Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	E2F4	102	0	102	0
#2	JUNB	91	5	96	1998.901
#3	ZNF444	87	5	92	214.802
#4	ENO1	78	4	82	3639.874
#5	MSRB2	78	2	80	170.195
#6	MYT1	78	3	81	353.003
#7	SPDEF	69	4	73	837.614
#8	PAX8	68	11	79	1203.454
#9	ZNF219	66	10	76	521.098
#10	RBCK1	65	2	67	93.151
#11	TEAD4	61	6	67	199.989
#12	REST	61	4	65	491.099
#13	REL	60	3	63	3442.839
#14	ZNF91	60	3	63	165.74
#15	MBD1	59	6	65	202.266
#16	NFIL3	58	8	66	388.81
#17	AEBP1	56	6	62	202.826
#18	BATF	55	8	63	776.634
#19	NCOR1	54	8	62	485.004
#20	USF2	52	9	61	1345.382
#21	KLF10	50	9	59	1952.138
#22	ELK1	50	10	60	665.583
#23	TAL1	50	7	57	130.183
#24	NFYB	50	9	59	2204.768
#25	CREB1	47	5	52	345.549
#26	GTF2H3	46	5	51	1253.464
#27	YBX1	45	5	50	5876.725
#28	DLX2	44	11	55	6361.992
#29	MTA1	44	6	50	614.447
#30	CNOT8	44	7	51	2885.061
#31	IRF4	43	8	51	1627.162
#32	ZNF140	42	8	50	1589.215
#33	CREBZF	42	8	50	1031.133
#34	IRF2	42	12	54	3709.885
#35	ZNF217	42	10	52	2181.151
#36	IRF7	41	13	54	1172.392
#37	RARG	39	9	48	762.467
#38	IRF8	39	9	48	2142.8
#39	ZNF3	39	9	48	701.436
#40	BATF3	39	10	49	1747.833
#41	CREBL2	38	8	46	887.631
#42	HIF3A	38	12	50	1008.492
#43	UBP1	37	7	44	1797.935
#44	SMAD2	37	13	50	6811.823
#45	ZNF236	37	6	43	298.516
#46	CREM	37	17	54	2320.417
#47	NR3C1	36	14	50	3269.221
#48	MEF2C	36	1	37	439.467
#49	PBX3	35	12	47	1164.632
#50	NR2C1	34	15	49	3854.588
#51	TCF12	34	19	53	2917.617
#52	ATF6B	34	15	49	1590.762
#53	E2F1	34	11	45	2099.082
#54	FBXW7	34	13	47	2495.219
#55	GCFC1	33	14	47	2807.96
#56	ARNTL2	33	15	48	3110.407
#57	MZF1	33	7	40	225.652
#58	CREB3L2	32	8	40	1290.531
#59	RARA	32	14	46	1155.007
#60	TCF7L2	32	12	44	409.43
#61	STAT3	31	12	43	1704.863
#62	TSC22D2	30	11	41	794.638
#63	ARID4A	30	6	36	405.909
#64	CTCF	30	12	42	3885.338
#65	FOXJ2	30	9	39	392.104
#66	HMG20B	30	15	45	6235.54
#67	BCL6	29	12	41	1296.177
#68	POU2F2	29	8	37	2818.378
#69	ATF1	29	13	42	1719.376
#70	LZTS1	29	13	42	4038.052
#71	TAF12	29	6	35	1109.527
#72	HNF1A	29	11	40	1386.646
#73	NR4A1	29	13	42	257.026
#74	GABPB1	29	22	51	4396.041
#75	EDF1	29	12	41	1091.794
#76	GTF2H4	29	11	40	1773.745
#77	POU5F1B	29	17	46	1776.891
#78	RCOR1	29	8	37	395.552
#79	TFDP1	28	7	35	155.426
#80	HNRNPAB	28	12	40	8240.48
#81	HOXB1	28	15	43	4804.866
#82	AFF1	28	12	40	712.764
#83	PRRX2	27	17	44	1099.999
#84	MTA2	27	13	40	5711.843
#85	NPAT	27	20	47	1827.268
#86	SOX10	26	15	41	898.309
#87	TCF25	26	9	35	792.86
#88	ETV4	26	14	40	1176.151
#89	HEY1	26	3	29	192.64
#90	STRN3	26	10	36	863.59
#91	CREB3	25	15	40	1855.456
#92	PA2G4	25	16	41	1770.424
#93	NOLC1	25	12	37	1210.187
#94	STAT1	24	13	37	3911.123
#95	PBX2	24	12	36	1137.212
#96	TFCP2	23	11	34	1310.81
#97	MYC	23	14	37	1946.557
#98	PURA	23	18	41	1480.139
#99	VAV1	23	16	39	2057.434
#100	ADNP2	23	15	38	1200.075
#101	RERE	22	9	31	1148.464
#102	NR4A2	22	7	29	132.93
#103	TFE3	22	10	32	790.816
#104	RORC	21	9	30	271.782
#105	HINFP	21	11	32	638.857
#106	ZNF24	21	11	32	2151.041
#107	GBX2	21	12	33	749.829
#108	FUBP1	21	20	41	2398.112
#109	DMTF1	21	23	44	5248.074
#110	ZKSCAN1	21	19	40	3134.316
#111	ZNF277	21	10	31	1302.686
#112	NR4A3	21	16	37	1542.642
#113	HOXD1	20	13	33	678.459
#114	HOXA10	20	11	31	100.339
#115	MLLT10	20	14	34	1367.48
#116	TAF5	20	14	34	1493.041
#117	MLX	20	18	38	1140.98
#118	KLF12	20	21	41	1129.64
#119	HNF1B	20	11	31	1945.914
#120	HNRNPK	20	5	25	123.396
#121	FEV	20	13	33	487.731
#122	PLSCR1	20	5	25	156.027
#123	ATF2	20	14	34	566.679
#124	CITED1	20	11	31	1877.805
#125	JUND	19	17	36	1673.185
#126	ELF3	19	15	34	1428.866
#127	GAS7	19	14	33	1540.077
#128	SUPT6H	19	16	35	3051.958
#129	ZNF287	19	10	29	1050.555
#130	TARDBP	19	10	29	870.828
#131	MAFG	19	18	37	5449.704
#132	ZNF83	19	14	33	391.964
#133	HNF4A	19	12	31	1711.166
#134	MNX1	19	9	28	1846.976
#135	ETV1	19	19	38	3205.4
#136	CSRNP2	19	12	31	1415.706
#137	THRB	19	18	37	1493.525
#138	HMGB1	18	14	32	515.082
#139	ZNF134	18	14	32	2558.991
#140	TAF10	18	14	32	2333.746
#141	RB1	18	11	29	987.657
#142	GABPA	18	12	30	1867.187
#143	NFATC4	18	16	34	650.311
#144	RFXANK	18	12	30	644.293
#145	BHLHE40	18	17	35	4097.159
#146	SRF	18	15	33	5271.302
#147	LASS2	18	18	36	2639.83
#148	ZKSCAN5	18	10	28	193.995
#149	KLF5	18	9	27	200.572
#150	TBP	17	18	35	14936.947
#151	NFAT5	17	22	39	1881.675
#152	LASS6	17	22	39	2130.32
#153	ZNF232	17	11	28	312.68
#154	MLL	17	14	31	2709.133
#155	CNOT7	17	18	35	882.029
#156	SP3	17	20	37	2342.135
#157	MAX	17	13	30	1448.31
#158	RUNX3	17	15	32	2239.342
#159	SMAD4	17	11	28	651.091
#160	HCFC1	17	18	35	2540.728
#161	NR1H2	16	15	31	6077.157
#162	ZKSCAN3	16	12	28	1352.134
#163	KLF6	16	16	32	1277.063
#164	TP53	16	13	29	755.751
#165	MSL3	16	16	32	3646.462
#166	E2F6	16	15	31	2016.094
#167	ZNF45	16	18	34	1828.574
#168	STAT5A	15	17	32	1227.3
#169	PHF1	15	15	30	512.092
#170	HMGA1	15	13	28	2216.438
#171	SIM2	15	16	31	3652.765
#172	PLAGL2	15	17	32	2376.493
#173	SMAD5	15	8	23	933.292
#174	NKX2-1	15	10	25	683.144
#175	HR	15	14	29	217.74
#176	TADA2A	15	10	25	1410.119
#177	VAX2	15	15	30	608.332
#178	ZNF131	15	20	35	1763.243
#179	PTTG1	15	11	26	2161.709
#180	BRD8	15	21	36	9126.15
#181	NR2F6	15	14	29	2029.897
#182	NFE2L3	15	15	30	822.996
#183	BUD31	15	14	29	2902.087
#184	MAFF	15	19	34	1377.246
#185	NFKB1	14	12	26	4428.577
#186	LMX1B	14	16	30	1687.045
#187	FOXF1	14	12	26	559.847
#188	KLF7	14	11	25	495.757
#189	GATAD1	14	12	26	760.678
#190	IRF9	14	14	28	1436.369
#191	CREBBP	14	19	33	1920.578
#192	TFAM	14	20	34	2166.822
#193	ARNTL	14	16	30	940.289
#194	FOXK2	14	13	27	1782.98
#195	HSF2	14	12	26	2574.778
#196	ZNF281	13	17	30	612.621
#197	CUX1	13	14	27	1015.032
#198	ELF2	13	24	37	2622.25
#199	TFEB	13	15	28	2347.727
#200	ZNF268	13	16	29	869.292
#201	ZNF207	13	9	22	562.228
#202	YY1	13	14	27	410.637
#203	TULP4	13	17	30	1920.888
#204	BCL3	13	17	30	2456.66
#205	GATA3	13	17	30	2863.199
#206	HCLS1	13	17	30	1149.884
#207	KLF2	13	8	21	1328.491
#208	NPAS1	13	17	30	1334.411
#209	EGR3	12	14	26	709.913
#210	TCF3	12	18	30	2454.426
#211	ATF5	12	12	24	1897.242
#212	IRF1	12	17	29	3129.735
#213	RXRB	12	10	22	5893.176
#214	NFX1	12	20	32	1416.905
#215	FLI1	12	17	29	629.712
#216	NR2F1	12	10	22	88.039
#217	SMAD1	12	12	24	1127.532
#218	PRDM2	12	17	29	2355.607
#219	ZFP36L1	12	17	29	2247.246
#220	ZBTB25	12	16	28	4783.262
#221	HOXC4	11	18	29	1856.897
#222	GTF2I	11	13	24	1179.06
#223	ELF1	11	10	21	338.395
#224	NFIX	11	16	27	149.257
#225	NFATC3	11	14	25	752.543
#226	TFDP3	11	13	24	190.192
#227	ELF4	11	13	24	4415.288
#228	SPEN	11	19	30	1322.299
#229	MYBL2	11	16	27	709.112
#230	GLI3	11	13	24	802.985
#231	RFX5	11	14	25	2682.739
#232	HMX1	11	13	24	552.23
#233	TBX6	11	15	26	285.738
#234	ESRRA	11	20	31	1779.368
#235	HHEX	11	17	28	3349.525
#236	CSDA	11	14	25	2246.224
#237	FOXM1	11	13	24	649.299
#238	SP140	11	12	23	508.544
#239	BACH1	11	22	33	3502.055
#240	CEBPD	11	17	28	994.885
#241	ZNF148	10	18	28	822.192
#242	CTBP1	10	12	22	429.124
#243	ZFP36L2	10	16	26	1394.645
#244	RXRA	10	18	28	670.806
#245	KDM5B	10	23	33	2326.359
#246	ZNF189	10	14	24	1051.667
#247	MNT	10	27	37	3559.842
#248	DBP	10	14	24	226.179
#249	PPARD	10	22	32	2359.739
#250	HMG20A	10	13	23	1254.335
#251	ZFHX3	10	8	18	5125.068
#252	BTAF1	10	16	26	582.757
#253	TBX21	10	18	28	621.272
#254	TP73	10	10	20	310.155
#255	TCFL5	10	18	28	1902.298
#256	IRF6	10	17	27	1205.221
#257	HOXC8	10	10	20	172.758
#258	XBP1	9	12	21	1045.092
#259	IKZF3	9	14	23	586.97
#260	HIRA	9	12	21	943.73
#261	NFE2L2	9	24	33	2151.116
#262	ESR1	9	9	18	109.436
#263	E2F5	9	21	30	1003.695
#264	SCAND1	9	22	31	1376.977
#265	CREB5	9	20	29	1758.315
#266	HOXB5	9	13	22	107.491
#267	FOSB	9	12	21	229.551
#268	HOPX	9	18	27	1627.838
#269	SNAPC2	9	13	22	258.12
#270	POU2F1	9	16	25	839.027
#271	ZNF274	9	15	24	1106.239
#272	MSX1	9	11	20	2264.627
#273	RORA	9	21	30	1886.414
#274	ZNF263	9	16	25	860.571
#275	NFIB	9	12	21	5218.826
#276	CDX2	8	11	19	645.66
#277	SOX4	8	15	23	1177.562
#278	TCF4	8	17	25	445.495
#279	EGR2	8	17	25	648.375
#280	ATF3	8	20	28	1013.879
#281	ELK3	8	21	29	2017.538
#282	RBPJ	8	18	26	3484.514
#283	C2orf3	8	15	23	1166.647
#284	TCF7	8	24	32	2784.518
#285	PRDM1	8	20	28	496.225
#286	TRIM22	8	16	24	1694.69
#287	PHTF1	8	17	25	2078.622
#288	E2F3	8	25	33	607.682
#289	HMGB2	8	17	25	410.199
#290	TCF15	8	16	24	1053.161
#291	PDX1	8	13	21	337.422
#292	FOXF2	8	14	22	4715.833
#293	TCF20	8	10	18	155.061
#294	STAT5B	8	17	25	999.422
#295	FOXC1	8	13	21	90.784
#296	TRIM29	8	20	28	291.572
#297	TFCP2L1	8	15	23	2995.309
#298	HNF4G	8	14	22	1331.288
#299	MYT1L	8	7	15	606.267
#300	LZTR1	8	11	19	11747.426
#301	SOX13	8	18	26	648.737
#302	E2F8	7	19	26	438.883
#303	ONECUT2	7	11	18	795.161
#304	MEF2A	7	25	32	5393.209
#305	SNAPC4	7	16	23	1104.319
#306	ZBTB38	7	12	19	635.922
#307	PLAG1	7	25	32	2161.129
#308	SREBF2	7	18	25	4352.54
#309	LHX2	7	19	26	4611.896
#310	ZNF157	7	9	16	482.758
#311	FOXJ1	7	16	23	5170.47
#312	CDKN2A	7	23	30	914.886
#313	TGIF2	7	19	26	511.413
#314	NOTCH1	7	16	23	942.457
#315	ZNF133	7	22	29	977.718
#316	FOXO1	7	20	27	1062.952
#317	POU6F1	7	13	20	145.035
#318	ZXDC	7	21	28	4087.256
#319	ZEB1	7	14	21	713.403
#320	SOX9	7	22	29	521.104
#321	ASCL1	7	16	23	341.725
#322	THRA	7	10	17	469.808
#323	CREB3L1	7	15	22	750.356
#324	BACH2	7	12	19	1293.323
#325	YEATS4	7	14	21	615.31
#326	ZNF175	7	15	22	965.16
#327	JUN	7	18	25	1665.891
#328	POU3F4	6	16	22	119.787
#329	GATA2	6	15	21	713.726
#330	AHCTF1	6	24	30	454.993
#331	CEBPB	6	20	26	1023.983
#332	TRIM28	6	19	25	2570.606
#333	RELB	6	17	23	869.568
#334	SCML1	6	14	20	163.301
#335	ZNF215	6	14	20	235.05
#336	NFYC	6	24	30	387.051
#337	ZGPAT	6	19	25	2065.59
#338	TSC22D3	6	21	27	1117.168
#339	FOXN3	6	23	29	813.222
#340	NFE2L1	6	15	21	286.931
#341	TRIM25	6	20	26	609.429
#342	ATF6	6	22	28	592.689
#343	PKNOX2	6	17	23	207.859
#344	TFDP2	6	17	23	367.633
#345	TAF4	6	20	26	489.046
#346	NFYA	6	22	28	1154.363
#347	TAF4B	6	22	28	2462.587
#348	ZSCAN16	6	14	20	269.785
#349	PRRX1	6	11	17	690.293
#350	SREBF1	5	19	24	1612.215
#351	ZNF394	5	20	25	1040.588
#352	HOXB2	5	15	20	288.436
#353	FOXJ3	5	20	25	763.547
#354	MEIS2	5	25	30	1618.892
#355	STAT6	5	13	18	267.639
#356	MYF6	5	12	17	219.816
#357	TP63	5	25	30	1997.642
#358	KDM5A	5	20	25	1404.255
#359	HSF1	5	22	27	380.166
#360	SOLH	5	16	21	1097.769
#361	FOXD1	5	11	16	217.196
#362	VENTX	5	14	19	442.511
#363	SOX15	5	17	22	755.41
#364	SUPT4H1	5	16	21	940.906
#365	TFAP2B	5	12	17	579.111
#366	KLF9	5	24	29	141.474
#367	MAF	5	11	16	71.372
#368	ADNP	5	22	27	873.543
#369	CBFB	5	15	20	793.978
#370	FOSL2	5	19	24	924.481
#371	ZNF93	5	11	16	52.951
#372	IKZF1	5	18	23	593.683
#373	MEF2D	5	16	21	386.698
#374	NFKB2	4	17	21	1164.614
#375	HDAC2	4	18	22	207.452
#376	NR2F2	4	22	26	3122.02
#377	ECSIT	4	18	22	467.16
#378	EHF	4	12	16	500.556
#379	VDR	4	12	16	183.924
#380	AHR	4	21	25	2018.344
#381	MSC	4	20	24	119.834
#382	SOX21	4	15	19	2079.452
#383	ZNF174	4	16	20	171.142
#384	SMAD3	4	22	26	755.623
#385	EGR1	4	19	23	1110.496
#386	IRF3	4	13	17	1345.402
#387	SMAD6	4	13	17	2896.893
#388	WNT5A	4	16	20	1532.118
#389	MGA	4	20	24	1594.654
#390	ETS1	4	13	17	443.445
#391	ESR2	4	18	22	629.475
#392	HOXA1	4	16	20	207.817
#393	LMO4	4	15	19	3239.192
#394	ZHX2	4	17	21	978.918
#395	PKNOX1	4	21	25	542.407
#396	KLF3	4	21	25	112.278
#397	ZNF117	4	21	25	352.682
#398	DMRT1	4	16	20	2856.05
#399	HDAC1	4	26	30	968.697
#400	NFIC	4	16	20	237.536
#401	EVX1	3	19	22	425.133
#402	DRAP1	3	16	19	1033.661
#403	ATOH1	3	11	14	143.947
#404	ETV6	3	19	22	399.77
#405	ZNF80	3	8	11	902.07
#406	MTF1	3	14	17	170.353
#407	LEF1	3	29	32	1379.844
#408	EPAS1	3	16	19	92.521
#409	SPIB	3	26	29	943.322
#410	NR2E3	3	12	15	45.49
#411	ELK4	3	23	26	2596.817
#412	SIX2	3	11	14	62.177
#413	CBFA2T2	3	17	20	3152.279
#414	HOXB7	3	21	24	147.887
#415	ZNF238	3	19	22	623.971
#416	HIC1	3	11	14	593.779
#417	RUNX2	3	16	19	263.344
#418	ZNF192	3	7	10	448.925
#419	CBFA2T3	3	25	28	512.045
#420	ZNF165	3	19	22	2286.434
#421	FOXG1	3	26	29	1461.432
#422	ARID3A	3	19	22	358.8
#423	CLOCK	3	20	23	152.803
#424	C11orf9	3	20	23	2667.78
#425	SCMH1	2	21	23	1214.031
#426	SLC30A9	2	17	19	188.464
#427	SATB1	2	19	21	216.754
#428	SNAPC5	2	19	21	107.096
#429	STAT2	2	15	17	129.175
#430	HOXA11	2	7	9	106.573
#431	FOS	2	14	16	142.621
#432	SOX30	2	10	12	942.399
#433	CTNNB1	2	14	16	622.361
#434	PCGF2	2	19	21	662.882
#435	RUNX1T1	2	7	9	38.808
#436	SIX3	2	20	22	682.853
#437	RUNX1	2	24	26	233.212
#438	RCAN1	2	20	22	218.54
#439	NFATC1	2	29	31	99.951
#440	GATAD2A	2	16	18	369.262
#441	PPARG	2	16	18	655.454
#442	HES1	2	20	22	539.017
#443	E2F2	2	21	23	61.9
#444	TSC22D1	2	20	22	100.179
#445	RNF4	2	17	19	289.683
#446	TRPS1	2	29	31	168.578
#447	ARNT	2	18	20	132.892
#448	ZNF434	2	18	20	1889.08
#449	PEG3	2	15	17	510.026
#450	ZNF33B	2	15	17	164.115
#451	CITED2	2	21	23	2532.533
#452	ALX3	2	15	17	63.094
#453	SALL2	2	23	25	107.4
#454	ISL1	2	8	10	843.756
#455	FOXO3	2	27	29	1480.793
#456	TFEC	2	20	22	1098.192
#457	ZNF643	2	17	19	1463.118
#458	HOXD3	2	8	10	26.568
#459	RELA	2	18	20	242.518
#460	TAF7	2	25	27	529.672
#461	ZSCAN18	1	18	19	64.885
#462	BTG2	1	18	19	35.063
#463	T	1	22	23	1026.741
#464	CIR1	1	18	19	34.558
#465	ETS2	1	14	15	35.595
#466	SALL1	1	3	4	528.798
#467	TCEAL1	1	19	20	97.242
#468	ZNF193	1	13	14	2188.327
#469	STAT4	1	18	19	657.438
#470	ETV5	1	17	18	273.668
#471	ZNF197	1	9	10	92.666
#472	ZNF75D	1	14	15	41.328
#473	TAF6	1	18	19	20.834
#474	PFDN1	1	16	17	1228.947
#475	KLF11	1	24	25	185.538
#476	NR1D2	1	18	19	39.695
#477	ZNF35	1	16	17	40.567
#478	SIM1	1	10	11	211.109
#479	PAX6	1	14	15	27.147
#480	HIF1A	1	21	22	92.207
#481	POU4F2	1	13	14	1975.666
#482	SCAND2	1	8	9	1516.816
#483	DDIT3	1	20	21	213.197
#484	BHLHE41	1	20	21	91.533
#485	CEBPE	1	15	16	28.871
#486	SOX2	1	14	15	4309.142
#487	ST18	1	5	6	31.873
#488	TAF1B	0	19	19	0
#489	ZBTB17	0	20	20	0
#490	AR	0	13	13	0
#491	ZNF85	0	20	20	0
#492	GTF2IRD1	0	20	20	0
#493	ZNF202	0	16	16	0
#494	HMBOX1	0	21	21	0
#495	ZNF167	0	22	22	0
#496	ETV7	0	25	25	0
#497	HOXD11	0	10	10	0
#498	IRF5	0	26	26	0
#499	TLX3	0	10	10	0
#500	SLC2A4RG	0	22	22	0