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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE10780_egf1520 - GSE10780 - SiGN-BN HC+Bootstrap
Network DescriptionProliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue
NodePAK1

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Upstream (Parents)
   (<<)    ATF2 → PAK1
   (<<)    BCL2 → PAK1
   (<<)    BMPR1A → PAK1
   (<<)    CALM3 → PAK1
   (<<)    CREBBP → PAK1
   (<<)    CRK → PAK1
   (<<)    CRLF3 → PAK1
   (<<)    DYRK1A → PAK1
   (<<)    HDAC5 → PAK1
   (<<)    ITCH → PAK1
   (<<)    LRP3 → PAK1
   (<<)    MAP3K1 → PAK1
   (<<)    MAPK3 → PAK1
   (<<)    MAPK9 → PAK1
   (<<)    MTMR6 → PAK1
   (<<)    NAPRT1 → PAK1
   (<<)    PABPC3 → PAK1
   (<<)    PLA2G12A → PAK1
   (<<)    PPP1CA → PAK1
   (<<)    PTRF → PAK1
   (<<)    RFFL → PAK1
   (<<)    RNF111 → PAK1
   (<<)    RRAS → PAK1
   (<<)    TPM4 → PAK1
   (<<)    TTC9 → PAK1
   (<<)    VEGFB → PAK1

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Downstream (Children)
   PAK1 → ANKRD27    (>>)
   PAK1 → APLN    (>>)
   PAK1 → ATP2B1    (>>)
   PAK1 → DKFZP434I0714    (>>)
   PAK1 → EIF2AK2    (>>)
   PAK1 → FZD6    (>>)
   PAK1 → IMPA1    (>>)
   PAK1 → INF2    (>>)
   PAK1 → ITPR2    (>>)
   PAK1 → MAPK8    (>>)
   PAK1 → MMP15    (>>)
   PAK1 → MMP17    (>>)
   PAK1 → RASSF1    (>>)
   PAK1 → RDH16    (>>)
   PAK1 → RHOT2    (>>)
   PAK1 → SGSH    (>>)
   PAK1 → SIN3A    (>>)
   PAK1 → SMAD1    (>>)
   PAK1 → SOCS6    (>>)
   PAK1 → SULT1A2    (>>)
   PAK1 → THBS1    (>>)
   PAK1 → TMEM154    (>>)
   PAK1 → TOP2B    (>>)
   PAK1 → UBE2D2    (>>)
   PAK1 → WNT3    (>>)
   PAK1 → ZNF365    (>>)