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Hub Rank	Node	Children	Parents	Degree	Betweenness
#1	EGR1	66	4	70	1766.223
#2	TCFL5	53	2	55	1666.597
#3	STAT2	37	6	43	6681.61
#4	ZHX2	37	4	41	1994.454
#5	PBX3	36	5	41	7975.774
#6	CDKN2A	35	3	38	1993.571
#7	NKX2-5	34	5	39	2645.5
#8	LASS2	32	4	36	387.602
#9	PAX8	31	7	38	5528.534
#10	SIX1	30	3	33	2294.186
#11	PITX2	29	3	32	2164.791
#12	SCAND1	29	6	35	5371.488
#13	ZBTB38	28	2	30	592.978
#14	PROX1	28	2	30	1717.946
#15	PA2G4	28	7	35	4224.089
#16	ELF4	26	8	34	11759.968
#17	MYOG	25	9	34	2928.96
#18	ATF7	24	2	26	176.42
#19	SIN3A	24	11	35	3908.398
#20	MITF	24	8	32	4464.825
#21	PLSCR1	24	3	27	1389.291
#22	NFE2L2	23	3	26	4714.418
#23	SP1	23	4	27	1001.416
#24	IRF2	23	5	28	1472.456
#25	NFYA	23	4	27	981.535
#26	TSC22D1	22	1	23	1632.942
#27	ETS1	22	4	26	3502.671
#28	FOXN4	22	8	30	4031.538
#29	TAF5	22	3	25	761.191
#30	TGIF2	21	10	31	3561.087
#31	BRD8	21	8	29	2923.919
#32	KLF6	20	4	24	1388.632
#33	TCF3	20	6	26	726.33
#34	TRERF1	19	3	22	187.358
#35	IRF6	19	2	21	641.317
#36	ATF3	19	4	23	3526.954
#37	AHCTF1	19	4	23	1318.513
#38	ELK1	19	5	24	1120.318
#39	GTF2I	18	2	20	124.823
#40	BCL6	18	9	27	4523.831
#41	BUD31	18	5	23	2295.312
#42	KLF7	18	7	25	1940.72
#43	ZNF238	17	7	24	4861.431
#44	E2F5	17	8	25	2270.005
#45	FOSL1	17	5	22	1246.356
#46	PPARA	17	6	23	1012.529
#47	TP63	17	0	17	0
#48	ZFP36L2	17	7	24	5072.269
#49	HOXA7	17	4	21	4469.949
#50	TAF5L	17	4	21	631.71
#51	MAFF	17	6	23	921.047
#52	ZGLP1	17	8	25	1978.256
#53	TEAD3	17	7	24	10375.921
#54	PHTF1	17	5	22	4453.026
#55	FOXN1	16	5	21	573.894
#56	EHF	16	3	19	203.078
#57	GATAD2A	16	7	23	8214.732
#58	ETV6	16	8	24	5074.498
#59	PKNOX2	16	6	22	1165.784
#60	ETV5	16	5	21	2934.669
#61	ZKSCAN4	16	7	23	2294.489
#62	MAX	16	7	23	1207.498
#63	AFF4	16	9	25	1143.142
#64	KLF12	15	4	19	4938.17
#65	ZNF148	15	3	18	5788.871
#66	WNT5A	15	4	19	1663.127
#67	PCGF2	14	3	17	287.461
#68	BACH1	14	8	22	2349.959
#69	GATA2	14	4	18	2081.865
#70	TFEB	14	5	19	3480.331
#71	DDIT3	14	6	20	8064.526
#72	XBP1	14	9	23	1859.541
#73	PAX6	14	5	19	2612.462
#74	RORC	14	11	25	2273.419
#75	FOXC2	14	3	17	472.311
#76	GCFC1	14	10	24	16992.348
#77	KLF5	13	7	20	3585.681
#78	ETV1	13	9	22	14165.383
#79	TBX10	13	9	22	845.892
#80	PAX5	13	5	18	2396.4
#81	ARID4A	13	6	19	456.422
#82	PURB	13	8	21	1552.056
#83	RAX2	13	6	19	751.122
#84	ZNF207	13	7	20	2616.842
#85	NFYC	13	7	20	2978.241
#86	MYC	13	5	18	3964.977
#87	PHF1	13	7	20	2822.296
#88	EGR4	13	12	25	1458.185
#89	USF2	12	9	21	4096.437
#90	ZNF394	12	4	16	1193.603
#91	MBD1	12	3	15	750.991
#92	SIX4	12	8	20	2619.477
#93	CBFB	12	4	16	127.458
#94	KLF10	12	3	15	257.185
#95	FOXD1	12	9	21	2293.351
#96	DMRT2	12	4	16	228.874
#97	RFX5	11	6	17	500.293
#98	NFIA	11	7	18	401.331
#99	USF1	11	6	17	2620.198
#100	AHR	11	4	15	4757.238
#101	TCEAL1	11	5	16	1647.953
#102	ZNF628	11	8	19	30558.705
#103	ZHX3	11	6	17	1130.385
#104	THRB	11	7	18	4734.076
#105	EOMES	11	8	19	8443.833
#106	ZSCAN18	11	7	18	2114.568
#107	MTA1	11	7	18	1631.998
#108	TRIM25	11	2	13	200.004
#109	NFIB	11	12	23	5597.766
#110	HOXA10	11	7	18	2911.096
#111	ASCL1	10	7	17	6945.442
#112	RB1	10	2	12	27.958
#113	SOX13	10	7	17	1500.152
#114	HOXA5	10	7	17	3763.151
#115	DLX1	10	8	18	596.111
#116	GLI3	10	3	13	165.753
#117	ZNF445	10	6	16	869.192
#118	ZNF449	10	6	16	1376.265
#119	SOX12	10	10	20	2171.677
#120	KDM5A	10	6	16	572.169
#121	ZNF91	10	10	20	5868.351
#122	ZIC2	10	6	16	5762.436
#123	MESP1	10	5	15	1518.31
#124	BATF3	10	8	18	562.89
#125	ELF1	10	4	14	312.367
#126	E2F8	10	5	15	2736.088
#127	ATF1	10	6	16	4053.446
#128	RUNX3	9	8	17	1343.256
#129	CREBZF	9	6	15	4871.526
#130	CREB1	9	5	14	1644.671
#131	NFE2L3	9	6	15	737.096
#132	SIM1	9	9	18	3111.637
#133	ZNF232	9	10	19	3737.016
#134	TCF15	9	9	18	700.395
#135	ARNTL	9	7	16	1960.774
#136	VDR	9	8	17	695.594
#137	ZNF138	9	7	16	1069.853
#138	LASS6	9	7	16	66.704
#139	CTBP1	9	3	12	479.955
#140	NR4A1	8	6	14	193.773
#141	MYPOP	8	8	16	1014.915
#142	MAFB	8	12	20	3671.373
#143	SOLH	8	5	13	739.201
#144	GTF2H4	8	5	13	243.825
#145	SOX2	8	9	17	717.298
#146	SOX6	8	8	16	1525.525
#147	ZIC1	8	5	13	554.416
#148	BHLHE41	8	8	16	3626.426
#149	DLX2	8	5	13	512.421
#150	TSHZ1	8	8	16	1300.819
#151	FOXP4	8	7	15	821.727
#152	REST	8	5	13	383.646
#153	STAT1	8	9	17	30694.204
#154	HIF3A	8	9	17	912.835
#155	GATAD1	8	5	13	3071.247
#156	MAF	8	12	20	3112.793
#157	FOXL2	8	8	16	4012.334
#158	HNF4A	8	6	14	504.395
#159	TP53	8	7	15	2299.699
#160	TCF21	8	5	13	6086.942
#161	TFE3	8	6	14	1126.312
#162	MECOM	7	7	14	331.465
#163	FOXJ2	7	5	12	2882.068
#164	ZNF33A	7	6	13	3765.103
#165	FOXO3	7	8	15	3013.199
#166	JUN	7	7	14	459.296
#167	TBX1	7	10	17	1035.738
#168	ATF2	7	7	14	829.748
#169	SOX9	7	11	18	5730.334
#170	HOXB13	7	7	14	354.187
#171	MEIS1	7	8	15	5027.075
#172	SOX7	7	5	12	2892.462
#173	TWIST1	7	8	15	1487.779
#174	KLF3	7	7	14	4767.718
#175	E2F2	7	3	10	2074.183
#176	RUNX1	7	12	19	2009.205
#177	RUNX2	7	10	17	5489.169
#178	DLX6	7	7	14	2595.029
#179	TWIST2	7	8	15	1198.542
#180	NFATC1	7	9	16	928.12
#181	CREM	7	7	14	2609.911
#182	HOXB9	7	11	18	7433.735
#183	PDX1	7	8	15	809.892
#184	ETV4	7	7	14	4015.57
#185	RARA	7	8	15	6455.037
#186	TFDP1	7	11	18	11489.415
#187	SREBF1	7	5	12	749.096
#188	ZNF434	7	6	13	420.566
#189	MEIS2	6	11	17	374.151
#190	ISL2	6	7	13	872.316
#191	CSRNP2	6	3	9	519.311
#192	HOPX	6	8	14	10225.732
#193	HMGA2	6	13	19	1293.975
#194	MSC	6	9	15	10221.148
#195	ZNF496	6	5	11	1235.289
#196	PRDM1	6	4	10	356.845
#197	ZKSCAN1	6	8	14	120.625
#198	BCL11B	6	6	12	580.251
#199	TBX3	6	9	15	690.577
#200	ZNF193	6	6	12	143.116
#201	SMAD1	6	9	15	1260.867
#202	ZNF277	6	7	13	160.616
#203	GTF2H2	6	4	10	261.965
#204	ATF5	6	12	18	14745.738
#205	ZNF197	6	8	14	920.493
#206	GATA4	6	8	14	1515.841
#207	MYF6	6	8	14	3944.075
#208	ETS2	6	6	12	879.66
#209	NOLC1	6	4	10	399.852
#210	THRA	6	5	11	4726.451
#211	ATF6B	5	7	12	726.676
#212	CREB3L2	5	4	9	557.588
#213	SNAPC2	5	10	15	1215.447
#214	FOXK2	5	9	14	13301.069
#215	TSHZ2	5	5	10	367.099
#216	TULP4	5	2	7	66.693
#217	EPAS1	5	7	12	722.882
#218	ZFP36L1	5	9	14	10329.451
#219	SPEN	5	3	8	645.38
#220	HOXB8	5	11	16	2234.21
#221	HMX1	5	8	13	1057.614
#222	HIRA	5	8	13	941.745
#223	TEAD1	5	6	11	364.553
#224	GTF2H3	5	7	12	232.846
#225	SUPT6H	5	10	15	1414.419
#226	HSF1	5	6	11	99.649
#227	NR1D2	5	8	13	3285.815
#228	HOXB1	5	9	14	741.516
#229	TCF4	5	10	15	12956.827
#230	BHLHE40	5	10	15	4293.504
#231	HOXB4	5	7	12	1255.812
#232	NFX1	5	8	13	1804.053
#233	ZSCAN5A	5	7	12	1245.059
#234	HDAC2	5	8	13	381.783
#235	E2F1	5	4	9	265.604
#236	VENTX	5	6	11	262.679
#237	BLZF1	5	7	12	558.02
#238	ZXDC	5	4	9	496.805
#239	MLLT10	5	10	15	567.049
#240	LHX1	5	7	12	221.719
#241	ZFP37	5	6	11	224.914
#242	SMAD5	5	11	16	248.103
#243	HMGB2	5	10	15	1164.764
#244	HOXD10	5	10	15	4257.669
#245	NRL	5	5	10	439.557
#246	NFKB2	4	5	9	833.924
#247	HOXC10	4	10	14	202.035
#248	HOXA3	4	12	16	147.919
#249	ZNF438	4	5	9	331.854
#250	GABPA	4	9	13	111.432
#251	PKNOX1	4	8	12	462.159
#252	ZNF268	4	7	11	1213.294
#253	FLI1	4	3	7	575.956
#254	MXD1	4	10	14	2611.916
#255	CBL	4	9	13	5310.674
#256	MLXIPL	4	6	10	310.534
#257	KLF16	4	6	10	613.495
#258	ZNF192	4	7	11	1094.326
#259	SATB1	4	9	13	124.161
#260	SIX5	4	11	15	2940.38
#261	RARG	4	9	13	347.549
#262	ZKSCAN2	4	8	12	10008.858
#263	RCAN1	4	9	13	562.756
#264	ZNF367	4	10	14	220.033
#265	FOXJ1	4	12	16	3420.006
#266	TFDP2	4	8	12	26164.651
#267	GABPB1	4	7	11	468.77
#268	TCF19	4	6	10	770.897
#269	HEY1	4	8	12	4695.91
#270	FOXM1	4	8	12	5480.163
#271	HOXB5	4	7	11	1452.524
#272	SP3	4	9	13	8516.519
#273	ZHX1	4	6	10	266.672
#274	MAFG	4	11	15	2396.674
#275	RXRB	4	6	10	9800.659
#276	HOXD13	4	7	11	509.407
#277	HOXD1	4	9	13	6246.214
#278	IRF1	4	6	10	1506.547
#279	SMAD6	4	6	10	328.315
#280	KLF17	4	4	8	554.077
#281	HR	4	10	14	1285.709
#282	BACH2	4	3	7	25.614
#283	CTNNB1	4	7	11	1763.808
#284	FOXN3	4	7	11	2195.581
#285	MLL	3	7	10	310.673
#286	HMGA1	3	4	7	159.481
#287	PITX1	3	6	9	99.806
#288	MNX1	3	8	11	1488.713
#289	HOXA2	3	4	7	3849.9
#290	ZNF24	3	5	8	66.539
#291	TSC22D3	3	7	10	3648.19
#292	IRF9	3	5	8	523.431
#293	FOXF2	3	8	11	30743.449
#294	BCL3	3	8	11	1561.646
#295	ZNF83	3	7	10	760.87
#296	ERF	3	10	13	401.19
#297	TCF7L2	3	5	8	221.496
#298	CREB5	3	6	9	164.82
#299	ZKSCAN3	3	6	9	215.58
#300	KLF15	3	7	10	1275.618
#301	SLC30A9	3	3	6	20.431
#302	TBX2	3	5	8	135.773
#303	ZNF281	3	7	10	80.544
#304	NFAT5	3	7	10	2838.918
#305	HOXC11	3	7	10	170.555
#306	CEBPA	3	8	11	818.042
#307	CSDA	3	9	12	12033.036
#308	ZFPM1	3	8	11	137.076
#309	PLAG1	3	9	12	653.899
#310	PBX1	3	6	9	236.446
#311	TEAD2	3	12	15	374.693
#312	RFXAP	3	11	14	714.105
#313	E2F7	3	12	15	612.204
#314	TCF25	3	10	13	540.552
#315	KLF4	3	8	11	149.332
#316	HNF1B	3	7	10	715.907
#317	NR2F2	3	10	13	633.454
#318	TFAM	3	9	12	762.232
#319	HES1	3	10	13	281.441
#320	TRIM22	3	1	4	0.85
#321	POU6F1	3	7	10	179.993
#322	SIM2	3	8	11	1564.31
#323	ARNTL2	3	9	12	1833.063
#324	NKX3-1	3	6	9	1613.385
#325	FOXJ3	3	7	10	170.624
#326	ISL1	3	9	12	355.134
#327	FUBP1	3	8	11	431.793
#328	TADA2A	3	8	11	633.831
#329	ELK4	3	6	9	2225.789
#330	NR2F6	3	6	9	1811.769
#331	TRPS1	3	10	13	2791.454
#332	SATB2	3	8	11	834.574
#333	FOSL2	2	8	10	8797.303
#334	KLF9	2	7	9	1220.733
#335	ZNF33B	2	5	7	119.437
#336	ZNF75D	2	4	6	25.844
#337	ASCL2	2	7	9	831.175
#338	HOXD8	2	6	8	49.421
#339	ZNF41	2	10	12	912.076
#340	FOS	2	11	13	3337.778
#341	NR2F1	2	4	6	97.317
#342	CITED2	2	9	11	6737.784
#343	TAF4B	2	6	8	2640.293
#344	ZNF19	2	7	9	765.2
#345	TSC22D2	2	9	11	817.345
#346	T	2	9	11	1339.997
#347	SRF	2	6	8	78.652
#348	PURA	2	7	9	273.909
#349	PBX4	2	5	7	158.283
#350	TAF1B	2	6	8	114.754
#351	IRF5	2	6	8	281.415
#352	DBP	2	11	13	1046.174
#353	NFATC3	2	5	7	108.489
#354	SPIB	2	8	10	229.243
#355	MYCL1	2	6	8	170.13
#356	NPAS2	2	6	8	161.622
#357	RFX1	2	6	8	1170.41
#358	ENO1	2	8	10	393.145
#359	ZNF165	2	5	7	88.048
#360	FOXH1	2	5	7	655.45
#361	MIXL1	2	6	8	238.347
#362	SALL2	2	5	7	817.302
#363	UBN1	2	7	9	8186.886
#364	ZNF131	2	7	9	85.514
#365	TBX4	2	8	10	4107.328
#366	ZFHX4	2	10	12	302.553
#367	LCOR	2	4	6	215.206
#368	LEF1	2	11	13	200.181
#369	HMG20B	2	9	11	76.669
#370	GSX1	2	5	7	272.548
#371	ONECUT2	2	9	11	3719.525
#372	FBXW7	2	8	10	688.36
#373	ZSCAN20	2	5	7	154.118
#374	HNF1A	2	9	11	1679.767
#375	TCF7L1	2	11	13	491.111
#376	TFAP2C	2	10	12	325.425
#377	POU3F1	2	7	9	61.258
#378	NKX2-1	2	2	4	64.302
#379	PPARD	2	6	8	25.765
#380	ZNF117	2	6	8	13578.267
#381	MMP14	2	9	11	261.452
#382	CSRNP1	2	4	6	8.659
#383	MSX1	2	12	14	1583.273
#384	SOX4	2	7	9	276.08
#385	TEF	2	7	9	285.121
#386	NR4A3	2	5	7	30.469
#387	SPI1	2	6	8	187.925
#388	SMAD3	2	8	10	163.437
#389	HSF2	2	10	12	413.482
#390	NR6A1	1	5	6	34.035
#391	ZEB1	1	9	10	5527.492
#392	FOXC1	1	8	9	272.325
#393	TGIF1	1	10	11	301.376
#394	MYNN	1	8	9	507.211
#395	ZNF397	1	9	10	22.895
#396	ARNT	1	7	8	46.001
#397	FOXA2	1	8	9	63.811
#398	RERE	1	7	8	3139.267
#399	ELK3	1	10	11	181.495
#400	EGR3	1	5	6	8.746
#401	NFIC	1	10	11	108.442
#402	KLF2	1	7	8	57.794
#403	TRIM29	1	11	12	123.868
#404	CNOT7	1	7	8	238.017
#405	ZXDA	1	10	11	1939.865
#406	HES5	1	8	9	62.419
#407	ZFHX3	1	9	10	87.244
#408	ZNF174	1	2	3	6.301
#409	C5orf41	1	9	10	250.208
#410	ESR1	1	6	7	11.4
#411	SIX2	1	8	9	768.289
#412	IRX5	1	9	10	120.78
#413	CBFA2T2	1	4	5	58.06
#414	ZNF643	1	5	6	36.013
#415	CSRNP3	1	6	7	60.834
#416	DLX3	1	6	7	23181.043
#417	STAT5B	1	6	7	10.82
#418	ARID3A	1	12	13	85.367
#419	TP73	1	9	10	19.969
#420	YY1	1	7	8	98.024
#421	ZNF140	1	8	9	20.355
#422	TFAP2A	1	11	12	27.745
#423	POU2F1	1	3	4	548.379
#424	IKZF1	1	11	12	120.961
#425	POU2F2	1	7	8	267.135
#426	EGR2	1	9	10	166.609
#427	ZNF70	1	8	9	264.882
#428	FOXE1	1	4	5	32.89
#429	NR4A2	1	8	9	53.35
#430	RARB	1	11	12	334.759
#431	MEF2D	1	9	10	288.247
#432	HCLS1	1	5	6	492.105
#433	TADA3	1	9	10	378.724
#434	JDP2	1	7	8	125.655
#435	ZNF71	1	7	8	84.76
#436	HOXC9	1	7	8	68.958
#437	GBX1	1	5	6	70.339
#438	NOTCH1	1	7	8	54.46
#439	NFIX	1	8	9	133.126
#440	ZNF323	1	5	6	206.785
#441	NKX6-1	1	7	8	205.298
#442	SOX11	1	5	6	966.557
#443	MEF2A	1	6	7	1019.624
#444	TCF7	1	5	6	2030.973
#445	FOXP1	1	10	11	122.48
#446	RORA	1	5	6	31.287
#447	CCRN4L	1	11	12	4412.988
#448	ELF2	1	9	10	41.641
#449	CREB3L4	1	4	5	436.238
#450	ATF6	0	8	8	0
#451	TAL1	0	8	8	0
#452	SOX1	0	7	7	0
#453	OVOL1	0	13	13	0
#454	BTG2	0	9	9	0
#455	SLC2A4RG	0	7	7	0
#456	SALL1	0	7	7	0
#457	REL	0	7	7	0
#458	CEBPD	0	11	11	0
#459	GRHL3	0	6	6	0
#460	ZNF92	0	7	7	0
#461	TAF10	0	6	6	0
#462	FOXO1	0	5	5	0
#463	ETV2	0	7	7	0
#464	ETV3	0	6	6	0
#465	FOSB	0	9	9	0
#466	ZNF256	0	10	10	0
#467	NR5A1	0	4	4	0
#468	MGA	0	9	9	0
#469	TCF12	0	7	7	0
#470	JUND	0	13	13	0
#471	HOXB6	0	12	12	0
#472	TAF13	0	6	6	0
#473	HIC1	0	7	7	0
#474	BATF2	0	3	3	0
#475	HOXA11	0	9	9	0
#476	MTA2	0	7	7	0
#477	EN2	0	6	6	0
#478	MEOX1	0	4	4	0
#479	NPAS1	0	5	5	0
#480	FOXF1	0	5	5	0
#481	VSX1	0	7	7	0
#482	HOXA4	0	6	6	0
#483	PAX7	0	8	8	0
#484	PBX2	0	5	5	0
#485	ZSCAN2	0	4	4	0
#486	HAND2	0	5	5	0
#487	ZRANB2	0	7	7	0
#488	LMO4	0	2	2	0
#489	NKX6-2	0	7	7	0
#490	NFATC2	0	6	6	0
#491	HOXA9	0	9	9	0
#492	MEIS3P1	0	8	8	0
#493	RCOR1	0	7	7	0
#494	SMAD9	0	9	9	0
#495	TARDBP	0	10	10	0
#496	IKZF4	0	7	7	0
#497	ZNF219	0	7	7	0
#498	SCRT1	0	7	7	0
#499	SMAD4	0	6	6	0
#500	FOXN2	0	4	4	0