Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	FLI1	65	5	70	2581.978
#2	NFATC2	56	12	68	1742.254
#3	JUNB	54	5	59	354.912
#4	BCL6	53	2	55	164.348
#5	ZNF238	51	5	56	1741.445
#6	REL	49	16	65	1746.652
#7	HDAC1	46	4	50	291.174
#8	BHLHE40	44	11	55	4375.741
#9	BCL3	43	10	53	2218.396
#10	CUX1	42	4	46	1925.29
#11	HMGB1	42	7	49	505.696
#12	EBF1	40	9	49	740.568
#13	CEBPB	39	9	48	2624.56
#14	POU2F2	39	11	50	1238.401
#15	E2F2	39	8	47	1062.758
#16	TFEB	39	14	53	1488.111
#17	SPI1	39	7	46	268.577
#18	MAX	38	1	39	26.805
#19	MEF2A	38	9	47	1433.735
#20	ETS1	36	4	40	660.147
#21	MEIS2	36	12	48	2795.764
#22	DMTF1	36	7	43	705.696
#23	IRF8	36	13	49	2379.201
#24	BATF3	36	7	43	778.765
#25	ZHX2	35	2	37	92.799
#26	AFF1	35	9	44	610.439
#27	MTA3	34	7	41	1150.177
#28	STAT1	34	10	44	1155.532
#29	BTG2	33	10	43	1087.275
#30	ADNP	33	9	42	1796.285
#31	E2F7	33	10	43	580.623
#32	ZEB1	32	10	42	2123.831
#33	TEAD3	32	4	36	413.933
#34	FOXO1	32	13	45	2233.126
#35	MTA1	31	3	34	79.627
#36	ELF1	31	8	39	1432.062
#37	NFIL3	31	17	48	1153.039
#38	UHRF1	31	9	40	1021.628
#39	FOSL1	31	4	35	549.854
#40	ETV1	30	2	32	45.141
#41	ELF4	30	11	41	680.371
#42	LCOR	29	9	38	4004.136
#43	RUNX3	29	12	41	1769.473
#44	ZBTB38	29	16	45	2906.339
#45	GTF2H4	29	6	35	674.254
#46	TRIM22	28	17	45	2358.405
#47	TFDP2	28	15	43	1315.609
#48	CBFB	28	10	38	907.508
#49	ZFP36L2	27	17	44	2294.957
#50	ATF5	27	17	44	2642.494
#51	NFKB2	27	11	38	899.606
#52	PLSCR1	26	13	39	3319.174
#53	MEF2D	26	19	45	2457.155
#54	SPIB	26	14	40	734.73
#55	ZNF140	26	12	38	1037.697
#56	ETV6	26	13	39	1054.547
#57	NFYC	25	6	31	807.508
#58	MEF2C	25	24	49	2635.431
#59	ERF	25	4	29	342.081
#60	FOXP1	24	13	37	1607.739
#61	C5orf41	24	17	41	1473.276
#62	PBX2	24	7	31	114.295
#63	STAT3	24	12	36	802.882
#64	ZNF85	24	8	32	318.236
#65	PITX1	23	11	34	651.553
#66	BATF	23	13	36	1245.057
#67	ZNF217	23	10	33	529.362
#68	VDR	23	17	40	1922.383
#69	SUPT4H1	23	8	31	1382.979
#70	RB1	23	12	35	4013.688
#71	ZNF277	23	13	36	1337.553
#72	CITED2	23	13	36	1994.192
#73	EPAS1	22	2	24	508.893
#74	HIRA	22	7	29	720.727
#75	ZEB2	22	13	35	1372.458
#76	TSC22D1	22	17	39	3525.672
#77	TRIM25	22	8	30	966.759
#78	LASS2	22	7	29	1243.094
#79	HIF1A	21	13	34	1489.663
#80	KLF9	21	18	39	1467.901
#81	TCF4	21	21	42	2403.283
#82	SOX4	21	14	35	2277.821
#83	EHF	21	11	32	1684.377
#84	IRF9	21	12	33	1045.341
#85	CEBPD	21	14	35	1130.666
#86	ZNF91	20	8	28	789.781
#87	RORA	20	7	27	508.609
#88	CNOT7	20	11	31	1861.267
#89	RFXAP	20	17	37	2172.673
#90	NFIX	20	2	22	35.394
#91	NPAT	20	18	38	2764.581
#92	PRDM1	20	17	37	1320.406
#93	SCMH1	20	11	31	1479.028
#94	DDIT3	20	9	29	1109.449
#95	PA2G4	20	12	32	1547.417
#96	FOXJ3	20	11	31	544.38
#97	RUNX1	20	18	38	3150.005
#98	LASS6	19	17	36	1460.215
#99	ETV4	19	10	29	412.299
#100	CSRNP1	19	13	32	1845.695
#101	ZNF287	19	7	26	593.477
#102	VAV1	19	12	31	1374.928
#103	RBPJ	19	10	29	615.199
#104	ZNF496	19	17	36	2141.666
#105	FOSL2	19	10	29	339.28
#106	ZNF207	19	15	34	1051.873
#107	HOXA3	19	8	27	807.895
#108	E2F3	19	14	33	1575.44
#109	HCLS1	19	7	26	878.888
#110	SP1	18	10	28	572.219
#111	KLF10	18	12	30	1711.237
#112	NFYA	18	16	34	1891.889
#113	TAF12	18	10	28	793.97
#114	ZNF323	18	5	23	149.079
#115	CBFA2T3	18	23	41	2103.178
#116	TARDBP	18	17	35	751.547
#117	NOLC1	18	9	27	485.414
#118	TADA3	18	13	31	1144.922
#119	NR2F6	18	11	29	1266.688
#120	GATA3	18	8	26	266.385
#121	RXRA	17	10	27	1387.941
#122	SOX6	17	13	30	764.535
#123	ZNF281	17	11	28	974.309
#124	JUN	17	13	30	719.769
#125	CSRNP3	17	15	32	954.73
#126	ZFP90	17	18	35	1610.612
#127	ATF2	17	8	25	222.338
#128	FOXM1	17	15	32	1842.327
#129	RBCK1	17	11	28	1303.735
#130	TSHZ3	17	5	22	1330.211
#131	NFKB1	17	18	35	1501.577
#132	ZNF45	17	17	34	1350.821
#133	CREM	17	16	33	1018.065
#134	SATB2	17	21	38	2432.593
#135	ZNF138	17	11	28	1774.241
#136	PKNOX1	17	14	31	2044.58
#137	CLOCK	17	14	31	1084.927
#138	WT1	16	10	26	532.765
#139	ZBTB25	16	11	27	767.764
#140	RERE	16	14	30	1170.828
#141	KLF16	16	11	27	1576.975
#142	PPARA	16	10	26	1455.233
#143	ZNF367	16	14	30	1223.31
#144	SOX11	16	11	27	1516.445
#145	GTF2H2	16	13	29	966.62
#146	GLIS2	16	14	30	1242.346
#147	ZNF175	16	10	26	1151.233
#148	NKX3-1	16	10	26	2145.692
#149	FOXK2	16	13	29	1393.475
#150	IRX3	16	3	19	439.035
#151	NOTCH1	16	12	28	674.739
#152	MSL3	16	16	32	1614.429
#153	GLIS3	15	6	21	2020.158
#154	SATB1	15	20	35	2072.098
#155	PRRX2	15	3	18	125.404
#156	ZNF445	15	7	22	1682.362
#157	ZFP36L1	15	17	32	1630.134
#158	DMBX1	15	2	17	42.418
#159	ETS2	15	24	39	4107.776
#160	TFAM	15	8	23	586.789
#161	PRDM2	15	17	32	1574.772
#162	ZXDC	15	16	31	2676.7
#163	FOXP2	15	17	32	1210.555
#164	BHLHE41	15	6	21	872.31
#165	XBP1	15	20	35	1419.758
#166	ZBTB17	15	11	26	932.897
#167	ATF3	15	18	33	788.747
#168	STAT6	15	19	34	945.078
#169	ETV5	15	16	31	946.358
#170	HSF1	15	14	29	324.394
#171	CREBBP	15	9	24	1101.273
#172	ENO1	15	7	22	320.725
#173	SMAD6	15	15	30	1694.135
#174	RCAN1	15	17	32	1209.699
#175	IRF7	15	17	32	1475.158
#176	NFX1	15	14	29	1539.261
#177	NR4A2	15	1	16	35.507
#178	ZSCAN2	15	12	27	609.615
#179	NR2F1	14	12	26	640.643
#180	BACH2	14	19	33	914.181
#181	E2F1	14	17	31	735.065
#182	ZNF628	14	16	30	1431.641
#183	SREBF1	14	16	30	1735.211
#184	ZNF174	14	10	24	1312.226
#185	YY1	14	14	28	962.743
#186	ZNF83	14	12	26	1321.925
#187	FOXN3	14	14	28	1558.335
#188	GATAD2B	14	17	31	855.154
#189	CREBL2	14	17	31	1070.69
#190	SMAD2	14	18	32	1212.272
#191	NFATC1	14	20	34	1051.293
#192	NFE2L1	14	14	28	904.724
#193	CREB3L2	14	24	38	1809.106
#194	TCFL5	14	15	29	1618.457
#195	KLF3	14	6	20	443.944
#196	ZKSCAN4	14	18	32	1894.655
#197	IRF1	14	21	35	904.006
#198	SOLH	14	10	24	639.719
#199	GATAD2A	13	12	25	622.073
#200	IKZF1	13	13	26	846.28
#201	HMG20B	13	12	25	873.243
#202	EGR2	13	12	25	456.238
#203	C1orf85	13	23	36	1877.274
#204	DBP	13	18	31	1909.52
#205	EGR1	13	19	32	1612.924
#206	KLF15	13	12	25	1245.246
#207	SREBF2	13	18	31	683.148
#208	TCF3	13	13	26	1963.177
#209	FUBP1	13	15	28	1523.917
#210	ZNF71	13	14	27	1973.936
#211	STAT5A	13	12	25	847.437
#212	IRF2	13	17	30	1152.047
#213	HOPX	13	8	21	452.252
#214	TAF4B	13	12	25	695.158
#215	SOX12	13	15	28	769.41
#216	MLLT10	13	16	29	1025.599
#217	GABPB1	13	19	32	1558.539
#218	TCF7	13	5	18	366.954
#219	STAT5B	13	20	33	1456.157
#220	KLF5	13	13	26	781.951
#221	TRERF1	12	19	31	1111.814
#222	ELK1	12	9	21	281.652
#223	ZNF193	12	12	24	1113.846
#224	MSC	12	8	20	687.835
#225	ZNF33A	12	12	24	1004.28
#226	FOXG1	12	4	16	562.923
#227	ZNF236	12	15	27	734.167
#228	KDM5B	12	22	34	1073.753
#229	TEAD1	12	13	25	814.995
#230	HMX2	12	11	23	545.414
#231	ZNF434	12	14	26	725.344
#232	RCOR1	12	16	28	1025.899
#233	TCF12	12	17	29	2758.846
#234	ARNTL2	12	15	27	549.393
#235	ZNF256	12	23	35	1978.67
#236	SP4	12	18	30	820.138
#237	IRF5	12	14	26	1008.82
#238	SUPT6H	12	9	21	611.982
#239	ZNF268	12	16	28	2774.181
#240	EGR3	12	9	21	615.361
#241	NR4A3	12	7	19	564.777
#242	ARNT	12	11	23	760.145
#243	CTBP1	12	15	27	1184.009
#244	TAF5	12	11	23	1239.556
#245	NR2C1	12	14	26	712.95
#246	SIN3A	12	12	24	1083.536
#247	ZNF202	12	11	23	550.267
#248	PITX2	12	14	26	1234.405
#249	TCF19	12	19	31	1487.291
#250	ZFP37	12	18	30	909.396
#251	ZNF70	11	16	27	807.486
#252	BLZF1	11	17	28	713.192
#253	CDKN2A	11	23	34	2829.336
#254	ELK3	11	20	31	986.902
#255	TFEC	11	17	28	1183.835
#256	ARID3A	11	17	28	1290.804
#257	ZNF93	11	9	20	126.148
#258	MAFK	11	11	22	537.738
#259	MBD1	11	15	26	1916.984
#260	PBX3	11	16	27	799.246
#261	SLC2A4RG	11	16	27	1465.41
#262	ONECUT2	11	8	19	378.196
#263	NCOR1	11	13	24	831.596
#264	C12orf28	11	17	28	1863.574
#265	DMRT2	11	2	13	108.883
#266	NFIC	11	14	25	432.441
#267	POU3F2	11	12	23	1290.812
#268	PGBD1	11	13	24	624.708
#269	CBFA2T2	11	16	27	783.273
#270	FOXO3	11	21	32	1647.824
#271	LHX8	11	4	15	318.42
#272	ZNF232	11	19	30	1807.494
#273	SIX1	11	27	38	1226.48
#274	ZNF397	11	19	30	2741.428
#275	HOXA7	11	21	32	1459.417
#276	MTA2	11	11	22	556.544
#277	TGIF1	11	16	27	652.673
#278	FOS	10	17	27	1156.693
#279	TFE3	10	14	24	1189.746
#280	MLL	10	20	30	1773.872
#281	KLF12	10	18	28	868.817
#282	E2F5	10	18	28	592.287
#283	MGA	10	22	32	1046.302
#284	AEBP1	10	28	38	1405.078
#285	HOXC4	10	17	27	912.311
#286	TAF13	10	12	22	532.015
#287	FOXN4	10	5	15	325.214
#288	CIR1	10	10	20	1066.918
#289	ZHX1	10	15	25	972.929
#290	STAT4	10	6	16	861.338
#291	ZSCAN16	10	17	27	1578.33
#292	CTNNB1	10	9	19	649.448
#293	TSHZ1	10	16	26	927.088
#294	IRX5	10	14	24	1401.75
#295	RUNX2	10	25	35	1953.716
#296	HOXA1	10	24	34	2478.446
#297	LEF1	10	25	35	1454.426
#298	RELA	10	14	24	1360.801
#299	HOXB7	10	24	34	3516.557
#300	TEF	10	12	22	1364.578
#301	LZTS1	10	20	30	2139.1
#302	PPARD	10	10	20	1044.822
#303	MAFF	10	21	31	1980.744
#304	ZKSCAN1	10	18	28	1062.957
#305	ZIC2	10	18	28	1993.335
#306	TCEAL1	10	21	31	978.725
#307	TSC22D3	10	21	31	1126.3
#308	ZNF274	10	19	29	1026.554
#309	RXRB	10	13	23	618.422
#310	NKX2-1	10	4	14	492.568
#311	ZSCAN18	10	20	30	2328.527
#312	CEBPE	10	4	14	757.886
#313	MXD1	10	20	30	1353.954
#314	SNAI2	9	9	18	730.708
#315	SOX9	9	13	22	1263.625
#316	SOX7	9	15	24	409.838
#317	GATA2	9	4	13	376.777
#318	SOX8	9	6	15	541.215
#319	GAS7	9	15	24	378.863
#320	MSRB2	9	18	27	1270.691
#321	SMAD3	9	23	32	1926.876
#322	NR3C1	9	20	29	773.558
#323	ZNF117	9	18	27	469.225
#324	ZNF169	9	17	26	1484.838
#325	PURA	9	15	24	1261.997
#326	LMO4	9	24	33	1362.177
#327	POU2F1	9	15	24	472.523
#328	MEIS3P1	9	5	14	546.159
#329	MITF	9	11	20	311.751
#330	HEY2	9	20	29	1737.813
#331	SCAND3	9	11	20	801.457
#332	IRF4	9	16	25	559.052
#333	GLI3	9	8	17	911.749
#334	HOXD4	9	4	13	288.489
#335	KLF11	9	20	29	1233.26
#336	PLAGL2	9	20	29	1639.226
#337	NR1D2	9	18	27	1016.868
#338	IKZF4	9	16	25	650.418
#339	GTF2IRD1	9	24	33	1667.681
#340	ZNF643	9	19	28	852.262
#341	TAF1B	8	11	19	586.978
#342	TCF7L2	8	20	28	1225.867
#343	TP63	8	17	25	827.639
#344	TP53	8	29	37	2009.55
#345	RELB	8	15	23	386.337
#346	IKZF3	8	22	30	1001.758
#347	SOX2	8	7	15	658.424
#348	ZFHX3	8	19	27	548.956
#349	NFIA	8	21	29	600.255
#350	FOXC1	8	14	22	1141.628
#351	PBX4	8	14	22	523.001
#352	HOXA2	8	26	34	2069.886
#353	ST18	8	7	15	337.35
#354	HOXA5	8	19	27	736.029
#355	SIX2	8	3	11	126.404
#356	AHCTF1	8	13	21	425.038
#357	PLAG1	8	19	27	1552.577
#358	KLF6	8	19	27	1129.457
#359	FOXO6	8	8	16	464.386
#360	C2orf3	8	17	25	852.528
#361	AFF4	8	11	19	456.36
#362	NR4A1	8	14	22	885.461
#363	ESR2	8	17	25	753.738
#364	STAT2	8	7	15	176.948
#365	SOX5	8	6	14	326.643
#366	TFDP1	8	13	21	493.121
#367	NFATC3	8	14	22	626.158
#368	DLX1	8	6	14	101.096
#369	PROX1	8	15	23	1295.497
#370	FOXH1	8	5	13	584.155
#371	RORC	8	4	12	970.866
#372	ZNF187	8	20	28	730.288
#373	HMGA2	8	7	15	389.908
#374	FOXR2	8	7	15	1002.898
#375	NR1H2	8	11	19	451.583
#376	LHX3	8	5	13	198.898
#377	ZFPM1	8	20	28	721.32
#378	CSRNP2	8	17	25	1175.877
#379	GABPA	8	18	26	740.455
#380	CSDA	8	34	42	3636.403
#381	BACH1	7	17	24	495.232
#382	ZNF75D	7	18	25	786.454
#383	HOXB6	7	12	19	1081.008
#384	T	7	4	11	218.309
#385	HOXB5	7	4	11	579.116
#386	NFE2	7	4	11	127.99
#387	ATF7	7	20	27	868.162
#388	PHTF1	7	24	31	1167.722
#389	KLF2	7	12	19	1030.69
#390	MEIS1	7	12	19	935.944
#391	HOXA4	7	13	20	683.024
#392	RUNX1T1	7	12	19	1378.875
#393	HMGA1	7	17	24	378.181
#394	CBL	7	17	24	1127.691
#395	SCML1	7	5	12	596.942
#396	DMRT1	7	6	13	457.729
#397	ESRRG	7	10	17	923.202
#398	ZNF197	7	18	25	879.298
#399	TFCP2	7	24	31	1121.971
#400	ZNF35	7	16	23	391.053
#401	MYC	7	6	13	394.009
#402	AHR	7	20	27	989.87
#403	FOXL1	7	15	22	491.773
#404	NFE2L2	6	18	24	511.606
#405	ZNF3	6	21	27	891.138
#406	HMBOX1	6	22	28	943.904
#407	HEY1	6	20	26	987.807
#408	ARNTL	6	20	26	1422.58
#409	ZHX3	6	15	21	714.046
#410	ZNF33B	6	17	23	552.101
#411	RARA	6	15	21	441.019
#412	ADNP2	6	14	20	554.72
#413	TFAP2A	6	7	13	551.221
#414	SIM1	6	7	13	539.016
#415	PHF1	6	16	22	868.365
#416	NFAT5	6	17	23	665.238
#417	PBX1	6	7	13	523.728
#418	ASCL1	6	7	13	877.907
#419	SRF	6	21	27	810.862
#420	ZXDA	6	11	17	535.174
#421	ARID4A	6	15	21	383.419
#422	CREB3L1	6	7	13	135.565
#423	KLF7	6	12	18	843.989
#424	SMAD1	6	27	33	752.84
#425	ZIC1	6	8	14	555.415
#426	PURB	6	17	23	583.114
#427	FOXJ2	6	15	21	465.052
#428	HES1	6	25	31	1413.637
#429	ZSCAN5A	6	17	23	327.499
#430	TULP4	6	22	28	1172.363
#431	ZSCAN12	5	19	24	596.941
#432	ZFP42	5	12	17	803.385
#433	NFIB	5	25	30	1181.409
#434	NFE2L3	5	25	30	444.653
#435	NR3C2	5	8	13	285.052
#436	HOXB2	5	6	11	223.158
#437	TGIF2	5	14	19	201.134
#438	MAFB	5	10	15	208.298
#439	WNT5A	5	23	28	649.095
#440	HOXA9	5	10	15	467.275
#441	JDP2	5	24	29	1088.816
#442	L3MBTL4	5	8	13	530.524
#443	SIX4	5	22	27	804.176
#444	ERG	5	5	10	34.496
#445	PCGF2	5	21	26	1095.332
#446	CREB5	5	22	27	1103.747
#447	PRRX1	5	6	11	282.771
#448	GTF2I	5	18	23	814.104
#449	CREB3L4	5	16	21	345.799
#450	GATAD1	5	17	22	554.686
#451	TEAD4	4	24	28	484.92
#452	FOXP4	4	9	13	288.013
#453	CUX2	4	22	26	415.075
#454	LHX2	4	8	12	435.469
#455	ALS2CR8	4	13	17	426.168
#456	SCML2	4	20	24	719.676
#457	DLX2	4	20	24	368.435
#458	HSF2	4	19	23	297.883
#459	NR2C2	4	18	22	866.964
#460	TWIST1	4	2	6	95.006
#461	NFATC4	4	22	26	364.583
#462	HHEX	4	23	27	1034.264
#463	FOXJ1	4	7	11	721.676
#464	TAF5L	4	18	22	323.148
#465	HES6	4	18	22	354.345
#466	SMAD4	4	18	22	517.009
#467	TEAD2	4	4	8	132.517
#468	ELK4	4	18	22	1030.378
#469	GCFC1	4	17	21	348.818
#470	TSC22D4	4	22	26	387.677
#471	HOXB3	4	23	27	545.638
#472	EGR4	4	12	16	227.05
#473	SMAD5	4	20	24	520.401
#474	TBX21	4	14	18	1381.843
#475	ATF6	3	16	19	235.581
#476	HOXA10	3	28	31	1355.417
#477	JUND	3	17	20	333.738
#478	FOXD1	3	18	21	163.463
#479	TRPS1	3	22	25	565.218
#480	MZF1	3	16	19	422.875
#481	PAX6	3	7	10	281.218
#482	ISL2	3	22	25	885.042
#483	ZNF18	3	20	23	615.176
#484	ZNF134	3	26	29	322.821
#485	SMAD9	3	26	29	827.255
#486	ZNF148	3	12	15	338.888
#487	MSX1	2	21	23	250.244
#488	SLC30A9	2	23	25	379.397
#489	ZNF215	2	23	25	256.158
#490	SP140	2	21	23	229.023
#491	TP73	2	23	25	399.117
#492	CREBZF	2	22	24	460.186
#493	MNX1	2	21	23	191.8
#494	POU4F1	2	21	23	319.417
#495	ZNF167	1	13	14	134.012
#496	ZNF165	1	23	24	89.303
#497	ZNF131	1	17	18	164.909
#498	ZFHX4	1	7	8	22.602
#499	HIC1	1	12	13	60.101
#500	SPEN	0	17	17	0