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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	SP3	53	2	55	83.666
#2	TADA3	52	4	56	6293.855
#3	RFXAP	49	0	49	0
#4	SP4	49	5	54	308.596
#5	ZNF189	48	2	50	138.419
#6	HDAC2	47	2	49	102.684
#7	CNBP	45	3	48	4772.404
#8	ZHX1	39	5	44	1158.681
#9	NR2C1	38	6	44	3962.914
#10	NFE2L2	37	4	41	470.629
#11	STAT4	37	6	43	1619.487
#12	NR1H2	35	7	42	1720.794
#13	POU2F1	35	3	38	1776.173
#14	ATF1	34	1	35	28.8
#15	CREB1	34	8	42	5502.299
#16	AHR	34	3	37	2498.921
#17	PURA	33	8	41	1037.701
#18	ZHX2	32	5	37	2136.286
#19	CEBPA	32	9	41	3945.641
#20	SNAPC2	31	10	41	525.824
#21	GABPA	30	4	34	1450.443
#22	ZKSCAN4	29	5	34	453.928
#23	BCL11B	29	3	32	404.104
#24	ZNF217	29	8	37	1662.35
#25	NFYB	29	11	40	2740.034
#26	REXO4	28	4	32	324.854
#27	BTAF1	28	5	33	208.523
#28	ZBTB48	27	7	34	991.605
#29	ZNF277	27	8	35	589.781
#30	ZNF175	26	6	32	1873.216
#31	FBXW7	26	2	28	2287.186
#32	NPAT	25	4	29	1147.502
#33	ETS1	25	5	30	743.385
#34	BLZF1	25	7	32	768.913
#35	TCEAL1	25	13	38	1354.091
#36	MYNN	25	12	37	989.266
#37	TRIM28	25	6	31	823.891
#38	ELF1	25	10	35	1511.182
#39	PHF1	25	2	27	298.759
#40	NFIL3	25	6	31	1337.384
#41	ZNF438	24	6	30	1570.398
#42	RXRB	24	6	30	199.112
#43	CSRNP1	24	6	30	1902.717
#44	FOXD4L5	24	1	25	72.524
#45	RNF4	24	10	34	6445.555
#46	FOXJ3	24	9	33	3119.364
#47	ZNF140	24	10	34	2064.031
#48	HOMEZ	23	3	26	73.267
#49	CNOT8	23	1	24	9.754
#50	ZNF187	23	2	25	49.888
#51	ZNF33B	23	8	31	1340.807
#52	SMAD4	23	4	27	695.203
#53	ZKSCAN3	23	3	26	575.545
#54	RXRA	23	6	29	2101.135
#55	TFEB	23	9	32	497.767
#56	GABPB1	23	11	34	5801.277
#57	ETV3	22	5	27	629.517
#58	ELF4	22	4	26	3057.348
#59	FOXP1	22	3	25	618.718
#60	ZNF69	22	10	32	1475.811
#61	LASS5	21	11	32	4641.242
#62	TRIM22	21	8	29	2381.675
#63	CIR1	21	9	30	2186.197
#64	NFE2	21	12	33	4049.041
#65	NFE2L1	21	10	31	2540.628
#66	TAF5	21	13	34	2659.769
#67	AATF	21	9	30	4702.177
#68	STRN3	21	6	27	537.771
#69	RUNX3	21	5	26	2403.626
#70	SUPT6H	21	6	27	243.111
#71	TP53	21	7	28	528.589
#72	ZC3H8	21	14	35	4897.077
#73	GATA3	21	9	30	2992.496
#74	SNAPC4	20	5	25	874.303
#75	RELA	20	9	29	1995.378
#76	TCF3	20	8	28	1797.192
#77	TCF7	20	7	27	1929.052
#78	ELF2	20	3	23	1026.408
#79	ETS2	20	3	23	741.118
#80	DMTF1	20	12	32	410.498
#81	NR3C2	20	8	28	1631.311
#82	E4F1	20	4	24	254.132
#83	RFXANK	20	4	24	211.961
#84	TSHZ3	20	8	28	3284.36
#85	FLI1	20	8	28	1050.543
#86	ARID4A	20	4	24	302.652
#87	FOSL2	20	8	28	1813.113
#88	ZNF91	19	11	30	1821.393
#89	MSL3	19	5	24	329.831
#90	GTF2I	19	6	25	1125.121
#91	LEF1	19	3	22	143.005
#92	ZNF193	19	10	29	3118.47
#93	ZBTB17	19	12	31	1288.994
#94	SOX30	19	3	22	4218.78
#95	MZF1	19	6	25	575.609
#96	HIF1A	19	11	30	2915.021
#97	ECSIT	19	11	30	725.864
#98	RAX2	18	12	30	2902.876
#99	TCF25	18	5	23	133.831
#100	CEBPD	18	5	23	813.007
#101	RFX5	18	12	30	1851.517
#102	ZNF3	18	6	24	759.997
#103	TAF7	17	12	29	514.472
#104	CBFB	17	9	26	624.04
#105	TAF12	17	9	26	2542.559
#106	TAF1B	17	12	29	426.193
#107	SCAND1	17	8	25	454.755
#108	MLLT10	17	12	29	3106.743
#109	E2F5	17	10	27	2940.894
#110	ZSCAN21	16	10	26	1627.184
#111	CBFA2T3	16	13	29	4619.912
#112	MNT	16	9	25	2291.509
#113	REL	16	10	26	2056.702
#114	ZNF394	16	7	23	2034.492
#115	KLF9	16	5	21	592.96
#116	GAS7	16	7	23	2539.718
#117	BCL6	15	8	23	1592.204
#118	LZTR1	15	6	21	473.63
#119	SMAD3	15	13	28	3389.055
#120	FOXD4L4	15	6	21	1627.23
#121	ZNF236	15	12	27	1064.518
#122	ZNF444	15	9	24	910.935
#123	STAT5A	15	4	19	668.401
#124	HMGB2	15	9	24	1574.26
#125	EOMES	15	10	25	4796.166
#126	RBPJ	15	9	24	1954.022
#127	SMAD9	15	9	24	686.028
#128	AFF4	15	8	23	1200.428
#129	ZNF281	15	13	28	1580.851
#130	IRX1	15	3	18	225.028
#131	ZNF45	15	9	24	1065.592
#132	ZNF133	15	11	26	1166.351
#133	PLSCR1	14	13	27	3136.645
#134	MTA1	14	5	19	1023.322
#135	HNRNPK	14	11	25	587.356
#136	ATF3	14	7	21	2335.525
#137	CEBPB	14	12	26	1595.578
#138	VAV1	14	13	27	1053.479
#139	KLF12	14	11	25	8689.065
#140	HMG20A	14	13	27	1866.914
#141	CTBP1	14	7	21	1065.259
#142	ASCL2	14	9	23	1844.884
#143	SOX13	14	6	20	1120.841
#144	NR4A2	14	5	19	1377.704
#145	TGIF2	14	15	29	1031.294
#146	ZNF167	14	13	27	1955.058
#147	ZNF24	13	7	20	1686.818
#148	TAL1	13	1	14	137.256
#149	TAF4B	13	10	23	1356.379
#150	TADA2A	13	12	25	511.805
#151	GTF2H4	13	9	22	543.292
#152	PPARD	13	5	18	79.507
#153	RCAN1	13	8	21	4088.061
#154	IKZF3	13	6	19	1880.822
#155	ZKSCAN5	13	10	23	1807.812
#156	FOSB	13	4	17	59.088
#157	CBFA2T2	13	12	25	2075.369
#158	USF2	13	8	21	1361.923
#159	POU5F1	13	11	24	1467.55
#160	SCML1	13	12	25	1346.916
#161	RB1	13	10	23	487.735
#162	BACH2	13	11	24	3442.588
#163	ADNP2	13	16	29	1011.081
#164	ZFP36L1	13	7	20	3384.148
#165	TSHZ2	13	6	19	325.166
#166	ZRANB2	13	5	18	2730.69
#167	SPEN	13	16	29	3292.349
#168	ZFHX3	12	11	23	3353.148
#169	ZNF148	12	9	21	1250.214
#170	ZNF75D	12	15	27	2045.519
#171	MLL	12	16	28	1329.22
#172	SREBF2	12	13	25	954.122
#173	SRF	12	10	22	1906.047
#174	ZNF434	12	7	19	134.902
#175	RFX1	12	15	27	3740.307
#176	AEBP1	12	13	25	3836.152
#177	PA2G4	12	12	24	5516.42
#178	SOLH	12	6	18	1619.847
#179	FOXG1	12	6	18	1231.367
#180	ZNF213	12	13	25	1813.496
#181	GATA1	12	10	22	1857.183
#182	SPIB	12	8	20	1099.986
#183	TSC22D2	12	13	25	1750.768
#184	SLC2A4RG	12	6	18	1050.744
#185	ESRRA	12	12	24	1025.878
#186	ZNF202	12	9	21	337.718
#187	HMG20B	12	10	22	1237.602
#188	HOXC13	12	4	16	415.965
#189	IKZF4	12	7	19	598.156
#190	DBP	11	15	26	2108.4
#191	TFE3	11	12	23	3835.447
#192	ADNP	11	12	23	2683.524
#193	NFX1	11	8	19	2635.202
#194	MXD1	11	4	15	1679.004
#195	PLAG1	11	8	19	1796.992
#196	FOXP4	11	13	24	1085.384
#197	RARA	11	12	23	2940.926
#198	VENTX	11	12	23	1183.06
#199	ZNF33A	11	11	22	6366.533
#200	MSRB2	11	13	24	1973.68
#201	ZNF18	11	10	21	2857.997
#202	MAFG	11	11	22	943.441
#203	ZNF35	11	11	22	1106.626
#204	TCF12	11	6	17	822.609
#205	CITED2	10	11	21	2160.721
#206	STAT3	10	15	25	1847.284
#207	ARID3A	10	11	21	2123.67
#208	TAF13	10	8	18	658.685
#209	ZNF628	10	13	23	365.65
#210	ZNF232	10	14	24	5372.652
#211	TSC22D4	10	11	21	2350.224
#212	FOXO4	10	16	26	2278.224
#213	ERF	10	9	19	4123.039
#214	ZBTB25	10	11	21	1370.025
#215	DRAP1	10	10	20	888.893
#216	TSHZ1	10	17	27	1426.525
#217	MAFB	10	14	24	4943.68
#218	FOXO1	10	11	21	761.939
#219	FOXD2	10	4	14	393.869
#220	ZSCAN18	10	10	20	1016.071
#221	ZNF83	10	7	17	215.636
#222	E2F2	10	17	27	3911.912
#223	NR1H3	9	13	22	5737.731
#224	MAF	9	15	24	1970.724
#225	SIN3A	9	13	22	1365.897
#226	ATF4	9	13	22	1139.881
#227	CREBBP	9	12	21	2620.071
#228	ETV6	9	15	24	1371.946
#229	TAF4	9	12	21	1867.658
#230	LASS2	9	12	21	1012.124
#231	GTF2H3	9	13	22	1278.675
#232	HNRNPAB	9	13	22	2289.47
#233	ZNF174	9	12	21	625.177
#234	TAF5L	9	10	19	171.197
#235	JDP2	9	13	22	2883.337
#236	TRPS1	9	11	20	4219.317
#237	YEATS4	9	8	17	203.647
#238	SATB1	9	15	24	1060.15
#239	CBL	9	16	25	3532.166
#240	E2F6	9	6	15	362.465
#241	NFKB2	9	11	20	1281.944
#242	HDAC1	9	12	21	1855.281
#243	SP140	9	12	21	1003.217
#244	TGIF1	9	16	25	4340.936
#245	FOXN2	9	9	18	342.941
#246	C5orf41	9	12	21	1843.788
#247	POU2F2	9	11	20	4674.176
#248	SNAPC5	9	7	16	160.296
#249	LASS6	9	15	24	2878.531
#250	CCRN4L	8	12	20	1127.905
#251	PBX2	8	10	18	1827.619
#252	HSF2	8	13	21	420.837
#253	ZFP42	8	14	22	800.964
#254	ONECUT2	8	6	14	299.47
#255	KLF4	8	21	29	3639.034
#256	ZEB2	8	9	17	1876.48
#257	NR4A3	8	10	18	1055.034
#258	PLAGL2	8	10	18	2911.434
#259	YY1	8	7	15	4886.119
#260	DDIT3	8	14	22	992.036
#261	PHTF1	8	10	18	1756.343
#262	NR2C2	8	7	15	277.857
#263	CSDA	8	18	26	1005.819
#264	TRERF1	8	11	19	1459.573
#265	MYCL1	8	4	12	764.834
#266	ARNTL	8	11	19	3981.215
#267	MYC	8	8	16	1434.708
#268	SOX8	8	9	17	715.648
#269	ELK1	8	11	19	1943.762
#270	KLF10	8	14	22	2148.149
#271	NOTCH1	8	8	16	1622.915
#272	MTF1	8	12	20	381.263
#273	NFIC	8	12	20	520.448
#274	IRF8	8	12	20	1963.59
#275	TEF	7	15	22	1114.041
#276	ZNF323	7	14	21	1160.553
#277	AHCTF1	7	10	17	663.673
#278	ZNF446	7	14	21	3090.993
#279	NME2	7	14	21	2661.063
#280	MEIS1	7	5	12	1042.893
#281	HHEX	7	11	18	2193.056
#282	TSC22D3	7	7	14	513.094
#283	ZNF71	7	11	18	5576.357
#284	STAT1	7	8	15	2953.006
#285	THRA	7	10	17	2356.906
#286	MEF2A	7	14	21	815.424
#287	CSRNP2	7	13	20	888.346
#288	NCOR1	7	9	16	1004.619
#289	PBX4	7	21	28	2985.154
#290	TCF4	7	11	18	948.833
#291	FOS	7	9	16	208.614
#292	HOXA6	7	9	16	2200.065
#293	UBN1	7	13	20	499.885
#294	BHLHE40	7	10	17	1253.4
#295	STAT2	7	9	16	3263.804
#296	TFAM	7	8	15	317.08
#297	NFIX	7	13	20	2190.203
#298	DMRT1	7	4	11	207.161
#299	HOPX	7	13	20	1516.973
#300	PURB	7	12	19	377.398
#301	FOXO3	7	21	28	1306.68
#302	PBX3	7	14	21	4271.303
#303	SLC30A9	7	8	15	704.141
#304	GATAD2A	7	11	18	1892.805
#305	TCF7L2	7	17	24	2723.532
#306	SREBF1	7	12	19	2419.277
#307	EGR1	6	6	12	467.341
#308	HOXB7	6	15	21	2516.878
#309	MLX	6	9	15	2832.951
#310	ELK4	6	15	21	1818.54
#311	MYPOP	6	17	23	1568.932
#312	BATF	6	15	21	566.756
#313	IRF3	6	10	16	992.402
#314	HOXC4	6	9	15	621.583
#315	HIRA	6	7	13	118.783
#316	PFDN1	6	12	18	799.53
#317	SMAD5	6	17	23	735.968
#318	MAX	6	9	15	1308.789
#319	TFDP1	6	21	27	2052.326
#320	ZKSCAN1	6	12	18	1083.568
#321	TARDBP	6	17	23	2316.667
#322	ZXDA	6	20	26	3927.383
#323	HOXB4	6	12	18	1337.699
#324	ZNF169	6	14	20	742.718
#325	ALS2CR8	6	13	19	936.158
#326	REST	6	8	14	344.933
#327	SMAD2	5	13	18	2741.042
#328	NFKB1	5	14	19	2898.723
#329	CTCF	5	17	22	1007.12
#330	GCFC1	5	16	21	947.27
#331	BCL3	5	18	23	3401.031
#332	RERE	5	14	19	1625.134
#333	CREBL2	5	6	11	380.332
#334	SALL2	5	10	15	432.683
#335	TBX1	5	8	13	3191.025
#336	CREB3	5	12	17	1492.953
#337	SPI1	5	13	18	1001.514
#338	SP1	5	22	27	831.036
#339	ZNF397	5	10	15	1075.735
#340	RBCK1	5	11	16	809.129
#341	ZFP90	5	13	18	2205.887
#342	UHRF1	5	15	20	1665.178
#343	FUBP1	5	11	16	172.417
#344	BATF3	5	14	19	2684.912
#345	HOXB1	5	9	14	3297.855
#346	RORA	5	12	17	1874.849
#347	ZKSCAN2	5	13	18	846.017
#348	CREB3L4	5	14	19	1146.941
#349	NFYA	5	15	20	378.176
#350	SIX5	5	13	18	2637.932
#351	TRIM25	4	15	19	1578.169
#352	TSC22D1	4	12	16	141.867
#353	CREB5	4	11	15	321.424
#354	PBX1	4	7	11	107.316
#355	PPARG	4	13	17	841.544
#356	BATF2	4	15	19	559.214
#357	ZNF85	4	6	10	214.266
#358	ZNF274	4	11	15	744.566
#359	E2F1	4	13	17	1900.435
#360	ZNF138	4	14	18	927.189
#361	VDR	4	18	22	483.055
#362	MECOM	4	3	7	55.977
#363	IRF2	4	14	18	941.553
#364	ETV7	4	10	14	1890.151
#365	ZSCAN2	4	9	13	303.973
#366	MITF	4	19	23	2489.867
#367	POU6F1	4	22	26	1556.88
#368	CUX1	4	14	18	321.15
#369	ARNT	4	14	18	738.525
#370	ZNF219	4	15	19	1233.667
#371	SPIC	4	6	10	235.647
#372	ZFPM1	4	15	19	1136.33
#373	TBX19	4	20	24	505.172
#374	CREBZF	4	18	22	317.313
#375	ATF2	4	10	14	149.617
#376	MTA2	4	13	17	777.547
#377	CREB3L2	4	21	25	1357.773
#378	ZSCAN16	4	14	18	85.124
#379	MEF2D	4	11	15	788.203
#380	JUND	4	15	19	2466.086
#381	TULP4	4	20	24	3623.9
#382	EGR2	3	8	11	1167.59
#383	TRIM29	3	7	10	728.062
#384	GATAD2B	3	14	17	416.302
#385	PKNOX1	3	14	17	368.847
#386	ATF6	3	12	15	1871.722
#387	BTG2	3	13	16	781.042
#388	CEBPE	3	19	22	2747.203
#389	JUN	3	9	12	1368.017
#390	HES6	3	10	13	271.848
#391	ZNF263	3	17	20	914.051
#392	MEF2C	3	17	20	925.95
#393	CUX2	3	15	18	840.389
#394	LCOR	3	12	15	463.116
#395	ZNF238	3	19	22	1332.763
#396	TFAP4	3	12	15	2899.974
#397	MSC	3	15	18	336.037
#398	PGBD1	3	10	13	385.03
#399	USF1	3	14	17	1452.368
#400	E2F3	3	10	13	119.487
#401	ZNF256	3	11	14	277.73
#402	HOXB6	3	9	12	509.339
#403	RELB	3	13	16	2101.038
#404	NFATC3	3	11	14	4819.177
#405	ZNF498	3	14	17	724.272
#406	ATF5	2	16	18	3753.098
#407	KLF3	2	15	17	186.151
#408	HINFP	2	8	10	546.483
#409	GATAD1	2	14	16	1676.503
#410	KLF11	2	15	17	567.211
#411	IRF7	2	12	14	1394.908
#412	RUNX1	2	15	17	226.615
#413	TFCP2	2	21	23	412.321
#414	ATF6B	2	16	18	1125.386
#415	NFATC1	2	16	18	358.009
#416	IRX3	2	13	15	1524.732
#417	PCGF6	2	10	12	21.557
#418	GTF2H2	2	5	7	11.947
#419	ZHX3	2	18	20	949.888
#420	SATB2	2	11	13	78.168
#421	NOLC1	2	11	13	269.361
#422	TCF20	2	15	17	1229.664
#423	ZNF500	2	15	17	836.292
#424	MESP1	2	12	14	825.385
#425	RFX3	2	16	18	224.124
#426	SCMH1	2	13	15	1674.302
#427	IRF9	2	13	15	205.071
#428	MBD1	2	13	15	232.287
#429	NR1D2	2	15	17	171.936
#430	PRDM1	2	12	14	606.189
#431	KLF17	2	16	18	423.802
#432	KLF6	2	14	16	222.629
#433	ZXDC	2	12	14	173.129
#434	PTTG1	2	20	22	774.116
#435	NR2E3	2	9	11	34.509
#436	LHX6	2	12	14	133.042
#437	SOX4	2	18	20	442.18
#438	ZSCAN22	1	11	12	42.94
#439	C1orf85	1	15	16	85.616
#440	IRF1	1	12	13	258.835
#441	FOXC2	1	17	18	63.576
#442	ELK3	1	17	18	79.724
#443	TFAP2E	1	14	15	70.707
#444	NR2F2	1	16	17	395.048
#445	GLIS3	1	12	13	306.837
#446	SCRT1	1	8	9	44.138
#447	STAT6	1	12	13	2302.317
#448	HOXA7	1	10	11	1288.461
#449	CREM	1	13	14	11.659
#450	GATA2	1	12	13	69.607
#451	TFDP2	1	15	16	1346.746
#452	NR2F6	1	12	13	241.686
#453	HSF4	1	13	14	23.133
#454	CLOCK	1	10	11	427.957
#455	HEY1	1	12	13	202.769
#456	MTA3	1	17	18	533.65
#457	ZNF135	1	14	15	46.445
#458	HOXA10	1	16	17	79.94
#459	ZFP37	1	11	12	24.729
#460	NFIB	1	9	10	40.546
#461	SOX15	1	13	14	49.533
#462	HOXA9	1	9	10	23.776
#463	NFIA	1	9	10	373.661
#464	IKZF1	1	8	9	90.619
#465	HSF1	1	13	14	19.25
#466	RORC	1	15	16	70.288
#467	HOXA5	0	10	10	0
#468	RHOXF1	0	15	15	0
#469	CTNNB1	0	11	11	0
#470	XBP1	0	18	18	0
#471	ZSCAN5A	0	16	16	0
#472	SNAI3	0	17	17	0
#473	ZSCAN29	0	12	12	0
#474	HOXA2	0	16	16	0
#475	PHF5A	0	13	13	0
#476	NKX3-1	0	15	15	0
#477	EPAS1	0	19	19	0
#478	MEOX1	0	10	10	0
#479	HOXB2	0	12	12	0
#480	STAT5B	0	15	15	0
#481	ZNF80	0	7	7	0
#482	ZNF268	0	15	15	0
#483	HMBOX1	0	15	15	0
#484	NR3C1	0	16	16	0
#485	PPARA	0	12	12	0
#486	IRF4	0	12	12	0
#487	RUNX2	0	18	18	0
#488	ZNF197	0	13	13	0
#489	ZNF134	0	12	12	0
#490	ZNF93	0	8	8	0
#491	EBF1	0	9	9	0
#492	NFXL1	0	9	9	0
#493	ZNF37A	0	17	17	0
#494	CNOT7	0	13	13	0
#495	TCFL5	0	14	14	0
#496	IRF5	0	7	7	0
#497	PCGF2	0	10	10	0
#498	ZNF41	0	12	12	0
#499	NFE2L3	0	12	12	0
#500	PRDM2	0	12	12	0