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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE15966_top500tf - GSE15966 - SiGN-BN HC+Bootstrap
Network DescriptionGene expression signature predictive of rapid response to imatinib mesylate in Gastrointestinal Stromal Tumor (GIST)
NodeNOTCH1

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Upstream (Parents)
   (<<)    NR3C1 → NOTCH1
   (<<)    EGR1 → NOTCH1
   (<<)    MYF5 → NOTCH1
   (<<)    MKX → NOTCH1
   (<<)    FOXL2 → NOTCH1
   (<<)    ZSCAN2 → NOTCH1
   (<<)    AR → NOTCH1
   (<<)    ZSCAN20 → NOTCH1
   (<<)    ZEB2 → NOTCH1
   (<<)    FOXA2 → NOTCH1
   (<<)    HOMEZ → NOTCH1

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Downstream (Children)
   NOTCH1 → SMAD3    (>>)
   NOTCH1 → HCFC1    (>>)
   NOTCH1 → SOLH    (>>)
   NOTCH1 → ZNF18    (>>)
   NOTCH1 → ESR2    (>>)
   NOTCH1 → POU1F1    (>>)
   NOTCH1 → MNT    (>>)
   NOTCH1 → BRD8    (>>)
   NOTCH1 → NFIA    (>>)
   NOTCH1 → GATAD2A    (>>)
   NOTCH1 → ZNF445    (>>)
   NOTCH1 → ZNF498    (>>)
   NOTCH1 → HOXB4    (>>)
   NOTCH1 → MEF2D    (>>)