	RARB	1	15	16	1696.504
#489	MYCL1	1	17	18	82.061
#490	FOXQ1	1	17	18	66.756
#491	ZNF274	1	16	17	45.91
#492	CEBPE	1	15	16	673.551
#493	PURB	1	14	15	84.69
#494	HIRA	0	16	16	0
#495	TGIF2	0	15	15	0
#496	FOXP2	0	12	12	0
#497	TSC22D1	0	19	19	0
#498	HOXB7	0	18	18	0
#499	RARA	0	27	27	0
#500	ZSCAN21	0	19	19	0