Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	HOXA11	70	2	72	6675.289
#2	HOXA10	53	6	59	3575.079
#3	SALL1	45	1	46	291.295
#4	RUNX1	42	3	45	3584.836
#5	LMO4	42	7	49	4665.163
#6	HOXA9	35	7	42	3099.998
#7	NFATC1	35	4	39	813.148
#8	ZNF193	35	5	40	6116.071
#9	MYCN	34	7	41	14300.603
#10	WT1	32	7	39	1827.501
#11	HOXD4	32	4	36	246.877
#12	IRF4	31	1	32	105.49
#13	GTF2IRD1	29	7	36	1294.056
#14	NKX3-2	29	7	36	676.653
#15	BCL11B	27	8	35	1065.272
#16	HSF2	27	9	36	10440.51
#17	TRIM28	27	6	33	1639.299
#18	ZHX2	26	5	31	688.932
#19	FOXF2	26	5	31	2101.251
#20	CEBPA	25	5	30	395.522
#21	ARNT2	24	8	32	2295.104
#22	EN2	24	4	28	180.425
#23	TBX2	24	8	32	2076.457
#24	BCL6	24	9	33	3016.734
#25	CITED1	23	4	27	566.867
#26	HNRNPK	23	5	28	1620.431
#27	EPAS1	23	11	34	1581.609
#28	CEBPB	22	9	31	2035.629
#29	NR2F1	22	11	33	1911.669
#30	SHOX	22	7	29	1264.694
#31	FOXD2	22	5	27	453.733
#32	YEATS4	22	3	25	1195.992
#33	SATB2	22	3	25	121.28
#34	STAT3	22	9	31	1030.646
#35	ZNF140	21	5	26	715.535
#36	LHX2	21	6	27	160.763
#37	ADNP	21	8	29	3724.395
#38	RARA	20	6	26	1562.646
#39	NR4A3	20	7	27	817.323
#40	TWIST1	20	6	26	3968.719
#41	SPEN	20	10	30	4995.777
#42	POU3F1	20	7	27	4251.52
#43	RELB	20	8	28	1130.329
#44	MYC	20	7	27	2523.259
#45	ZNF24	20	8	28	2195.451
#46	EVX1	20	2	22	1421.024
#47	IRX5	19	8	27	2810.091
#48	HOXA5	19	8	27	3545.517
#49	CUX2	19	8	27	696.536
#50	ZNF165	19	8	27	594.802
#51	ELF2	19	7	26	507
#52	SALL2	19	11	30	3211.116
#53	SOX11	19	11	30	1857.092
#54	TCF7L1	19	9	28	2138.343
#55	EGR3	18	5	23	809.739
#56	MAFB	18	5	23	454.64
#57	TCF21	18	7	25	8404.795
#58	SOX9	18	11	29	1985.745
#59	MEIS1	18	8	26	1701.998
#60	TULP4	18	9	27	998.415
#61	GABPB1	17	9	26	1793.312
#62	KLF9	17	11	28	4001.027
#63	LHX1	17	5	22	502.446
#64	MZF1	17	10	27	2649.023
#65	HOXB9	17	6	23	466.683
#66	CREBBP	17	8	25	1698.693
#67	NR3C1	17	8	25	1715.373
#68	STRN3	17	4	21	1829.31
#69	MEF2C	17	10	27	5399.34
#70	AR	17	4	21	677.265
#71	TGIF2	17	11	28	2042.678
#72	MLX	17	3	20	356.506
#73	LEF1	17	9	26	6141.171
#74	KLF2	17	14	31	5236.273
#75	NFIL3	17	9	26	1057.738
#76	PITX3	16	3	19	2003.293
#77	ZFHX3	16	5	21	1553.57
#78	GTF2H4	16	8	24	1153.145
#79	AEBP1	16	9	25	1077.601
#80	E2F5	16	7	23	1141.706
#81	TSC22D4	16	6	22	629.953
#82	ZNF217	16	9	25	1882.139
#83	HOXC4	16	10	26	447.965
#84	SCML1	16	12	28	948.835
#85	TCF3	16	8	24	2373.855
#86	HCLS1	16	8	24	964.168
#87	ATF5	16	9	25	4757.873
#88	TCF7	16	9	25	531.797
#89	NFE2L3	16	7	23	5547.877
#90	TAF4	16	10	26	904.642
#91	BACH2	15	14	29	1583.999
#92	EGR1	15	7	22	842.333
#93	WNT5A	15	12	27	2009.978
#94	RXRG	15	5	20	2839.084
#95	NPAS2	15	11	26	940.881
#96	MNX1	15	4	19	499.594
#97	MEOX1	15	11	26	2707.635
#98	CSDA	15	9	24	6834.156
#99	TAF10	15	11	26	1356.207
#100	FOXO1	15	10	25	1983.079
#101	HOXD10	15	7	22	486.38
#102	MLLT10	15	5	20	4982.326
#103	USF2	15	10	25	3974.118
#104	HMX1	14	6	20	1116.807
#105	MSX1	14	11	25	4135.476
#106	TLX3	14	8	22	2887.836
#107	TP53	14	10	24	2417.768
#108	CDKN2A	14	11	25	4500.927
#109	KLF4	14	12	26	386.117
#110	RERE	14	9	23	598.9
#111	HOXB5	14	7	21	1600.348
#112	ZNF91	14	13	27	1201.263
#113	MSL3	14	8	22	2911.008
#114	ZFPM2	14	7	21	2045.188
#115	STAT1	14	11	25	2966.341
#116	CREB3L1	14	11	25	1605.391
#117	HOXD3	14	13	27	1938.52
#118	TFAP2B	13	5	18	1939.18
#119	YY1	13	13	26	1602.863
#120	DRAP1	13	10	23	2013.923
#121	GATA6	13	6	19	1210.149
#122	HOXA4	13	5	18	301.507
#123	AFF1	13	7	20	2588.297
#124	NR1H3	13	8	21	1449.337
#125	BHLHE41	13	6	19	493.771
#126	SOX13	13	11	24	7005.001
#127	TAF12	13	9	22	2315.284
#128	FUBP1	13	15	28	1081.242
#129	SMAD6	13	10	23	1716.01
#130	TFEB	13	10	23	3301.164
#131	BACH1	13	9	22	1136.605
#132	SMAD3	13	6	19	4062.5
#133	CREB1	12	12	24	1210.899
#134	HIRA	12	6	18	470.871
#135	NR2C1	12	6	18	702.276
#136	AHR	12	13	25	4372.528
#137	NKX2-5	12	5	17	1471.676
#138	FOXD1	12	15	27	1546.523
#139	SUPT4H1	12	11	23	1820.871
#140	SOX4	12	16	28	5928.245
#141	ZSCAN16	12	11	23	1868.097
#142	SIX2	12	15	27	1164.811
#143	FOXO3	12	7	19	524.71
#144	KLF6	12	11	23	1716.518
#145	ADNP2	12	8	20	938.841
#146	C11orf9	12	5	17	360.626
#147	TSHZ2	12	7	19	405.759
#148	TCFL5	12	6	18	293.047
#149	GLI2	12	9	21	873.725
#150	PBX2	12	9	21	1049.864
#151	ETV4	12	9	21	775.409
#152	NR2F6	11	14	25	758.151
#153	FOXF1	11	6	17	57.397
#154	TBR1	11	7	18	3315.286
#155	SMAD4	11	5	16	551.288
#156	PITX1	11	9	20	326.733
#157	REST	11	6	17	1802.948
#158	STAT2	11	6	17	1279.555
#159	FOXC1	11	9	20	448.259
#160	HOXB7	11	8	19	993.198
#161	HOPX	11	7	18	822.216
#162	ZNF187	11	5	16	259.53
#163	TSC22D3	11	14	25	1979.885
#164	CREM	11	13	24	1748.514
#165	ZFHX4	11	12	23	2183.701
#166	NPAS1	11	10	21	1034.12
#167	SNAI2	11	10	21	926.727
#168	HOXB6	11	7	18	562.012
#169	NFIB	11	16	27	1065.559
#170	TCF25	11	13	24	2323.432
#171	E2F1	11	6	17	1087.595
#172	VAX2	11	10	21	220.505
#173	JUNB	11	5	16	2107.552
#174	NFYB	10	8	18	290.847
#175	HMGA2	10	13	23	4259.043
#176	PAX6	10	10	20	272.538
#177	ZNF444	10	8	18	1102.105
#178	PHTF1	10	7	17	1889.401
#179	ELK3	10	6	16	498.977
#180	HSF1	10	7	17	1347.259
#181	PTTG1	10	9	19	1652.184
#182	FOXA2	10	6	16	768.578
#183	BATF3	10	8	18	1100.476
#184	ATF2	10	7	17	1081.845
#185	FLI1	10	7	17	1297.152
#186	LZTS1	10	12	22	1700.58
#187	NFIC	10	11	21	1656.952
#188	NFE2L2	10	9	19	4058.705
#189	GATAD1	10	6	16	2534.493
#190	RORA	10	7	17	583.81
#191	FBXW7	10	10	20	2700.015
#192	KDM5A	10	15	25	1655.683
#193	TFAP2C	10	7	17	879.937
#194	RB1	9	10	19	2448.254
#195	CUX1	9	12	21	570.606
#196	KLF11	9	9	18	819.054
#197	VDR	9	4	13	1005.838
#198	PRRX1	9	11	20	931.092
#199	TSC22D2	9	15	24	5149.78
#200	BTAF1	9	9	18	1448.804
#201	ZNF135	9	5	14	843.183
#202	TGIF1	9	10	19	2654.951
#203	HMG20A	9	12	21	2143.514
#204	ZNF189	9	12	21	4515.304
#205	HES1	9	13	22	1129.029
#206	BCL3	9	12	21	1383.073
#207	NOLC1	9	12	21	1603.67
#208	SP3	9	12	21	2696.381
#209	MAF	9	8	17	837.376
#210	ARNTL	9	9	18	1539.644
#211	SUPT6H	9	9	18	2006.875
#212	STAT4	9	12	21	1956.679
#213	PAX8	9	10	19	1011.291
#214	SIX1	9	17	26	4288.592
#215	STAT5B	9	8	17	3409.029
#216	ETV1	9	13	22	3433.098
#217	KLF12	9	8	17	628.525
#218	RBCK1	9	8	17	435.863
#219	FOXJ2	9	7	16	1556.934
#220	ZBTB48	9	11	20	1100.695
#221	GTF2H3	9	6	15	1444.368
#222	HOXC13	9	8	17	1164.991
#223	ZNF207	9	9	18	1269.945
#224	MEOX2	8	5	13	445.693
#225	HOXD11	8	6	14	169.99
#226	RUNX1T1	8	16	24	1183.041
#227	FOS	8	6	14	700.08
#228	ETV5	8	17	25	885.669
#229	HOXD9	8	5	13	54.719
#230	NR4A2	8	10	18	1180.885
#231	CNBP	8	18	26	5713.179
#232	YBX1	8	10	18	3204.36
#233	TARDBP	8	13	21	1596.802
#234	SMAD2	8	11	19	895.787
#235	ELF1	8	15	23	2427.792
#236	ZSCAN18	8	10	18	2107.642
#237	SREBF1	8	12	20	1055.33
#238	HMG20B	8	5	13	467.751
#239	MAX	8	10	18	3785.439
#240	TAF5	8	11	19	3416.025
#241	ZNF281	8	10	18	2587.029
#242	HNF1B	8	9	17	3581.244
#243	IRF8	8	8	16	1386.455
#244	HOXC8	8	9	17	1748.676
#245	GATA1	8	5	13	1032.17
#246	ARNTL2	7	5	12	1962.767
#247	MSX2	7	9	16	1180.574
#248	HOXC5	7	4	11	193.178
#249	RARG	7	8	15	1503.832
#250	SLC30A9	7	10	17	1474.291
#251	AHCTF1	7	12	19	1150.326
#252	ARID4A	7	14	21	1816.764
#253	HOXB2	7	9	16	1792.985
#254	GATAD2A	7	13	20	1355.501
#255	ERF	7	9	16	2017.835
#256	PHOX2A	7	8	15	1542.36
#257	MGA	7	11	18	1219.927
#258	HSF4	7	9	16	1600.22
#259	HR	7	9	16	1419.845
#260	TRIM22	7	7	14	1133.426
#261	HHEX	7	6	13	1908.396
#262	HDAC1	7	10	17	792.214
#263	CBFA2T2	7	9	16	421.551
#264	PKNOX1	7	10	17	599.355
#265	NFKB1	7	13	20	1220.222
#266	E2F4	7	9	16	1909.437
#267	E2F6	7	10	17	841.36
#268	TBX3	7	15	22	5447.397
#269	ZNF219	7	12	19	1467.738
#270	NFYC	7	9	16	1621.354
#271	NR2F2	7	10	17	420.162
#272	TFAP2A	7	10	17	445.771
#273	FOXM1	7	8	15	989.355
#274	RELA	7	11	18	1059.07
#275	EGR2	7	10	17	375.52
#276	FOSL2	6	8	14	1865.728
#277	HCFC1	6	9	15	599.896
#278	TSC22D1	6	7	13	2018.751
#279	POU4F2	6	7	13	601.801
#280	IRF1	6	7	13	794.598
#281	TFDP1	6	12	18	1848.475
#282	PEG3	6	9	15	431.142
#283	BRD8	6	11	17	923.491
#284	ZFP36L2	6	12	18	1094.399
#285	HNRNPAB	6	10	16	606.346
#286	C2orf3	6	11	17	2823.263
#287	E2F3	6	10	16	833.813
#288	CNOT7	6	11	17	1674.869
#289	PA2G4	6	11	17	1605.503
#290	SNAPC4	6	10	16	1097.178
#291	NCOR1	6	9	15	699.603
#292	PKNOX2	6	10	16	280.208
#293	ENO1	6	13	19	1677.756
#294	NR3C2	6	11	17	2188.053
#295	KLF5	6	7	13	517.193
#296	CNOT8	6	10	16	1087.596
#297	ZNF236	6	6	12	1004.496
#298	GCFC1	6	11	17	334.646
#299	PHF1	6	4	10	180.701
#300	ETS2	6	11	17	2248.635
#301	CEBPD	6	13	19	1394.716
#302	ZNF85	6	11	17	827.113
#303	SOLH	6	9	15	1705.828
#304	ZNF148	6	15	21	1132.855
#305	ZXDC	6	7	13	303.165
#306	MMP14	6	6	12	833.276
#307	MYBL2	6	10	16	1341.585
#308	EMX1	6	7	13	1180.01
#309	ECSIT	6	13	19	2745.236
#310	PLAG1	5	15	20	6274.375
#311	MEIS3P1	5	8	13	654.973
#312	ZNF232	5	10	15	666.982
#313	EDF1	5	13	18	1256.834
#314	ZBTB38	5	15	20	4593.411
#315	ZNF83	5	13	18	632.761
#316	RCOR1	5	11	16	1355.192
#317	HMGB1	5	12	17	465.565
#318	STAT6	5	11	16	527.584
#319	TCF12	5	13	18	3074.183
#320	NFE2	5	9	14	4692.846
#321	TCF7L2	5	10	15	755.744
#322	RXRA	5	9	14	253.238
#323	POU4F1	5	3	8	244.993
#324	SMAD1	5	13	18	1118.15
#325	MITF	5	6	11	903.016
#326	NR1D2	5	10	15	2105.233
#327	BARX1	5	8	13	837.897
#328	HDAC2	5	11	16	669.701
#329	NFAT5	5	13	18	1557.815
#330	SOX17	5	6	11	1007.19
#331	HOXA7	5	10	15	605.268
#332	CREBZF	5	7	12	630.838
#333	ZNF167	5	9	14	478.957
#334	FOXN3	5	10	15	868.857
#335	SMAD5	5	8	13	4015.482
#336	CBFB	5	15	20	3132.003
#337	UBN1	5	9	14	738.098
#338	XBP1	5	13	18	651.048
#339	TRPS1	5	15	20	4793.66
#340	ZEB2	5	10	15	857.846
#341	ZNF238	5	13	18	3293.341
#342	ZEB1	5	13	18	1050.076
#343	FOXK2	5	13	18	5034.704
#344	TCEAL1	5	9	14	629.272
#345	PBX1	5	19	24	1445.755
#346	NR1H2	5	8	13	1439.392
#347	TAF7	5	13	18	1404.348
#348	HEY2	5	7	12	4295.71
#349	FOXG1	4	9	13	1109.124
#350	IRF7	4	8	12	515.153
#351	TFE3	4	7	11	546.225
#352	EN1	4	4	8	246.515
#353	ZNF117	4	14	18	2193.46
#354	TFCP2	4	12	16	1218.719
#355	TFAM	4	11	15	2319.319
#356	RCAN1	4	8	12	443.038
#357	LASS2	4	5	9	1628.471
#358	RNF4	4	8	12	1227.141
#359	HOXB3	4	13	17	229.638
#360	CREB5	4	15	19	3315.444
#361	SATB1	4	10	14	569.861
#362	ZNF131	4	9	13	713.765
#363	NFATC4	4	8	12	2192.407
#364	ZKSCAN1	4	7	11	209.239
#365	GATA4	4	6	10	729.879
#366	MEIS2	4	17	21	944.664
#367	ONECUT2	4	9	13	436.923
#368	TEAD4	4	9	13	173.016
#369	SCML2	4	10	14	559.481
#370	PLSCR1	4	12	16	1414.174
#371	ATF1	4	11	15	706.031
#372	HOXD1	4	9	13	433.056
#373	ESRRA	4	9	13	705.669
#374	HIC1	4	9	13	471.857
#375	LZTR1	4	7	11	286.643
#376	MAFF	4	14	18	1965.92
#377	PRDM2	4	13	17	3017.813
#378	TEAD3	4	6	10	108.768
#379	TP63	4	2	6	91.641
#380	HIF1A	4	10	14	1462.244
#381	HOXC11	4	12	16	155.191
#382	CSRNP3	4	12	16	1148.745
#383	HOXA6	4	8	12	3358.871
#384	UBP1	4	12	16	760.946
#385	HMGB2	4	18	22	2932.918
#386	MLL	4	12	16	458.624
#387	SCAND1	3	8	11	620.558
#388	HOXB13	3	12	15	1360.68
#389	HOXC10	3	13	16	356.402
#390	MEF2A	3	8	11	2055.955
#391	MSRB2	3	11	14	356.245
#392	ZNF93	3	15	18	1011.19
#393	NFYA	3	9	12	2695.101
#394	IRF6	3	13	16	669.607
#395	PBX3	3	13	16	1759.754
#396	FOXL2	3	8	11	130.183
#397	RUNX3	3	7	10	219.161
#398	CTBP1	3	15	18	3262.236
#399	NPAT	3	12	15	1914.028
#400	ZNF268	3	8	11	505.85
#401	KDM5B	3	15	18	2091.633
#402	RFXANK	3	13	16	705.606
#403	RFX5	3	9	12	543.064
#404	TADA3	3	8	11	178.442
#405	PURA	3	7	10	412.822
#406	JUN	3	12	15	253.561
#407	FOXJ3	3	13	16	835.073
#408	HIF3A	3	5	8	354.353
#409	HEY1	3	14	17	1142.2
#410	HLF	3	9	12	224.726
#411	ERG	3	7	10	1702.611
#412	ZIC1	3	8	11	2656.086
#413	CLOCK	3	9	12	390.887
#414	SOX15	3	7	10	281.764
#415	DLX2	3	13	16	207.515
#416	PPARD	3	8	11	520.98
#417	HOXA2	3	9	12	968.261
#418	HMBOX1	3	15	18	1887.851
#419	FOSB	3	4	7	98.221
#420	GATA2	3	8	11	130.719
#421	IRF2	3	12	15	1093.823
#422	TFDP2	2	11	13	759
#423	MECOM	2	9	11	1016.964
#424	PCGF2	2	12	14	186.535
#425	CREBL2	2	13	15	1548.87
#426	GAS7	2	9	11	287.657
#427	ELF3	2	6	8	1272.994
#428	TCF20	2	11	13	644.28
#429	ZNF274	2	8	10	1161.354
#430	ESRRG	2	14	16	1317.508
#431	PLAGL2	2	9	11	124.123
#432	SIM2	2	9	11	115.169
#433	ZNF277	2	6	8	48.82
#434	NKX3-1	2	5	7	608.057
#435	SOX12	2	6	8	684.735
#436	POU2F1	2	10	12	156.703
#437	HMGA1	2	11	13	138.71
#438	BNC1	2	9	11	2635.93
#439	ZNF75D	2	9	11	133.83
#440	ZNF45	2	12	14	377.893
#441	ISL1	2	15	17	3380.364
#442	ATF4	2	16	18	993.749
#443	CREB3L2	2	12	14	692.799
#444	ATF3	2	10	12	2422.84
#445	IRF3	2	13	15	184.735
#446	TCF4	2	8	10	170.136
#447	FOXC2	2	13	15	680.571
#448	PAX3	2	6	8	1067.952
#449	RBPJ	2	11	13	3108.606
#450	GLI3	2	9	11	397.529
#451	CTCF	2	12	14	143.017
#452	T	2	6	8	396.611
#453	TEAD1	2	9	11	815.849
#454	NFE2L1	2	8	10	114.997
#455	ATF6	2	12	14	697.993
#456	CITED2	2	18	20	862.306
#457	KLF7	2	13	15	280.659
#458	ZNF215	2	8	10	116.941
#459	GBX2	2	9	11	82.552
#460	NR5A2	2	9	11	475.701
#461	NR2E1	2	10	12	1495.7
#462	ZHX3	1	10	11	222.229
#463	NR4A1	1	15	16	471.746
#464	KLF3	1	12	13	73.759
#465	BTG2	1	9	10	95.673
#466	DBP	1	11	12	547.674
#467	DDIT3	1	12	13	477.658
#468	RARB	1	14	15	88.157
#469	ALX1	1	8	9	61.712
#470	DMTF1	1	14	15	177.021
#471	PITX2	1	8	9	373.775
#472	CTNNB1	1	16	17	766.17
#473	HOXA1	1	10	11	69.253
#474	TAF1B	1	13	14	119.159
#475	MTA1	1	12	13	51.676
#476	SOX18	1	8	9	97.37
#477	NOTCH1	1	12	13	952.553
#478	ASCL1	1	5	6	587.463
#479	BHLHE40	1	10	11	201.264
#480	TAF6	1	10	11	81.888
#481	CBFA2T3	1	10	11	408.417
#482	MYCL1	1	11	12	369.298
#483	CSRNP2	1	12	13	749.526
#484	KLF10	1	10	11	1143.666
#485	NFATC3	1	11	12	324.413
#486	ZFP36L1	1	10	11	54.346
#487	PRRX2	0	11	11	0
#488	AATF	0	8	8	0
#489	ELF4	0	9	9	0
#490	BUD31	0	11	11	0
#491	IRF9	0	11	11	0
#492	E2F8	0	10	10	0
#493	SNAPC5	0	9	9	0
#494	JUND	0	11	11	0
#495	SLC2A4RG	0	9	9	0
#496	PHOX2B	0	8	8	0
#497	SREBF2	0	13	13	0
#498	GATA3	0	10	10	0
#499	TCF15	0	17	17	0
#500	LASS6	0	12	12	0