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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE20842_egf1520 - GSE20842 - SiGN-BN HC+Bootstrap
Network DescriptionMutated KRAS induces overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas
NodePAK1

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Upstream (Parents)
   (<<)    COTL1 → PAK1
   (<<)    DUSP9 → PAK1
   (<<)    EWSR1 → PAK1
   (<<)    FOXO3 → PAK1
   (<<)    GNB1 → PAK1
   (<<)    GRK5 → PAK1
   (<<)    HDAC11 → PAK1
   (<<)    HSPA1A → PAK1
   (<<)    LCE3D → PAK1
   (<<)    MAPK8 → PAK1
   (<<)    MAPKAP1 → PAK1
   (<<)    MYL7 → PAK1
   (<<)    MYO10 → PAK1
   (<<)    PCK2 → PAK1
   (<<)    PCSK7 → PAK1
   (<<)    PLCB3 → PAK1
   (<<)    PLCH2 → PAK1
   (<<)    PPP1CA → PAK1
   (<<)    RASSF5 → PAK1
   (<<)    TPM3 → PAK1
   (<<)    WNT5A → PAK1

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Downstream (Children)
   PAK1 → EHD1    (>>)
   PAK1 → ELF3    (>>)
   PAK1 → HSPA4    (>>)
   PAK1 → ICAM2    (>>)
   PAK1 → LYPLA2    (>>)
   PAK1 → MAPK1    (>>)
   PAK1 → MAPK13    (>>)
   PAK1 → RAC2    (>>)
   PAK1 → SEPW1    (>>)
   PAK1 → SOS1    (>>)
   PAK1 → STAT3    (>>)
   PAK1 → VPS37B    (>>)