Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	ZNF91	47	1	48	33.859
#2	ZBTB38	42	3	45	71.735
#3	MAX	39	3	42	147.767
#4	STAT1	35	7	42	703.431
#5	STAT3	34	5	39	285.957
#6	RELA	32	6	38	6846.977
#7	TP53	30	5	35	2628.298
#8	NFAT5	30	0	30	0
#9	ZNF148	27	6	33	353.47
#10	ENO1	27	7	34	3062.875
#11	GATAD1	27	3	30	676.754
#12	SMAD5	26	6	32	463.912
#13	SOX9	26	6	32	3668.212
#14	SMAD3	25	11	36	1471.696
#15	ZFP36L2	25	7	32	455.295
#16	ATF6	24	7	31	909.796
#17	RARG	24	8	32	1252.867
#18	TCF7L2	24	11	35	1340.78
#19	TFAP2C	23	7	30	982.274
#20	GTF2I	23	5	28	722.114
#21	CREB1	23	5	28	102.178
#22	SNAPC2	22	7	29	19675.826
#23	TFAM	22	11	33	1123.049
#24	MAFB	22	7	29	732.048
#25	KLF6	22	7	29	2761.268
#26	ZKSCAN5	21	5	26	645.956
#27	NFX1	21	9	30	1769.63
#28	MTA1	21	8	29	400.633
#29	E2F5	20	10	30	3012.684
#30	AR	20	8	28	1250.159
#31	TEAD1	20	4	24	271.619
#32	ZNF24	20	11	31	434.299
#33	DLX6	20	9	29	2288.901
#34	HSF1	20	10	30	248.502
#35	SOLH	20	8	28	345.959
#36	MYCL1	20	8	28	1328.874
#37	E2F4	20	9	29	477.543
#38	FOXD3	19	8	27	2233.975
#39	NKX3-1	19	9	28	1472.224
#40	JUND	19	8	27	19434.775
#41	ALS2CR8	19	7	26	2190.588
#42	BCL6	19	9	28	2649.091
#43	GTF2H3	19	5	24	1101.051
#44	LHX5	19	8	27	964.968
#45	NR4A2	18	7	25	8428.222
#46	E2F2	18	8	26	2101.184
#47	RORC	18	2	20	503.389
#48	NR2E3	18	6	24	1699.954
#49	ZNF33B	18	5	23	465.733
#50	YY1	18	9	27	753.514
#51	ARNTL	18	6	24	141.404
#52	GTF2H4	17	2	19	32.742
#53	KLF15	17	12	29	2105.998
#54	FOXE3	17	10	27	1871.241
#55	POU2F2	17	10	27	1658.803
#56	ELF1	17	3	20	101.618
#57	NKX2-5	17	13	30	5611.073
#58	NR4A1	17	2	19	208.837
#59	HOXA7	17	13	30	3261.734
#60	KDM5A	17	9	26	434.813
#61	RARA	17	10	27	757.539
#62	EVX1	17	4	21	315.02
#63	NOLC1	17	9	26	318.763
#64	KLF4	16	6	22	482.351
#65	ZKSCAN1	16	4	20	2011.493
#66	REL	16	8	24	2423.551
#67	FEV	16	6	22	735.684
#68	EGR3	16	2	18	820.38
#69	NFATC3	16	9	25	1439.626
#70	SP1	16	14	30	1502.567
#71	TSC22D3	16	11	27	1751.499
#72	MBD1	16	5	21	217.193
#73	NKX3-2	16	12	28	1309.794
#74	HEY2	16	7	23	446.19
#75	TEAD4	16	11	27	523.578
#76	SOX2	16	12	28	958.887
#77	HOXA4	16	10	26	1773.606
#78	FOS	16	6	22	2345.528
#79	MTA2	15	9	24	992.867
#80	ETS2	15	7	22	1254.715
#81	PBX1	15	11	26	327.253
#82	MYBL2	15	10	25	1353.499
#83	NFIC	15	11	26	1421.766
#84	NR1D2	15	14	29	634.329
#85	BNC1	15	10	25	1671.725
#86	JUNB	15	1	16	50.081
#87	FOXF2	15	6	21	613.611
#88	TAF13	15	11	26	1619.44
#89	SRF	15	9	24	1460.26
#90	TADA2A	15	12	27	1607.111
#91	BHLHE40	15	11	26	819.466
#92	SPEN	15	8	23	993.493
#93	ZEB2	14	12	26	2273.049
#94	FOXN2	14	6	20	417.955
#95	CREBBP	14	11	25	2293.777
#96	ESRRA	14	15	29	1046.93
#97	SIX6	14	5	19	427.681
#98	HMGA1	14	10	24	493.326
#99	ZNF446	14	14	28	6073.855
#100	JUN	14	10	24	732.542
#101	MEOX1	14	14	28	4886.205
#102	ZNF117	14	11	25	1559.596
#103	ASCL2	14	11	25	452.072
#104	STAT6	14	8	22	334.641
#105	HMGA2	14	15	29	1920.708
#106	NPAT	14	18	32	3165.403
#107	FOXH1	14	10	24	1543.389
#108	NR2F6	14	6	20	2249.647
#109	KLF11	14	4	18	460.769
#110	ZNF202	14	11	25	1605.755
#111	TSC22D2	14	15	29	9981.276
#112	PROX1	14	10	24	1683.18
#113	ZNF45	14	6	20	223.833
#114	ESRRG	13	13	26	1388.394
#115	POU4F1	13	15	28	1718.688
#116	SIX1	13	11	24	918.096
#117	SCAND2	13	10	23	1094.772
#118	CITED1	13	6	19	529.611
#119	TLX1	13	17	30	2456.541
#120	PAX7	13	9	22	1311.323
#121	SOX17	13	11	24	1781.616
#122	HCLS1	13	8	21	1146.575
#123	HOXA6	13	9	22	1584.609
#124	SOX10	13	11	24	1343.636
#125	GABPA	13	7	20	321.483
#126	DBP	13	12	25	1647.814
#127	NR2E1	13	5	18	593.996
#128	DLX4	13	10	23	1079.519
#129	KLF12	13	13	26	5125.509
#130	ETV2	13	8	21	1118.376
#131	STRN3	13	10	23	1207.261
#132	THRB	13	7	20	302.193
#133	SOX21	13	12	25	4615.175
#134	RORA	13	11	24	410.333
#135	NFATC1	13	7	20	1892.783
#136	NANOG	13	11	24	900.257
#137	FOXN3	13	10	23	917.273
#138	HLF	12	12	24	1582.586
#139	IKZF1	12	11	23	1890.103
#140	ESR1	12	12	24	577.886
#141	RB1	12	12	24	577.013
#142	SATB1	12	13	25	1575.993
#143	SP4	12	12	24	988.747
#144	HOXA9	12	11	23	1572.277
#145	PKNOX1	12	12	24	2120.121
#146	FOXJ1	12	12	24	1246.046
#147	ETV5	12	12	24	1015.024
#148	TADA3	12	13	25	1069.312
#149	CEBPE	12	13	25	1491.483
#150	ZFHX4	12	10	22	1155.445
#151	ZSCAN18	12	11	23	1788.289
#152	MZF1	12	8	20	1730.35
#153	ZNF434	12	12	24	1684.8
#154	TFCP2L1	12	17	29	2324.281
#155	ZNF444	12	9	21	993.823
#156	SOX1	12	11	23	1441.066
#157	ZFHX3	12	8	20	1823.275
#158	HSF2	12	8	20	1288.436
#159	HOXB2	12	8	20	1398.87
#160	BTG2	12	7	19	413.495
#161	EN2	12	12	24	1109.334
#162	ARNTL2	12	9	21	1297.17
#163	MSC	12	9	21	983.919
#164	SPDEF	12	5	17	349.764
#165	ARNT2	12	6	18	753.458
#166	FOXN1	12	9	21	1029.572
#167	ZNF197	12	9	21	1810.92
#168	RORB	11	11	22	1328.123
#169	NKX2-1	11	9	20	730.564
#170	OVOL1	11	11	22	395.778
#171	PRRX1	11	10	21	830.422
#172	STAT5A	11	9	20	1196.485
#173	TBX4	11	11	22	1070.279
#174	FOSL1	11	10	21	3734.691
#175	FOXD2	11	12	23	2099.941
#176	TAF4	11	14	25	1243.977
#177	HEYL	11	11	22	1183.519
#178	EGR4	11	5	16	160.795
#179	SIM1	11	11	22	1606
#180	FOXO4	11	11	22	1538.613
#181	PDX1	11	14	25	1759.357
#182	ETS1	11	10	21	973.976
#183	FOXL1	11	10	21	1087.665
#184	KLF1	11	9	20	1692.572
#185	OLIG2	11	14	25	2524.933
#186	HESX1	11	3	14	340.718
#187	SOX30	11	10	21	1485.166
#188	MYOD1	11	7	18	927.988
#189	POU4F2	11	8	19	1101.557
#190	MXD1	11	6	17	362.611
#191	NR1I2	11	13	24	10245.098
#192	SOX18	11	15	26	1201.706
#193	SP140	11	12	23	1521.735
#194	HOPX	11	14	25	1909.261
#195	BCL3	11	10	21	458.432
#196	SOX15	11	11	22	824.358
#197	FOXB1	10	13	23	1252.988
#198	TCF25	10	8	18	817.67
#199	RARB	10	10	20	1051.262
#200	CRX	10	10	20	868.696
#201	TBX10	10	13	23	1636.254
#202	NR5A2	10	9	19	792.127
#203	GSC2	10	10	20	1108.549
#204	TSHZ2	10	13	23	974.567
#205	FOXD1	10	9	19	1413.089
#206	SNAPC5	10	13	23	1278.206
#207	ELK1	10	11	21	1239.229
#208	BARX1	10	17	27	2441.536
#209	CBFA2T2	10	12	22	791.655
#210	AHR	10	11	21	518.765
#211	NKX6-1	10	9	19	1123.656
#212	TFAP2A	10	12	22	1142.809
#213	ASCL1	10	14	24	2509.363
#214	POU4F3	10	14	24	1384.814
#215	NR4A3	10	7	17	572.46
#216	PAX3	10	15	25	1311.249
#217	FOXC2	10	13	23	1541.653
#218	NFYA	10	13	23	540.955
#219	KLF2	10	8	18	1426.647
#220	ESR2	10	12	22	1233.778
#221	LHX3	10	6	16	571.554
#222	ZNF238	10	12	22	1857.357
#223	ST18	10	12	22	1134.961
#224	PRRX2	10	12	22	1344.89
#225	TRIM25	10	5	15	194.901
#226	MAFF	10	6	16	223.039
#227	AFF1	10	12	22	2818.658
#228	NPAS1	10	11	21	1434.476
#229	BACH1	10	11	21	1090.026
#230	ZNF135	10	9	19	1117.023
#231	HNF4A	10	13	23	1414.099
#232	HOXD12	10	7	17	500.131
#233	HNF1B	10	10	20	1017.243
#234	NR1H4	10	13	23	3437.537
#235	MLLT10	10	9	19	1432.493
#236	MEOX2	10	11	21	2383.844
#237	POU3F2	10	15	25	2115.312
#238	MMP14	10	12	22	1375.64
#239	TBX6	9	9	18	625.305
#240	ARNT	9	9	18	345.858
#241	TEF	9	10	19	794.29
#242	TBR1	9	14	23	1353.894
#243	IRF8	9	14	23	1559.583
#244	C11orf9	9	13	22	1420.572
#245	NFIX	9	8	17	818.018
#246	PHOX2A	9	11	20	996.45
#247	HCFC1	9	11	20	315.408
#248	NR6A1	9	8	17	776.154
#249	HOXB3	9	14	23	1336.627
#250	MYT1	9	9	18	690.497
#251	POU3F3	9	7	16	630.141
#252	ATOH1	9	13	22	2216.847
#253	ZSCAN12	9	8	17	662.664
#254	NR3C2	9	8	17	671.06
#255	ZBTB17	9	9	18	393.334
#256	VSX1	9	7	16	426.968
#257	PKNOX2	9	9	18	1016.119
#258	MYF5	9	16	25	1369.392
#259	FOXP3	9	11	20	697.939
#260	CLOCK	9	9	18	592.267
#261	HNF4G	9	12	21	1276.088
#262	NEUROD2	9	8	17	677.537
#263	TP63	9	15	24	1370.512
#264	BATF3	9	8	17	962.662
#265	CSDA	9	13	22	1316.244
#266	SOX4	9	12	21	1660.276
#267	MEF2D	9	6	15	703.366
#268	EGR2	9	7	16	1110.067
#269	CREB3L1	9	7	16	598.748
#270	HOXB9	9	10	19	1371.497
#271	NFIB	9	14	23	912.049
#272	ZNF81	9	11	20	1171.732
#273	BRD8	9	12	21	1104.654
#274	TFAP2B	9	13	22	1955.079
#275	HAND1	9	12	21	905.595
#276	MEF2C	9	12	21	1508.545
#277	PBX2	9	11	20	2203.314
#278	HOXB7	9	12	21	368.364
#279	ZNF236	9	10	19	380.817
#280	DDIT3	9	11	20	911.142
#281	ETV3	9	9	18	683.139
#282	RXRB	9	7	16	442.761
#283	ALX1	9	11	20	1112.825
#284	LMO4	9	9	18	1015.772
#285	TCF3	9	15	24	1214.526
#286	TAF4B	9	10	19	1148.734
#287	WNT5A	9	11	20	1501.893
#288	PTH	9	12	21	1181.313
#289	ZNF155	9	9	18	473.775
#290	FOXE1	9	16	25	2019.184
#291	RXRG	9	14	23	2113.02
#292	MSX2	9	15	24	1022.051
#293	ZNF41	8	9	17	806.174
#294	SPIB	8	5	13	134.103
#295	MAFK	8	13	21	1481.467
#296	ZNF215	8	15	23	1307.519
#297	EPAS1	8	9	17	514.607
#298	POU3F1	8	14	22	921.628
#299	FOXO3	8	9	17	174.971
#300	LHX2	8	11	19	555.701
#301	CUX2	8	13	21	663.578
#302	RCAN1	8	9	17	6856.186
#303	ONECUT2	8	10	18	719.272
#304	EMX1	8	12	20	776.822
#305	DMRT1	8	11	19	809.069
#306	ZSCAN2	8	13	21	654.361
#307	FOXO1	8	9	17	650.701
#308	HOXD13	8	15	23	1961.742
#309	SOX5	8	9	17	741.435
#310	GATA1	8	11	19	748.791
#311	ELK3	8	10	18	2634.548
#312	ALX4	8	14	22	1479.023
#313	ATF5	8	13	21	1609.837
#314	HMX1	8	8	16	576.575
#315	GATA4	8	12	20	1118.448
#316	CBL	8	7	15	506.386
#317	TLX2	8	16	24	1853.435
#318	SIX5	8	12	20	942.878
#319	PITX3	8	12	20	949.436
#320	UBN1	8	8	16	287.872
#321	BHLHE41	8	8	16	647.592
#322	ZNF80	8	14	22	2084.972
#323	FOXA2	8	14	22	1728.723
#324	MECOM	8	16	24	1167.533
#325	HSF4	8	10	18	970.587
#326	LEF1	8	11	19	680.13
#327	MYC	8	5	13	219.717
#328	SIM2	8	12	20	1521.228
#329	TCF21	8	11	19	1443.592
#330	NR2C1	8	7	15	561.432
#331	HOXD3	8	16	24	1013.242
#332	PITX1	8	12	20	508.291
#333	ZFPM2	8	11	19	884.336
#334	FLI1	8	17	25	1050.707
#335	RBPJL	8	12	20	1145.11
#336	SATB2	8	15	23	798.897
#337	HOXD4	8	6	14	390.284
#338	ZNF287	8	11	19	1588
#339	PURA	8	12	20	1014.332
#340	SOX11	8	12	20	913.887
#341	SALL1	8	8	16	1127.5
#342	ZNF3	8	12	20	799.639
#343	TFCP2	8	11	19	1300.69
#344	SMAD1	8	4	12	183.875
#345	TFEB	8	14	22	707.56
#346	ATF6B	8	13	21	1039.664
#347	BACH2	8	15	23	1597.363
#348	HOXB6	8	12	20	1783.103
#349	TRIM22	7	14	21	789.935
#350	FUBP1	7	9	16	691.445
#351	GAS7	7	13	20	2228.165
#352	NFKB2	7	13	20	1019.082
#353	CREBZF	7	13	20	1169.349
#354	NR1I3	7	15	22	1698.59
#355	PAX8	7	15	22	937.624
#356	POU3F4	7	14	21	1243.239
#357	WT1	7	11	18	919.753
#358	ISL1	7	11	18	647.803
#359	ATF3	7	11	18	623.969
#360	ZFP37	7	22	29	2116.541
#361	KLF10	7	9	16	481.566
#362	AEBP1	7	10	17	1140.337
#363	ZIC3	7	10	17	927.879
#364	TFAP4	7	9	16	755.231
#365	EN1	7	17	24	1829.136
#366	SIX3	7	11	18	646.063
#367	RELB	7	11	18	1098.861
#368	SMAD9	7	15	22	1288.22
#369	HR	7	12	19	1159.879
#370	SLC26A3	7	14	21	949.291
#371	RUNX1	7	13	20	410.33
#372	CREM	7	17	24	2406.098
#373	MLL	7	12	19	2919.96
#374	BLZF1	7	13	20	527.025
#375	LZTS1	7	17	24	1572.914
#376	ELF5	7	13	20	328.577
#377	GCM1	7	11	18	1309.265
#378	PRDM2	7	12	19	824.136
#379	ZNF639	7	13	20	1287.91
#380	VAV1	7	13	20	1019.026
#381	HEY1	7	13	20	638.681
#382	MLXIPL	7	11	18	1183.327
#383	POU6F2	7	10	17	890.942
#384	HOXA3	7	18	25	959.848
#385	ZHX3	7	11	18	1091.853
#386	POU1F1	7	11	18	918.674
#387	ERG	7	13	20	956.079
#388	PPARA	7	12	19	731.286
#389	ETV1	7	15	22	1542.618
#390	PRDM1	7	13	20	1058.465
#391	REST	7	14	21	1526.273
#392	POU2F3	7	15	22	780.611
#393	HOXD1	6	11	17	441.432
#394	VENTX	6	11	17	790.994
#395	GLI2	6	12	18	1040.034
#396	RUNX1T1	6	11	17	452
#397	ZNF157	6	13	19	1035.16
#398	CSRNP3	6	12	18	1028.462
#399	VTN	6	13	19	568.876
#400	CREB5	6	8	14	710.58
#401	MYCN	6	15	21	1646.19
#402	MYOG	6	10	16	589.099
#403	THRA	6	15	21	2879.435
#404	TCF15	6	12	18	983.302
#405	TLX3	6	8	14	336.631
#406	NR2F1	6	12	18	562.504
#407	FOSB	6	12	18	500.646
#408	TWIST1	6	14	20	1321.871
#409	TFDP1	6	7	13	111.231
#410	T	6	8	14	1585.481
#411	NR5A1	6	14	20	867.393
#412	EGR1	6	8	14	300.203
#413	NPAS2	6	14	20	793.313
#414	RERE	6	12	18	1329.723
#415	NEUROD1	6	14	20	1222.341
#416	TBX1	6	14	20	1771.87
#417	TAL1	6	13	19	509.961
#418	TCF12	6	9	15	803.158
#419	LHX1	6	8	14	822.04
#420	HES1	6	11	17	636.037
#421	MAF	6	14	20	760.934
#422	FOXG1	6	6	12	576.853
#423	FOXL2	6	11	17	588.993
#424	KDM5B	6	14	20	685.545
#425	HOXD9	6	16	22	988.047
#426	PLAG1	6	11	17	705.639
#427	VDR	6	8	14	1918.545
#428	GBX2	6	9	15	485.55
#429	SPI1	6	12	18	501.712
#430	HOXB8	6	8	14	903.827
#431	ZNF192	6	9	15	547.728
#432	SHOX	6	7	13	594.192
#433	PAX5	6	10	16	1493.423
#434	CDKN2A	6	13	19	2268.004
#435	SNAI2	5	8	13	264.371
#436	MYT1L	5	13	18	964.358
#437	DLX2	5	12	17	1310.496
#438	TRIM29	5	16	21	1054.706
#439	ETV4	5	13	18	554.784
#440	ZNF154	5	14	19	889.094
#441	MYF6	5	11	16	617.015
#442	IKZF3	5	14	19	1189.816
#443	CEBPD	5	10	15	501.663
#444	FOXI1	5	10	15	387.306
#445	LMX1B	5	9	14	243.938
#446	HNF1A	5	12	17	840.944
#447	HOXA2	5	14	19	784.93
#448	IRF5	5	12	17	651.987
#449	NR0B1	5	14	19	1841.377
#450	ZEB1	5	15	20	662.255
#451	TBX2	5	14	19	828.851
#452	ZNF175	5	12	17	899.731
#453	ALX3	5	14	19	516.296
#454	ZNF132	5	14	19	687.546
#455	PPBPL2	5	11	16	778.132
#456	SCRT1	5	11	16	418.641
#457	HOXA11	5	16	21	1112.227
#458	SMAD6	5	9	14	541.376
#459	PEG3	5	16	21	1362.098
#460	EHF	5	16	21	883.553
#461	NRL	4	13	17	629.603
#462	HOXC8	4	15	19	683.95
#463	TFEC	4	16	20	902.6
#464	RUNX2	4	17	21	532.454
#465	TCF4	4	13	17	994.07
#466	TBX5	4	7	11	184.516
#467	KLF9	4	12	16	1247.11
#468	PHOX2B	4	16	20	936.778
#469	ZFP36L1	4	9	13	503.202
#470	RFXAP	4	16	20	543.728
#471	TFDP3	4	15	19	404.547
#472	HMG20B	4	12	16	745.766
#473	HOXB1	4	13	17	548.664
#474	ONECUT1	4	13	17	707.651
#475	BUD31	4	6	10	368.226
#476	NKX2-8	4	9	13	530.061
#477	ETV6	4	13	17	1108.6
#478	IRF4	4	18	22	1756.915
#479	NEUROG1	4	9	13	437.856
#480	TCF7	4	9	13	460.635
#481	HIC1	4	11	15	655.999
#482	HIF3A	4	12	16	736.193
#483	HOXD10	4	10	14	442.044
#484	RUNX3	4	16	20	542.986
#485	NFATC4	3	12	15	295.95
#486	TP73	3	17	20	1247.185
#487	HOXD11	3	14	17	541.609
#488	SRY	3	12	15	332.943
#489	PAX6	3	10	13	356.916
#490	HAND2	3	13	16	658.11
#491	FOXF1	3	15	18	906.495
#492	PPARD	3	10	13	334.84
#493	HOXA1	3	12	15	282.998
#494	PAX4	3	18	21	393
#495	FOSL2	3	14	17	465.315
#496	HOXC5	3	13	16	655.591
#497	NFE2	2	13	15	486.549
#498	POU6F1	2	9	11	184.835
#499	ZNF167	2	11	13	208.643
#500	STAT2	2	16	18	441.596