Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ETS1	54	2	56	882.562
#2	IKZF1	52	2	54	261.27
#3	BATF3	52	1	53	23.527
#4	NFE2L2	50	3	53	505.712
#5	GTF2H3	49	2	51	6689.147
#6	FOXP1	47	4	51	520.951
#7	CREBBP	46	5	51	983.646
#8	ZFP90	43	6	49	7593.316
#9	MSRB2	41	8	49	400.458
#10	ATF3	40	2	42	293.296
#11	ADNP	40	5	45	338.141
#12	EPAS1	39	6	45	678.246
#13	FOXN2	39	5	44	540.528
#14	ATF1	38	3	41	51.503
#15	NR2C2	38	3	41	785.263
#16	KLF12	36	4	40	353.528
#17	TCF7	36	9	45	1348.341
#18	TFDP1	36	12	48	2580.384
#19	NFAT5	35	9	44	2370.914
#20	ENO1	35	5	40	2475.667
#21	SOX6	34	2	36	329.177
#22	CTCF	33	10	43	4336.008
#23	CBL	33	9	42	514.257
#24	LCOR	33	10	43	2511.47
#25	RB1	32	11	43	1169.552
#26	FOXO1	32	11	43	4035.779
#27	SPEN	32	5	37	1031.522
#28	SOX15	30	2	32	897.577
#29	PROX1	29	5	34	361.456
#30	ZNF24	29	4	33	1989.029
#31	TCF12	29	8	37	1660.302
#32	UHRF1	28	5	33	1826.836
#33	SATB1	28	12	40	818.657
#34	YY1	28	13	41	765.856
#35	SP3	27	7	34	1966.167
#36	USF2	27	7	34	753.658
#37	BUD31	27	8	35	614.448
#38	FOXJ3	27	13	40	1324.519
#39	ISL2	27	7	34	2906.434
#40	ZRANB2	26	8	34	349.174
#41	SPDEF	26	3	29	139.38
#42	NR2C1	26	8	34	1273.903
#43	STAT4	26	12	38	2367.431
#44	TAF4	26	11	37	2038.627
#45	ESRRA	26	6	32	1667.179
#46	POU2F2	26	8	34	1411.042
#47	GLIS2	26	10	36	1485.234
#48	HNRNPAB	26	9	35	1031.219
#49	FOXO3	26	8	34	2067.334
#50	ETV5	26	3	29	727.45
#51	LASS2	25	17	42	6092.667
#52	RFXAP	25	7	32	439.338
#53	HMG20A	25	14	39	1449.6
#54	CNOT7	25	11	36	1394.967
#55	ZFP36L1	24	9	33	680.675
#56	ZNF33B	24	6	30	529.528
#57	GCFC1	24	13	37	1326.268
#58	SP4	23	10	33	408.026
#59	UBP1	23	11	34	1003.15
#60	NR3C1	23	6	29	449.6
#61	KLF3	23	12	35	563.62
#62	ATF5	23	9	32	4180.898
#63	HOXD8	23	9	32	1145.842
#64	BTAF1	23	13	36	1143.928
#65	TCFL5	23	12	35	3886.462
#66	MYNN	22	9	31	768.632
#67	ZBTB25	22	17	39	2573.365
#68	SMAD4	22	11	33	1038.19
#69	ZNF83	22	8	30	411.745
#70	LMO4	22	12	34	2492.499
#71	MGA	22	7	29	803.862
#72	STAT1	22	12	34	5970.047
#73	ATF2	21	12	33	817.142
#74	C5orf41	21	9	30	447.179
#75	RERE	21	10	31	768.261
#76	ZEB1	21	13	34	1133.792
#77	ZNF91	21	11	32	973.498
#78	IRX2	21	4	25	209.988
#79	FOXM1	21	6	27	197.453
#80	HDAC2	21	14	35	5777.427
#81	NFATC2	21	13	34	3578.31
#82	RFX5	20	8	28	5484.011
#83	NPAT	20	15	35	580.406
#84	MAF	20	10	30	1080.745
#85	GATA3	20	10	30	1203.076
#86	ZHX2	20	16	36	1240.39
#87	ELK3	20	13	33	1738.024
#88	TSHZ2	20	10	30	1634.302
#89	E2F6	19	8	27	210.617
#90	DMTF1	19	14	33	530.365
#91	TRIM22	19	10	29	1136.015
#92	NCOR1	19	12	31	363.375
#93	CBFB	19	10	29	1234.119
#94	HMGB1	19	11	30	1002.346
#95	SLC30A9	19	16	35	2636.851
#96	CREB1	19	12	31	427.595
#97	CREB3L2	19	10	29	837.597
#98	PHF5A	19	13	32	1248.609
#99	TFEB	19	18	37	1680.778
#100	HIF1A	19	15	34	1785.274
#101	GATAD2A	19	13	32	1081.136
#102	ZNF189	18	15	33	4456.492
#103	BACH2	18	16	34	5019.45
#104	TEAD2	18	5	23	1646.553
#105	RAX2	18	5	23	1514.928
#106	NR1H3	18	15	33	952.766
#107	BHLHE40	18	14	32	4491.606
#108	SIM2	18	10	28	772.894
#109	MEIS3P1	18	14	32	1230.173
#110	PAX6	18	15	33	5105.529
#111	RELA	18	13	31	4961.358
#112	KLF16	18	4	22	434.723
#113	PTTG1	18	13	31	1851.483
#114	CSRNP2	18	11	29	3868.166
#115	BCL3	17	16	33	2894.481
#116	MAX	17	15	32	962.324
#117	BCL11B	17	11	28	937.172
#118	LASS6	17	14	31	826.541
#119	NEUROD1	17	10	27	383.179
#120	ECSIT	17	11	28	505.159
#121	NR2F6	17	15	32	1815.374
#122	MBD1	17	11	28	3291.511
#123	CNOT8	17	11	28	378.703
#124	CTBP1	17	12	29	1805.632
#125	NFE2L1	17	7	24	162.909
#126	TAF5	17	19	36	2574.129
#127	RBCK1	17	10	27	3305.82
#128	TFAM	17	12	29	2020.524
#129	ZKSCAN1	17	16	33	3616.903
#130	BACH1	16	13	29	1512.26
#131	ELF2	16	11	27	1994.127
#132	ZNF131	16	14	30	1669.403
#133	ZNF445	16	12	28	1251.37
#134	NFXL1	16	12	28	2341.904
#135	ZNF277	16	9	25	2980.257
#136	SUPT4H1	16	11	27	1073.698
#137	AATF	16	9	25	3406.675
#138	GLI3	16	11	27	2204.129
#139	TSHZ1	16	15	31	1360.802
#140	ELK1	16	11	27	926.746
#141	PCGF2	15	11	26	907.487
#142	ZNF446	15	9	24	1766.703
#143	NFIL3	15	11	26	2245.698
#144	KLF10	15	20	35	1374.641
#145	ZNF92	15	10	25	1360.323
#146	TCF19	15	9	24	393.252
#147	ZBTB38	15	11	26	2827.082
#148	HSF1	15	12	27	1227.381
#149	NR3C2	15	9	24	836.96
#150	EGR3	15	9	24	988.224
#151	ZNF219	15	9	24	766.574
#152	CSDA	15	15	30	1026.452
#153	SLC26A3	15	12	27	1033.263
#154	BTG2	15	15	30	678.419
#155	MZF1	15	12	27	1163.085
#156	ZNF217	14	12	26	496.057
#157	ZNF274	14	11	25	399.463
#158	PLAGL2	14	13	27	3906.957
#159	HMBOX1	14	15	29	1125.781
#160	ZNF367	14	7	21	507.462
#161	ATF4	14	11	25	735.672
#162	SP1	14	15	29	2019.306
#163	E2F4	14	9	23	229.04
#164	NANOG	14	19	33	1820.015
#165	RARA	14	13	27	3664.88
#166	ZSCAN20	14	8	22	615.334
#167	MLLT10	14	11	25	228.195
#168	NFATC1	14	11	25	740.089
#169	E2F8	13	9	22	3308.488
#170	ZNF45	13	12	25	2015.388
#171	IRF8	13	12	25	6211.295
#172	RCOR2	13	9	22	468.852
#173	SMAD1	13	10	23	1463.686
#174	TCF15	13	4	17	58.577
#175	EVX1	13	5	18	486.854
#176	NFYB	13	10	23	474.135
#177	CREB3	13	12	25	578.265
#178	HR	13	11	24	661.853
#179	FLI1	13	13	26	3857.272
#180	PRRX1	13	8	21	4222.274
#181	CREBZF	13	11	24	318.382
#182	ZIC2	13	6	19	395.825
#183	NFIB	13	14	27	1169.875
#184	ZNF639	13	11	24	448.201
#185	ZNF268	13	14	27	837.452
#186	ZNF434	13	15	28	1942.476
#187	SNAPC2	12	3	15	691.378
#188	CDKN2A	12	15	27	3571.643
#189	ARNTL2	12	9	21	1206
#190	RXRA	12	14	26	933.754
#191	TAF7	12	17	29	2443.597
#192	MSX1	12	12	24	1027.683
#193	SPIB	12	13	25	1867.531
#194	STAT5A	12	9	21	1658.857
#195	YEATS4	12	10	22	3805.143
#196	MEF2A	12	12	24	633.213
#197	MEIS1	12	8	20	522.272
#198	LHX2	12	9	21	604.716
#199	DMRT1	12	12	24	2998.493
#200	AFF1	12	11	23	374.485
#201	DMRT2	12	9	21	423.479
#202	CEBPD	12	17	29	2841.985
#203	BCL6	12	11	23	961.156
#204	CEBPB	12	12	24	1210.122
#205	BRD8	12	14	26	8323.964
#206	PRDM2	11	13	24	787.225
#207	GABPA	11	15	26	697.192
#208	ZNF37A	11	12	23	900.672
#209	ZHX1	11	13	24	1596.894
#210	FOXN3	11	17	28	508.377
#211	RUNX3	11	14	25	1211.763
#212	KLF2	11	10	21	1844.107
#213	ZFP36L2	11	15	26	1397.432
#214	FOS	11	6	17	784.76
#215	ZSCAN18	11	14	25	1551.941
#216	SIN3A	11	14	25	1081.924
#217	CUX1	11	18	29	5418.228
#218	HOXA1	11	14	25	2310.328
#219	AHCTF1	11	13	24	815.241
#220	CTNNB1	11	10	21	747.461
#221	SNAPC4	10	12	22	814.267
#222	RCOR1	10	19	29	1166.788
#223	TCF3	10	11	21	2592.914
#224	HNRNPK	10	17	27	1067.396
#225	AEBP1	10	15	25	2754.814
#226	EBF1	10	9	19	2031.887
#227	ZNF281	10	14	24	1930.996
#228	E2F2	10	10	20	649.731
#229	EHF	10	8	18	300.606
#230	ZNF500	10	13	23	864.193
#231	TAF1B	10	11	21	783.896
#232	MAFB	10	16	26	2233.269
#233	CREM	10	15	25	1799.762
#234	E2F1	10	11	21	307.568
#235	MEIS2	10	13	23	2346.321
#236	RHOXF1	10	11	21	4431.545
#237	MYBL2	10	7	17	2134.921
#238	E2F7	9	13	22	1769.911
#239	ZNF193	9	17	26	1177.361
#240	HMG20B	9	13	22	3032.678
#241	RUNX2	9	19	28	3912.772
#242	SCAND2	9	9	18	170.975
#243	EOMES	9	16	25	1645.69
#244	IRF4	9	13	22	2117.987
#245	SREBF1	9	14	23	1812.85
#246	EGR2	9	9	18	738.308
#247	PHF1	9	16	25	5292.404
#248	STAT3	9	17	26	2839.247
#249	SNAPC5	9	12	21	1321.726
#250	RBPJ	9	16	25	995.42
#251	ARNTL	9	15	24	327.425
#252	TRIM28	9	12	21	841.661
#253	LEF1	9	16	25	908.103
#254	ZNF397	9	13	22	4285.719
#255	AFF4	9	11	20	1110.647
#256	BHLHE41	9	9	18	602.079
#257	PPARD	9	10	19	1823.834
#258	HEYL	9	7	16	939.869
#259	FOSB	9	7	16	694.378
#260	TSHZ3	9	9	18	163.829
#261	ZNF75D	9	20	29	6882.569
#262	TBP	9	15	24	995.367
#263	DDIT3	9	13	22	4079.415
#264	IRF2	9	14	23	665.053
#265	SP140	8	18	26	1915.128
#266	HMGA1	8	15	23	1130.925
#267	TGIF1	8	17	25	2773.277
#268	STRN3	8	19	27	1435.974
#269	CREBL2	8	16	24	2880.494
#270	TWIST1	8	15	23	8827.076
#271	SMAD2	8	13	21	1233.569
#272	STAT5B	8	11	19	1093.24
#273	FBXW7	8	14	22	517.8
#274	CNBP	8	16	24	859.827
#275	REL	8	16	24	2379.287
#276	HOXA10	8	11	19	1355.979
#277	TAF10	8	12	20	327.653
#278	PLSCR1	8	17	25	1213.602
#279	GABPB1	8	14	22	1832.302
#280	NFYC	8	15	23	1820.841
#281	TRERF1	8	16	24	1214.698
#282	ASCL2	8	7	15	358.729
#283	HOXA7	8	12	20	1075.045
#284	POU2F1	8	7	15	949.808
#285	ZNF3	8	19	27	2117.405
#286	TCF4	8	17	25	764.764
#287	HOPX	8	18	26	1131.468
#288	C2orf3	8	16	24	1303.129
#289	FUBP1	8	17	25	695.166
#290	ETV1	8	9	17	2077.664
#291	NR2F2	8	5	13	1549.734
#292	HCLS1	7	10	17	650.693
#293	PPARA	7	11	18	1209.553
#294	JUN	7	9	16	1569.517
#295	MAFF	7	16	23	1445.191
#296	MITF	7	14	21	1052.96
#297	RORA	7	18	25	1291.419
#298	PBX4	7	15	22	720.226
#299	ETS2	7	9	16	1011.094
#300	PURB	7	14	21	834.208
#301	KLF11	7	14	21	806.142
#302	MLL	7	14	21	724.657
#303	EGR1	7	8	15	546.429
#304	PURA	7	18	25	3321.072
#305	FOXP2	7	10	17	1324.411
#306	HIRA	7	15	22	794.255
#307	SMAD6	7	10	17	1725.3
#308	SLC2A4RG	7	12	19	379.956
#309	VDR	7	17	24	2108.982
#310	BATF	7	14	21	747.368
#311	HOXC9	7	7	14	8656.163
#312	ZNF138	7	18	25	724.713
#313	ZKSCAN5	7	11	18	333.946
#314	ZNF202	7	10	17	249.166
#315	THRB	7	13	20	359.433
#316	MAFG	6	13	19	1171.819
#317	FOXC1	6	18	24	887.178
#318	HEY1	6	14	20	1205.997
#319	HMGB2	6	12	18	454.632
#320	SOX4	6	16	22	1679.132
#321	TSC22D2	6	16	22	869.817
#322	ETV6	6	14	20	654.411
#323	GAS7	6	13	19	1787.814
#324	ZNF80	6	16	22	840.408
#325	SATB2	6	16	22	204.628
#326	SCAND1	6	12	18	391.649
#327	CBFA2T2	6	15	21	1300.318
#328	MYT1L	6	4	10	582.897
#329	TFEC	6	12	18	3165.67
#330	ZNF148	6	18	24	1149.482
#331	KDM5A	6	18	24	1833.774
#332	FOSL2	6	8	14	481.64
#333	PBX3	6	19	25	511.965
#334	HDAC1	6	16	22	993.15
#335	NFIC	6	15	21	6330.457
#336	MXD1	6	16	22	1076.836
#337	MNT	6	17	23	685.413
#338	C1orf85	6	15	21	577.372
#339	ZNF238	6	17	23	1036.56
#340	KLF7	6	15	21	2695.754
#341	PA2G4	6	10	16	962.081
#342	HOXA5	6	16	22	1831.637
#343	ARID4A	6	11	17	127.682
#344	TSC22D4	6	14	20	3235.352
#345	RFXANK	6	8	14	534.284
#346	ZKSCAN3	6	12	18	689.557
#347	TRPS1	6	13	19	2287.139
#348	MTF1	6	13	19	1648.616
#349	NR2E3	6	9	15	227.425
#350	RORC	6	12	18	1409.49
#351	BLZF1	6	13	19	890.769
#352	ZNF18	6	12	18	796.4
#353	JUNB	6	11	17	1269.047
#354	NR5A2	6	11	17	2921.169
#355	SOX11	5	9	14	546.487
#356	ZSCAN16	5	14	19	201.141
#357	CSRNP1	5	12	17	934.906
#358	PKNOX1	5	13	18	1075.926
#359	TGIF2	5	14	19	1214.196
#360	IKZF4	5	8	13	996.623
#361	IRF7	5	14	19	703.531
#362	ATF7	5	14	19	945.888
#363	SIX3	5	7	12	942.892
#364	NFX1	5	17	22	4969.261
#365	SIX1	5	11	16	832.579
#366	FOXC2	5	7	12	246.349
#367	GATAD1	5	12	17	627.807
#368	TSC22D1	5	12	17	2081.196
#369	TRIM25	5	9	14	645.3
#370	HOXB3	5	20	25	1641.168
#371	ZNF236	5	12	17	219.502
#372	ZGPAT	5	18	23	1884.346
#373	ZNF117	5	14	19	1047.048
#374	ZNF174	5	17	22	987.255
#375	ZNF256	5	14	19	974.782
#376	SCML1	5	12	17	300.778
#377	ZBTB17	5	13	18	1594.64
#378	ZIC1	5	10	15	813.849
#379	ZNF394	5	16	21	648
#380	DBP	5	13	18	1173.756
#381	MLX	5	11	16	369.317
#382	ELF1	5	15	20	983.94
#383	ELF4	5	15	20	451.461
#384	ZFPM1	5	13	18	1615.979
#385	TCEAL1	5	13	18	595.836
#386	ONECUT2	5	14	19	338.872
#387	ZNF133	5	12	17	1363.894
#388	CCRN4L	5	12	17	402.973
#389	RNF4	5	13	18	1910.405
#390	EDF1	5	10	15	263.196
#391	KLF9	4	13	17	448
#392	NFYA	4	16	20	3066.562
#393	PPARG	4	7	11	160.699
#394	MTA1	4	15	19	504.801
#395	SMAD3	4	16	20	1503.734
#396	TFDP2	4	12	16	3626.012
#397	PBX1	4	8	12	395.804
#398	NFATC3	4	14	18	186.587
#399	ETV7	4	13	17	936.569
#400	HOXB7	4	18	22	670.855
#401	ZNF167	4	16	20	2069.571
#402	ZNF207	4	22	26	1014.325
#403	FOXK1	4	15	19	1294.571
#404	TFE3	4	12	16	859.437
#405	JUND	4	13	17	1262.272
#406	NOTCH1	4	12	16	653.21
#407	FOXO6	4	11	15	1917.517
#408	HOXB2	4	16	20	2074.826
#409	TARDBP	4	15	19	191.6
#410	TFAP2E	4	13	17	1275.238
#411	MYCN	4	10	14	1040.693
#412	SALL2	4	9	13	876.815
#413	PHTF1	4	15	19	3246.399
#414	SOX2	4	14	18	1135.82
#415	ZKSCAN4	4	13	17	333.949
#416	FOXR2	4	15	19	2735.363
#417	HES1	4	17	21	625.806
#418	MSL3	4	11	15	164.923
#419	CEBPA	4	12	16	1356.298
#420	CREB5	3	14	17	932.933
#421	IRX3	3	9	12	345.05
#422	PRDM1	3	17	20	410.774
#423	MAFK	3	13	16	3403.636
#424	MYC	3	15	18	712.346
#425	TAF4B	3	10	13	911.331
#426	TP63	3	16	19	238.911
#427	STAT2	3	16	19	3020.341
#428	ZEB2	3	10	13	360.637
#429	ADNP2	3	12	15	993.103
#430	ZNF85	3	14	17	291.009
#431	HINFP	3	13	16	669.956
#432	NFE2L3	3	14	17	147.725
#433	RCAN1	3	8	11	943.117
#434	ZSCAN21	3	15	18	1110.798
#435	TCF25	3	11	14	983.901
#436	NOLC1	3	13	16	226.857
#437	FOXA2	3	7	10	731.462
#438	MESP1	3	12	15	206.557
#439	ISL1	3	8	11	453.039
#440	IRF1	3	11	14	460.284
#441	STAT6	3	15	18	270.206
#442	IKZF3	3	16	19	1271.773
#443	HSF5	3	19	22	270.939
#444	FOXD1	3	16	19	568.248
#445	POU6F1	3	13	16	166.404
#446	SCML2	3	14	17	1738.9
#447	NR1D2	3	12	15	1355.266
#448	TP53	3	14	17	694.822
#449	SNAI2	3	12	15	129.015
#450	CITED2	3	19	22	2112.7
#451	ZNF213	3	10	13	137.896
#452	CEBPE	3	13	16	2059.899
#453	MEF2D	3	9	12	629.178
#454	LASS5	3	11	14	2210.78
#455	PLAG1	3	10	13	956.762
#456	CUX2	3	9	12	1182.576
#457	NR4A2	3	13	16	311.481
#458	HES6	2	9	11	348.01
#459	TULP4	2	13	15	974.511
#460	DLX6	2	8	10	185.07
#461	SMAD5	2	12	14	238.415
#462	IRF9	2	12	14	1451.05
#463	GTF2IRD1	2	17	19	286.783
#464	ZFHX3	2	7	9	3125.121
#465	HOXA2	2	16	18	401.342
#466	ARNT	2	16	18	602.883
#467	ZNF70	2	11	13	236.954
#468	ZXDC	2	11	13	1039.292
#469	AHR	2	15	17	548.998
#470	MEOX1	2	16	18	443.994
#471	YBX1	2	17	19	211.612
#472	ASCL1	2	14	16	836.278
#473	HOXA9	2	15	17	1006.476
#474	DLX4	2	14	16	181.197
#475	IRF5	2	15	17	520.927
#476	ZNF643	2	6	8	206.608
#477	E2F3	2	15	17	198.662
#478	HLF	2	7	9	729.018
#479	RUNX1	1	18	19	213.488
#480	CLOCK	1	11	12	52.643
#481	KDM5B	1	14	15	80.386
#482	TCF7L2	1	20	21	2314.267
#483	HOXA3	1	13	14	129.171
#484	FOXK2	1	13	14	152.619
#485	ZNF496	1	19	20	721.032
#486	HSF2	1	12	13	106.007
#487	HEY2	1	9	10	40.055
#488	KLF6	1	15	16	265.846
#489	SHOX	1	11	12	432.643
#490	WNT5A	1	14	15	47.044
#491	ZNF232	1	12	13	177.163
#492	XBP1	0	14	14	0
#493	ISX	0	9	9	0
#494	ZC3H8	0	9	9	0
#495	TSC22D3	0	12	12	0
#496	POU2F3	0	10	10	0
#497	KLF4	0	12	12	0
#498	ZNF81	0	12	12	0
#499	MEF2C	0	20	20	0
#500	UBN1	0	11	11	0