Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	FOXF1	73	1	74	129.572
#2	C5orf41	66	4	70	276.692
#3	NR3C1	57	2	59	30.069
#4	PEG3	51	1	52	1084.193
#5	ZBTB48	44	5	49	710.106
#6	CBL	41	2	43	753.52
#7	ZNF135	41	6	47	1609.011
#8	ZNF444	41	2	43	303.676
#9	HOXA4	41	2	43	2560.298
#10	YEATS4	39	2	41	246.62
#11	ZFHX3	39	6	45	319.286
#12	TCF21	39	12	51	1885.532
#13	NFE2L3	39	13	52	1447.004
#14	SP3	39	6	45	452.172
#15	ZSCAN18	38	9	47	882.576
#16	STAT4	37	8	45	1265.805
#17	MITF	37	10	47	2636.29
#18	CITED2	36	7	43	485.396
#19	MEIS3P1	34	6	40	400.491
#20	MEIS1	34	9	43	318.893
#21	C11orf9	34	5	39	2383.758
#22	ADNP	33	8	41	2854.061
#23	AFF4	33	4	37	1078.593
#24	CBFB	33	10	43	567.464
#25	SOLH	32	5	37	1983.929
#26	HMGA1	32	14	46	4392.231
#27	NFIC	32	11	43	1312.839
#28	ZHX1	32	3	35	121.788
#29	HOXD13	31	10	41	3347.304
#30	SCRT1	31	7	38	1296.338
#31	NFATC3	31	9	40	2681.427
#32	HAND2	31	6	37	259.428
#33	RFX1	31	10	41	2653.124
#34	ZFHX4	31	8	39	2082.837
#35	ATF1	30	3	33	145.807
#36	FOXP1	30	9	39	640.866
#37	ELF3	30	11	41	1960.733
#38	PPARG	29	9	38	959.825
#39	HOXD3	29	9	38	3697.726
#40	TSC22D4	29	5	34	2439.673
#41	TGIF1	29	8	37	1616.746
#42	CUX1	29	13	42	7143.772
#43	TSC22D1	28	0	28	0
#44	TFDP1	28	10	38	787.899
#45	ESRRA	28	9	37	1776.585
#46	MSL3	27	11	38	700.627
#47	TCF25	27	6	33	876.799
#48	PITX2	27	8	35	787.131
#49	MSC	27	10	37	1196.265
#50	PCGF6	27	11	38	2540.635
#51	NFIA	26	9	35	555.933
#52	KLF4	26	14	40	2351.947
#53	SP140	26	5	31	759.195
#54	FOXA3	26	19	45	3155.907
#55	HCLS1	26	4	30	1257.802
#56	NOLC1	26	8	34	752.455
#57	ZNF3	26	11	37	4638.677
#58	NFE2L1	25	15	40	1633.734
#59	NFYB	25	5	30	816.525
#60	NR1H2	25	8	33	1068.811
#61	TSHZ1	25	9	34	745.192
#62	NFX1	25	7	32	1133.333
#63	TCF4	24	12	36	971.796
#64	ZHX3	24	7	31	547.219
#65	TCF3	24	8	32	744.697
#66	SOX9	24	11	35	969.767
#67	E2F6	24	12	36	5819.118
#68	MLLT10	24	5	29	2251.313
#69	HOXA2	23	8	31	1141.756
#70	GTF2IRD1	23	11	34	972.326
#71	IRF3	23	10	33	604.416
#72	HDAC2	23	12	35	1306.592
#73	MEF2C	23	15	38	4250.079
#74	PFDN1	23	12	35	1276.211
#75	HSF2	23	8	31	1241.333
#76	RFXANK	23	9	32	577.046
#77	SALL2	23	10	33	1489.826
#78	ZNF75D	23	15	38	1664.879
#79	KLF5	22	13	35	936.461
#80	NFXL1	22	8	30	1049.943
#81	RNF4	22	11	33	1821.298
#82	E4F1	22	15	37	2582.236
#83	MECOM	22	13	35	2746.413
#84	HINFP	22	8	30	998.572
#85	NPAS1	22	14	36	4680.116
#86	TFDP2	22	14	36	1167.633
#87	HEY1	22	12	34	3249.143
#88	RUNX1	22	11	33	3206.438
#89	MAFF	22	7	29	1129.316
#90	RAX2	21	7	28	830.612
#91	OVOL1	21	9	30	409.895
#92	ETV4	21	11	32	1131.07
#93	RORA	21	12	33	1582.908
#94	CNBP	21	6	27	173.961
#95	EPAS1	21	11	32	1531.305
#96	ZEB2	21	13	34	829.844
#97	HOXA10	21	11	32	1574.274
#98	RUNX1T1	21	8	29	100.385
#99	HLF	20	9	29	573.302
#100	CNOT7	20	10	30	578.274
#101	BLZF1	20	3	23	537.898
#102	FOXA2	20	13	33	646.67
#103	POU6F1	20	13	33	2713.827
#104	SREBF1	20	13	33	2522.438
#105	ZNF274	20	3	23	82.705
#106	RELA	20	4	24	108.458
#107	CDX2	20	10	30	2115.603
#108	ISL1	20	14	34	2774.249
#109	ELK1	19	10	29	555.41
#110	IRF6	19	13	32	1160.495
#111	NFYC	19	13	32	775.695
#112	TCF20	19	14	33	1490.414
#113	XBP1	19	15	34	1952.222
#114	MSX1	19	17	36	3424.104
#115	LZTS1	19	14	33	1425.696
#116	BARX1	18	9	27	442.637
#117	CBFA2T2	18	13	31	2075.764
#118	CSRNP2	18	18	36	3762.565
#119	HNF4G	18	13	31	2312.634
#120	SOX13	18	15	33	3363.639
#121	HOXA9	18	15	33	3411.55
#122	TEAD4	18	11	29	716.195
#123	TAF4	18	9	27	1354.964
#124	HIC1	18	13	31	1959.708
#125	STAT2	18	12	30	3573.511
#126	PBX1	18	15	33	1356.359
#127	ERF	18	12	30	2360.436
#128	ZSCAN2	18	14	32	1566.568
#129	ENO1	18	13	31	3656.573
#130	KLF12	17	11	28	2469.173
#131	CSRNP3	17	13	30	3586.272
#132	TFAP2A	17	14	31	5062.076
#133	ZNF18	17	13	30	876.253
#134	TSC22D3	17	18	35	1487.785
#135	VAV1	17	6	23	474.868
#136	TCF7L1	17	11	28	4768.948
#137	PBX3	17	10	27	620.798
#138	NFIX	17	12	29	1766.476
#139	KLF2	17	18	35	2259.767
#140	GATAD1	17	12	29	2114.923
#141	SOX4	17	17	34	2396.158
#142	ZFP36L2	17	11	28	1417.231
#143	LASS6	17	18	35	4579.067
#144	FOXQ1	17	16	33	1646.402
#145	ZFP90	16	13	29	1192.008
#146	IRF7	16	14	30	2237.6
#147	ZNF69	16	2	18	1279.09
#148	PHF1	16	14	30	3855.231
#149	HNF1B	16	14	30	1345.956
#150	RORC	16	9	25	2734.036
#151	ZNF263	16	6	22	300.937
#152	NR2F2	16	16	32	5492.613
#153	PRRX1	16	13	29	2349.874
#154	PCGF2	16	14	30	1377.662
#155	PROX1	16	14	30	1552.287
#156	SOX18	16	13	29	2589.511
#157	ZNF187	16	7	23	394.679
#158	RCAN1	16	12	28	1724.996
#159	FOXE1	16	7	23	758.386
#160	TAF7	15	10	25	322.769
#161	ATF6	15	11	26	6173.279
#162	NKX3-2	15	16	31	1126.59
#163	YY1	15	12	27	685.65
#164	USF1	15	17	32	1574.488
#165	ZNF500	15	15	30	2831.461
#166	TAF6	15	7	22	723.47
#167	TSHZ3	15	12	27	2087.519
#168	CTNNB1	15	8	23	740.964
#169	EBF1	15	9	24	610.666
#170	ETV6	15	17	32	5282.335
#171	CEBPB	15	15	30	2054.243
#172	SATB2	15	24	39	2367.745
#173	ASCL2	15	16	31	3291.311
#174	CCRN4L	15	13	28	1457.277
#175	AFF1	15	14	29	752.6
#176	NFE2L2	14	18	32	2044.883
#177	RUNX3	14	14	28	4285.068
#178	SCMH1	14	9	23	1331.27
#179	GATAD2B	14	6	20	159.374
#180	AEBP1	14	14	28	920.269
#181	MNT	14	15	29	1022.552
#182	SNAPC4	14	8	22	1554.935
#183	PLSCR1	14	12	26	402.037
#184	YBX1	14	18	32	1551.802
#185	ZNF133	14	16	30	1675.805
#186	ZSCAN16	14	16	30	2284.941
#187	NR1I2	14	6	20	757.097
#188	IRX3	14	10	24	1322.105
#189	HES6	14	20	34	3700.915
#190	ATF3	14	5	19	211.614
#191	PTTG1	14	15	29	3807.431
#192	HES1	13	10	23	1358.278
#193	TSC22D2	13	9	22	325.352
#194	PRDM1	13	15	28	1000.356
#195	HOXA13	13	11	24	277.106
#196	LCOR	13	9	22	621.28
#197	FOXA1	13	12	25	863.257
#198	FOS	13	6	19	449.612
#199	ZNF134	13	9	22	469.732
#200	THRA	13	14	27	1071.648
#201	JUN	12	11	23	1983.525
#202	AHCTF1	12	14	26	1748.182
#203	TCEAL1	12	19	31	655.647
#204	MSX2	12	13	25	620.232
#205	PURA	12	9	21	845.269
#206	TEAD2	12	15	27	1532.599
#207	NME2	12	11	23	2457.742
#208	NR1H3	12	16	28	574.424
#209	IRF4	12	12	24	2500.008
#210	USF2	12	13	25	1439.24
#211	FOXO4	12	14	26	1329.416
#212	VDR	12	13	25	2367.596
#213	ZNF140	12	15	27	2361.952
#214	HMBOX1	12	15	27	687.379
#215	CIR1	12	9	21	3399.294
#216	BATF	12	20	32	3692.476
#217	MAF	12	20	32	1179.341
#218	SP4	12	16	28	2572.354
#219	FOXJ2	12	13	25	1252.909
#220	ASCL1	12	16	28	1347.139
#221	RBPJL	12	15	27	3193.668
#222	HOXA5	12	13	25	742.139
#223	SLC30A9	12	17	29	913.473
#224	SOX2	12	22	34	1867.73
#225	IRX6	12	6	18	1303.991
#226	DMTF1	12	8	20	656.926
#227	TCFL5	12	14	26	2895.416
#228	NFKB2	12	10	22	629.117
#229	PLAGL2	12	10	22	629.98
#230	ZFP42	12	12	24	445.76
#231	SMAD6	12	13	25	889.831
#232	ESRRG	11	14	25	1379.111
#233	MLXIPL	11	15	26	2394.03
#234	CEBPA	11	20	31	3712.017
#235	NR4A2	11	10	21	1036.627
#236	NR2F1	11	15	26	1301.51
#237	HOXB2	11	14	25	1175.221
#238	HOXC4	11	20	31	2839.596
#239	ETS1	11	14	25	921.575
#240	MZF1	11	12	23	199.841
#241	ZRANB2	11	9	20	501.355
#242	SCAND1	11	15	26	1366.867
#243	CSDA	11	13	24	1569.868
#244	GAS7	11	12	23	510.332
#245	LASS2	11	11	22	430.052
#246	TCF7L2	11	16	27	2563.317
#247	ZNF219	11	12	23	998.494
#248	NFIL3	11	12	23	1026.244
#249	HIF1A	11	14	25	1162.64
#250	AHR	11	5	16	264.227
#251	FLI1	11	7	18	1024.624
#252	POU5F1	11	17	28	1707.32
#253	CREB5	11	9	20	1736.154
#254	ZNF639	11	7	18	271.185
#255	ETV7	11	18	29	2072.497
#256	ZBTB17	11	12	23	701.554
#257	MMP14	11	20	31	2978.699
#258	CREB3	11	10	21	2050.112
#259	CREM	11	17	28	2027.891
#260	CREB1	10	6	16	1367.054
#261	STAT5B	10	12	22	539.065
#262	RCOR2	10	18	28	1039.85
#263	SIX5	10	16	26	1002.543
#264	PHTF1	10	12	22	655.285
#265	E2F7	10	11	21	529.962
#266	RARB	10	11	21	141.411
#267	CREBZF	10	10	20	171.992
#268	ZNF148	10	10	20	270.211
#269	FOSB	10	11	21	1460.774
#270	EOMES	10	14	24	826.426
#271	LZTR1	10	11	21	2273.691
#272	ETV5	10	16	26	871.889
#273	REXO4	10	10	20	1309.012
#274	GABPA	10	12	22	884.203
#275	MKX	10	14	24	968.946
#276	CNOT8	10	12	22	1272.425
#277	MYC	10	19	29	2342.537
#278	FUBP1	10	15	25	974.733
#279	LEF1	9	24	33	2512.474
#280	SOX21	9	11	20	2009.192
#281	ZNF175	9	14	23	2106.5
#282	NOTCH1	9	14	23	992.377
#283	GCM1	9	12	21	1295.348
#284	RERE	9	12	21	570.983
#285	HOPX	9	16	25	1556.995
#286	ELF2	9	14	23	1892.405
#287	ZNF268	9	9	18	596.246
#288	ZNF33B	9	16	25	833.867
#289	TRIM25	9	9	18	508.277
#290	SMAD3	9	22	31	1076.741
#291	STAT5A	9	18	27	2071.207
#292	REL	9	15	24	2386.712
#293	NR5A2	9	16	25	3775.05
#294	FOXM1	9	15	24	413.926
#295	HOXC8	9	11	20	1104.922
#296	DBP	9	16	25	956.626
#297	TGIF2	9	14	23	1070.736
#298	KLF11	9	20	29	2191.822
#299	DRAP1	9	9	18	683.785
#300	E2F2	9	15	24	358.957
#301	CDKN2A	8	15	23	1030.942
#302	FOXD2	8	20	28	664.603
#303	FBXW7	8	12	20	594.471
#304	SMAD9	8	12	20	617.271
#305	ZFPM1	8	16	24	317.812
#306	TULP4	8	18	26	2178.149
#307	STAT3	8	16	24	834.607
#308	ELK4	8	15	23	1470.058
#309	ZNF394	8	3	11	41.866
#310	BATF3	8	11	19	1418.376
#311	PRRX2	8	16	24	2328.537
#312	SCML1	8	16	24	786.673
#313	BACH2	8	13	21	975.498
#314	ATF4	8	14	22	1021.781
#315	FOXK1	8	14	22	1271.391
#316	MEOX1	8	11	19	561.938
#317	TWIST1	8	16	24	487.943
#318	KLF6	8	10	18	706.094
#319	TFAM	8	15	23	555.559
#320	HHEX	8	17	25	1785.569
#321	ZNF217	8	17	25	1232.149
#322	RXRB	8	13	21	779.724
#323	HOXB5	8	14	22	1719.618
#324	TP53	8	13	21	856.493
#325	EHF	7	10	17	444.561
#326	IRF8	7	14	21	1016.122
#327	HOXC9	7	10	17	487.833
#328	MEOX2	7	17	24	1565.548
#329	JUNB	7	17	24	1109.561
#330	CTBP1	7	10	17	152.477
#331	ZNF323	7	15	22	2028.23
#332	MLX	7	12	19	1182.801
#333	HOXB7	7	23	30	1761.543
#334	GATA6	7	17	24	1434.166
#335	GRHL2	7	13	20	407.517
#336	SPI1	7	8	15	1081.659
#337	TFCP2	7	14	21	802.313
#338	BHLHE41	7	15	22	802.204
#339	ELF1	7	19	26	1607.062
#340	UHRF1	7	10	17	644.663
#341	MXD1	7	19	26	1307.203
#342	HOXC13	7	14	21	940.778
#343	GTF2H3	7	9	16	189.871
#344	TEAD3	7	13	20	330.634
#345	PA2G4	7	15	22	422.76
#346	KLF9	7	16	23	431.137
#347	IRF1	7	16	23	1055.817
#348	STRN3	6	15	21	806.667
#349	BCL6	6	21	27	1228.469
#350	SNAI2	6	14	20	565.229
#351	HOXD1	6	16	22	3580.498
#352	FOXF2	6	9	15	258.261
#353	HNRNPAB	6	20	26	1504.031
#354	NR2F6	6	15	21	715.584
#355	HEY2	6	9	15	214.746
#356	NFATC1	6	19	25	2734.337
#357	TRIM29	6	18	24	453.538
#358	DDIT3	6	19	25	1152.002
#359	HNRNPK	6	16	22	683.45
#360	RXRA	6	18	24	1359.84
#361	POU2F1	6	13	19	292.762
#362	MTA3	6	12	18	533.234
#363	NR3C2	6	20	26	1151.04
#364	RARA	6	15	21	1051.314
#365	EGR1	6	13	19	267.295
#366	HOXB13	6	15	21	887.526
#367	ZNF483	6	6	12	1175.15
#368	ZGPAT	6	18	24	1318.112
#369	NKX6-2	6	14	20	893.562
#370	E2F5	6	16	22	442.241
#371	TRIM22	6	16	22	438.625
#372	NFE2	6	15	21	1533.193
#373	ATF5	5	17	22	749.934
#374	ZNF281	5	15	20	856.441
#375	KLF15	5	14	19	372.798
#376	TADA3	5	8	13	726.959
#377	ONECUT2	5	18	23	2339.936
#378	CEBPD	5	13	18	1402.255
#379	SPIB	5	15	20	840.822
#380	ZNF277	5	17	22	1347.53
#381	BUD31	5	14	19	994.134
#382	PLAG1	5	19	24	986.151
#383	GLIS3	5	16	21	3731.093
#384	ZNF83	5	19	24	630.512
#385	HOXB6	5	17	22	587.824
#386	TBX2	5	17	22	250.336
#387	RELB	5	14	19	556.153
#388	ZNF165	5	12	17	342.475
#389	C1orf85	5	15	20	409.152
#390	BCL11B	5	19	24	1571.142
#391	FOXD1	5	17	22	1572.13
#392	CSRNP1	4	16	20	392.993
#393	GATA4	4	19	23	440.434
#394	EGR3	4	9	13	951.88
#395	PBX4	4	15	19	905.781
#396	SMAD4	4	16	20	776.086
#397	NR2C1	4	18	22	598.539
#398	MAFB	4	13	17	1768.305
#399	MEIS2	4	14	18	439.355
#400	TAF4B	4	20	24	348.936
#401	FOXS1	4	13	17	478.88
#402	MTA1	4	16	20	268.021
#403	NKX3-1	4	15	19	241.398
#404	IKZF1	4	14	18	1079.985
#405	NR1H4	4	13	17	393.198
#406	SLC26A3	4	16	20	383.107
#407	TFCP2L1	4	15	19	732.165
#408	ZFP37	4	17	21	515.438
#409	TEF	4	19	23	660.917
#410	TRIM28	4	12	16	579.937
#411	LHX6	4	14	18	393.379
#412	BATF2	4	18	22	1551.353
#413	ZNF256	4	11	15	180.358
#414	MEF2D	4	17	21	578.58
#415	NFIB	4	14	18	708.165
#416	MYCN	4	11	15	485.61
#417	SMAD5	4	13	17	918.509
#418	TAF1B	4	12	16	932.861
#419	ZNF85	4	11	15	671.123
#420	ARNT2	4	16	20	643.972
#421	STAT1	4	15	19	1823.922
#422	ARID3A	4	15	19	316.068
#423	MYT1	4	15	19	863.202
#424	BHLHE40	4	10	14	228.307
#425	ELF4	3	15	18	1951.991
#426	RBCK1	3	20	23	427.298
#427	IRF9	3	15	18	496.725
#428	SOX15	3	15	18	415.627
#429	WNT5A	3	23	26	527.459
#430	ZHX2	3	16	19	352.279
#431	HOXA3	3	22	25	401.023
#432	ZFP36L1	3	17	20	308.248
#433	ELF5	3	16	19	1065.023
#434	MAFA	3	16	19	961.1
#435	VTN	3	9	12	679.742
#436	ZKSCAN1	3	10	13	176.725
#437	SOX30	3	7	10	108.54
#438	HEYL	3	18	21	325.556
#439	NPAS2	3	19	22	296.328
#440	RBPJ	3	9	12	415.798
#441	RUNX2	3	14	17	257.5
#442	SIM2	3	14	17	830.486
#443	ZNF232	3	19	22	360.614
#444	MESP1	3	16	19	406.502
#445	TBX3	3	18	21	873.643
#446	MYPOP	3	13	16	502.279
#447	IRX2	3	16	19	1722.718
#448	SPDEF	3	16	19	133.6
#449	HOXC6	3	13	16	207.332
#450	HAND1	3	6	9	78.309
#451	TBX10	3	6	9	239.785
#452	CREB3L2	3	15	18	166.235
#453	ZNF238	3	8	11	292.019
#454	FOSL1	3	17	20	267.049
#455	ZNF189	3	18	21	1183.2
#456	EGR2	3	16	19	644.791
#457	MSRB2	3	17	20	1373.029
#458	SCML2	3	13	16	437.811
#459	EDF1	2	24	26	3280.292
#460	ZIC2	2	17	19	127.375
#461	TCF12	2	15	17	167.579
#462	ETS2	2	20	22	214.975
#463	GATA5	2	20	22	188.792
#464	PPARD	2	19	21	924.641
#465	TFAP2C	2	19	21	993.414
#466	HOXD10	2	7	9	260.454
#467	FOXC1	2	16	18	624.704
#468	SLC2A4RG	2	23	25	420.306
#469	E2F3	2	21	23	148.48
#470	SOX6	2	17	19	117.942
#471	HMGB2	2	19	21	1453.543
#472	NR1D2	2	13	15	246.721
#473	PITX1	2	19	21	774.627
#474	FOXN3	2	19	21	135.079
#475	IRX5	2	16	18	230.407
#476	CREB3L3	2	13	15	859.848
#477	FOXD4	2	19	21	250.507
#478	CLOCK	2	15	17	157.387
#479	BCL3	2	19	21	619.329
#480	TMEM229A	2	23	25	505.313
#481	TP63	2	5	7	26.229
#482	GRHL3	1	17	18	121.451
#483	SIX4	1	25	26	453.837
#484	NKX2-3	1	21	22	163.842
#485	SRF	1	12	13	58.881
#486	FOXO1	1	20	21	617.379
#487	TSHZ2	1	19	20	123.865
#488	SOX8	1	19	20	383.075
#489	KDM5B	1	12	13	69.189
#490	ZNF215	1	13	14	54.232
#491	ZNF91	1	23	24	516.408
#492	ARNTL	0	12	12	0
#493	FOXP4	0	15	15	0
#494	ZSCAN4	0	15	15	0
#495	LHX2	0	14	14	0
#496	HOXB8	0	14	14	0
#497	BTG2	0	19	19	0
#498	PBX2	0	15	15	0
#499	IRF5	0	11	11	0
#500	LMO4	0	22	22	0