Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	STAT3	70	4	74	1359.007
#2	FOXO6	63	2	65	2182.837
#3	DBP	62	2	64	950.787
#4	C1orf85	52	2	54	481.112
#5	PCGF6	47	4	51	577.777
#6	TCFL5	43	5	48	658.23
#7	RBCK1	43	4	47	2923.762
#8	CEBPB	41	6	47	2942.29
#9	NFX1	40	4	44	658.664
#10	ARNTL2	38	4	42	752.665
#11	HEY1	37	8	45	1843.459
#12	TAF4	37	6	43	6287.451
#13	ZNF449	36	12	48	6037.156
#14	TCF3	36	2	38	179.403
#15	NOLC1	36	3	39	77.314
#16	FLI1	35	7	42	17569.733
#17	PLAG1	34	3	37	60.385
#18	TFAP2A	33	6	39	2024.242
#19	NFIB	33	5	38	1408.743
#20	NFIX	32	6	38	1601.349
#21	TCF4	32	6	38	3675.005
#22	PHTF1	31	5	36	1184.278
#23	NR0B1	31	6	37	12696.095
#24	NR2F6	31	7	38	5673.121
#25	YY1	29	6	35	273.373
#26	GATA3	27	8	35	3889.189
#27	CNOT8	27	6	33	1030.305
#28	PEG3	26	12	38	2027.456
#29	RORA	25	8	33	2055.185
#30	SCML2	25	3	28	240.155
#31	SATB1	25	7	32	1437.315
#32	ADNP	25	9	34	10435.608
#33	NR1D2	25	6	31	953.341
#34	IRX3	25	3	28	6189.688
#35	TRPS1	25	8	33	1684.348
#36	SCML1	24	7	31	1627.789
#37	RELA	23	8	31	686.997
#38	KLF3	23	5	28	5185.558
#39	E2F7	23	9	32	1173.147
#40	ZHX1	23	9	32	1591.886
#41	ADNP2	22	5	27	2142.144
#42	CREB3L1	22	7	29	639.617
#43	ETS2	22	10	32	907.702
#44	CNBP	21	8	29	1361.315
#45	HMBOX1	21	8	29	2776.76
#46	HOXB3	21	3	24	9652.605
#47	NFE2L3	20	5	25	637.705
#48	CREB3	20	2	22	269.077
#49	MECOM	20	7	27	2693.477
#50	TFDP2	20	3	23	799.828
#51	FOXK1	20	5	25	617.308
#52	SOX4	20	7	27	486.991
#53	IRF2	20	7	27	5417.068
#54	ETV5	20	11	31	3385.429
#55	HNRNPAB	19	6	25	1297.66
#56	PHF1	19	6	25	1055.175
#57	IKZF4	19	9	28	1374.303
#58	FOXO3	18	6	24	579.873
#59	KLF4	18	6	24	503.213
#60	TSHZ1	18	10	28	1049.563
#61	TAF5	18	7	25	548.814
#62	FOXE1	18	8	26	797.879
#63	ZFHX4	18	9	27	1508.653
#64	RUNX3	18	7	25	7296.042
#65	NR1H2	18	7	25	1472.356
#66	IRF7	17	10	27	1257.962
#67	CTBP1	17	7	24	1945.673
#68	FOXD1	17	7	24	4258.255
#69	SRF	17	2	19	929.008
#70	HMG20A	17	9	26	2080.524
#71	CREBBP	17	9	26	2299.635
#72	CDKN2A	17	1	18	3.778
#73	ETV4	17	9	26	13027.96
#74	GATAD2A	17	7	24	924.079
#75	EPAS1	16	6	22	3060.463
#76	CEBPA	16	8	24	9576.863
#77	HOXA5	16	10	26	2081.752
#78	HHEX	16	11	27	1694.07
#79	GLIS2	16	10	26	519.629
#80	CREM	16	9	25	2736.65
#81	ECSIT	16	9	25	1505.617
#82	MYNN	16	10	26	1567.451
#83	TSHZ3	15	9	24	974.714
#84	BHLHE40	15	18	33	2588.22
#85	SIX5	15	8	23	794.867
#86	FOXP2	15	6	21	4596.514
#87	HOXA7	15	8	23	1216.798
#88	NR3C1	15	10	25	1838.971
#89	KLF5	15	9	24	3356.523
#90	ELF2	14	9	23	25807.767
#91	JUND	14	8	22	16409.193
#92	AFF1	14	9	23	1061.14
#93	HOXA9	14	8	22	489.121
#94	KLF10	14	2	16	1350.879
#95	MAFK	14	4	18	124.867
#96	EGR1	14	8	22	2548.876
#97	MNT	14	6	20	9614.475
#98	MKX	14	11	25	4085.244
#99	CREB3L2	14	7	21	499.077
#100	TFE3	14	12	26	3805.267
#101	MSL3	14	5	19	378.658
#102	CBFA2T2	13	7	20	12982.737
#103	EGR4	13	5	18	1765.428
#104	FOXN3	13	6	19	1717.818
#105	HOXA10	13	7	20	363.196
#106	MAX	13	13	26	22664.296
#107	PTTG1	13	8	21	2792.542
#108	KDM5A	13	7	20	573.903
#109	ETV6	13	11	24	1615.674
#110	TULP4	13	8	21	4844.581
#111	TAF12	13	6	19	17352.955
#112	MEIS3P1	13	5	18	884.875
#113	ZC3H8	12	12	24	3096.728
#114	HMX2	12	9	21	1379.604
#115	CSRNP1	12	7	19	14499.953
#116	ZNF207	12	6	18	879.347
#117	NKX3-2	12	6	18	4742.753
#118	ZEB1	12	9	21	1641.497
#119	NCOR1	12	8	20	705.554
#120	ESRRA	12	9	21	2321.49
#121	AHR	12	10	22	1891.945
#122	HOXA3	12	10	22	1013.198
#123	E2F6	12	8	20	2136.944
#124	RB1	12	10	22	569.587
#125	CUX1	11	5	16	488.782
#126	ZNF24	11	9	20	1591.778
#127	RFX5	11	12	23	1149.808
#128	HOXB6	11	5	16	11726.684
#129	PURA	11	6	17	820.174
#130	TCF25	11	7	18	184.267
#131	C5orf41	11	11	22	689.859
#132	DRAP1	11	3	14	411.351
#133	MAFF	11	12	23	3573.282
#134	KLF11	11	6	17	2365.678
#135	JUN	11	8	19	4372.892
#136	RELB	11	8	19	628.661
#137	FOXP1	11	5	16	591.832
#138	HOXA2	11	9	20	12606.214
#139	DLX1	11	11	22	2790.001
#140	ZNF3	11	10	21	1890.092
#141	ZNF281	10	9	19	529.245
#142	YEATS4	10	10	20	4465.059
#143	NR2C2	10	7	17	1615.009
#144	ZNF639	10	8	18	6333.233
#145	NR2F1	10	4	14	749.004
#146	SP1	10	7	17	279.861
#147	SMAD4	10	10	20	268.266
#148	ATF3	10	11	21	2246.808
#149	HOXB9	10	11	21	1122.406
#150	ATF6	10	8	18	1005.293
#151	KLF7	10	7	17	1147.021
#152	E2F1	10	7	17	11647.328
#153	NFAT5	10	5	15	1661.116
#154	NKX1-1	10	11	21	24178.777
#155	SLC30A9	10	10	20	553.512
#156	ZKSCAN1	10	8	18	3217.75
#157	ISL1	10	10	20	6338.345
#158	POU2F1	9	9	18	6229.794
#159	BTAF1	9	9	18	841.1
#160	MZF1	9	7	16	2563.347
#161	SOX9	9	12	21	2088.367
#162	KLF6	9	6	15	199.637
#163	PRRX1	9	11	20	9157.852
#164	PURB	9	13	22	1227.375
#165	CEBPD	9	11	20	1881.453
#166	MMP14	9	8	17	993.439
#167	TWIST2	9	11	20	1151.399
#168	TSC22D3	9	9	18	7323.529
#169	HNF4G	9	7	16	17511.896
#170	NR2F2	9	11	20	564.528
#171	TCF7L2	9	11	20	1033.015
#172	MLL	9	11	20	2965.921
#173	ZNF367	9	4	13	2158.177
#174	HES6	9	4	13	115.785
#175	ETS1	9	14	23	2071.21
#176	TAF4B	9	9	18	960.729
#177	SMAD3	9	7	16	489.677
#178	CREB3L4	9	12	21	7958.767
#179	SCAND3	9	9	18	2232.588
#180	SMAD1	9	8	17	524.333
#181	CBFB	9	11	20	2260.6
#182	BATF3	9	12	21	3382.306
#183	CREBL2	9	10	19	1096.771
#184	ZGPAT	8	9	17	1866.742
#185	NFIA	8	13	21	1833.311
#186	ZNF117	8	10	18	450.591
#187	TEAD4	8	8	16	773.494
#188	ZFP90	8	13	21	8288.218
#189	KLF9	8	9	17	23476.719
#190	HEYL	8	11	19	839.421
#191	TGIF2	8	8	16	7734.877
#192	ARX	8	14	22	955.078
#193	ESRRG	8	7	15	639.751
#194	TAF5L	8	7	15	503.308
#195	SREBF1	8	11	19	10253.331
#196	IRF9	8	7	15	101.489
#197	ZFP36L1	8	8	16	1680.422
#198	MYBL2	8	7	15	228.138
#199	SIN3A	8	9	17	5205.185
#200	PA2G4	8	11	19	1144.33
#201	WT1	8	8	16	737.582
#202	GTF2H2	8	14	22	867.69
#203	KLF12	8	10	18	1691.154
#204	FOSB	8	6	14	1186.074
#205	MGA	8	8	16	778.19
#206	TSC22D1	7	10	17	9158.088
#207	SMAD5	7	10	17	703.722
#208	RBPJ	7	6	13	159.347
#209	JUNB	7	10	17	749.544
#210	PBX1	7	7	14	125.835
#211	CIR1	7	11	18	1816.7
#212	ELK3	7	13	20	1156.757
#213	FOSL1	7	13	20	1528.577
#214	HOXA1	7	10	17	779.773
#215	GATAD2B	7	7	14	329.855
#216	DLX6	7	12	19	5441.753
#217	EGR2	7	3	10	387.099
#218	MLLT10	7	7	14	10947.548
#219	MSX1	7	12	19	3949.912
#220	ZFP37	7	4	11	2959.961
#221	PKNOX1	7	7	14	11168.787
#222	GTF2IRD1	7	9	16	3963.665
#223	SOX13	7	4	11	28.224
#224	ZNF140	7	10	17	11051.318
#225	ZNF131	7	8	15	6774.835
#226	TBX1	7	6	13	162.259
#227	DDIT3	7	11	18	1785.699
#228	EGR3	7	4	11	828.004
#229	TARDBP	7	7	14	535.683
#230	AFF4	6	13	19	1165.642
#231	MAFG	6	8	14	22525.448
#232	NR2C1	6	8	14	920.844
#233	NFE2L1	6	10	16	1779.488
#234	PAX6	6	9	15	691.939
#235	ZNF134	6	7	13	9982.379
#236	NFATC1	6	7	13	127.349
#237	CTNNB1	6	9	15	1026.099
#238	HIRA	6	10	16	6842.345
#239	TRERF1	6	9	15	1421.823
#240	ATF4	6	11	17	344.554
#241	RUNX1	6	9	15	231.569
#242	SREBF2	6	10	16	1681.849
#243	SMAD9	6	9	15	5268.21
#244	NFKB2	6	8	14	318.029
#245	HOXD8	6	11	17	732.681
#246	RFXAP	6	10	16	465.205
#247	ZNF236	6	12	18	645.946
#248	E2F3	6	8	14	2270.504
#249	FOSL2	6	13	19	9635.861
#250	HOXB5	6	8	14	460.175
#251	ZFHX3	6	7	13	135.346
#252	E2F2	6	6	12	135.716
#253	CREB1	6	9	15	577.677
#254	ZXDC	6	7	13	2769.103
#255	HOXC10	6	7	13	688.306
#256	REST	6	7	13	23073.343
#257	VDR	6	10	16	771.216
#258	ATF2	6	7	13	1333.289
#259	GATA2	6	14	20	1872.641
#260	GABPB1	6	8	14	1214.92
#261	MITF	6	5	11	7065.221
#262	ZNF70	6	8	14	734.406
#263	ZKSCAN4	6	7	13	1573.31
#264	SOLH	6	13	19	2352.723
#265	SLC2A4RG	6	6	12	64.41
#266	FOXO4	6	11	17	161.407
#267	ZNF35	6	6	12	19302.4
#268	MEIS2	6	10	16	127.222
#269	POU4F1	6	9	15	2000.543
#270	CITED2	6	9	15	4660.39
#271	ZBTB38	5	8	13	491.301
#272	STAT1	5	10	15	338.004
#273	ZSCAN29	5	7	12	824.364
#274	ZSCAN21	5	6	11	844.175
#275	NR1H3	5	8	13	107.701
#276	HMGA1	5	9	14	720.74
#277	TEAD3	5	9	14	214.03
#278	NR3C2	5	10	15	696.838
#279	CREBZF	5	11	16	431.926
#280	NFXL1	5	8	13	335.526
#281	JDP2	5	7	12	1181.57
#282	UHRF1	5	10	15	3073.598
#283	ZNF397	5	10	15	883.057
#284	PBX3	5	8	13	458.26
#285	TCF7L1	5	9	14	156.831
#286	SIX4	5	12	17	1061.852
#287	ELF4	5	13	18	11094.863
#288	ARID4A	5	8	13	1475.69
#289	ATF5	5	7	12	10310.789
#290	ZKSCAN5	5	11	16	3328.509
#291	BNC1	5	11	16	774.274
#292	TAF1B	5	10	15	326.46
#293	SPEN	5	3	8	4498.685
#294	SOX2	5	10	15	4247.331
#295	GATA6	4	11	15	431.552
#296	SMAD2	4	6	10	878.729
#297	ATF7	4	9	13	1654.159
#298	RXRA	4	8	12	1193.738
#299	HMGB1	4	12	16	2017.66
#300	SNAPC2	4	8	12	787.308
#301	SP4	4	8	12	151.847
#302	ZNF33A	4	8	12	1742.341
#303	FOXM1	4	8	12	545.325
#304	TRIM22	4	11	15	595.833
#305	ZNF165	4	11	15	4659.405
#306	HOXB8	4	7	11	1835.742
#307	GCFC1	4	9	13	218.745
#308	ZNF500	4	12	16	7828.378
#309	MESP1	4	11	15	425.174
#310	BCL3	4	12	16	120.989
#311	PPARG	4	8	12	195.679
#312	ZNF268	4	10	14	133.703
#313	ZNF277	4	11	15	1954.494
#314	IRF1	4	12	16	529.697
#315	TP53	4	14	18	468.616
#316	MEF2C	4	11	15	991.636
#317	ZHX3	4	10	14	217.722
#318	REL	4	11	15	804.545
#319	ZIC2	4	12	16	8799.513
#320	SNAPC5	4	8	12	358.807
#321	C11orf9	4	10	14	8386.599
#322	PPARD	4	7	11	121.109
#323	FOXK2	4	9	13	3064.433
#324	TBP	4	10	14	671.583
#325	TCF19	3	7	10	187.196
#326	NR4A3	3	13	16	1459.266
#327	BHLHE41	3	13	16	829.492
#328	PLSCR1	3	14	17	866.439
#329	ZEB2	3	10	13	119.572
#330	MYC	3	8	11	402.501
#331	ZNF643	3	7	10	4053.124
#332	MXD1	3	10	13	2411.774
#333	CBL	3	9	12	1028.721
#334	LHX2	3	11	14	348.832
#335	BRD8	3	9	12	951.712
#336	ZXDA	3	7	10	886.988
#337	NR4A1	3	7	10	1519.767
#338	LMO4	3	17	20	1397.826
#339	ZNF93	3	10	13	3591.189
#340	ALX1	3	8	11	3353.662
#341	LHX6	3	9	12	230.879
#342	STRN3	3	6	9	3517.822
#343	FUBP1	3	6	9	41.949
#344	LASS6	3	8	11	144.022
#345	BACH1	3	9	12	3699.489
#346	AHCTF1	3	7	10	2499.025
#347	ERF	3	6	9	141.304
#348	ZFPM1	3	11	14	750.434
#349	MSRB2	3	6	9	61.91
#350	ETV1	3	12	15	466.398
#351	HIC1	3	7	10	230.7
#352	EN2	3	11	14	1767.699
#353	CSRNP3	3	15	18	339.979
#354	EOMES	3	6	9	627.017
#355	PPARA	3	12	15	1314.129
#356	TEF	3	10	13	315.268
#357	KLF16	3	14	17	4866.203
#358	HOXB7	3	9	12	202.501
#359	MEF2D	3	9	12	456.439
#360	LEF1	3	7	10	43.464
#361	E2F5	3	10	13	1690.405
#362	HDX	3	9	12	192.811
#363	MLX	3	12	15	2519.714
#364	ELK4	3	13	16	292.936
#365	HSF1	3	10	13	2208.161
#366	STAT5B	3	7	10	138.358
#367	ZNF92	3	7	10	251.905
#368	SALL2	3	9	12	499.282
#369	MTA1	3	5	8	91.359
#370	TRIM25	2	13	15	387.243
#371	HSF2	2	8	10	107.992
#372	XBP1	2	10	12	150.116
#373	DLX2	2	11	13	230.886
#374	CSDA	2	12	14	4450.769
#375	MEIS1	2	11	13	76.194
#376	ARNTL	2	7	9	72.372
#377	TWIST1	2	15	17	1357.796
#378	TEAD1	2	7	9	4214.783
#379	ZNF232	2	12	14	25.354
#380	LASS5	2	10	12	2026.962
#381	NPAT	2	7	9	130.137
#382	ZNF83	2	11	13	850.153
#383	STAT2	2	10	12	350.696
#384	SNAPC4	2	10	12	236.863
#385	ZNF238	2	9	11	58.85
#386	ZNF91	2	12	14	2367.552
#387	SIX1	2	13	15	110.466
#388	FOXJ3	2	11	13	129.671
#389	ZIC1	2	15	17	249.85
#390	ALS2CR8	2	14	16	188.321
#391	GLI3	2	9	11	30.651
#392	FOXN2	2	8	10	7135.119
#393	ZNF33B	2	9	11	68.481
#394	CCRN4L	2	15	17	4120.599
#395	ZNF148	2	9	11	322.091
#396	NFYB	2	11	13	223.051
#397	UBN1	2	5	7	22.521
#398	ZNF274	2	5	7	448.293
#399	SOX6	2	10	12	153.067
#400	ZNF193	2	12	14	471.668
#401	NFATC3	2	9	11	3726.715
#402	HMGA2	2	8	10	34.69
#403	FOXC1	2	11	13	8468.158
#404	ARID3A	2	8	10	1253.822
#405	FBXW7	2	8	10	521.331
#406	FOXP4	2	7	9	364.552
#407	ZHX2	2	11	13	575.985
#408	HES1	2	17	19	190.501
#409	LCOR	2	9	11	2992.513
#410	ZNF85	2	7	9	44.339
#411	FOS	2	10	12	167.14
#412	ZNF75D	2	9	11	131.622
#413	TSC22D4	2	11	13	178.737
#414	KLF2	2	12	14	943.297
#415	NR1H4	2	12	14	63.918
#416	ZNF496	2	8	10	25.815
#417	MSC	1	10	11	26.4
#418	FOXO1	1	5	6	11.171
#419	ZFPM2	1	13	14	251.29
#420	C2orf3	1	11	12	76.815
#421	TGIF1	1	8	9	113.738
#422	NFYA	1	14	15	57.78
#423	BATF2	1	7	8	10.588
#424	ZNF394	1	14	15	2125.708
#425	NFE2L2	1	15	16	305.099
#426	MYCL1	1	8	9	130.42
#427	TEAD2	1	8	9	15907.005
#428	GABPA	1	14	15	56.337
#429	HOXC13	1	9	10	20.404
#430	RCAN1	1	10	11	61.835
#431	ETV2	1	11	12	33.661
#432	NFIL3	1	7	8	93.228
#433	FOXS1	1	8	9	52.22
#434	CNOT7	1	11	12	55.892
#435	BCL6	1	13	14	181.735
#436	NKX3-1	1	9	10	31.138
#437	ZNF215	1	7	8	41.506
#438	ATF1	1	7	8	55.095
#439	TFAM	1	14	15	133.939
#440	TBX2	1	13	14	260.13
#441	HOXD13	1	7	8	140.849
#442	ISL2	1	8	9	103.723
#443	SMAD6	1	10	11	21.22
#444	HOXD1	1	10	11	717.003
#445	NFIC	1	6	7	27.825
#446	GBX2	1	7	8	99.346
#447	ELF1	1	13	14	127.428
#448	SOX12	1	11	12	132.231
#449	ZNF19	1	5	6	13.055
#450	FOXD3	1	8	9	85.321
#451	POU3F2	1	12	13	440.589
#452	TFDP1	1	10	11	1131.795
#453	ETV3	1	10	11	52.198
#454	NRL	1	8	9	184.006
#455	PBX4	1	5	6	70.779
#456	ZNF217	1	11	12	42.499
#457	BACH2	1	13	14	144.825
#458	CREB5	1	9	10	7.095
#459	MTF1	1	8	9	28.497
#460	CITED1	1	8	9	28.807
#461	NOTCH1	1	10	11	481.563
#462	ZNF396	0	9	9	0
#463	ZNF138	0	8	8	0
#464	ZNF323	0	10	10	0
#465	RARA	0	8	8	0
#466	HOXB13	0	11	11	0
#467	MNX1	0	5	5	0
#468	POU6F1	0	12	12	0
#469	MYPOP	0	8	8	0
#470	ZNF287	0	8	8	0
#471	TLX3	0	11	11	0
#472	RFX3	0	7	7	0
#473	PRDM2	0	8	8	0
#474	ELK1	0	8	8	0
#475	LHX1	0	8	8	0
#476	SUPT6H	0	9	9	0
#477	ZNF256	0	10	10	0
#478	SATB2	0	7	7	0
#479	ATF6B	0	7	7	0
#480	ZFP36L2	0	11	11	0
#481	ZNF41	0	7	7	0
#482	DLX4	0	6	6	0
#483	SCAND1	0	15	15	0
#484	ZIC5	0	10	10	0
#485	ZNF192	0	7	7	0
#486	GLIS3	0	12	12	0
#487	ZNF174	0	13	13	0
#488	ZKSCAN3	0	12	12	0
#489	PITX2	0	12	12	0
#490	IRX5	0	11	11	0
#491	ENO1	0	13	13	0
#492	PLAGL2	0	13	13	0
#493	SP3	0	7	7	0
#494	PBX2	0	8	8	0
#495	NR4A2	0	17	17	0
#496	POU4F2	0	9	9	0
#497	WNT5A	0	11	11	0
#498	RERE	0	9	9	0
#499	E2F8	0	9	9	0
#500	TCF12	0	8	8	0