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TCNG: The Cancer Network Galaxy
Tcng

TCNG The Cancer Network Galaxy0.14

Database of Cancer Gene Networks from Public Gene Expression Data

Edges in Network

NetworkGSE20842_top500tf - GSE20842 - SiGN-BN HC+Bootstrap
Network DescriptionMutated KRAS induces overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas
NodeE2F5

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Upstream (Parents)
   (<<)    FOXQ1 → E2F5
   (<<)    ASCL2 → E2F5
   (<<)    ETV4 → E2F5
   (<<)    NR3C2 → E2F5
   (<<)    GRHL3 → E2F5
   (<<)    NFE2L3 → E2F5
   (<<)    TEAD4 → E2F5
   (<<)    SIM2 → E2F5
   (<<)    FOXO1 → E2F5
   (<<)    BATF3 → E2F5
   (<<)    NOLC1 → E2F5
   (<<)    KLF9 → E2F5
   (<<)    MAF → E2F5
   (<<)    PBX1 → E2F5
   (<<)    CBFB → E2F5
   (<<)    ZNF24 → E2F5
   (<<)    E2F6 → E2F5
   (<<)    ZNF643 → E2F5
   (<<)    AATF → E2F5

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Downstream (Children)
   E2F5 → CREB3L3    (>>)
   E2F5 → SOX2    (>>)
   E2F5 → HOXA2    (>>)
   E2F5 → MEIS2    (>>)
   E2F5 → IRF9    (>>)
   E2F5 → BARX1    (>>)
   E2F5 → CREBZF    (>>)